Mutagenetix > Incidental Mutation

Incidental Mutation 'R4288:Vmn1r227'

322112

Institutional Source

Beutler Lab

Gene Symbol

Vmn1r227

Ensembl Gene

ENSMUSG00000067951

Gene Name

vomeronasal 1 receptor 227

Synonyms

V1re6

MMRRC Submission

041653-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.183) question?

Stock #

R4288 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

20955468-20956388 bp(+) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

G to T at 20956092 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

A0A3B2W3R4

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000088829

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000179914

Meta Mutation Damage Score

0.0869

Coding Region Coverage

1x: 99.3%
3x: 98.7%
10x: 97.5%
20x: 95.8%

Validation Efficiency

97% (34/35)

Allele List at MGI

Other mutations in this stock

Total: 32 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acmsd	G	A	1: 127,666,309 (GRCm39)	V27M	probably damaging	Het
Acsl6	A	G	11: 54,227,912 (GRCm39)	T311A	probably benign	Het
Adss2	G	A	1: 177,604,078 (GRCm39)	R176W	probably damaging	Het
Akr7a5	T	C	4: 139,041,415 (GRCm39)	V108A	probably benign	Het
Atp13a1	A	G	8: 70,246,728 (GRCm39)	D209G	possibly damaging	Het
Bpnt2	A	C	4: 4,778,231 (GRCm39)	V169G	probably damaging	Het
Cdcp1	T	A	9: 123,012,693 (GRCm39)	I285F	probably damaging	Het
Ctnna2	C	T	6: 77,582,204 (GRCm39)	R339Q	probably damaging	Het
E130308A19Rik	G	A	4: 59,690,308 (GRCm39)	M47I	probably benign	Het
Exosc9	C	T	3: 36,617,365 (GRCm39)	T373I	probably benign	Het
Fat4	T	A	3: 38,945,912 (GRCm39)	S1602T	probably damaging	Het
Fbn2	T	C	18: 58,168,411 (GRCm39)	I2309V	probably damaging	Het
Fbxo42	T	C	4: 140,895,207 (GRCm39)	Y57H	probably damaging	Het
Fcrl5	A	G	3: 87,349,531 (GRCm39)	D102G	probably benign	Het
Garin5b	T	A	7: 4,773,722 (GRCm39)	N58Y	possibly damaging	Het
Gpr37l1	A	G	1: 135,088,922 (GRCm39)	V381A	probably damaging	Het
Hc	G	T	2: 34,920,414 (GRCm39)	A644E	probably damaging	Het
Hspg2	C	T	4: 137,246,251 (GRCm39)	R1010C	probably damaging	Het
Lpar5	T	C	6: 125,058,827 (GRCm39)	Y183H	probably benign	Het
Ltn1	T	A	16: 87,194,876 (GRCm39)	N1341I	possibly damaging	Het
Mms19	A	G	19: 41,933,992 (GRCm39)	L938P	probably damaging	Het
Neb	T	G	2: 52,149,312 (GRCm39)	E2516D	probably damaging	Het
Parp4	T	C	14: 56,844,951 (GRCm39)	V614A	probably damaging	Het
Pogk	A	G	1: 166,231,075 (GRCm39)	L84P	probably damaging	Het
Stard13	G	A	5: 150,968,642 (GRCm39)	T994M	probably damaging	Het
Stk4	A	G	2: 163,941,632 (GRCm39)	S283G	probably benign	Het
Ttn	T	C	2: 76,640,742 (GRCm39)	T13669A	probably benign	Het
Vil1	A	G	1: 74,457,684 (GRCm39)	T106A	probably benign	Het
Vmn1r18	A	G	6: 57,367,392 (GRCm39)	L54P	probably damaging	Het
Zfp267	A	G	3: 36,213,747 (GRCm39)	N27S	possibly damaging	Het
Zfp748	T	A	13: 67,689,202 (GRCm39)	H686L	probably damaging	Het
Zyg11a	C	T	4: 108,041,666 (GRCm39)	S658N	probably damaging	Het

Other mutations in Vmn1r227

Allele	Source	Chr	Coord	Type	Predicted Effect
R4091:Vmn1r227	UTSW	17	20,955,778 (GRCm39)	exon	noncoding transcript
R4289:Vmn1r227	UTSW	17	20,956,092 (GRCm39)	exon	noncoding transcript
R4783:Vmn1r227	UTSW	17	20,955,396 (GRCm39)	exon	noncoding transcript
R4829:Vmn1r227	UTSW	17	20,955,927 (GRCm39)	exon	noncoding transcript
R4877:Vmn1r227	UTSW	17	20,955,407 (GRCm39)	exon	noncoding transcript
R4943:Vmn1r227	UTSW	17	20,955,623 (GRCm39)	exon	noncoding transcript
R5017:Vmn1r227	UTSW	17	20,956,340 (GRCm39)	exon	noncoding transcript
R5225:Vmn1r227	UTSW	17	20,955,499 (GRCm39)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- GGATCCTGTTGATGCTAGTAAATATGC -3'
(R):5'- TTCATCAACCACCGACTGGG -3'

Sequencing Primer
(F):5'- GATGCTAGTAAATATGCTTTTCCCTG -3'
(R):5'- CCACCGACTGGGATTATCTAAAAGAG -3'

Posted On

2015-06-20