Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01060:Gm12887'

50822

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm12887

Ensembl Gene

ENSMUSG00000078575

Gene Name

predicted gene 12887

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.070) question?

Stock #

IGL01060

Quality Score

Status

Chromosome

Chromosomal Location

121471468-121479300 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

C to T at 121473610 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000101872 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000106265]

AlphaFold

B1AVM1

Predicted Effect

probably benign
Transcript: ENSMUST00000106265

SMART Domains

Protein: ENSMUSP00000101872
Gene: ENSMUSG00000078575

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
Pfam:Palm_thioest	37	119	2.4e-10	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 29 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110038F14Rik	G	A	15: 76,834,475 (GRCm39)	V124I	probably damaging	Het
Anks4b	A	G	7: 119,773,148 (GRCm39)	T3A	possibly damaging	Het
Arhgef26	T	A	3: 62,247,542 (GRCm39)	S209T	probably benign	Het
Ccdc78	A	G	17: 26,007,806 (GRCm39)	D281G	probably damaging	Het
Ccnb3	A	T	X: 6,846,513 (GRCm39)	N1362K	probably benign	Het
Dnah2	T	C	11: 69,368,918 (GRCm39)	N1662S	possibly damaging	Het
Elp1	C	T	4: 56,784,537 (GRCm39)		probably null	Het
Ern2	T	A	7: 121,769,315 (GRCm39)	R904W	probably damaging	Het
Fam120c	C	T	X: 150,252,583 (GRCm39)	P1045S	probably benign	Het
Gpld1	G	A	13: 25,166,549 (GRCm39)	G627S	probably damaging	Het
Krt77	T	A	15: 101,769,315 (GRCm39)		probably benign	Het
Ltf	A	T	9: 110,851,950 (GRCm39)		probably null	Het
Map3k6	G	T	4: 132,974,613 (GRCm39)		probably null	Het
Nsd1	G	A	13: 55,411,242 (GRCm39)	G1431D	probably damaging	Het
Plekhm2	C	T	4: 141,369,956 (GRCm39)		probably null	Het
Popdc2	T	A	16: 38,194,327 (GRCm39)	N249K	probably damaging	Het
Ppm1h	A	G	10: 122,743,476 (GRCm39)	D400G	possibly damaging	Het
Rps6ka1	A	T	4: 133,588,181 (GRCm39)	S320T	probably damaging	Het
Rsph6a	C	T	7: 18,788,793 (GRCm39)	R42*	probably null	Het
Sap130	T	C	18: 31,848,496 (GRCm39)	L967P	probably damaging	Het
Smyd2	T	C	1: 189,629,667 (GRCm39)	E121G	possibly damaging	Het
Sspo	G	A	6: 48,426,413 (GRCm39)	W144*	probably null	Het
Taar6	A	G	10: 23,860,970 (GRCm39)	V192A	probably benign	Het
Tbc1d24	A	T	17: 24,404,802 (GRCm39)	V114E	probably damaging	Het
Trim16	T	C	11: 62,711,530 (GRCm39)	I67T	probably benign	Het
Ttll7	A	G	3: 146,615,337 (GRCm39)	D267G	possibly damaging	Het
Ttn	T	C	2: 76,720,073 (GRCm39)		probably benign	Het
Vmn2r56	T	A	7: 12,447,016 (GRCm39)	I379F	probably damaging	Het
Zfp14	T	C	7: 29,737,510 (GRCm39)	T492A	probably damaging	Het

Other mutations in Gm12887

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02113:Gm12887	APN	4	121,473,692 (GRCm39)	missense	probably benign	0.32
R0055:Gm12887	UTSW	4	121,473,666 (GRCm39)	missense	probably damaging	0.98
R0055:Gm12887	UTSW	4	121,473,666 (GRCm39)	missense	probably damaging	0.98
R1673:Gm12887	UTSW	4	121,473,655 (GRCm39)	missense	probably damaging	0.98
R1784:Gm12887	UTSW	4	121,473,715 (GRCm39)	missense	probably benign	0.44
R1843:Gm12887	UTSW	4	121,479,227 (GRCm39)	missense	probably damaging	0.98
R4231:Gm12887	UTSW	4	121,479,299 (GRCm39)	start codon destroyed	probably null	0.53
R5258:Gm12887	UTSW	4	121,472,897 (GRCm39)	missense	probably benign
R6528:Gm12887	UTSW	4	121,472,834 (GRCm39)	missense	probably damaging	1.00
R8037:Gm12887	UTSW	4	121,472,887 (GRCm39)	missense	probably damaging	1.00
R9038:Gm12887	UTSW	4	121,473,616 (GRCm39)	critical splice donor site	probably null
R9073:Gm12887	UTSW	4	121,479,238 (GRCm39)	splice site	probably null
R9157:Gm12887	UTSW	4	121,473,701 (GRCm39)	missense	probably benign	0.06
R9313:Gm12887	UTSW	4	121,473,701 (GRCm39)	missense	probably benign	0.06

Posted On

2013-06-21