Incidental Mutation 'IGL00557:Iglv2'
ID 332605
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Iglv2
Ensembl Gene ENSMUSG00000076940
Gene Name immunoglobulin lambda variable 2
Synonyms
Accession Numbers
Essential gene? Not available question?
Stock # IGL00557
Quality Score
Status
Chromosome 16
Chromosomal Location 19079153-19079594 bp(-) (GRCm39)
Type of Mutation critical splice donor site
DNA Base Change (assembly) A to G at 19079547 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000142646 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000103752] [ENSMUST00000197518]
AlphaFold no structure available at present
Predicted Effect probably benign
Transcript: ENSMUST00000103752
SMART Domains Protein: ENSMUSP00000100466
Gene: ENSMUSG00000076940

DomainStartEndE-ValueType
low complexity region 5 18 N/A INTRINSIC
IGv 35 110 9.84e-12 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000197518
SMART Domains Protein: ENSMUSP00000142646
Gene: ENSMUSG00000076940

DomainStartEndE-ValueType
signal peptide 1 19 N/A INTRINSIC
IGv 36 111 9.84e-12 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 25 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Agpat3 A T 10: 78,109,516 (GRCm39) probably benign Het
Arhgap35 T C 7: 16,298,340 (GRCm39) T242A probably benign Het
Asb15 C A 6: 24,558,649 (GRCm39) R55S probably benign Het
Brca2 C T 5: 150,484,003 (GRCm39) R2941W probably benign Het
Chrng T C 1: 87,134,469 (GRCm39) V135A probably damaging Het
Corin G T 5: 72,462,231 (GRCm39) H859Q probably damaging Het
Cul7 A G 17: 46,963,434 (GRCm39) E208G probably damaging Het
Dnah6 T C 6: 73,172,603 (GRCm39) N285S possibly damaging Het
Ell2 T A 13: 75,904,409 (GRCm39) I166N probably damaging Het
Fsip2 A G 2: 82,821,657 (GRCm39) R5797G possibly damaging Het
Galntl6 T C 8: 59,364,451 (GRCm39) I20V possibly damaging Het
Glra2 A G X: 164,072,633 (GRCm39) F78L possibly damaging Het
Gm12258 A G 11: 58,746,896 (GRCm39) D51G probably benign Het
Gsta2 T A 9: 78,238,525 (GRCm39) K185* probably null Het
Hmgcr C T 13: 96,795,786 (GRCm39) D294N probably benign Het
Myo10 T A 15: 25,776,466 (GRCm39) L63H probably damaging Het
P2ry10b T C X: 106,215,243 (GRCm39) V201A probably benign Het
Psmb2 A G 4: 126,571,642 (GRCm39) probably null Het
Samd4 T A 14: 47,290,355 (GRCm39) L154H probably damaging Het
Sult2a4 A T 7: 13,718,870 (GRCm39) D124E probably damaging Het
Trav9-1 A T 14: 53,725,815 (GRCm39) Y43F probably damaging Het
Trpv2 A G 11: 62,483,681 (GRCm39) N506S probably damaging Het
Ube3c T C 5: 29,824,227 (GRCm39) S474P probably damaging Het
Wdr87-ps A G 7: 29,235,227 (GRCm39) noncoding transcript Het
Zfp942 A T 17: 22,148,042 (GRCm39) C196S probably benign Het
Other mutations in Iglv2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01376:Iglv2 APN 16 19,079,315 (GRCm39) missense possibly damaging 0.61
R3831:Iglv2 UTSW 16 19,079,593 (GRCm39) start codon destroyed probably null 0.53
R3832:Iglv2 UTSW 16 19,079,593 (GRCm39) start codon destroyed probably null 0.53
R3833:Iglv2 UTSW 16 19,079,593 (GRCm39) start codon destroyed probably null 0.53
R7195:Iglv2 UTSW 16 19,079,260 (GRCm39) missense not run
R9149:Iglv2 UTSW 16 19,079,434 (GRCm39) missense probably damaging 1.00
R9762:Iglv2 UTSW 16 19,079,548 (GRCm39) critical splice donor site probably benign
Posted On 2015-08-05