Incidental Mutation 'IGL02821:1700025F22Rik'
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ID360994
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol 1700025F22Rik
Ensembl Gene ENSMUSG00000024728
Gene NameRIKEN cDNA 1700025F22 gene
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.039) question?
Stock #IGL02821
Quality Score
Status
Chromosome19
Chromosomal Location11139664-11165320 bp(-) (GRCm38)
Type of Mutationmakesense
DNA Base Change (assembly) A to G at 11141533 bp
ZygosityHeterozygous
Amino Acid Change Stop codon to Glutamine at position 71 (*71Q)
Ref Sequence ENSEMBL: ENSMUSP00000137806 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000078770] [ENSMUST00000180678] [ENSMUST00000181284] [ENSMUST00000181567]
Predicted Effect probably null
Transcript: ENSMUST00000078770
AA Change: *112Q
SMART Domains Protein: ENSMUSP00000077828
Gene: ENSMUSG00000024728
AA Change: *112Q

DomainStartEndE-ValueType
Pfam:CD20 17 101 1.2e-8 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000180678
AA Change: *71Q
SMART Domains Protein: ENSMUSP00000137968
Gene: ENSMUSG00000024728
AA Change: *71Q

DomainStartEndE-ValueType
transmembrane domain 5 25 N/A INTRINSIC
transmembrane domain 40 62 N/A INTRINSIC
Predicted Effect probably null
Transcript: ENSMUST00000181284
AA Change: *71Q
SMART Domains Protein: ENSMUSP00000137829
Gene: ENSMUSG00000024728
AA Change: *71Q

DomainStartEndE-ValueType
transmembrane domain 5 25 N/A INTRINSIC
transmembrane domain 40 62 N/A INTRINSIC
Predicted Effect probably null
Transcript: ENSMUST00000181567
AA Change: *71Q
SMART Domains Protein: ENSMUSP00000137806
Gene: ENSMUSG00000024728
AA Change: *71Q

DomainStartEndE-ValueType
transmembrane domain 5 25 N/A INTRINSIC
transmembrane domain 40 62 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 45 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700015F17Rik G A 5: 5,452,039 Q138* probably null Het
4930474N05Rik T C 14: 36,096,516 L157S probably benign Het
Adam15 A G 3: 89,345,356 S309P probably damaging Het
Agtpbp1 A T 13: 59,482,601 M772K possibly damaging Het
Ankfn1 T C 11: 89,391,616 M402V probably benign Het
Anln G A 9: 22,358,122 T822I possibly damaging Het
Atp13a4 A G 16: 29,441,307 V589A probably benign Het
Ccm2l C T 2: 153,067,859 L44F probably damaging Het
Cd177 A T 7: 24,744,393 L760Q probably damaging Het
Cd177 G T 7: 24,744,394 L760M probably damaging Het
Cfap69 T C 5: 5,664,017 E5G probably benign Het
Col4a1 G A 8: 11,221,375 T753I probably benign Het
Col6a3 T A 1: 90,803,878 D1551V probably damaging Het
Ddx20 A G 3: 105,679,277 V584A probably benign Het
Dopey1 C A 9: 86,520,156 H1136Q probably benign Het
Egf T C 3: 129,702,479 E329G probably damaging Het
Eif3c A G 7: 126,558,659 V337A probably benign Het
Eif3f G T 7: 108,934,674 probably benign Het
Eif3f C T 7: 108,934,675 probably benign Het
Evc T A 5: 37,326,396 I187F probably benign Het
Fam117a T G 11: 95,363,989 Het
H2-M10.4 A T 17: 36,460,431 V285E probably damaging Het
Hps4 G T 5: 112,375,441 M608I probably benign Het
Idh3b T A 2: 130,284,401 N6I probably benign Het
Itgam A T 7: 128,076,109 M169L probably damaging Het
Kcnn3 G A 3: 89,662,722 G614D possibly damaging Het
Kcnn3 A G 3: 89,520,974 N169S possibly damaging Het
Mn1 A T 5: 111,421,851 K1229M probably damaging Het
Nckap5 A G 1: 126,027,816 M401T probably damaging Het
Olfr366 T C 2: 37,220,100 S204P probably damaging Het
Olfr891 T C 9: 38,180,668 N52D possibly damaging Het
Olfr985 T G 9: 40,127,265 E232A probably benign Het
Sim2 G A 16: 94,097,188 V94M probably damaging Het
Slc46a3 G A 5: 147,886,012 T340M probably benign Het
Ssc4d A G 5: 135,966,069 Het
Tcrg-V4 T A 13: 19,185,252 D55E possibly damaging Het
Trav12-1 A G 14: 53,538,459 D22G probably damaging Het
Trps1 G A 15: 50,660,877 T969M probably damaging Het
Ttn T A 2: 76,889,550 probably benign Het
Ubqln4 A G 3: 88,563,151 N310S probably benign Het
Vapa T C 17: 65,582,761 probably benign Het
Vmn1r65 T C 7: 6,008,894 T114A possibly damaging Het
Vps13d T C 4: 145,148,762 E1725G probably damaging Het
Vps53 A G 11: 76,136,317 probably benign Het
Xkr9 T C 1: 13,672,575 L28P probably damaging Het
Other mutations in 1700025F22Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0963:1700025F22Rik UTSW 19 11141557 missense possibly damaging 0.94
R1490:1700025F22Rik UTSW 19 11141538 missense probably benign
R5528:1700025F22Rik UTSW 19 11141635 missense possibly damaging 0.90
R6324:1700025F22Rik UTSW 19 11163447 missense probably benign 0.01
R6351:1700025F22Rik UTSW 19 11142401 missense probably damaging 1.00
Posted On2015-12-18