Mutagenetix

Phenotypic Mutation Search
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Gene Symbol
Gene Name
Allele
Institutional Source
Author
Chromosome
Type of Mutation
DNA Base Change (assembly)	⇒
Amino Acid Change	changed to
Mode of Inheritance
Phenotypic Category	Match selected phenotypes
Repository
Pedigree
Photo
Last Update	-

125-03 Response - decreased
125-03 Response - increased
30 min GTT hyperglycemic
30 min GTT hyperglycemic (male)
30 min GTT hyperoglycemic (female)
30 min GTT hypoglycemic
30 min GTT hypoglycemic (female)
30 min GTT hypoglycemic (male)
adenovirus infection of macrophages - decreased
adenovirus infection of macrophages - increased
adipose tissue
anemia
Anophthalmia
Aut: Interaction - decreased
Aut: Interaction - increased
autoimmunity
behavior/neurological
Blood Analysis: EO% - decreased
Blood Analysis: EO% - increased
Blood Analysis: Hb - decreased
Blood Analysis: Hb - increased
Blood Analysis: HCT - decreased
Blood Analysis: HCT - increased
Blood Analysis: LY# - decreased
Blood Analysis: LY# - increased
Blood Analysis: MCH - decreased
Blood Analysis: MCH - increased
Blood Analysis: MCHC - decreased
Blood Analysis: MCHC - increased
Blood Analysis: MCV - decreased
Blood Analysis: MCV - increased
Blood Analysis: MO# - decreased
Blood Analysis: MO# - increased
Blood Analysis: NE# - decreased
Blood Analysis: NE# - increased
Blood Analysis: Platelet Count - decreased
Blood Analysis: Platelet Count - increased
Blood Analysis: RBC - decreased
Blood Analysis: RBC - increased
Blood Analysis: RDW - decreased
Blood Analysis: RDW - increased
Blood Analysis: WBC - decreased
Blood Analysis: WBC - increased
Blood Pressure: Pooled HR - decreased
Blood Pressure: Pooled HR - increased
Blood Pressure: Pooled SBP - decreased
Blood Pressure: Pooled SBP - increased
Body Weight - decreased
Body Weight - increased
Body Weight (BP, z-score, female) - decreased
Body Weight (BP, z-score, female) - increased
Body Weight (BP, z-score, male) - decreased
Body Weight (BP, z-score, male) - increased
Body Weight (Female) - decreased
Body Weight (Female) - increased
Body Weight (Male) - decreased
Body Weight (Male) - increased
Body Weight (Z-score) - decreased
Body Weight (Z-score) - increased
Body Weight (Z-score, female) - decreased
Body Weight (Z-score, female) - increased
Body Weight (Z-score, male) - decreased
Body Weight (Z-score, male) - increased
Bone: Femur Length (AI, residual) - decreased
Bone: Femur Length (AI, residual) - increased
Bone: Femur Length (AI, residual, female) - decreased
Bone: Femur Length (AI, residual, female) - increased
Bone: Femur Length (AI, residual, male) - decreased
Bone: Femur Length (AI, residual, male) - increased
Bone: Fore Hip Distance (AI) - decreased
Bone: Fore Hip Distance (AI) - increased
Bone: Fore Hip Distance (AI, female) - decreased
Bone: Fore Hip Distance (AI, female) - increased
Bone: Fore Hip Distance (AI, male) - decreased
Bone: Fore Hip Distance (AI, male) - increased
Bone: Hind Hip Distance (AI) - decreased
Bone: Hind Hip Distance (AI) - increased
Bone: Hind Hip Distance (AI, female) - decreased
Bone: Hind Hip Distance (AI, female) - increased
Bone: Hind Hip Distance (AI, male) - decreased
Bone: Hind Hip Distance (AI, male) - increased
Bone: Hip Ratio (AI) - decreased
Bone: Hip Ratio (AI) - increased
Bone: Pelvis Length (AI, residual) - decreased
Bone: Pelvis Length (AI, residual) - increased
Bone: Pelvis Length (AI, residual, female) - decreased
Bone: Pelvis Length (AI, residual, female) - increased
Bone: Pelvis Length (AI, residual, male) - decreased
Bone: Pelvis Length (AI, residual, male) - increased
Bone: Spine Deformity (female)
Bone: Spine Deformity (male)
Bone: Tibia Length (AI, residual) - decreased
Bone: Tibia Length (AI, residual) - increased
Bone: Tibia Length (AI, residual, female) - decreased
Bone: Tibia Length (AI, residual, female) - increased
Bone: Tibia Length (AI, residual, male) - decreased
Bone: Tibia Length (AI, residual, male) - increased
cardiovascular system
CD8 response - decreased
cellular phenotype
craniofacial
CTL killing - decreased
CTL killing - increased
CTL killing dominant epitope - decreased
CTL killing dominant epitope - increased
CTL killing subdominant epitope - decreased
CTL killing subdominant epitope - increased
digestive/alimentary
dsDNA Antibody - decreased
dsDNA Antibody - increased
dsDNA induced type I IFN production - decreased
dsDNA induced type I IFN production - increased
DSS: Body Weight - decreased
DSS: Body Weight - increased
DSS: Body Weight (Day10) - decreased
DSS: Body Weight (Day10) - increased
DSS: Body Weight (Day7) - decreased
DSS: Body Weight (Day7) - increased
DSS: Body Weight (Female) - decreased
DSS: Body Weight (Female) - increased
DSS: Body Weight (Male) - decreased
DSS: Body Weight (Male) - increased
DSS: Body Weight (z-score) - decreased
DSS: Body Weight (z-score) - increased
DSS: Body Weight (z-score, female) - decreased
DSS: Body Weight (z-score, female) - increased
DSS: Body Weight (z-score, male) - decreased
DSS: Body Weight (z-score, male) - increased
DSS: resistant
DSS: resistant day 10
DSS: resistant day 7
DSS: sensitive day 10
DSS: sensitive day 7
embryogenesis
endocrine/exocrine gland
extracellular cGAMP: high response
extracellular cGAMP: low response
Eye: GCC - decreased
Eye: GCC - increased
Eye: ILM-OPL - decreased
Eye: ILM-OPL - increased
eye: micro-ophthalmia
Eye: SL-OCT BM to ILM thickness - decreased
Eye: SL-OCT BM to ILM thickness - increased
Eye: SL-OCT BM to ILM thickness (base) - decreased
Eye: SL-OCT BM to ILM thickness (base) - increased
Eye: SL-OCT BM to ILM thickness (delta) - decreased
Eye: SL-OCT BM to ILM thickness (delta) - increased
Eye: SL-OCT INL to ILM thickness - decreased
Eye: SL-OCT INL to ILM thickness - increased
Eye: SL-OCT INL to ILM thickness (base) - decreased
Eye: SL-OCT INL to ILM thickness (base) - increased
Eye: SL-OCT INL to ILM thickness (delta) - decreased
Eye: SL-OCT INL to ILM thickness (delta) - increased
Eye: SL-OCT IPL to ILM thickness - decreased
Eye: SL-OCT IPL to ILM thickness - increased
Eye: SL-OCT IPL to ILM thickness (base) - decreased
Eye: SL-OCT IPL to ILM thickness (base) - increased
Eye: SL-OCT IPL to ILM thickness (delta) - decreased
Eye: SL-OCT IPL to ILM thickness (delta) - increased
FACS: B cells - decreased
FACS: B cells - increased
FACS: B:T cells - decreased
FACS: B:T cells - increased
FACS: B1 cells - decreased
FACS: B1 cells - increased
FACS: B1a cells - decreased
FACS: B1a cells - increased
FACS: B1a cells in B1 cells - decreased
FACS: B1a cells in B1 cells - increased
FACS: B1b cells - decreased
FACS: B1b cells - increased
FACS: B1b cells in B1 cells - decreased
FACS: B1b cells in B1 cells - increased
FACS: B2 cells - decreased
FACS: B2 cells - increased
FACS: B220 MFI - decreased
FACS: B220 MFI - increased
FACS: CD11b+ DCs (gated in CD11c+ cells) - decreased
FACS: CD11b+ DCs (gated in CD11c+ cells) - increased
FACS: CD11c+ DCs - decreased
FACS: CD11c+ DCs - increased
FACS: CD4:CD8 - decreased
FACS: CD4:CD8 - increased
FACS: CD4+ T cells - decreased
FACS: CD4+ T cells - increased
FACS: CD4+ T cells in CD3+ T cells - decreased
FACS: CD4+ T cells in CD3+ T cells - increased
FACS: CD44+ CD4 MFI - decreased
FACS: CD44+ CD4 MFI - increased
FACS: CD44+ CD4 T cells - decreased
FACS: CD44+ CD4 T cells - increased
FACS: CD44+ CD8 MFI - decreased
FACS: CD44+ CD8 MFI - increased
FACS: CD44+ CD8 T cells - decreased
FACS: CD44+ CD8 T cells - increased
FACS: CD44+ T cells - decreased
FACS: CD44+ T cells - increased
FACS: CD44+ T MFI - decreased
FACS: CD44+ T MFI - increased
FACS: CD8+ T cells - decreased
FACS: CD8+ T cells - increased
FACS: CD8+ T cells in CD3+ T cells - decreased
FACS: CD8+ T cells in CD3+ T cells - increased
FACS: CD8a+ DCs (gated in CD11c+ cells) - decreased
FACS: CD8a+ DCs (gated in CD11c+ cells) - increased
FACS: central memory CD4 T cells in CD4 T cells - decreased
FACS: central memory CD4 T cells in CD4 T cells - increased
FACS: central memory CD8 T cells in CD8 T cells - decreased
FACS: central memory CD8 T cells in CD8 T cells - increased
FACS: effector memory CD4 T cells in CD4 T cells - decreased
FACS: effector memory CD4 T cells in CD4 T cells - increased
FACS: effector memory CD8 T cells in CD8 T cells - decreased
FACS: effector memory CD8 T cells in CD8 T cells - increased
FACS: effector T cells - decreased
FACS: effector T cells - increased
FACS: IgD MFI - decreased
FACS: IgD MFI - increased
FACS: IgD+ B cell percentage - decreased
FACS: IgD+ B cell percentage - increased
FACS: IgM MFI - decreased
FACS: IgM MFI - increased
FACS: IgM+ B cells - decreased
FACS: IgM+ B cells - increased
FACS: macrophages - decreased
FACS: macrophages - increased
FACS: memory T cells - decreased
FACS: memory T cells - increased
FACS: naive CD4 T cells in CD4 T cells - decreased
FACS: naive CD4 T cells in CD4 T cells - increased
FACS: naive CD8 T cells in CD8 T cells - decreased
FACS: naive CD8 T cells in CD8 T cells - increased
FACS: naive T cells - decreased
FACS: naive T cells - increased
FACS: neutrophils - decreased
FACS: neutrophils - increased
FACS: NK cells - decreased
FACS: NK cells - increased
FACS: NK1.1+ T cells - decreased
FACS: NK1.1+ T cells - increased
FACS: NKT cells (tet) - decreased
FACS: NKT cells (tet) - increased
FACS: pDCs - decreased
FACS: pDCs - increased
FACS: T cells - decreased
FACS: T cells - increased
growth/size
hearing/vestibular/ear
hematopoietic competition - disadvantage
hematopoietic system
homeostasis/metabolism
IgA response to 2nd OVA/Alum Challenge (day 7) - decreased
IgA response to 2nd OVA/Alum Challenge (day 7) - increased
IgE response to a Cysteine Protease (Papain) - decreased
IgE response to a Cysteine Protease (Papain) - increased
IgG1 response to a Cysteine Protease (Papain) - decreased
IgG1 response to a Cysteine Protease (Papain) - increased
immune system
impaired response to dsDNA- type I IFN production by macrophages
inflammatory bowel disease phenotype
influenza proliferation in macrophages - decreased
influenza proliferation in macrophages - increased
influenza resistance
iron deficiency
iron excess
LCMV clone 13 resistance
lethality-embryonic/perinatal
lethality-postnatal
life span-post-weaning/aging
limbs/digits/tail phenotype
liver/biliary system
LPS Cachexia: Body Weight (day 0) - decreased
LPS Cachexia: Body Weight (day 0) - increased
LPS Cachexia: Body Weight (day 0, z-score) - decreased
LPS Cachexia: Body Weight (day 0, z-score) - increased
LPS Cachexia: Body Weight (day 1) - decreased
LPS Cachexia: Body Weight (day 1) - increased
LPS Cachexia: Body Weight (day 14) - decreased
LPS Cachexia: Body Weight (day 14) - increased
LPS Cachexia: Body Weight (day 2) - decreased
LPS Cachexia: Body Weight (day 2) - increased
LPS Cachexia: Body Weight Change (day 1, g) - decreased
LPS Cachexia: Body Weight Change (day 1, g) - increased
LPS Cachexia: Body Weight Change (day 1, ratio) - decreased
LPS Cachexia: Body Weight Change (day 1, ratio) - increased
LPS Cachexia: Body Weight Change (day 14, g) - decreased
LPS Cachexia: Body Weight Change (day 14, g) - increased
LPS Cachexia: Body Weight Change (day 14, ratio) - decreased
LPS Cachexia: Body Weight Change (day 14, ratio) - increased
LPS Cachexia: Body Weight Change (day 2, g) - decreased
LPS Cachexia: Body Weight Change (day 2, g) - increased
LPS Cachexia: Body Weight Change (day 2, ratio) - decreased
LPS Cachexia: Body Weight Change (day 2, ratio) - increased
LPS Hypersensitivity - decreased
LPS Hypersensitivity - increased
LPS-induced Necroptosis - decreased
LPS-induced Necroptosis - increased
Macrophage necroptosis: high
Macrophage necroptosis: low
MC38: tumor body weight change (%) - decreased
MC38: tumor body weight change (%) - increased
MC38: tumor body weight change (%, female) - decreased
MC38: tumor body weight change (%, female) - increased
MC38: tumor body weight change (%, male) - decreased
MC38: tumor body weight change (%, male) - increased
MC38: tumor body weight change (g) - decreased
MC38: tumor body weight change (g) - increased
MC38: tumor body weight change (g, female) - decreased
MC38: tumor body weight change (g, female) - increased
MC38: tumor body weight change (g, male) - decreased
MC38: tumor body weight change (g, male) - increased
MC38: tumor volume (day 22) - decreased
MC38: tumor volume (day 22) - increased
MC38: tumor volume (day 22, early sac sick or found dead, IM injection, dermatitis, trimmed) - decreased
MC38: tumor volume (day 22, early sac sick or found dead, IM injection, dermatitis, trimmed) - increased
MCMV proliferation in macrophages - decreased
MCMV proliferation in macrophages - increased
MCMV resistance
MCMV susceptibility
MTT dsDNA PECs - decreased
MTT dsDNA PECs - increased
MTT Value of PECs - decreased
MTT Value of PECs - increased
muscle
NALP3 inflammasome signaling defect
nervous system
NK cell response - decreased
NK killing - decreased
NK killing - increased
Nlrc4 inflammasome: high response
Nlrc4 inflammasome: low response
NLRP3 inflammasome: high response
NLRP3 inflammasome: low response
no phenotypic analysis
normal phenotype
other phenotype
OVA-specific IgE - decreased
OVA-specific IgE - increased
OVA-specific IgE after 2nd OVA/Alum - decreased
OVA-specific IgE after 2nd OVA/Alum - increased
Peritoneal exudates B1a cell % - decreased
Peritoneal exudates B1a cell % - increased
Peritoneal exudates B1a cell numbers - decreased
Peritoneal exudates B1a cell numbers - increased
Peritoneal exudates B1b cell % - decreased
Peritoneal exudates B1b cell % - increased
Peritoneal exudates B1b cell numbers - decreased
Peritoneal exudates B1b cell numbers - increased
Peritoneal exudates macrophage % - decreased
Peritoneal exudates macrophage % - increased
Peritoneal exudates macrophage numbers - decreased
Peritoneal exudates macrophage numbers - increased
Peritoneal exudates neutrophil % - decreased
Peritoneal exudates neutrophil % - increased
Peritoneal exudates neutrophil numbers - decreased
Peritoneal exudates neutrophil numbers - increased
phagocytosis in PECs - decreased
phagocytosis in PECs - increased
pigmentation
polycythemia
post-MCMV: FACS B cells - decreased
post-MCMV: FACS B cells - increased
post-MCMV: FACS B:T cells - decreased
post-MCMV: FACS B:T cells - increased
post-MCMV: FACS B1 cells - decreased
post-MCMV: FACS B1 cells - increased
post-MCMV: FACS B1a cells - decreased
post-MCMV: FACS B1a cells - increased
post-MCMV: FACS B1a cells in B1 cells - decreased
post-MCMV: FACS B1a cells in B1 cells - increased
post-MCMV: FACS B1b cells - decreased
post-MCMV: FACS B1b cells - increased
post-MCMV: FACS B1b cells in B1 cells - decreased
post-MCMV: FACS B1b cells in B1 cells - increased
post-MCMV: FACS B2 cells - decreased
post-MCMV: FACS B2 cells - increased
post-MCMV: FACS B220 MFI - decreased
post-MCMV: FACS B220 MFI - increased
post-MCMV: FACS CD11b+ DCs (gated in CD11c+ cells) - decreased
post-MCMV: FACS CD11b+ DCs (gated in CD11c+ cells) - increased
post-MCMV: FACS CD11c+ DCs - decreased
post-MCMV: FACS CD11c+ DCs - increased
post-MCMV: FACS CD4:CD8 - decreased
post-MCMV: FACS CD4:CD8 - increased
post-MCMV: FACS CD4+ T cells - decreased
post-MCMV: FACS CD4+ T cells - increased
post-MCMV: FACS CD4+ T cells in CD3+ T cells - decreased
post-MCMV: FACS CD4+ T cells in CD3+ T cells - increased
post-MCMV: FACS CD44+ CD4 MFI - decreased
post-MCMV: FACS CD44+ CD4 MFI - increased
post-MCMV: FACS CD44+ CD4 T cells - decreased
post-MCMV: FACS CD44+ CD4 T cells - increased
post-MCMV: FACS CD44+ CD8 MFI - decreased
post-MCMV: FACS CD44+ CD8 MFI - increased
post-MCMV: FACS CD44+ CD8 T cells - decreased
post-MCMV: FACS CD44+ CD8 T cells - increased
post-MCMV: FACS CD44+ T cells - decreased
post-MCMV: FACS CD44+ T cells - increased
post-MCMV: FACS CD44+ T MFI - decreased
post-MCMV: FACS CD44+ T MFI - increased
post-MCMV: FACS CD8+ T cells - decreased
post-MCMV: FACS CD8+ T cells - increased
post-MCMV: FACS CD8+ T cells in CD3+ T cells - decreased
post-MCMV: FACS CD8+ T cells in CD3+ T cells - increased
post-MCMV: FACS CD8a+ DCs (gated in CD11c+ cells) - decreased
post-MCMV: FACS CD8a+ DCs (gated in CD11c+ cells) - increased
post-MCMV: FACS central memory CD4 T cells in CD4 T cells - decreased
post-MCMV: FACS central memory CD4 T cells in CD4 T cells - increased
post-MCMV: FACS central memory CD8 T cells in CD8 T cells - decreased
post-MCMV: FACS central memory CD8 T cells in CD8 T cells - increased
post-MCMV: FACS effector memory CD4 T cells in CD4 T cells - decreased
post-MCMV: FACS effector memory CD4 T cells in CD4 T cells - increased
post-MCMV: FACS effector memory CD8 T cells in CD8 T cells - decreased
post-MCMV: FACS effector memory CD8 T cells in CD8 T cells - increased
post-MCMV: FACS effector T cells - decreased
post-MCMV: FACS effector T cells - increased
post-MCMV: FACS IgD MFI - decreased
post-MCMV: FACS IgD MFI - increased
post-MCMV: FACS IgD+ B cell percentage - decreased
post-MCMV: FACS IgD+ B cell percentage - increased
post-MCMV: FACS IgM MFI - decreased
post-MCMV: FACS IgM MFI - increased
post-MCMV: FACS IgM+ B cells - decreased
post-MCMV: FACS IgM+ B cells - increased
post-MCMV: FACS macrophages - decreased
post-MCMV: FACS macrophages - increased
post-MCMV: FACS memory T cells - decreased
post-MCMV: FACS memory T cells - increased
post-MCMV: FACS naive CD4 T cells in CD4 T cells - decreased
post-MCMV: FACS naive CD4 T cells in CD4 T cells - increased
post-MCMV: FACS naive CD8 T cells in CD8 T cells - decreased
post-MCMV: FACS naive CD8 T cells in CD8 T cells - increased
post-MCMV: FACS naive T cells - decreased
post-MCMV: FACS naive T cells - increased
post-MCMV: FACS neutrophils - decreased
post-MCMV: FACS neutrophils - increased
post-MCMV: FACS NK cells - decreased
post-MCMV: FACS NK cells - increased
post-MCMV: FACS NK T cells - decreased
post-MCMV: FACS NK T cells - increased
post-MCMV: FACS NKT cells (tet) - decreased
post-MCMV: FACS NKT cells (tet) - increased
post-MCMV: FACS pDCs - decreased
post-MCMV: FACS pDCs - increased
post-MCMV: FACS T cells - decreased
post-MCMV: FACS T cells - increased
ratio of OVA-specific IgE over the total IgE - decreased
ratio of OVA-specific IgE over the total IgE - increased
renal/urinary system
reproductive system
resistance to B10-F16 melanoma - decreased
resistance to B10-F16 melanoma - increased
respiratory system
response to injected CpG DNA - decreased
RVFV proliferation in macrophages - decreased
RVFV proliferation in macrophages - increased
RVFV susceptibility
secretory SlgA after 2nd OVA/Alum Challenge (day 7) - decreased
secretory SlgA after 2nd OVA/Alum Challenge (day 7) - increased
skeleton phenotype
skin/coat/nails
taste/olfaction
T-dependent humoral response defect- decreased antibody response to OVA+ alum immunization
T-dependent humoral response defect- decreased antibody response to rSFV
T-dependent humoral response defect- increased antibody response to OVA+ alum immunization
T-dependent humoral response defect- increased antibody response to rSFV
T-independent B cell response defect- decreased TNP-specific IgM to TNP-Ficoll immunization
T-independent B cell response defect- increased TNP-specific IgM to TNP-Ficoll immunization
TLR signaling defect: hypersensitivity to CpG + IFNg
TLR signaling defect: hypersensitivity to LPS
TLR signaling defect: hypersensitivity to MALP2
TLR signaling defect: hypersensitivity to PAM3CSK4
TLR signaling defect: hypersensitivity to poly I:C
TLR signaling defect: hypersensitivity to poly I:C + IFNg
TLR signaling defect: hypersensitivity to R848
TLR signaling defect: hyposensitivity to CpG + IFNg
TLR signaling defect: hyposensitivity to LPS
TLR signaling defect: hyposensitivity to MALP2
TLR signaling defect: hyposensitivity to PAM3CSK4
TLR signaling defect: hyposensitivity to poly I:C
TLR signaling defect: hyposensitivity to poly I:C + IFNg
TLR signaling defect: hyposensitivity to R848
TLR signaling defect: TNF production by macrophages
total IgE after 2nd OVA/Alum - decreased
total IgE after 2nd OVA/Alum - increased
Total IgE After 2nd OVA/Alum Challenge (day 7) - decreased
Total IgE After 2nd OVA/Alum Challenge (day 7) - increased
total IgE level - decreased
total IgE level - increased
touch/vibrissae
tumorigenesis
vision/eye