Incidental Mutation 'IGL02980:Armt1'
| ID |
406523 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Armt1
|
| Ensembl Gene |
ENSMUSG00000061759 |
| Gene Name |
acidic residue methyltransferase 1 |
| Synonyms |
1700052N19Rik |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.148)
|
| Stock # |
IGL02980 (G1)
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
10 |
| Chromosomal Location |
4382572-4405140 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
A to G
at 4400643 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000115624
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000095893]
[ENSMUST00000118544]
[ENSMUST00000152294]
|
| AlphaFold |
A6H630 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000095893
|
| SMART Domains |
Protein: ENSMUSP00000093581
Gene: ENSMUSG00000061759
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF89
|
20 |
417 |
1.3e-125 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000118544
|
| SMART Domains |
Protein: ENSMUSP00000114073
Gene: ENSMUSG00000061759
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF89
|
20 |
187 |
1.2e-33 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000143037
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152294
|
| Coding Region Coverage |
- 1x: 0.0%
- 3x: 0.0%
- 10x: 0.0%
- 20x: 0.0%
|
| Validation Efficiency |
97% (35/36) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 36 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acvr1b |
A |
G |
15: 101,100,959 (GRCm39) |
R374G |
probably damaging |
Het |
| Adam28 |
A |
T |
14: 68,857,255 (GRCm39) |
S584T |
probably benign |
Het |
| Akap1 |
A |
T |
11: 88,735,990 (GRCm39) |
I224N |
probably benign |
Het |
| Ankdd1b |
C |
T |
13: 96,572,448 (GRCm39) |
R214Q |
probably benign |
Het |
| C1rl |
T |
C |
6: 124,485,487 (GRCm39) |
I286T |
probably benign |
Het |
| Cdh23 |
T |
C |
10: 60,150,399 (GRCm39) |
T2528A |
probably damaging |
Het |
| Col4a4 |
A |
G |
1: 82,447,198 (GRCm39) |
|
probably null |
Het |
| Dag1 |
A |
G |
9: 108,095,237 (GRCm39) |
I85T |
probably benign |
Het |
| Elf2 |
A |
G |
3: 51,172,379 (GRCm39) |
V86A |
possibly damaging |
Het |
| Emsy |
T |
C |
7: 98,268,587 (GRCm39) |
T485A |
probably damaging |
Het |
| Fam169a |
T |
C |
13: 97,250,188 (GRCm39) |
|
probably null |
Het |
| Hsd17b4 |
A |
G |
18: 50,279,585 (GRCm39) |
H188R |
probably benign |
Het |
| Ighv9-2 |
C |
T |
12: 114,072,839 (GRCm39) |
V45M |
probably damaging |
Het |
| Kifbp |
A |
C |
10: 62,394,947 (GRCm39) |
L565W |
probably damaging |
Het |
| Lama3 |
C |
T |
18: 12,686,288 (GRCm39) |
L2784F |
probably benign |
Het |
| Ms4a4c |
G |
T |
19: 11,393,747 (GRCm39) |
A64S |
probably benign |
Het |
| Nudt22 |
A |
G |
19: 6,970,500 (GRCm39) |
L280P |
probably damaging |
Het |
| Oscar |
T |
C |
7: 3,614,062 (GRCm39) |
|
probably benign |
Het |
| Paics |
A |
G |
5: 77,114,102 (GRCm39) |
I321V |
probably benign |
Het |
| Pappa |
A |
T |
4: 65,226,011 (GRCm39) |
H1288L |
probably benign |
Het |
| Pla2r1 |
T |
C |
2: 60,345,390 (GRCm39) |
E322G |
possibly damaging |
Het |
| Poldip2 |
T |
A |
11: 78,412,054 (GRCm39) |
M330K |
probably damaging |
Het |
| Potefam1 |
G |
A |
2: 110,994,818 (GRCm39) |
H232Y |
unknown |
Het |
| Recql5 |
T |
C |
11: 115,784,770 (GRCm39) |
|
probably null |
Het |
| Rnf145 |
A |
G |
11: 44,452,484 (GRCm39) |
M488V |
probably benign |
Het |
| Rrp1b |
T |
A |
17: 32,269,013 (GRCm39) |
D170E |
possibly damaging |
Het |
| Slamf7 |
T |
C |
1: 171,468,566 (GRCm39) |
S109G |
possibly damaging |
Het |
| Slf1 |
A |
G |
13: 77,192,123 (GRCm39) |
S904P |
possibly damaging |
Het |
| St7 |
C |
A |
6: 17,749,545 (GRCm39) |
|
probably benign |
Het |
| Stk25 |
A |
G |
1: 93,555,390 (GRCm39) |
S102P |
probably damaging |
Het |
| Supt6 |
C |
T |
11: 78,116,548 (GRCm39) |
A659T |
probably damaging |
Het |
| Tdrp |
A |
C |
8: 14,003,918 (GRCm39) |
S140A |
probably damaging |
Het |
| Thbs3 |
A |
G |
3: 89,130,451 (GRCm39) |
N527D |
probably benign |
Het |
| Tsnaxip1 |
G |
T |
8: 106,568,842 (GRCm39) |
V444L |
probably damaging |
Het |
| U2af2 |
A |
G |
7: 5,071,042 (GRCm39) |
I116V |
probably benign |
Het |
| Zfp931 |
C |
A |
2: 177,711,409 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Armt1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00907:Armt1
|
APN |
10 |
4,454,051 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
IGL01018:Armt1
|
APN |
10 |
4,404,237 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01018:Armt1
|
APN |
10 |
4,400,732 (GRCm39) |
missense |
probably benign |
|
|
IGL02198:Armt1
|
APN |
10 |
4,404,064 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03104:Armt1
|
APN |
10 |
4,389,615 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0620:Armt1
|
UTSW |
10 |
4,382,689 (GRCm39) |
missense |
probably benign |
0.38 |
|
R4248:Armt1
|
UTSW |
10 |
4,389,687 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5709:Armt1
|
UTSW |
10 |
4,384,903 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6058:Armt1
|
UTSW |
10 |
4,403,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6318:Armt1
|
UTSW |
10 |
4,400,859 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6410:Armt1
|
UTSW |
10 |
4,403,826 (GRCm39) |
missense |
probably benign |
|
|
R6998:Armt1
|
UTSW |
10 |
4,403,937 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7242:Armt1
|
UTSW |
10 |
4,403,475 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7268:Armt1
|
UTSW |
10 |
4,400,855 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R7432:Armt1
|
UTSW |
10 |
4,382,706 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7640:Armt1
|
UTSW |
10 |
4,403,572 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7715:Armt1
|
UTSW |
10 |
4,400,751 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8877:Armt1
|
UTSW |
10 |
4,400,864 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R8968:Armt1
|
UTSW |
10 |
4,404,150 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8973:Armt1
|
UTSW |
10 |
4,389,550 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9096:Armt1
|
UTSW |
10 |
4,384,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9404:Armt1
|
UTSW |
10 |
4,400,848 (GRCm39) |
frame shift |
probably null |
|
|
R9405:Armt1
|
UTSW |
10 |
4,400,848 (GRCm39) |
frame shift |
probably null |
|
|
R9408:Armt1
|
UTSW |
10 |
4,400,848 (GRCm39) |
frame shift |
probably null |
|
|
R9563:Armt1
|
UTSW |
10 |
4,400,848 (GRCm39) |
frame shift |
probably null |
|
|
R9785:Armt1
|
UTSW |
10 |
4,389,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Posted On |
2016-08-02 |
Incidental Mutation