Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01912:Ubxn2b'

179849

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ubxn2b

Ensembl Gene

ENSMUSG00000028243

Gene Name

UBX domain protein 2B

Synonyms

6430407D20Rik, 3110003A22Rik

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.281) question?

Stock #

IGL01912

Quality Score

Status

Chromosome

Chromosomal Location

6191105-6219788 bp(+) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

T to A at 6203767 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000029907 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000029907]

AlphaFold

Q0KL01

Predicted Effect

probably null
Transcript: ENSMUST00000029907

SMART Domains

Protein: ENSMUSP00000029907
Gene: ENSMUSG00000028243

Domain	Start	End	E-Value	Type
low complexity region	8	25	N/A	INTRINSIC
SEP	138	232	3.5e-39	SMART
UBX	251	330	1.05e-8	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 27 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc8	A	T	7: 45,769,934 (GRCm39)	D860E	probably damaging	Het
Actl11	C	A	9: 107,806,844 (GRCm39)	P389Q	probably damaging	Het
Bsg	G	T	10: 79,545,974 (GRCm39)	G103W	probably null	Het
Camk2d	T	A	3: 126,604,281 (GRCm39)		probably null	Het
Clcn7	T	C	17: 25,371,983 (GRCm39)		probably benign	Het
Dctd	C	T	8: 48,564,697 (GRCm39)		probably benign	Het
Dpy19l1	C	T	9: 24,396,365 (GRCm39)	R117Q	probably damaging	Het
Esyt2	T	C	12: 116,303,229 (GRCm39)	I289T	probably damaging	Het
Exoc6b	A	C	6: 84,602,156 (GRCm39)	C753G	probably damaging	Het
Gm10718	A	T	9: 3,025,118 (GRCm39)	Y194F	probably benign	Het
Gm21738	G	A	14: 19,416,979 (GRCm38)	S144L	probably benign	Het
Gm3633	T	C	14: 42,462,743 (GRCm39)		probably benign	Het
Hrh3	A	T	2: 179,743,169 (GRCm39)	V153D	probably damaging	Het
Krt77	T	A	15: 101,772,286 (GRCm39)		probably benign	Het
Nat3	T	A	8: 68,000,398 (GRCm39)	C92*	probably null	Het
Nckap1l	T	A	15: 103,382,573 (GRCm39)	L525M	probably benign	Het
Nrp2	T	A	1: 62,810,896 (GRCm39)	C646S	probably damaging	Het
Or10a3m	T	C	7: 108,313,465 (GRCm39)	Y290H	possibly damaging	Het
Or2ag16	T	A	7: 106,352,199 (GRCm39)	Y132F	probably damaging	Het
Or52n20	T	C	7: 104,320,440 (GRCm39)	I177T	possibly damaging	Het
Orc1	T	C	4: 108,447,941 (GRCm39)	Y63H	probably damaging	Het
Otud4	T	C	8: 80,400,466 (GRCm39)	V1059A	probably benign	Het
Ptprm	A	G	17: 67,353,113 (GRCm39)	V235A	probably benign	Het
Rab3ip	G	T	10: 116,742,997 (GRCm39)	Q443K	probably benign	Het
Tnc	C	A	4: 63,926,977 (GRCm39)	D850Y	probably damaging	Het
Vmn1r233	T	A	17: 21,214,467 (GRCm39)	Y161F	probably benign	Het
Vmn1r54	T	C	6: 90,246,442 (GRCm39)	S119P	probably damaging	Het

Other mutations in Ubxn2b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02096:Ubxn2b	APN	4	6,214,749 (GRCm39)	missense	probably damaging	1.00
IGL02272:Ubxn2b	APN	4	6,216,071 (GRCm39)	missense	probably damaging	1.00
R0081:Ubxn2b	UTSW	4	6,203,875 (GRCm39)	splice site	probably benign
R0482:Ubxn2b	UTSW	4	6,196,404 (GRCm39)	splice site	probably null
R1903:Ubxn2b	UTSW	4	6,208,889 (GRCm39)	missense	possibly damaging	0.82
R4206:Ubxn2b	UTSW	4	6,204,565 (GRCm39)	missense	probably damaging	0.99
R5071:Ubxn2b	UTSW	4	6,214,746 (GRCm39)	missense	probably damaging	1.00
R7622:Ubxn2b	UTSW	4	6,214,692 (GRCm39)	missense	probably damaging	0.98
R8034:Ubxn2b	UTSW	4	6,191,167 (GRCm39)	missense	probably benign	0.06
R8836:Ubxn2b	UTSW	4	6,216,061 (GRCm39)	missense	probably damaging	1.00
R9156:Ubxn2b	UTSW	4	6,214,646 (GRCm39)	missense	probably damaging	1.00
R9413:Ubxn2b	UTSW	4	6,204,607 (GRCm39)	missense	probably damaging	1.00

Posted On

2014-05-07