Incidental Mutation 'IGL01561:Fpr-rs3'
| ID |
90837 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Fpr-rs3
|
| Ensembl Gene |
ENSMUSG00000060701 |
| Gene Name |
formyl peptide receptor, related sequence 3 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.098)
|
| Stock # |
IGL01561
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
17 |
| Chromosomal Location |
20844108-20845139 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 20844859 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Aspartic acid
at position 94
(G94D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000071179
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071189]
|
| AlphaFold |
O88537 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000071189
AA Change: G94D
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000071179
Gene: ENSMUSG00000060701
AA Change: G94D
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:7tm_1
|
43 |
297 |
1.8e-36 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 27 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aebp1 |
G |
A |
11: 5,821,349 (GRCm39) |
D583N |
probably damaging |
Het |
| Aoah |
G |
T |
13: 21,189,264 (GRCm39) |
D496Y |
probably damaging |
Het |
| Aoah |
T |
C |
13: 21,089,905 (GRCm39) |
|
probably benign |
Het |
| Cdh10 |
G |
T |
15: 19,000,012 (GRCm39) |
A486S |
possibly damaging |
Het |
| Cers2 |
A |
T |
3: 95,229,472 (GRCm39) |
|
probably null |
Het |
| Clec4a4 |
T |
A |
6: 123,000,975 (GRCm39) |
C229* |
probably null |
Het |
| Col15a1 |
T |
C |
4: 47,312,118 (GRCm39) |
V1311A |
possibly damaging |
Het |
| Fsd1 |
T |
A |
17: 56,302,363 (GRCm39) |
M269K |
probably benign |
Het |
| Golga2 |
A |
G |
2: 32,186,689 (GRCm39) |
M73V |
probably benign |
Het |
| Gusb |
A |
T |
5: 130,026,927 (GRCm39) |
V388E |
probably damaging |
Het |
| Heg1 |
A |
G |
16: 33,587,038 (GRCm39) |
N1267S |
probably benign |
Het |
| Htra4 |
A |
C |
8: 25,523,587 (GRCm39) |
I326S |
probably damaging |
Het |
| Klhl33 |
T |
C |
14: 51,128,888 (GRCm39) |
I780M |
probably benign |
Het |
| Mertk |
T |
C |
2: 128,578,556 (GRCm39) |
S181P |
probably damaging |
Het |
| Mpdz |
T |
C |
4: 81,202,851 (GRCm39) |
H1882R |
probably damaging |
Het |
| Muc13 |
A |
G |
16: 33,626,411 (GRCm39) |
K317E |
possibly damaging |
Het |
| Nek3 |
A |
G |
8: 22,619,472 (GRCm39) |
F440S |
probably damaging |
Het |
| Nrxn2 |
G |
A |
19: 6,540,172 (GRCm39) |
R831H |
probably damaging |
Het |
| Or10w1 |
T |
C |
19: 13,632,269 (GRCm39) |
F159L |
probably benign |
Het |
| Or1q1 |
T |
A |
2: 36,886,955 (GRCm39) |
F44L |
probably benign |
Het |
| Or7e173 |
T |
C |
9: 19,938,818 (GRCm39) |
M139V |
probably benign |
Het |
| Palmd |
A |
T |
3: 116,717,742 (GRCm39) |
S252T |
probably damaging |
Het |
| Piezo2 |
C |
A |
18: 63,257,685 (GRCm39) |
M344I |
probably benign |
Het |
| Pygo1 |
T |
A |
9: 72,852,570 (GRCm39) |
N252K |
probably damaging |
Het |
| Rhobtb1 |
A |
G |
10: 69,106,221 (GRCm39) |
Q262R |
probably benign |
Het |
| Xpo1 |
T |
C |
11: 23,232,706 (GRCm39) |
Y409H |
possibly damaging |
Het |
| Zan |
T |
A |
5: 137,462,128 (GRCm39) |
E1017V |
unknown |
Het |
|
| Other mutations in Fpr-rs3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02230:Fpr-rs3
|
APN |
17 |
20,844,190 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02503:Fpr-rs3
|
APN |
17 |
20,844,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02809:Fpr-rs3
|
APN |
17 |
20,844,225 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03212:Fpr-rs3
|
APN |
17 |
20,844,121 (GRCm39) |
missense |
probably benign |
0.00 |
|
I2288:Fpr-rs3
|
UTSW |
17 |
20,844,757 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0318:Fpr-rs3
|
UTSW |
17 |
20,844,410 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0565:Fpr-rs3
|
UTSW |
17 |
20,844,283 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1005:Fpr-rs3
|
UTSW |
17 |
20,844,346 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1986:Fpr-rs3
|
UTSW |
17 |
20,844,103 (GRCm39) |
splice site |
probably null |
|
|
R3941:Fpr-rs3
|
UTSW |
17 |
20,845,111 (GRCm39) |
missense |
probably benign |
0.42 |
|
R4297:Fpr-rs3
|
UTSW |
17 |
20,845,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4809:Fpr-rs3
|
UTSW |
17 |
20,844,683 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4959:Fpr-rs3
|
UTSW |
17 |
20,844,211 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4973:Fpr-rs3
|
UTSW |
17 |
20,844,211 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R5116:Fpr-rs3
|
UTSW |
17 |
20,844,562 (GRCm39) |
missense |
probably benign |
0.12 |
|
R5356:Fpr-rs3
|
UTSW |
17 |
20,844,596 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5394:Fpr-rs3
|
UTSW |
17 |
20,844,470 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5779:Fpr-rs3
|
UTSW |
17 |
20,844,488 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6091:Fpr-rs3
|
UTSW |
17 |
20,844,532 (GRCm39) |
missense |
probably benign |
0.30 |
|
R6389:Fpr-rs3
|
UTSW |
17 |
20,844,230 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6860:Fpr-rs3
|
UTSW |
17 |
20,844,560 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7578:Fpr-rs3
|
UTSW |
17 |
20,844,293 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8153:Fpr-rs3
|
UTSW |
17 |
20,844,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8711:Fpr-rs3
|
UTSW |
17 |
20,844,554 (GRCm39) |
missense |
probably benign |
|
|
R8768:Fpr-rs3
|
UTSW |
17 |
20,844,944 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0018:Fpr-rs3
|
UTSW |
17 |
20,844,899 (GRCm39) |
missense |
probably benign |
0.30 |
|
| Posted On |
2013-12-09 |
Incidental Mutation