Mutation Statistics

^*Note: the numbers of strains with the indicated mutation types, DNA base changes,
or amino acid changes include some strains not shown on the Mutations lists.

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Phenotypic Mutation Types Mutation Type Number* makesense 15 missense 4077 nonsense 683 start codon destroyed 33 start gained 4 synonymous 1 splice acceptor site 17 splice donor site 30 critical splice acceptor site 71 critical splice donor site 403 splice site 241 large deletion 2 large insertion 0 rearrangement 0 small deletion 4 small insertion 0 exon 0 frame shift 35 intragenic 0 intron 70 utr 3 prime 7 utr 5 prime 5 Total: 5698	Incidental Mutation Types Mutation Type Number* makesense 1480 missense 511700 nonsense 25768 start codon destroyed 2024 start gained 2028 synonymous 113 splice acceptor site 0 splice donor site 0 critical splice acceptor site 3478 critical splice donor site 14211 splice site 26835 large deletion 0 large insertion 0 rearrangement 0 small deletion 1345 small insertion 1866 exon 2010 frame shift 2396 intragenic 0 intron 6019 utr 3 prime 1456 utr 5 prime 720 unclassified 10014 Total: 613463
Phenotypic Mutation DNA Base Changes (assembly) DNA Base Change Number* A ⇒ C 128 A ⇒ G 1060 A ⇒ T 782 C ⇒ A 264 C ⇒ G 21 C ⇒ T 445 G ⇒ A 444 G ⇒ C 22 G ⇒ T 280 T ⇒ A 954 T ⇒ C 1134 T ⇒ G 157 Total: 5691	Incidental Mutation DNA Base Changes (assembly) DNA Base Change Number* A ⇒ C 15282 A ⇒ G 123106 A ⇒ T 82168 C ⇒ A 28979 C ⇒ G 3524 C ⇒ T 49128 G ⇒ A 48422 G ⇒ C 3570 G ⇒ T 28354 T ⇒ A 83306 T ⇒ C 123877 T ⇒ G 15478 Total: 605194
Phenotypic Mutation Amino Acid Changes Amino Acid Change   From To Number* Alanine Aspartic acid 9 Alanine Glutamic Acid 14 Alanine Glycine 4 Alanine Proline 2 Alanine Serine 13 Alanine Threonine 13 Alanine Valine 27 Arginine Cysteine 39 Arginine Glutamine 29 Arginine Glycine 23 Arginine Histidine 38 Arginine Isoleucine 0 Arginine Leucine 40 Arginine Lysine 1 Arginine Methionine 0 Arginine Proline 3 Arginine Serine 16 Arginine Threonine 0 Arginine Tryptophan 24 Arginine Stop codon 88 Asparagine Aspartic acid 30 Asparagine Histidine 1 Asparagine Isoleucine 26 Asparagine Lysine 61 Asparagine Serine 59 Asparagine Threonine 7 Asparagine Tyrosine 22 Aspartic acid Alanine 13 Aspartic acid Asparagine 10 Aspartic acid Glutamic Acid 75 Aspartic acid Glycine 197 Aspartic acid Histidine 1 Aspartic acid Tyrosine 6 Aspartic acid Valine 64 Cysteine Arginine 46 Cysteine Glycine 7 Cysteine Phenylalanine 24 Cysteine Serine 47 Cysteine Tryptophan 3 Cysteine Tyrosine 27 Cysteine Stop codon 84 Glutamic Acid Alanine 3 Glutamic Acid Aspartic acid 12 Glutamic Acid Glutamine 1 Glutamic Acid Glycine 122 Glutamic Acid Lysine 18 Glutamic Acid Valine 14 Glutamic Acid Stop codon 44 Glutamine Arginine 14 Glutamine Glutamic Acid 1 Glutamine Histidine 9 Glutamine Leucine 22 Glutamine Lysine 22 Glutamine Proline 4 Glutamine Stop codon 118 Glycine Alanine 2 Glycine Arginine 16 Glycine Aspartic acid 26 Glycine Cysteine 9 Glycine Glutamic Acid 5 Glycine Serine 13 Glycine Tryptophan 8 Glycine Valine 10 Glycine Stop codon 12 Histidine Arginine 43 Histidine Asparagine 16 Histidine Aspartic acid 2 Histidine Glutamine 37 Histidine Leucine 33 Histidine Proline 9 Histidine Tyrosine 8 Isoleucine Arginine 3 Isoleucine Asparagine 107 Isoleucine Leucine 21 Isoleucine Lysine 26 Isoleucine Methionine 9 Isoleucine Phenylalanine 56 Isoleucine Serine 11 Isoleucine Threonine 106 Isoleucine Valine 43 Leucine Arginine 23 Leucine Glutamine 58 Leucine Histidine 11 Leucine Isoleucine 4 Leucine Methionine 6 Leucine Phenylalanine 14 Leucine Proline 149 Leucine Serine 19 Leucine Tryptophan 2 Leucine Valine 5 Leucine Stop codon 48 Lysine Arginine 13 Lysine Asparagine 15 Lysine Glutamic Acid 49 Lysine Glutamine 3 Lysine Isoleucine 0 Lysine Methionine 4 Lysine Threonine 4 Lysine Stop codon 72 Methionine Arginine 16 Methionine Isoleucine 17 Methionine Leucine 27 Methionine Lysine 89 Methionine Threonine 27 Methionine Valine 30 Phenylalanine Cysteine 4 Phenylalanine Isoleucine 27 Phenylalanine Leucine 72 Phenylalanine Serine 57 Phenylalanine Tyrosine 6 Phenylalanine Valine 11 Proline Alanine 0 Proline Arginine 0 Proline Glutamine 6 Proline Histidine 0 Proline Leucine 19 Proline Serine 18 Proline Threonine 7 Serine Alanine 8 Serine Arginine 23 Serine Asparagine 11 Serine Cysteine 10 Serine Glycine 29 Serine Isoleucine 3 Serine Leucine 9 Serine Phenylalanine 3 Serine Proline 177 Serine Threonine 40 Serine Tryptophan 0 Serine Tyrosine 3 Serine Stop codon 21 Threonine Alanine 108 Threonine Arginine 1 Threonine Asparagine 4 Threonine Isoleucine 60 Threonine Lysine 26 Threonine Methionine 16 Threonine Proline 10 Threonine Serine 36 Tryptophan Arginine 55 Tryptophan Cysteine 1 Tryptophan Glycine 1 Tryptophan Leucine 4 Tryptophan Serine 0 Tryptophan Stop codon 26 Tyrosine Asparagine 40 Tyrosine Aspartic acid 6 Tyrosine Cysteine 116 Tyrosine Histidine 89 Tyrosine Phenylalanine 21 Tyrosine Serine 3 Tyrosine Stop codon 165 Valine Alanine 204 Valine Aspartic acid 51 Valine Glutamic Acid 95 Valine Glycine 21 Valine Isoleucine 42 Valine Leucine 19 Valine Methionine 42 Valine Phenylalanine 18 Stop codon Arginine 1 Stop codon Cysteine 2 Stop codon Glutamic Acid 0 Stop codon Glutamine 5 Stop codon Glycine 1 Stop codon Leucine 3 Stop codon Lysine 1 Stop codon Serine 0 Stop codon Tryptophan 2 Stop codon Tyrosine 0 4792 changes of 158 types	Incidental Mutation Amino Acid Changes Amino Acid Change   From To Number* Alanine Aspartic acid 901 Alanine Glutamic Acid 1713 Alanine Glycine 332 Alanine Proline 429 Alanine Serine 2959 Alanine Threonine 4296 Alanine Valine 4302 Arginine Cysteine 3655 Arginine Glutamine 3541 Arginine Glycine 3503 Arginine Histidine 4265 Arginine Isoleucine 134 Arginine Leucine 3699 Arginine Lysine 553 Arginine Methionine 167 Arginine Proline 370 Arginine Serine 2898 Arginine Threonine 65 Arginine Tryptophan 2571 Arginine Stop codon 3304 Asparagine Aspartic acid 3576 Asparagine Histidine 287 Asparagine Isoleucine 3207 Asparagine Lysine 8200 Asparagine Serine 9581 Asparagine Threonine 727 Asparagine Tyrosine 1769 Aspartic acid Alanine 1857 Aspartic acid Asparagine 2638 Aspartic acid Glutamic Acid 10996 Aspartic acid Glycine 22148 Aspartic acid Histidine 198 Aspartic acid Tyrosine 1139 Aspartic acid Valine 6742 Cysteine Arginine 2775 Cysteine Glycine 608 Cysteine Phenylalanine 1804 Cysteine Serine 4684 Cysteine Tryptophan 352 Cysteine Tyrosine 2593 Cysteine Stop codon 3241 Glutamic Acid Alanine 827 Glutamic Acid Aspartic acid 2736 Glutamic Acid Glutamine 260 Glutamic Acid Glycine 15156 Glutamic Acid Lysine 3521 Glutamic Acid Valine 2274 Glutamic Acid Stop codon 1884 Glutamine Arginine 2352 Glutamine Glutamic Acid 195 Glutamine Histidine 937 Glutamine Leucine 4057 Glutamine Lysine 2968 Glutamine Proline 666 Glutamine Stop codon 3943 Glycine Alanine 330 Glycine Arginine 2024 Glycine Aspartic acid 2844 Glycine Cysteine 1097 Glycine Glutamic Acid 1001 Glycine Serine 1628 Glycine Tryptophan 765 Glycine Valine 1410 Glycine Stop codon 511 Histidine Arginine 4986 Histidine Asparagine 1410 Histidine Aspartic acid 111 Histidine Glutamine 4994 Histidine Leucine 4959 Histidine Proline 599 Histidine Tyrosine 1808 Isoleucine Arginine 302 Isoleucine Asparagine 8480 Isoleucine Leucine 3298 Isoleucine Lysine 2052 Isoleucine Methionine 1980 Isoleucine Phenylalanine 9279 Isoleucine Serine 1272 Isoleucine Threonine 11590 Isoleucine Valine 10187 Leucine Arginine 1789 Leucine Glutamine 5057 Leucine Histidine 1399 Leucine Isoleucine 967 Leucine Methionine 752 Leucine Phenylalanine 3127 Leucine Proline 10760 Leucine Serine 1317 Leucine Tryptophan 146 Leucine Valine 649 Leucine Stop codon 2062 Lysine Arginine 3555 Lysine Asparagine 2781 Lysine Glutamic Acid 5556 Lysine Glutamine 437 Lysine Isoleucine 325 Lysine Methionine 725 Lysine Threonine 625 Lysine Stop codon 2604 Methionine Arginine 960 Methionine Isoleucine 2448 Methionine Leucine 5003 Methionine Lysine 8489 Methionine Threonine 3320 Methionine Valine 3656 Phenylalanine Cysteine 351 Phenylalanine Isoleucine 3045 Phenylalanine Leucine 8995 Phenylalanine Serine 4980 Phenylalanine Tyrosine 1297 Phenylalanine Valine 896 Proline Alanine 312 Proline Arginine 279 Proline Glutamine 1510 Proline Histidine 382 Proline Leucine 3118 Proline Serine 3921 Proline Threonine 1188 Serine Alanine 2048 Serine Arginine 4058 Serine Asparagine 1735 Serine Cysteine 1437 Serine Glycine 4114 Serine Isoleucine 628 Serine Leucine 1642 Serine Phenylalanine 1082 Serine Proline 19300 Serine Threonine 6459 Serine Tryptophan 34 Serine Tyrosine 365 Serine Stop codon 922 Threonine Alanine 21880 Threonine Arginine 161 Threonine Asparagine 1076 Threonine Isoleucine 8107 Threonine Lysine 3132 Threonine Methionine 3531 Threonine Proline 1345 Threonine Serine 7054 Tryptophan Arginine 3319 Tryptophan Cysteine 254 Tryptophan Glycine 225 Tryptophan Leucine 641 Tryptophan Serine 47 Tryptophan Stop codon 1152 Tyrosine Asparagine 3395 Tyrosine Aspartic acid 469 Tyrosine Cysteine 10897 Tyrosine Histidine 8314 Tyrosine Phenylalanine 3938 Tyrosine Serine 485 Tyrosine Stop codon 5896 Valine Alanine 26459 Valine Aspartic acid 4169 Valine Glutamic Acid 7032 Valine Glycine 2449 Valine Isoleucine 7342 Valine Leucine 3229 Valine Methionine 5135 Valine Phenylalanine 2013 Stop codon Arginine 316 Stop codon Cysteine 87 Stop codon Glutamic Acid 22 Stop codon Glutamine 301 Stop codon Glycine 48 Stop codon Leucine 77 Stop codon Lysine 98 Stop codon Serine 13 Stop codon Tryptophan 415 Stop codon Tyrosine 26 540628 changes of 170 types

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