Incidental Mutation 'IGL01535:Vmn1r177'
| ID |
89925 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r177
|
| Ensembl Gene |
ENSMUSG00000057513 |
| Gene Name |
vomeronasal 1 receptor 177 |
| Synonyms |
V1rd12 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.075)
|
| Stock # |
IGL01535
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
23564945-23565874 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 23565765 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Leucine
at position 37
(H37L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000073621
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000073967]
|
| AlphaFold |
E9PXM3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000073967
AA Change: H37L
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000073621
Gene: ENSMUSG00000057513
AA Change: H37L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
8 |
299 |
4.1e-13 |
PFAM |
|
Pfam:V1R
|
41 |
297 |
5.3e-14 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000207027
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 27 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamts19 |
T |
A |
18: 59,101,891 (GRCm39) |
S654T |
probably benign |
Het |
| Brd10 |
T |
C |
19: 29,731,212 (GRCm39) |
H600R |
possibly damaging |
Het |
| Cacnb3 |
A |
T |
15: 98,537,469 (GRCm39) |
Q49L |
probably benign |
Het |
| Dapk1 |
A |
G |
13: 60,878,845 (GRCm39) |
|
probably benign |
Het |
| Dop1b |
T |
A |
16: 93,566,846 (GRCm39) |
L1091* |
probably null |
Het |
| Epb42 |
A |
G |
2: 120,858,169 (GRCm39) |
V263A |
probably damaging |
Het |
| Fig4 |
T |
G |
10: 41,132,490 (GRCm39) |
S439R |
probably benign |
Het |
| Gatc |
A |
T |
5: 115,479,048 (GRCm39) |
V54E |
possibly damaging |
Het |
| Hook2 |
T |
C |
8: 85,729,618 (GRCm39) |
L686P |
probably benign |
Het |
| Med12l |
A |
T |
3: 59,169,680 (GRCm39) |
T1615S |
probably damaging |
Het |
| Msr1 |
C |
T |
8: 40,064,714 (GRCm39) |
G320D |
probably benign |
Het |
| Nbeal1 |
T |
A |
1: 60,256,414 (GRCm39) |
F220I |
probably damaging |
Het |
| Or14j2 |
T |
A |
17: 37,885,679 (GRCm39) |
I212F |
possibly damaging |
Het |
| Or2l5 |
G |
A |
16: 19,334,228 (GRCm39) |
H53Y |
probably benign |
Het |
| Pcdh10 |
A |
T |
3: 45,334,078 (GRCm39) |
I131F |
probably damaging |
Het |
| Phlpp2 |
A |
G |
8: 110,660,697 (GRCm39) |
E784G |
possibly damaging |
Het |
| Prr36 |
A |
T |
8: 4,264,043 (GRCm39) |
|
probably benign |
Het |
| Ptprq |
G |
A |
10: 107,535,457 (GRCm39) |
S436L |
probably benign |
Het |
| Rock1 |
T |
A |
18: 10,132,119 (GRCm39) |
|
probably benign |
Het |
| Sash1 |
T |
G |
10: 8,617,341 (GRCm39) |
T522P |
probably damaging |
Het |
| Serpinb2 |
T |
C |
1: 107,447,503 (GRCm39) |
|
probably null |
Het |
| Supt16 |
T |
C |
14: 52,414,647 (GRCm39) |
K422E |
probably damaging |
Het |
| Syt14 |
T |
G |
1: 192,669,073 (GRCm39) |
D60A |
probably damaging |
Het |
| Tbc1d2b |
A |
C |
9: 90,097,526 (GRCm39) |
|
probably benign |
Het |
| Thsd7b |
T |
C |
1: 129,605,954 (GRCm39) |
I565T |
possibly damaging |
Het |
| Ttn |
A |
G |
2: 76,564,536 (GRCm39) |
Y28534H |
probably damaging |
Het |
| Vps13b |
A |
T |
15: 35,455,103 (GRCm39) |
N671Y |
possibly damaging |
Het |
|
| Other mutations in Vmn1r177 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01456:Vmn1r177
|
APN |
7 |
23,565,753 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
IGL01504:Vmn1r177
|
APN |
7 |
23,565,835 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01551:Vmn1r177
|
APN |
7 |
23,565,688 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01647:Vmn1r177
|
APN |
7 |
23,565,600 (GRCm39) |
missense |
probably damaging |
1.00 |
|
ANU74:Vmn1r177
|
UTSW |
7 |
23,565,645 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0396:Vmn1r177
|
UTSW |
7 |
23,565,022 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0894:Vmn1r177
|
UTSW |
7 |
23,565,475 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1446:Vmn1r177
|
UTSW |
7 |
23,565,765 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1835:Vmn1r177
|
UTSW |
7 |
23,565,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1893:Vmn1r177
|
UTSW |
7 |
23,565,573 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1995:Vmn1r177
|
UTSW |
7 |
23,565,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2206:Vmn1r177
|
UTSW |
7 |
23,565,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3889:Vmn1r177
|
UTSW |
7 |
23,565,289 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4458:Vmn1r177
|
UTSW |
7 |
23,565,645 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4579:Vmn1r177
|
UTSW |
7 |
23,565,772 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5290:Vmn1r177
|
UTSW |
7 |
23,565,498 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6128:Vmn1r177
|
UTSW |
7 |
23,565,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6128:Vmn1r177
|
UTSW |
7 |
23,565,267 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6730:Vmn1r177
|
UTSW |
7 |
23,565,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6785:Vmn1r177
|
UTSW |
7 |
23,565,562 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7100:Vmn1r177
|
UTSW |
7 |
23,565,535 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7738:Vmn1r177
|
UTSW |
7 |
23,565,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8191:Vmn1r177
|
UTSW |
7 |
23,565,736 (GRCm39) |
nonsense |
probably null |
|
|
R8980:Vmn1r177
|
UTSW |
7 |
23,565,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9723:Vmn1r177
|
UTSW |
7 |
23,565,774 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9771:Vmn1r177
|
UTSW |
7 |
23,565,657 (GRCm39) |
missense |
probably damaging |
0.98 |
|
X0020:Vmn1r177
|
UTSW |
7 |
23,565,718 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Vmn1r177
|
UTSW |
7 |
23,565,360 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Posted On |
2013-12-03 |
Incidental Mutation