Incidental Mutation 'R6841:Repin1'
| ID |
538026 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Repin1
|
| Ensembl Gene |
ENSMUSG00000052751 |
| Gene Name |
replication initiator 1 |
| Synonyms |
Zfp464, AP4, E430037F08Rik |
| MMRRC Submission |
044947-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6841 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
48570817-48576016 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 48574859 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Leucine
at position 593
(Q593L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000113548
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000009420]
[ENSMUST00000118229]
[ENSMUST00000135151]
[ENSMUST00000154010]
[ENSMUST00000163452]
[ENSMUST00000204095]
[ENSMUST00000204121]
[ENSMUST00000204521]
|
| AlphaFold |
Q5U4E2 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000009420
AA Change: Q540L
PolyPhen 2
Score 0.761 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000009420
Gene: ENSMUSG00000052751
AA Change: Q540L
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
52 |
72 |
3.47e1 |
SMART |
|
ZnF_C2H2
|
80 |
102 |
5.81e-2 |
SMART |
|
ZnF_C2H2
|
111 |
133 |
5.5e-3 |
SMART |
|
ZnF_C2H2
|
140 |
160 |
1.16e1 |
SMART |
|
ZnF_C2H2
|
172 |
194 |
3.89e-3 |
SMART |
|
low complexity region
|
196 |
224 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
229 |
251 |
1.67e-2 |
SMART |
|
ZnF_C2H2
|
257 |
279 |
4.94e-5 |
SMART |
|
ZnF_C2H2
|
285 |
307 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
353 |
375 |
4.72e-2 |
SMART |
|
ZnF_C2H2
|
381 |
403 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
409 |
431 |
1.79e-2 |
SMART |
|
ZnF_C2H2
|
437 |
459 |
4.24e-4 |
SMART |
|
ZnF_C2H2
|
465 |
487 |
6.52e-5 |
SMART |
|
ZnF_C2H2
|
493 |
515 |
2.61e-4 |
SMART |
|
ZnF_C2H2
|
521 |
543 |
1.45e-2 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000118229
AA Change: Q593L
PolyPhen 2
Score 0.949 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000113548
Gene: ENSMUSG00000052751
AA Change: Q593L
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
52 |
72 |
3.47e1 |
SMART |
|
ZnF_C2H2
|
80 |
102 |
5.81e-2 |
SMART |
|
ZnF_C2H2
|
111 |
133 |
5.5e-3 |
SMART |
|
ZnF_C2H2
|
140 |
160 |
1.16e1 |
SMART |
|
ZnF_C2H2
|
172 |
194 |
3.89e-3 |
SMART |
|
low complexity region
|
196 |
224 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
229 |
251 |
1.67e-2 |
SMART |
|
ZnF_C2H2
|
257 |
279 |
4.94e-5 |
SMART |
|
ZnF_C2H2
|
285 |
307 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
353 |
375 |
4.72e-2 |
SMART |
|
ZnF_C2H2
|
381 |
403 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
409 |
431 |
1.79e-2 |
SMART |
|
ZnF_C2H2
|
437 |
459 |
4.24e-4 |
SMART |
|
ZnF_C2H2
|
465 |
487 |
6.52e-5 |
SMART |
|
ZnF_C2H2
|
493 |
515 |
2.61e-4 |
SMART |
|
ZnF_C2H2
|
521 |
543 |
1.45e-2 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000135151
AA Change: Q596L
PolyPhen 2
Score 0.873 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000118890
Gene: ENSMUSG00000052751
AA Change: Q596L
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
52 |
72 |
3.47e1 |
SMART |
|
ZnF_C2H2
|
80 |
102 |
5.81e-2 |
SMART |
|
ZnF_C2H2
|
111 |
133 |
5.5e-3 |
SMART |
|
ZnF_C2H2
|
140 |
160 |
1.16e1 |
SMART |
|
ZnF_C2H2
|
172 |
194 |
3.89e-3 |
SMART |
|
low complexity region
|
196 |
224 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
229 |
251 |
1.67e-2 |
SMART |
|
ZnF_C2H2
|
257 |
279 |
4.94e-5 |
SMART |
|
Pfam:zf-C2H2_6
|
284 |
300 |
1.4e-1 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000154010
|
| SMART Domains |
Protein: ENSMUSP00000121975
Gene: ENSMUSG00000052751
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
52 |
72 |
3.47e1 |
SMART |
|
ZnF_C2H2
|
80 |
102 |
5.81e-2 |
SMART |
|
ZnF_C2H2
|
111 |
133 |
5.5e-3 |
SMART |
|
ZnF_C2H2
|
140 |
160 |
1.16e1 |
SMART |
|
ZnF_C2H2
|
172 |
194 |
3.89e-3 |
SMART |
|
low complexity region
|
196 |
224 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
229 |
251 |
1.67e-2 |
SMART |
|
ZnF_C2H2
|
257 |
279 |
4.94e-5 |
SMART |
|
ZnF_C2H2
|
285 |
307 |
5.21e-4 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000163452
AA Change: Q540L
PolyPhen 2
Score 0.761 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000132365
Gene: ENSMUSG00000052751
AA Change: Q540L
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
52 |
72 |
3.47e1 |
SMART |
|
ZnF_C2H2
|
80 |
102 |
5.81e-2 |
SMART |
|
ZnF_C2H2
|
111 |
133 |
5.5e-3 |
SMART |
|
ZnF_C2H2
|
140 |
160 |
1.16e1 |
SMART |
|
ZnF_C2H2
|
172 |
194 |
3.89e-3 |
SMART |
|
low complexity region
|
196 |
224 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
229 |
251 |
1.67e-2 |
SMART |
|
ZnF_C2H2
|
257 |
279 |
4.94e-5 |
SMART |
|
ZnF_C2H2
|
285 |
307 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
353 |
375 |
4.72e-2 |
SMART |
|
ZnF_C2H2
|
381 |
403 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
409 |
431 |
1.79e-2 |
SMART |
|
ZnF_C2H2
|
437 |
459 |
4.24e-4 |
SMART |
|
ZnF_C2H2
|
465 |
487 |
6.52e-5 |
SMART |
|
ZnF_C2H2
|
493 |
515 |
2.61e-4 |
SMART |
|
ZnF_C2H2
|
521 |
543 |
1.45e-2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000204095
|
| SMART Domains |
Protein: ENSMUSP00000145192
Gene: ENSMUSG00000007216
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
86 |
102 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
104 |
126 |
7.9e-4 |
SMART |
|
ZnF_C2H2
|
132 |
154 |
1.69e-3 |
SMART |
|
ZnF_C2H2
|
160 |
182 |
2.36e-2 |
SMART |
|
ZnF_C2H2
|
188 |
210 |
4.11e-2 |
SMART |
|
ZnF_C2H2
|
279 |
301 |
1.84e-4 |
SMART |
|
ZnF_C2H2
|
307 |
329 |
4.94e-5 |
SMART |
|
ZnF_C2H2
|
335 |
357 |
2.95e-3 |
SMART |
|
ZnF_C2H2
|
364 |
386 |
1.36e-2 |
SMART |
|
ZnF_C2H2
|
446 |
468 |
1.3e-4 |
SMART |
|
ZnF_C2H2
|
474 |
496 |
2.12e-4 |
SMART |
|
ZnF_C2H2
|
502 |
524 |
5.5e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000204121
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000204521
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.4%
- 20x: 98.4%
|
| Validation Efficiency |
99% (71/72) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele improves in insulin sensitivity and glucose metabolism in Leprdb homozygotes. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 69 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A730071L15Rik |
G |
A |
11: 6,150,439 (GRCm39) |
W137* |
probably null |
Het |
| Acads |
G |
A |
5: 115,250,417 (GRCm39) |
T169I |
probably benign |
Het |
| Adgrg7 |
T |
A |
16: 56,570,787 (GRCm39) |
N414Y |
probably damaging |
Het |
| Ankrd35 |
T |
A |
3: 96,577,742 (GRCm39) |
S6T |
probably damaging |
Het |
| Armc3 |
A |
G |
2: 19,206,630 (GRCm39) |
|
probably null |
Het |
| Atp9a |
C |
A |
2: 168,496,140 (GRCm39) |
V555F |
possibly damaging |
Het |
| Bltp1 |
A |
G |
3: 37,075,630 (GRCm39) |
Y3610C |
probably damaging |
Het |
| Cars2 |
C |
T |
8: 11,566,198 (GRCm39) |
V443I |
probably benign |
Het |
| Cblc |
A |
G |
7: 19,526,821 (GRCm39) |
L137P |
probably damaging |
Het |
| Ccdc198 |
T |
C |
14: 49,481,270 (GRCm39) |
|
probably null |
Het |
| Cdk5r1 |
T |
A |
11: 80,369,021 (GRCm39) |
C229* |
probably null |
Het |
| Cep85 |
C |
G |
4: 133,883,167 (GRCm39) |
A241P |
probably benign |
Het |
| Cfap54 |
T |
C |
10: 92,710,877 (GRCm39) |
Y2728C |
unknown |
Het |
| Ckap5 |
T |
A |
2: 91,400,597 (GRCm39) |
W650R |
probably damaging |
Het |
| Cnot11 |
C |
T |
1: 39,579,148 (GRCm39) |
Q12* |
probably null |
Het |
| Commd6 |
A |
T |
14: 101,874,534 (GRCm39) |
D19E |
probably damaging |
Het |
| Crygc |
C |
T |
1: 65,112,361 (GRCm39) |
G71D |
possibly damaging |
Het |
| Cstf3 |
A |
G |
2: 104,486,076 (GRCm39) |
K439E |
probably benign |
Het |
| Cyp11b2 |
G |
T |
15: 74,727,340 (GRCm39) |
H114N |
probably benign |
Het |
| Cyp2d40 |
T |
C |
15: 82,645,687 (GRCm39) |
D106G |
probably benign |
Het |
| Dhx8 |
T |
A |
11: 101,655,618 (GRCm39) |
V1117E |
probably damaging |
Het |
| Duoxa1 |
G |
T |
2: 122,134,462 (GRCm39) |
L219I |
probably damaging |
Het |
| Dynap |
A |
T |
18: 70,374,253 (GRCm39) |
I91N |
probably damaging |
Het |
| Elfn1 |
G |
T |
5: 139,958,900 (GRCm39) |
G635W |
probably damaging |
Het |
| Fan1 |
A |
T |
7: 64,014,377 (GRCm39) |
I618N |
probably damaging |
Het |
| Fras1 |
A |
G |
5: 96,876,410 (GRCm39) |
D2381G |
probably damaging |
Het |
| Fxyd6 |
T |
A |
9: 45,302,851 (GRCm39) |
|
probably null |
Het |
| Gpr137b |
A |
T |
13: 13,538,094 (GRCm39) |
W286R |
probably damaging |
Het |
| Gpsm3 |
A |
T |
17: 34,809,536 (GRCm39) |
|
probably null |
Het |
| Has1 |
C |
T |
17: 18,064,122 (GRCm39) |
V506I |
probably benign |
Het |
| Hoxd10 |
T |
A |
2: 74,522,616 (GRCm39) |
V98D |
probably benign |
Het |
| Htr2b |
T |
A |
1: 86,027,615 (GRCm39) |
D297V |
probably benign |
Het |
| Hydin |
G |
C |
8: 111,265,007 (GRCm39) |
R2730P |
probably benign |
Het |
| I830077J02Rik |
T |
C |
3: 105,833,830 (GRCm39) |
N109D |
possibly damaging |
Het |
| Igf2r |
A |
T |
17: 12,922,263 (GRCm39) |
F1284I |
probably damaging |
Het |
| Ildr2 |
C |
G |
1: 166,098,144 (GRCm39) |
D167E |
probably damaging |
Het |
| Ipo9 |
T |
C |
1: 135,314,046 (GRCm39) |
D949G |
probably benign |
Het |
| Itga10 |
T |
C |
3: 96,564,030 (GRCm39) |
F895L |
probably damaging |
Het |
| Itpr1 |
A |
G |
6: 108,365,153 (GRCm39) |
N27S |
probably damaging |
Het |
| Klra4 |
C |
A |
6: 130,042,162 (GRCm39) |
R35L |
probably benign |
Het |
| Map3k2 |
T |
A |
18: 32,359,682 (GRCm39) |
C512S |
probably benign |
Het |
| Mertk |
A |
G |
2: 128,601,150 (GRCm39) |
|
probably null |
Het |
| Mgat2 |
T |
A |
12: 69,232,407 (GRCm39) |
I327N |
probably damaging |
Het |
| Mogat1 |
T |
C |
1: 78,499,496 (GRCm39) |
I59T |
probably damaging |
Het |
| Mrpl2 |
A |
T |
17: 46,958,382 (GRCm39) |
M55L |
probably benign |
Het |
| Nxpe3 |
T |
C |
16: 55,664,685 (GRCm39) |
M512V |
possibly damaging |
Het |
| Pcdh15 |
T |
C |
10: 74,286,052 (GRCm39) |
L769P |
probably damaging |
Het |
| Pcmtd2 |
T |
G |
2: 181,486,231 (GRCm39) |
V117G |
probably damaging |
Het |
| Pdia2 |
A |
T |
17: 26,415,578 (GRCm39) |
|
probably null |
Het |
| Rnf213 |
C |
T |
11: 119,340,692 (GRCm39) |
T3517I |
probably benign |
Het |
| Rxfp2 |
A |
T |
5: 149,942,210 (GRCm39) |
|
probably benign |
Het |
| Skint8 |
T |
C |
4: 111,785,968 (GRCm39) |
L138P |
probably damaging |
Het |
| Slc35a3 |
T |
A |
3: 116,506,417 (GRCm39) |
Q5L |
probably null |
Het |
| Stab2 |
T |
A |
10: 86,778,054 (GRCm39) |
N758I |
probably damaging |
Het |
| Sulf1 |
T |
A |
1: 12,908,658 (GRCm39) |
I557N |
probably damaging |
Het |
| Tbc1d8 |
T |
C |
1: 39,428,455 (GRCm39) |
I497V |
possibly damaging |
Het |
| Ticam2 |
A |
C |
18: 46,693,998 (GRCm39) |
S30A |
probably benign |
Het |
| Timp3 |
T |
C |
10: 86,181,638 (GRCm39) |
S170P |
possibly damaging |
Het |
| Top1mt |
C |
T |
15: 75,547,973 (GRCm39) |
E38K |
probably benign |
Het |
| Tpp1 |
G |
A |
7: 105,398,171 (GRCm39) |
L331F |
probably damaging |
Het |
| Trpm7 |
A |
T |
2: 126,654,941 (GRCm39) |
D1332E |
probably benign |
Het |
| Ttc23 |
A |
G |
7: 67,319,476 (GRCm39) |
E112G |
possibly damaging |
Het |
| Ttn |
T |
C |
2: 76,715,296 (GRCm39) |
|
probably benign |
Het |
| Ttn |
T |
A |
2: 76,726,934 (GRCm39) |
|
probably benign |
Het |
| Ubr3 |
T |
A |
2: 69,850,969 (GRCm39) |
C1796S |
probably damaging |
Het |
| Ugt2b34 |
C |
T |
5: 87,040,675 (GRCm39) |
V416I |
probably benign |
Het |
| Uqcrb |
A |
G |
13: 67,048,827 (GRCm39) |
|
probably benign |
Het |
| Vps26b |
A |
G |
9: 26,921,760 (GRCm39) |
L255P |
probably benign |
Het |
| Wdr59 |
A |
G |
8: 112,223,512 (GRCm39) |
V154A |
probably damaging |
Het |
|
| Other mutations in Repin1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01100:Repin1
|
APN |
6 |
48,573,839 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01103:Repin1
|
APN |
6 |
48,574,887 (GRCm39) |
intron |
probably benign |
|
|
IGL02027:Repin1
|
APN |
6 |
48,573,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02143:Repin1
|
APN |
6 |
48,574,055 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0395:Repin1
|
UTSW |
6 |
48,574,459 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1233:Repin1
|
UTSW |
6 |
48,574,768 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R1743:Repin1
|
UTSW |
6 |
48,574,684 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2259:Repin1
|
UTSW |
6 |
48,573,464 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4509:Repin1
|
UTSW |
6 |
48,573,460 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5008:Repin1
|
UTSW |
6 |
48,573,542 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5009:Repin1
|
UTSW |
6 |
48,571,779 (GRCm39) |
intron |
probably benign |
|
|
R5425:Repin1
|
UTSW |
6 |
48,573,365 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5829:Repin1
|
UTSW |
6 |
48,571,766 (GRCm39) |
intron |
probably benign |
|
|
R6350:Repin1
|
UTSW |
6 |
48,574,562 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6854:Repin1
|
UTSW |
6 |
48,570,825 (GRCm39) |
intron |
probably benign |
|
|
R7067:Repin1
|
UTSW |
6 |
48,574,850 (GRCm39) |
nonsense |
probably null |
|
|
R7636:Repin1
|
UTSW |
6 |
48,573,299 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7699:Repin1
|
UTSW |
6 |
48,574,756 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7700:Repin1
|
UTSW |
6 |
48,574,756 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7747:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R7748:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R7781:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R7815:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R7820:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R7869:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R7988:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R7991:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8078:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8079:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8080:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8088:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8089:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8130:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8131:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8324:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8325:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8342:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8411:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8488:Repin1
|
UTSW |
6 |
48,570,952 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8542:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8543:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8544:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8697:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8699:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8701:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8702:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8731:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8732:Repin1
|
UTSW |
6 |
48,574,279 (GRCm39) |
nonsense |
probably null |
|
|
R8780:Repin1
|
UTSW |
6 |
48,574,073 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8879:Repin1
|
UTSW |
6 |
48,574,367 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9049:Repin1
|
UTSW |
6 |
48,574,646 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9465:Repin1
|
UTSW |
6 |
48,571,877 (GRCm39) |
missense |
probably benign |
0.18 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCAGTCAGAAGTCCAACCTGG -3'
(R):5'- ATGGGTTCCCTGGATACCTAG -3'
Sequencing Primer
(F):5'- TCAGAAGTCCAACCTGGTGTCC -3'
(R):5'- TTCCCTGGATACCTAGGGGAAAGTC -3'
|
| Posted On |
2018-10-18 |
Incidental Mutation