Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01466:Ccdc152'

88118

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ccdc152

Ensembl Gene

ENSMUSG00000091119

Gene Name

coiled-coil domain containing 152

Synonyms

ENSMUSG00000071814

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.201) question?

Stock #

IGL01466

Quality Score

Status

Chromosome

Chromosomal Location

3309552-3333008 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to G at 3323329 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000153740 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000165386] [ENSMUST00000226261] [ENSMUST00000228405]

AlphaFold

E9PX14

Predicted Effect

probably benign
Transcript: ENSMUST00000165386

SMART Domains

Protein: ENSMUSP00000129305
Gene: ENSMUSG00000091119

Domain	Start	End	E-Value	Type
coiled coil region	76	186	N/A	INTRINSIC
coiled coil region	211	250	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000226261

Predicted Effect

probably benign
Transcript: ENSMUST00000228405

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 20 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acr	A	G	15: 89,458,197 (GRCm39)	N293D	probably benign	Het
Ankrd49	A	G	9: 14,692,645 (GRCm39)	L173P	probably damaging	Het
Cdh3	G	T	8: 107,263,227 (GRCm39)	R92L	possibly damaging	Het
Dnajc10	A	T	2: 80,151,631 (GRCm39)	R137S	probably benign	Het
Htra2	A	G	6: 83,031,304 (GRCm39)	L35P	probably damaging	Het
Il23r	A	T	6: 67,403,626 (GRCm39)	M425K	probably benign	Het
Nfkb2	G	T	19: 46,296,455 (GRCm39)	R241L	probably damaging	Het
Nup205	A	G	6: 35,176,894 (GRCm39)	D630G	probably benign	Het
Or1j15	T	A	2: 36,458,754 (GRCm39)	L48H	probably damaging	Het
Peli2	T	C	14: 48,493,914 (GRCm39)	Y379H	probably damaging	Het
Plekhg6	G	T	6: 125,349,587 (GRCm39)		probably benign	Het
Samd14	G	T	11: 94,914,081 (GRCm39)		probably benign	Het
Setd7	A	T	3: 51,428,730 (GRCm39)	*367R	probably null	Het
Slc26a8	A	G	17: 28,873,922 (GRCm39)	V355A	probably benign	Het
Slc46a2	T	A	4: 59,911,926 (GRCm39)	K429*	probably null	Het
Styxl2	T	G	1: 165,928,073 (GRCm39)	D513A	probably damaging	Het
Tspan32	T	C	7: 142,568,691 (GRCm39)		probably benign	Het
Unc80	T	C	1: 66,661,645 (GRCm39)	V1690A	probably benign	Het
Ush2a	C	A	1: 188,643,819 (GRCm39)	Q4394K	probably benign	Het
Zfp277	C	A	12: 40,428,825 (GRCm39)	G174V	probably benign	Het

Other mutations in Ccdc152

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01543:Ccdc152	APN	15	3,327,606 (GRCm39)	missense	possibly damaging	0.91
R0622:Ccdc152	UTSW	15	3,327,660 (GRCm39)	missense	probably damaging	0.96
R1605:Ccdc152	UTSW	15	3,327,603 (GRCm39)	missense	probably damaging	0.99
R2875:Ccdc152	UTSW	15	3,327,663 (GRCm39)	missense	probably damaging	1.00
R2876:Ccdc152	UTSW	15	3,327,663 (GRCm39)	missense	probably damaging	1.00
R4990:Ccdc152	UTSW	15	3,330,639 (GRCm39)	missense	probably benign	0.00
R5114:Ccdc152	UTSW	15	3,312,319 (GRCm39)	missense	probably damaging	0.99
R5732:Ccdc152	UTSW	15	3,321,860 (GRCm39)	critical splice donor site	probably null
R6336:Ccdc152	UTSW	15	3,330,611 (GRCm39)	missense	probably damaging	1.00
R6704:Ccdc152	UTSW	15	3,310,195 (GRCm39)	missense	probably damaging	1.00
R7593:Ccdc152	UTSW	15	3,310,137 (GRCm39)	missense	probably damaging	1.00
R8300:Ccdc152	UTSW	15	3,327,634 (GRCm39)	missense	probably benign	0.00
R9061:Ccdc152	UTSW	15	3,330,643 (GRCm39)	missense	probably damaging	1.00

Posted On

2013-11-18