Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00936:Taar7f'

28348

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Taar7f

Ensembl Gene

ENSMUSG00000100950

Gene Name

trace amine-associated receptor 7F

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.089) question?

Stock #

IGL00936

Quality Score

Status

Chromosome

Chromosomal Location

23925408-23926484 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 23926066 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 220 (V220A)

Ref Sequence

ENSEMBL: ENSMUSP00000071611 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000071691]

AlphaFold

Q5QD08

Predicted Effect

probably benign
Transcript: ENSMUST00000071691
AA Change: V220A

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000071611
Gene: ENSMUSG00000100950
AA Change: V220A

Domain	Start	End	E-Value	Type
Pfam:7TM_GPCR_Srx	56	261	1.6e-7	PFAM
Pfam:7TM_GPCR_Srsx	58	341	2e-10	PFAM
Pfam:7tm_1	64	326	6.6e-58	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000119318

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 8 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930562C15Rik	A	G	16: 4,682,510 (GRCm39)	T1053A	probably benign	Het
Col13a1	A	G	10: 61,712,069 (GRCm39)	M332T	probably damaging	Het
Cstdc1	A	C	2: 148,627,724 (GRCm39)	T124P	probably benign	Het
Cyth4	A	G	15: 78,504,113 (GRCm39)	E361G	probably benign	Het
Mrps22	T	C	9: 98,479,034 (GRCm39)	T114A	possibly damaging	Het
Nup155	T	C	15: 8,157,889 (GRCm39)		probably benign	Het
Or5b113	T	A	19: 13,341,988 (GRCm39)		probably benign	Het
Slc35g3	T	C	11: 69,651,317 (GRCm39)		probably null	Het

Other mutations in Taar7f

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01618:Taar7f	APN	10	23,926,239 (GRCm39)	missense	possibly damaging	0.56
IGL02567:Taar7f	APN	10	23,926,323 (GRCm39)	missense	probably damaging	0.97
R0096:Taar7f	UTSW	10	23,926,152 (GRCm39)	missense	probably benign	0.00
R0139:Taar7f	UTSW	10	23,926,312 (GRCm39)	missense	probably benign	0.04
R0363:Taar7f	UTSW	10	23,925,839 (GRCm39)	missense	probably damaging	1.00
R1776:Taar7f	UTSW	10	23,925,546 (GRCm39)	missense	probably benign	0.14
R1952:Taar7f	UTSW	10	23,925,747 (GRCm39)	missense	probably damaging	1.00
R2049:Taar7f	UTSW	10	23,926,323 (GRCm39)	missense	possibly damaging	0.65
R2280:Taar7f	UTSW	10	23,925,417 (GRCm39)	missense	probably benign
R3120:Taar7f	UTSW	10	23,925,478 (GRCm39)	missense	probably benign
R4210:Taar7f	UTSW	10	23,925,921 (GRCm39)	missense	probably damaging	1.00
R4211:Taar7f	UTSW	10	23,925,921 (GRCm39)	missense	probably damaging	1.00
R4587:Taar7f	UTSW	10	23,926,473 (GRCm39)	missense	probably damaging	0.97
R5092:Taar7f	UTSW	10	23,925,451 (GRCm39)	missense	probably benign
R5512:Taar7f	UTSW	10	23,926,321 (GRCm39)	missense	possibly damaging	0.89
R7439:Taar7f	UTSW	10	23,925,885 (GRCm39)	missense	possibly damaging	0.88
R7441:Taar7f	UTSW	10	23,925,885 (GRCm39)	missense	possibly damaging	0.88
R7839:Taar7f	UTSW	10	23,925,967 (GRCm39)	missense	possibly damaging	0.90
R8326:Taar7f	UTSW	10	23,925,811 (GRCm39)	missense	possibly damaging	0.81
R9443:Taar7f	UTSW	10	23,926,311 (GRCm39)	missense	probably benign	0.00
R9687:Taar7f	UTSW	10	23,925,727 (GRCm39)	missense	probably benign	0.19
RF021:Taar7f	UTSW	10	23,926,321 (GRCm39)	missense	possibly damaging	0.89

Posted On

2013-04-17