Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01528:Vmn1r7'

89626

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r7

Ensembl Gene

ENSMUSG00000093696

Gene Name

vomeronasal 1 receptor 7

Synonyms

V1rc31, Gm5568

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.121) question?

Stock #

IGL01528

Quality Score

Status

Chromosome

Chromosomal Location

57001323-57002258 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 57001532 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Methionine to Leucine at position 243 (M243L)

Ref Sequence

ENSEMBL: ENSMUSP00000135571 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000176252]

AlphaFold

E9Q8T0

Predicted Effect

probably benign
Transcript: ENSMUST00000176252
AA Change: M243L

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000135571
Gene: ENSMUSG00000093696
AA Change: M243L

Domain	Start	End	E-Value	Type
Pfam:V1R	28	293	1.1e-59	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 37 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
AB124611	T	A	9: 21,451,190 (GRCm39)		probably benign	Het
Cdc45	A	G	16: 18,630,311 (GRCm39)	F2S	probably damaging	Het
Cdon	A	G	9: 35,381,403 (GRCm39)	R598G	possibly damaging	Het
Cemip2	T	C	19: 21,812,909 (GRCm39)	V1038A	possibly damaging	Het
Dusp22	C	T	13: 30,889,611 (GRCm39)	T64I	probably benign	Het
Gfer	T	A	17: 24,914,903 (GRCm39)	T47S	probably benign	Het
Gfra2	T	C	14: 71,203,738 (GRCm39)	S296P	possibly damaging	Het
Gjb2	G	A	14: 57,338,125 (GRCm39)	L28F	probably damaging	Het
Gm17782	A	G	17: 36,472,682 (GRCm39)		probably benign	Het
Gm2832	T	C	14: 41,003,670 (GRCm39)	V167A	unknown	Het
Gpr155	A	G	2: 73,192,767 (GRCm39)		probably null	Het
Gpr45	A	G	1: 43,072,383 (GRCm39)	H342R	probably benign	Het
Gsdmd	A	T	15: 75,735,354 (GRCm39)	T33S	possibly damaging	Het
Hal	T	A	10: 93,333,455 (GRCm39)	L341Q	probably damaging	Het
Igfbp7	T	G	5: 77,499,179 (GRCm39)	D273A	probably damaging	Het
Kdm2a	T	C	19: 4,393,083 (GRCm39)	D424G	probably benign	Het
Kif13a	C	T	13: 47,018,313 (GRCm39)		probably benign	Het
Krt35	A	T	11: 99,985,420 (GRCm39)	L207Q	probably damaging	Het
Lrp1b	A	T	2: 40,809,194 (GRCm39)	D2572E	probably damaging	Het
Lrp2	A	G	2: 69,322,804 (GRCm39)	V1848A	probably damaging	Het
Myo9a	T	C	9: 59,686,957 (GRCm39)	Y21H	probably damaging	Het
Ncan	G	T	8: 70,562,731 (GRCm39)	A509E	probably benign	Het
Or2q1	T	C	6: 42,795,208 (GRCm39)	S268P	probably damaging	Het
Pde11a	G	A	2: 76,025,300 (GRCm39)		probably benign	Het
Phf19	G	T	2: 34,787,119 (GRCm39)	D448E	probably damaging	Het
Ptprj	A	T	2: 90,282,488 (GRCm39)	V799D	probably damaging	Het
Rpgrip1	T	A	14: 52,349,634 (GRCm39)	Y7*	probably null	Het
Sema3c	A	G	5: 17,919,413 (GRCm39)	H483R	probably benign	Het
Slc4a11	A	G	2: 130,527,328 (GRCm39)		probably benign	Het
St3gal1	C	A	15: 66,984,466 (GRCm39)	R103L	probably benign	Het
Tet2	A	T	3: 133,186,059 (GRCm39)	V1126E	possibly damaging	Het
Tmem117	A	T	15: 94,992,545 (GRCm39)	I402L	probably benign	Het
Ttc28	T	A	5: 111,249,826 (GRCm39)		probably benign	Het
Ttn	A	T	2: 76,702,182 (GRCm39)		probably benign	Het
Wnt1	G	T	15: 98,689,714 (GRCm39)	W167L	probably damaging	Het
Zfp553	G	T	7: 126,835,387 (GRCm39)	S314I	probably damaging	Het
Zranb2	T	C	3: 157,250,602 (GRCm39)		probably benign	Het

Other mutations in Vmn1r7

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01382:Vmn1r7	APN	6	57,001,708 (GRCm39)	missense	probably damaging	1.00
IGL02024:Vmn1r7	APN	6	57,001,874 (GRCm39)	missense	probably benign	0.01
IGL02234:Vmn1r7	APN	6	57,001,537 (GRCm39)	missense	probably damaging	0.98
IGL02610:Vmn1r7	APN	6	57,002,037 (GRCm39)	missense	probably benign	0.01
IGL02691:Vmn1r7	APN	6	57,001,373 (GRCm39)	missense	probably benign	0.05
R0529:Vmn1r7	UTSW	6	57,001,450 (GRCm39)	missense	possibly damaging	0.78
R0548:Vmn1r7	UTSW	6	57,002,066 (GRCm39)	missense	probably damaging	0.96
R1254:Vmn1r7	UTSW	6	57,001,772 (GRCm39)	missense	probably damaging	1.00
R1279:Vmn1r7	UTSW	6	57,001,934 (GRCm39)	missense	possibly damaging	0.63
R1582:Vmn1r7	UTSW	6	57,002,143 (GRCm39)	missense	probably damaging	1.00
R1973:Vmn1r7	UTSW	6	57,002,011 (GRCm39)	missense	probably benign	0.00
R1991:Vmn1r7	UTSW	6	57,001,853 (GRCm39)	missense	probably benign	0.37
R2160:Vmn1r7	UTSW	6	57,001,879 (GRCm39)	missense	probably damaging	0.97
R3546:Vmn1r7	UTSW	6	57,001,834 (GRCm39)	missense	possibly damaging	0.80
R3547:Vmn1r7	UTSW	6	57,001,834 (GRCm39)	missense	possibly damaging	0.80
R5901:Vmn1r7	UTSW	6	57,001,591 (GRCm39)	missense	probably damaging	1.00
R6294:Vmn1r7	UTSW	6	57,001,404 (GRCm39)	missense	probably benign	0.00
R7063:Vmn1r7	UTSW	6	57,001,418 (GRCm39)	missense	possibly damaging	0.63
R7192:Vmn1r7	UTSW	6	57,001,452 (GRCm39)	missense	probably benign	0.00
R7647:Vmn1r7	UTSW	6	57,002,255 (GRCm39)	missense	probably benign	0.01
R7781:Vmn1r7	UTSW	6	57,001,553 (GRCm39)	missense	probably benign	0.03
R9457:Vmn1r7	UTSW	6	57,001,508 (GRCm39)	missense	probably damaging	0.97

Posted On

2013-12-03