Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00509:Gm15217'

332529

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm15217

Ensembl Gene

ENSMUSG00000079261

Gene Name

predicted gene 15217

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.133) question?

Stock #

IGL00509

Quality Score

Status

Chromosome

Chromosomal Location

46616981-46621065 bp(+) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to C at 46620768 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000098242 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000074077] [ENSMUST00000100676] [ENSMUST00000111826] [ENSMUST00000141358]

AlphaFold

A2CG07

Predicted Effect

probably benign
Transcript: ENSMUST00000074077

SMART Domains

Protein: ENSMUSP00000073720
Gene: ENSMUSG00000021835

Domain	Start	End	E-Value	Type
Pfam:TGFb_propeptide	13	276	1.7e-77	PFAM
TGFB	308	408	4.53e-67	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000100676

SMART Domains

Protein: ENSMUSP00000098242
Gene: ENSMUSG00000021835

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
Pfam:TGFb_propeptide	39	276	3.7e-55	PFAM
TGFB	308	408	4.53e-67	SMART

Predicted Effect

unknown
Transcript: ENSMUST00000111826
AA Change: S146P

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000127359

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000135408

Predicted Effect

unknown
Transcript: ENSMUST00000141358
AA Change: S63P

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000147092

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000226759

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000228667

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 34 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A930011G23Rik	T	C	5: 99,391,102 (GRCm39)		probably null	Het
Abr	A	G	11: 76,313,915 (GRCm39)	L514P	probably damaging	Het
Ahnak	T	A	19: 8,987,315 (GRCm39)	D2866E	possibly damaging	Het
Bfsp1	T	A	2: 143,673,812 (GRCm39)	T293S	probably damaging	Het
Ccr1	C	T	9: 123,764,090 (GRCm39)	V147I	probably benign	Het
Cd84	T	C	1: 171,679,704 (GRCm39)		probably null	Het
Cep192	T	C	18: 67,991,939 (GRCm39)	V1939A	possibly damaging	Het
Chrnb4	A	T	9: 54,943,878 (GRCm39)	L80Q	probably damaging	Het
Ckmt2	A	T	13: 92,011,382 (GRCm39)	L76H	probably damaging	Het
Cntnap2	C	T	6: 45,992,197 (GRCm39)	P375S	possibly damaging	Het
Cped1	A	T	6: 22,215,522 (GRCm39)	L685F	probably damaging	Het
Dab2ip	T	C	2: 35,610,025 (GRCm39)	S682P	probably damaging	Het
Dclk1	A	T	3: 55,154,707 (GRCm39)	T46S	probably damaging	Het
Eif2d	T	A	1: 131,094,089 (GRCm39)	C427S	probably benign	Het
Fat4	T	A	3: 38,943,188 (GRCm39)	Y694N	probably damaging	Het
Gpr35	T	C	1: 92,910,594 (GRCm39)	I102T	probably damaging	Het
Grk4	T	A	5: 34,873,634 (GRCm39)	N233K	probably damaging	Het
Hdac3	T	C	18: 38,087,938 (GRCm39)	D10G	possibly damaging	Het
Hexb	G	A	13: 97,318,437 (GRCm39)	T308M	probably damaging	Het
Inpp5j	C	A	11: 3,451,595 (GRCm39)	D436Y	possibly damaging	Het
Kif18a	A	G	2: 109,148,333 (GRCm39)	E609G	possibly damaging	Het
Kif24	T	C	4: 41,413,826 (GRCm39)		probably null	Het
Lrp4	G	A	2: 91,316,519 (GRCm39)		probably benign	Het
Mat2b	T	C	11: 40,575,554 (GRCm39)	K161E	possibly damaging	Het
Nek2	T	G	1: 191,559,490 (GRCm39)		probably benign	Het
Numa1	A	G	7: 101,662,493 (GRCm39)	T1965A	possibly damaging	Het
Oca2	G	A	7: 55,930,594 (GRCm39)	G137D	probably damaging	Het
Pdcl2	T	A	5: 76,472,959 (GRCm39)	D3V	probably damaging	Het
Ranbp17	T	C	11: 33,443,402 (GRCm39)	N91S	probably benign	Het
Siglech	A	T	7: 55,418,635 (GRCm39)	D146V	possibly damaging	Het
Slc4a3	C	T	1: 75,531,727 (GRCm39)	T898M	probably damaging	Het
Sp3	A	G	2: 72,768,406 (GRCm39)		probably benign	Het
Tln1	C	T	4: 43,542,719 (GRCm39)	V1396I	probably benign	Het
Ugt2a3	T	A	5: 87,473,514 (GRCm39)	M468L	probably damaging	Het

Other mutations in Gm15217

Allele	Source	Chr	Coord	Type	Predicted Effect
R0149:Gm15217	UTSW	14	46,617,841 (GRCm39)	intron	probably benign
R0256:Gm15217	UTSW	14	46,617,853 (GRCm39)	intron	probably benign
R0361:Gm15217	UTSW	14	46,617,841 (GRCm39)	intron	probably benign
R0441:Gm15217	UTSW	14	46,620,676 (GRCm39)	critical splice donor site	probably null
R1736:Gm15217	UTSW	14	46,620,663 (GRCm39)	intron	probably benign
R8055:Gm15217	UTSW	14	46,616,911 (GRCm39)	start gained	probably benign

Posted On

2015-08-05