Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00479:Cd209g'

332188

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Cd209g

Ensembl Gene

ENSMUSG00000079168

Gene Name

CD209g antigen

Synonyms

2310066I10Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.049) question?

Stock #

IGL00479

Quality Score

Status

Chromosome

Chromosomal Location

4184246-4187707 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 4185622 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Serine at position 19 (T19S)

Ref Sequence

ENSEMBL: ENSMUSP00000116397 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000130372]

AlphaFold

D3Z5D4

Predicted Effect

probably benign
Transcript: ENSMUST00000130372
AA Change: T19S

PolyPhen 2 Score 0.216 (Sensitivity: 0.91; Specificity: 0.88)

SMART Domains

Protein: ENSMUSP00000116397
Gene: ENSMUSG00000079168
AA Change: T19S

Domain	Start	End	E-Value	Type
low complexity region	15	27	N/A	INTRINSIC
low complexity region	44	51	N/A	INTRINSIC
CLECT	66	185	2.43e-32	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000207281

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 27 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Agrn	A	C	4: 156,255,029 (GRCm39)		probably benign	Het
Antkmt	A	G	17: 26,010,418 (GRCm39)	Y104H	probably damaging	Het
Arid4a	A	G	12: 71,119,367 (GRCm39)	K651E	probably damaging	Het
Atpaf2	A	T	11: 60,300,410 (GRCm39)		probably null	Het
Cd177	G	T	7: 24,457,440 (GRCm39)	S200R	probably benign	Het
Cxcr4	A	G	1: 128,516,792 (GRCm39)	W290R	probably damaging	Het
D930020B18Rik	T	C	10: 121,521,489 (GRCm39)	L491P	probably damaging	Het
Dnah7a	T	C	1: 53,458,843 (GRCm39)	D3765G	probably damaging	Het
Dpy19l4	T	G	4: 11,290,411 (GRCm39)	M327L	probably benign	Het
Eya3	G	A	4: 132,431,709 (GRCm39)	G314D	probably damaging	Het
Fmo1	G	A	1: 162,657,632 (GRCm39)	T503I	probably benign	Het
Galnt3	A	G	2: 65,925,628 (GRCm39)	S370P	probably damaging	Het
Gm5431	A	T	11: 48,786,241 (GRCm39)	S45T	probably benign	Het
Gnai3	A	G	3: 108,023,073 (GRCm39)		probably benign	Het
Gpat2	A	G	2: 127,276,381 (GRCm39)	E637G	probably damaging	Het
Gpr84	T	C	15: 103,217,834 (GRCm39)	Y81C	probably damaging	Het
Hnmt	A	T	2: 23,893,896 (GRCm39)	Y199*	probably null	Het
Homer1	G	T	13: 93,483,156 (GRCm39)	R81L	probably damaging	Het
Hspa4	A	T	11: 53,171,544 (GRCm39)		probably null	Het
Marchf6	A	G	15: 31,475,909 (GRCm39)	I649T	probably benign	Het
Mcm8	A	G	2: 132,659,094 (GRCm39)	N26S	probably benign	Het
Mgat5	T	C	1: 127,315,204 (GRCm39)	L310P	probably damaging	Het
Pah	T	C	10: 87,414,755 (GRCm39)	L369P	probably benign	Het
Parp4	A	C	14: 56,853,917 (GRCm39)	K844N	possibly damaging	Het
Tlr5	A	G	1: 182,801,394 (GRCm39)	T233A	probably benign	Het
Tsnaxip1	A	G	8: 106,568,055 (GRCm39)	T274A	probably benign	Het
Wdr48	A	G	9: 119,734,456 (GRCm39)	Y125C	probably damaging	Het

Other mutations in Cd209g

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R0085:Cd209g	UTSW	8	4,184,785 (GRCm39)	splice site	probably benign
R0554:Cd209g	UTSW	8	4,184,995 (GRCm39)	start gained	probably benign
R4022:Cd209g	UTSW	8	4,185,955 (GRCm39)	missense	possibly damaging	0.72
R4981:Cd209g	UTSW	8	4,186,845 (GRCm39)	missense	probably damaging	1.00
R6305:Cd209g	UTSW	8	4,186,809 (GRCm39)	missense	probably benign	0.42
R7094:Cd209g	UTSW	8	4,186,790 (GRCm39)	missense	possibly damaging	0.50
R7144:Cd209g	UTSW	8	4,185,189 (GRCm39)	start gained	probably benign
R7606:Cd209g	UTSW	8	4,186,839 (GRCm39)	missense	probably damaging	1.00
R8076:Cd209g	UTSW	8	4,185,195 (GRCm39)	start codon destroyed	probably null	0.88
R9459:Cd209g	UTSW	8	4,185,610 (GRCm39)	missense	probably benign
RF018:Cd209g	UTSW	8	4,187,398 (GRCm39)	missense	probably benign	0.07

Posted On

2015-08-05