Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02017:Mxra7'

183807

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Mxra7

Ensembl Gene

ENSMUSG00000020814

Gene Name

matrix-remodelling associated 7

Synonyms

1810057P16Rik, E130302J09Rik

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02017

Quality Score

Status

Chromosome

Chromosomal Location

116694226-116718953 bp(-) (GRCm39)

Type of Mutation

critical splice donor site (2 bp from exon)

DNA Base Change (assembly)

A to G at 116702747 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000038213 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000021170] [ENSMUST00000021170] [ENSMUST00000047715] [ENSMUST00000150015]

AlphaFold

Q9CZH7

Predicted Effect

probably null
Transcript: ENSMUST00000021170

SMART Domains

Protein: ENSMUSP00000021170
Gene: ENSMUSG00000020814

Domain	Start	End	E-Value	Type
signal peptide	1	32	N/A	INTRINSIC
low complexity region	44	68	N/A	INTRINSIC
low complexity region	74	87	N/A	INTRINSIC
low complexity region	100	108	N/A	INTRINSIC
low complexity region	134	139	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000021170

SMART Domains

Protein: ENSMUSP00000021170
Gene: ENSMUSG00000020814

Domain	Start	End	E-Value	Type
signal peptide	1	32	N/A	INTRINSIC
low complexity region	44	68	N/A	INTRINSIC
low complexity region	74	87	N/A	INTRINSIC
low complexity region	100	108	N/A	INTRINSIC
low complexity region	134	139	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000047715

SMART Domains

Protein: ENSMUSP00000038213
Gene: ENSMUSG00000020814

Domain	Start	End	E-Value	Type
signal peptide	1	32	N/A	INTRINSIC
low complexity region	44	68	N/A	INTRINSIC
low complexity region	74	87	N/A	INTRINSIC
low complexity region	100	108	N/A	INTRINSIC
low complexity region	134	139	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000150015

SMART Domains

Protein: ENSMUSP00000134412
Gene: ENSMUSG00000020814

Domain	Start	End	E-Value	Type
signal peptide	1	32	N/A	INTRINSIC
low complexity region	44	68	N/A	INTRINSIC
low complexity region	74	87	N/A	INTRINSIC
low complexity region	100	108	N/A	INTRINSIC
low complexity region	134	139	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 31 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adam5	A	T	8: 25,271,775 (GRCm39)	I544N	probably benign	Het
Ago2	T	C	15: 72,998,366 (GRCm39)	T271A	probably benign	Het
Aox3	A	C	1: 58,160,151 (GRCm39)	K111N	probably damaging	Het
Arhgap39	G	A	15: 76,621,237 (GRCm39)	R455C	probably damaging	Het
Brcc3	A	G	X: 74,466,389 (GRCm39)	D67G	possibly damaging	Het
Crot	T	G	5: 9,020,046 (GRCm39)		probably benign	Het
Dipk1c	A	T	18: 84,754,950 (GRCm39)	D142V	probably damaging	Het
Dusp5	A	G	19: 53,525,937 (GRCm39)	H193R	probably damaging	Het
Ect2	G	A	3: 27,176,193 (GRCm39)	R644*	probably null	Het
Epn3	A	G	11: 94,385,852 (GRCm39)	S190P	probably benign	Het
Fam3c	A	G	6: 22,343,276 (GRCm39)	M1T	probably null	Het
Kif4	A	G	X: 99,681,960 (GRCm39)	N197S	probably benign	Het
Krt1c	T	C	15: 101,724,939 (GRCm39)	N224D	probably damaging	Het
Lama1	A	G	17: 68,071,720 (GRCm39)	H869R	probably benign	Het
Lrrc14	G	T	15: 76,597,942 (GRCm39)	R224L	probably damaging	Het
Macf1	T	C	4: 123,393,724 (GRCm39)	D864G	probably damaging	Het
Map3k11	C	T	19: 5,747,651 (GRCm39)	S603F	possibly damaging	Het
Myo5b	C	A	18: 74,850,070 (GRCm39)	D1139E	probably damaging	Het
Nek9	T	C	12: 85,376,697 (GRCm39)	Y228C	probably damaging	Het
Nxph1	T	C	6: 9,247,743 (GRCm39)	I238T	probably damaging	Het
Or2r11	T	C	6: 42,437,758 (GRCm39)	H65R	probably benign	Het
Or5ac17	A	G	16: 59,036,310 (GRCm39)	L222P	probably damaging	Het
Or9i1	T	A	19: 13,839,595 (GRCm39)	V146E	possibly damaging	Het
Pdpn	A	G	4: 142,997,140 (GRCm39)		probably benign	Het
Plbd2	T	C	5: 120,626,623 (GRCm39)	T329A	probably damaging	Het
Ptpn6	T	C	6: 124,709,449 (GRCm39)	D8G	probably damaging	Het
Rad54l2	T	C	9: 106,631,239 (GRCm39)	D16G	possibly damaging	Het
Slc43a3	A	G	2: 84,768,585 (GRCm39)	E68G	probably damaging	Het
Snph	G	A	2: 151,442,902 (GRCm39)	R16C	probably damaging	Het
Ttn	G	A	2: 76,555,560 (GRCm39)	R28736*	probably null	Het
Vmn1r18	G	A	6: 57,366,741 (GRCm39)	A271V	probably benign	Het

Other mutations in Mxra7

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL03299:Mxra7	APN	11	116,695,360 (GRCm39)	unclassified	probably benign
R0519:Mxra7	UTSW	11	116,701,612 (GRCm39)	critical splice donor site	probably null
R1115:Mxra7	UTSW	11	116,701,696 (GRCm39)	splice site	probably benign
R1741:Mxra7	UTSW	11	116,707,070 (GRCm39)	critical splice acceptor site	probably null
R4690:Mxra7	UTSW	11	116,707,078 (GRCm39)	splice site	probably null
R8313:Mxra7	UTSW	11	116,695,376 (GRCm39)	missense	probably damaging	1.00
Z1088:Mxra7	UTSW	11	116,695,432 (GRCm39)	missense	probably benign	0.29

Posted On

2014-05-07