Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00658:Gm904'

11030

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm904

Ensembl Gene

ENSMUSG00000096641

Gene Name

predicted gene 904

Synonyms

LOC380845, LOC382165

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.061) question?

Stock #

IGL00658

Quality Score

Status

Chromosome

Chromosomal Location

50797235-50799874 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to T at 50798758 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Alanine to Serine at position 76 (A76S)

Ref Sequence

ENSEMBL: ENSMUSP00000097119 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000099519]

AlphaFold

Q3V2L5

Predicted Effect

possibly damaging
Transcript: ENSMUST00000099519
AA Change: A76S

PolyPhen 2 Score 0.906 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000097119
Gene: ENSMUSG00000096641
AA Change: A76S

Domain	Start	End	E-Value	Type
transmembrane domain	23	45	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000191999

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000192039

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 12 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adam26a	T	A	8: 44,021,940 (GRCm39)	M517L	probably benign	Het
Alms1	A	G	6: 85,605,943 (GRCm39)	E2531G	probably damaging	Het
Apob	A	T	12: 8,059,471 (GRCm39)	H2618L	probably benign	Het
Cfap69	A	T	5: 5,675,857 (GRCm39)	D252E	probably damaging	Het
Kansl1	G	A	11: 104,248,352 (GRCm39)	T534I	probably benign	Het
Ripor1	C	T	8: 106,344,749 (GRCm39)		probably benign	Het
Scn1a	T	C	2: 66,116,382 (GRCm39)	Q1439R	probably damaging	Het
Serpina3i	T	A	12: 104,231,429 (GRCm39)	V22D	possibly damaging	Het
Slc22a2	A	T	17: 12,834,202 (GRCm39)	D490V	probably benign	Het
Tlcd5	T	C	9: 43,024,786 (GRCm39)	I57V	probably benign	Het
Ttn	G	A	2: 76,727,616 (GRCm39)		probably benign	Het
Vegfc	T	C	8: 54,609,983 (GRCm39)		probably benign	Het

Other mutations in Gm904

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R1939:Gm904	UTSW	13	50,798,772 (GRCm39)	critical splice donor site	probably null
R4590:Gm904	UTSW	13	50,799,285 (GRCm39)	nonsense	probably null
R4900:Gm904	UTSW	13	50,799,325 (GRCm39)	missense	possibly damaging	0.59
R7239:Gm904	UTSW	13	50,799,287 (GRCm39)	missense	probably benign	0.00
R8004:Gm904	UTSW	13	50,799,343 (GRCm39)	critical splice donor site	probably null
R8400:Gm904	UTSW	13	50,797,453 (GRCm39)	missense	probably damaging	1.00
Z1088:Gm904	UTSW	13	50,799,298 (GRCm39)	missense	probably damaging	1.00

Posted On

2012-12-06