Incidental Mutation 'IGL03199:Vmn2r38'
| ID |
412916 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn2r38
|
| Ensembl Gene |
ENSMUSG00000095773 |
| Gene Name |
vomeronasal 2, receptor 38 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Not available
|
| Stock # |
IGL03199
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
9077795-9100764 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 9078375 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Aspartic acid
at position 669
(V669D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000104194
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000108554]
|
| AlphaFold |
G3UYA8 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000108554
AA Change: V669D
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000104194
Gene: ENSMUSG00000095773
AA Change: V669D
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
Pfam:ANF_receptor
|
73 |
469 |
3.5e-33 |
PFAM |
|
Pfam:NCD3G
|
512 |
565 |
1.4e-20 |
PFAM |
|
Pfam:7tm_3
|
598 |
833 |
6.4e-54 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 24 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930407I10Rik |
T |
C |
15: 81,946,556 (GRCm39) |
I151T |
possibly damaging |
Het |
| Alms1 |
T |
A |
6: 85,599,479 (GRCm39) |
M1904K |
possibly damaging |
Het |
| Chsy3 |
T |
A |
18: 59,309,473 (GRCm39) |
F242Y |
probably damaging |
Het |
| Cwf19l2 |
G |
A |
9: 3,477,830 (GRCm39) |
G845D |
probably damaging |
Het |
| Cyfip2 |
A |
G |
11: 46,167,670 (GRCm39) |
I244T |
probably benign |
Het |
| Dnah10 |
A |
T |
5: 124,894,761 (GRCm39) |
Q3499L |
probably benign |
Het |
| Fat3 |
A |
G |
9: 16,288,344 (GRCm39) |
V393A |
possibly damaging |
Het |
| Fcamr |
T |
A |
1: 130,740,655 (GRCm39) |
V358D |
probably damaging |
Het |
| Fndc3c1 |
T |
A |
X: 105,479,993 (GRCm39) |
K696N |
possibly damaging |
Het |
| Igkv2-112 |
G |
A |
6: 68,197,000 (GRCm39) |
M12I |
probably benign |
Het |
| Macc1 |
T |
C |
12: 119,410,156 (GRCm39) |
M308T |
probably benign |
Het |
| Map4k1 |
A |
G |
7: 28,682,842 (GRCm39) |
E16G |
probably damaging |
Het |
| Myl7 |
C |
T |
11: 5,848,205 (GRCm39) |
G50R |
probably damaging |
Het |
| Ncapg2 |
T |
A |
12: 116,382,856 (GRCm39) |
L229H |
probably damaging |
Het |
| Or10d4b |
A |
G |
9: 39,535,240 (GRCm39) |
I272V |
probably benign |
Het |
| Prkcz |
A |
G |
4: 155,357,441 (GRCm39) |
F157L |
possibly damaging |
Het |
| Sult2a1 |
C |
A |
7: 13,566,585 (GRCm39) |
G130V |
probably damaging |
Het |
| Trim27 |
G |
A |
13: 21,375,421 (GRCm39) |
|
probably null |
Het |
| Trim43b |
T |
G |
9: 88,971,481 (GRCm39) |
Q225P |
probably damaging |
Het |
| Ugt2b34 |
A |
G |
5: 87,054,739 (GRCm39) |
L14P |
unknown |
Het |
| Vmn1r209 |
A |
T |
13: 22,990,220 (GRCm39) |
S157T |
possibly damaging |
Het |
| Vps35l |
T |
C |
7: 118,365,611 (GRCm39) |
S15P |
probably benign |
Het |
| Zfp422 |
T |
C |
6: 116,603,912 (GRCm39) |
Q29R |
probably benign |
Het |
| Zfp623 |
C |
T |
15: 75,819,119 (GRCm39) |
A25V |
probably benign |
Het |
|
| Other mutations in Vmn2r38 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02805:Vmn2r38
|
APN |
7 |
9,078,546 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1619:Vmn2r38
|
UTSW |
7 |
9,078,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3154:Vmn2r38
|
UTSW |
7 |
9,097,689 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3909:Vmn2r38
|
UTSW |
7 |
9,078,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4302:Vmn2r38
|
UTSW |
7 |
9,100,562 (GRCm39) |
splice site |
probably null |
|
|
R5106:Vmn2r38
|
UTSW |
7 |
9,078,169 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5187:Vmn2r38
|
UTSW |
7 |
9,100,571 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5575:Vmn2r38
|
UTSW |
7 |
9,078,635 (GRCm39) |
nonsense |
probably null |
|
|
R5653:Vmn2r38
|
UTSW |
7 |
9,100,764 (GRCm39) |
start codon destroyed |
probably null |
1.00 |
|
R6156:Vmn2r38
|
UTSW |
7 |
9,097,611 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6970:Vmn2r38
|
UTSW |
7 |
9,078,340 (GRCm39) |
nonsense |
probably null |
|
|
R7107:Vmn2r38
|
UTSW |
7 |
9,093,728 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7231:Vmn2r38
|
UTSW |
7 |
9,100,637 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7419:Vmn2r38
|
UTSW |
7 |
9,078,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7963:Vmn2r38
|
UTSW |
7 |
9,095,854 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8788:Vmn2r38
|
UTSW |
7 |
9,078,482 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9639:Vmn2r38
|
UTSW |
7 |
9,078,063 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9773:Vmn2r38
|
UTSW |
7 |
9,097,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Posted On |
2016-08-02 |
Incidental Mutation