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Incidental Mutations

82 incidental mutations are currently displayed, and affect 82 genes.

16 are Possibly Damaging.

30 are Probably Damaging.

26 are Probably Benign.

9 are Probably Null.

4 create premature stop codons.

2 are critical splice junction mutations.

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Mutations in Coding Regions/Splice Sites Identified by Next-Gen Sequencing

[records 1 to 82 of 82] 10 25 50 100 500 1000 per page Full List
	ID	Source UTSW APN	Gene	E-score	Stock #	Gen G0 G0' G1 G2 G3 G3R F1 F2 F3 C0 C1 C2 C3 D1 HES IPS A3	Quality -	Vld Y N ?	Strain	Chr 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 X Y	Position	Mutation A R N D C E Q G H I L K M F P S T W Y V * A R N D C E Q G H I L K M F P S T W Y V *	Ref A C G T -	Var A C G T -	Type makesense missense nonsense start codon destroyed start gained synonymous splice acceptor site splice donor site critical splice acceptor site critical splice donor site splice site large deletion large insertion rearrangement small deletion small insertion exon frame shift intragenic intron utr 3 prime utr 5 prime unclassified	Exon Dist	Zygosity Homo Het Hemi Null	Predicted Effect unknown probably benign probably null possibly damaging probably damaging noncoding transcript silent not run no transcript	PPH Score -	Meta Score	MGI Phenotype available none listed	Posted
1	537769		Adcy8	0.144	R6823	G1	225.01	N		15	64754886		T	G	critical splice acceptor site		Het	probably null			phenotype	10/18/2018
2	537762		Adgrv1	0.000	R6823	G1	225.01	N		13	81557081	F1537L	A	G	missense		Het	probably damaging	1.000		phenotype	10/18/2018
3	537763		Aggf1	0.615	R6823	G1	225.01	N		13	95364723	S384G	T	C	missense		Het	probably benign	0.112		phenotype	10/18/2018
4	537766		Anxa8	0.083	R6823	G1	225.01	N		14	34094765	D204V	A	T	missense		Het	possibly damaging	0.878		phenotype	10/18/2018
5	537717		Asap3	0.166	R6823	G1	225.01	N		4	136227572	E71V	A	T	missense		Het	possibly damaging	0.950		phenotype	10/18/2018
6	537771		BC024139	0.060	R6823	G1	225.01	N		15	76119746	*773W	T	C	makesense		Het	probably null				10/18/2018
7	537743		Bckdhb	1.000	R6823	G1	225.01	N		9	83953761	V106A	T	C	missense		Het	possibly damaging	0.761		phenotype	10/18/2018
8	537710		Cep250	0.720	R6823	G1	225.01	N		2	155981459	D1010G	A	G	missense		Het	probably benign	0.021		phenotype	10/18/2018
9	537773		Chrd	1.000	R6823	G1	225.01	N		16	20734736	L243Q	T	A	missense		Het	probably damaging	1.000		phenotype	10/18/2018
10	537742		Cib2	0.081	R6823	G1	225.01	N		9	54549891	L30I	G	T	missense		Het	possibly damaging	0.894		phenotype	10/18/2018
11	537782		Cpsf7	0.575	R6823	G1	225.01	N		19	10532884	L113*	T	A	nonsense		Het	probably null			phenotype	10/18/2018
12	537708		Cubn	1.000	R6823	G1	225.01	N		2	13445029	I895L	T	A	missense		Het	probably benign	0.206		phenotype	10/18/2018
13	537711		Cyp24a1	0.184	R6823	G1	225.01	N		2	170487979	R351I	C	A	missense		Het	probably benign	0.117		phenotype	10/18/2018
14	537727		Cyp2a12	0.025	R6823	G1	225.01	N		7	27034156	D320V	A	T	missense		Het	possibly damaging	0.774			10/18/2018
15	537760		Dact1	1.000	R6823	G1	225.01	N		12	71317939	P498R	C	G	missense		Het	probably benign	0.098		phenotype	10/18/2018
16	537778		Diaph1	0.000	R6823	G1	225.01	N		18	37876383		T	A	intron	13315 bp	Het	probably null			phenotype	10/18/2018
17	537704		Dnah7a	0.285	R6823	G1	225.01	N		1	53456704	I3198N	A	T	missense		Het	probably benign	0.000			10/18/2018
18	537774		Dopey2	0.346	R6823	G1	225.01	N		16	93755485	I271F	A	T	missense		Het	possibly damaging	0.754			10/18/2018
19	537715		Erich3	0.217	R6823	G1	225.01	N		3	154727437	F349L	C	A	missense		Het	probably damaging	1.000			10/18/2018
20	537729		Fam187b	0.070	R6823	G1	225.01	N		7	30989290	V358L	G	C	missense		Het	probably benign	0.014			10/18/2018
21	537712		Fat4	1.000	R6823	G1	225.01	N		3	38983939	H3913Q	T	A	missense		Het	probably benign	0.055		phenotype	10/18/2018
22	537713		Fbxw7	1.000	R6823	G1	225.01	N		3	84958627	E118D	G	C	missense		Het	probably benign	0.326		phenotype	10/18/2018
23	537779		Fgf1	0.000	R6823	G1	225.01	N		18	38847108	I71T	A	G	missense		Het	probably damaging	0.998		phenotype	10/18/2018
24	537720		Fryl	0.878	R6823	G1	225.01	N		5	73065217	I2007K	A	T	missense		Het	probably damaging	0.988		phenotype	10/18/2018
25	537740		Galnt2	0.224	R6823	G1	225.01	N		8	124324011	P130A	C	G	missense		Het	probably benign	0.000		phenotype	10/18/2018
26	537724		H1fx	0.228	R6823	G1	225.01	N		6	87981302	R19C	G	A	missense		Het	probably damaging	0.988		phenotype	10/18/2018
27	537750		Hmga2	0.480	R6823	G1	225.01	N		10	120476024	S14A	A	C	missense		Het	possibly damaging	0.875		phenotype	10/18/2018
28	537758		Hoxb4	0.719	R6823	G1	221.01	N		11	96318654		C	T	unclassified		Het	probably benign			phenotype	10/18/2018
29	537767		Hr	0.000	R6823	G1	225.01	N		14	70565374	I756F	A	T	missense		Het	probably damaging	0.981		phenotype	10/18/2018
30	537781		Hrasls5	0.047	R6823	G1	225.01	N		19	7639496		A	T	unclassified		Het	probably benign				10/18/2018
31	537776		Hspa1b	0.278	R6823	G1	225.01	N		17	34958185	S275T	A	T	missense		Het	probably benign	0.017		phenotype	10/18/2018
32	537716		Ikbkap	1.000	R6823	G1	225.01	N		4	56787939	Y331H	A	G	missense		Het	probably damaging	1.000		phenotype	10/18/2018
33	537707		Kcnh1	0.112	R6823	G1	225.01	N		1	192505289	*99R	T	C	makesense		Het	probably null			phenotype	10/18/2018
34	537721		Kit	0.871	R6823	G1	225.01	N		5	75652649	L864I	C	A	missense		Het	probably benign	0.008		phenotype	10/18/2018
35	537731		Klk14	0.167	R6823	G1	225.01	N		7	43694456	K196*	A	T	nonsense		Het	probably null			phenotype	10/18/2018
36	537705		Lmod1	0.200	R6823	G1	225.01	N		1	135325167	N53S	A	G	missense		Het	probably damaging	0.979		phenotype	10/18/2018
37	537754		Myh13	0.339	R6823	G1	225.01	N		11	67356158	M1235T	T	C	missense		Het	probably benign	0.000			10/18/2018
38	537703		Neurl3	0.038	R6823	G1	225.01	N		1	36268704	K175*	T	A	nonsense		Het	probably null				10/18/2018
39	537755		Nlgn2	0.000	R6823	G1	225.01	N		11	69825924	K597M	T	A	missense		Het	probably damaging	1.000		phenotype	10/18/2018
40	537709		Npdc1	0.000	R6823	G1	225.01	N		2	25409109	M306T	T	C	missense		Het	probably damaging	0.999		phenotype	10/18/2018
41	537753		Obscn	0.731	R6823	G1	225.01	N		11	59067943		C	T	critical splice donor site	1 bp	Het	probably null			phenotype	10/18/2018
42	537756		Olfr404-ps1		R6823	G1	155.01	N		11	74239696	L44P	T	C	missense		Het	probably damaging	1.000			10/18/2018
43	537732		Olfr553	0.191	R6823	G1	225.01	N		7	102614486	L168F	G	A	missense		Het	probably damaging	0.989		phenotype	10/18/2018
44	537741		Olfr913	0.040	R6823	G1	225.01	N		9	38594905	I228T	T	C	missense		Het	possibly damaging	0.893		phenotype	10/18/2018
45	537765		Pbrm1	1.000	R6823	G1	225.01	N		14	31084790	Y1042F	A	T	missense		Het	probably damaging	1.000		phenotype	10/18/2018
46	537718		Pclo	0.000	R6823	G1	225.01	N		5	14677907		T	A	unclassified		Het	probably benign			phenotype	10/18/2018
47	540726		Peg10	1.000	R6823	G1	204.47	N		6	4756431		CATCAGGATCCCCATCAGGATGCACATCAGGATCCACATCAGGATGCACATCAGGATC	CATC			Het				phenotype	11/16/2018
48	537757		Phf12	0.643	R6823	G1	225.01	N		11	78022511	Q430*	C	T	nonsense		Het	probably null				10/18/2018
49	537728		Pld3	0.057	R6823	G1	225.01	N		7	27535897	R302H	C	T	missense		Het	probably damaging	1.000		phenotype	10/18/2018
50	537725		Plekha5	0.277	R6823	G1	225.01	N		6	140525858	S112P	T	C	missense		Het	probably benign	0.158			10/18/2018
51	537737		Pmfbp1	0.138	R6823	G1	225.01	N		8	109530307	S548T	T	A	missense		Het	possibly damaging	0.922			10/18/2018
52	537746		Ppa1	1.000	R6823	G1	225.01	N		10	61667603	I220F	A	T	missense		Het	probably damaging	0.998		phenotype	10/18/2018
53	537745		Ppp2r3d	0.499	R6823	G1	225.01	N		9	124439078		A	G	unclassified		Het	probably benign				10/18/2018
54	537780		Psmg2	0.912	R6823	G1	225.01	N		18	67648857	E164D	A	T	missense		Het	possibly damaging	0.633			10/18/2018
55	537764		Rarb	0.000	R6823	G1	225.01	N		14	16443824	R155G	T	C	missense		Het	probably damaging	0.998		phenotype	10/18/2018
56	537751		Rnf215	0.104	R6823	G1	225.01	N		11	4136609	L162S	T	C	missense		Het	probably damaging	1.000			10/18/2018
57	540727		Rsf1	0.559	R6823	G1	217.47	N		7	97579906		GGCG	GGCGACGGCCGCG	unclassified		Het	probably benign			phenotype	11/16/2018
58	537747		Rtkn2	0.227	R6823	G1	225.01	N		10	68026632	V330M	G	A	missense		Het	probably damaging	0.960			10/18/2018
59	537714		Slc16a4	0.217	R6823	G1	225.01	N		3	107311498	I472F	A	T	missense		Het	probably benign	0.023			10/18/2018
60	537744		Snx14	1.000	R6823	G1	225.01	N		9	88394382	N617D	T	C	missense		Het	possibly damaging	0.903		phenotype	10/18/2018
61	537739		Spire2	0.138	R6823	G1	225.01	N		8	123356727	V150A	T	C	missense		Het	probably damaging	1.000			10/18/2018
62	537752		Sptbn1	1.000	R6823	G1	225.01	N		11	30114787	R1904M	C	A	missense		Het	probably damaging	1.000		phenotype	10/18/2018
63	537733		Swap70	0.357	R6823	G1	225.01	N		7	110281303	E575G	A	G	missense		Het	possibly damaging	0.750		phenotype	10/18/2018
64	537723		Tbxas1	0.047	R6823	G1	225.01	N		6	38919153	M1L	A	T	start codon destroyed		Het	possibly damaging	0.945		phenotype	10/18/2018
65	537735		Tenm3	0.312	R6823	G1	225.01	N		8	48256837	V1688D	A	T	missense		Het	probably damaging	0.988		phenotype	10/18/2018
66	537722		Tgfbr3	1.000	R6823	G1	225.01	N		5	107149914	S207T	A	T	missense		Het	probably damaging	0.998		phenotype	10/18/2018
67	537734		Timm44	0.975	R6823	G1	225.01	N		8	4267282	F248L	A	G	missense		Het	probably damaging	1.000		phenotype	10/18/2018
68	537736		Tmem161a	0.174	R6823	G1	225.01	N		8	70181199	L170P	T	C	missense		Het	probably damaging	1.000			10/18/2018
69	537706		Tmem63a	0.173	R6823	G1	225.01	N		1	180960470	Y263F	A	T	missense		Het	possibly damaging	0.600			10/18/2018
70	537777		Tnfsf9	0.183	R6823	G1	225.01	N		17	57105513	L28I	C	A	missense		Het	probably benign	0.002		phenotype	10/18/2018
71	537749		Tph2	0.332	R6823	G1	225.01	N		10	115174106	N183I	T	A	missense		Het	probably benign	0.024		phenotype	10/18/2018
72	537726		Ttyh1	1.000	R6823	G1	225.01	N		7	4122529	I60T	T	C	missense		Het	probably damaging	0.972		phenotype	10/18/2018
73	537772		Ubn1	0.614	R6823	G1	225.01	N		16	5064547	S48A	T	G	missense		Het	probably damaging	0.998		phenotype	10/18/2018
74	537768		Ubr5	1.000	R6823	G1	225.01	N		15	37989598	N2019S	T	C	missense		Het	probably benign	0.075		phenotype	10/18/2018
75	537759		Wbp2	0.417	R6823	G1	225.01	N		11	116086910	N6D	T	C	missense		Het	probably benign	0.408		phenotype	10/18/2018
76	537738		Wdr59	0.950	R6823	G1	225.01	N		8	111459040	E810V	T	A	missense		Het	possibly damaging	0.951			10/18/2018
77	537775		Wiz	1.000	R6823	G1	225.01	N		17	32360421	D220G	T	C	missense		Het	probably damaging	0.991		phenotype	10/18/2018
78	537719		Yipf7	0.055	R6823	G1	225.01	N		5	69517070	L244P	A	G	missense		Het	probably damaging	0.999			10/18/2018
79	537748		Zdhhc17	0.000	R6823	G1	225.01	N		10	110955111	T366A	T	C	missense		Het	possibly damaging	0.907		phenotype	10/18/2018
80	537761		Zfp169	0.115	R6823	G1	225.01	N		13	48490996		A	T	unclassified		Het	probably benign			phenotype	10/18/2018
81	537770		Zfp707	0.138	R6823	G1	225.01	N		15	75969723		C	T	unclassified		Het	probably benign				10/18/2018
82	537730		Zfp788	0.055	R6823	G1	225.01	N		7	41649560	H540R	A	G	missense		Het	probably damaging	0.998	0.502		10/18/2018
[records 1 to 82 of 82]