Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01957:Gm94'

181127

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm94

Ensembl Gene

ENSMUSG00000071858

Gene Name

predicted gene 94

Synonyms

LOC225443

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL01957

Quality Score

Status

Chromosome

Chromosomal Location

43910261-43925943 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 43917746 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 40 (S40P)

Ref Sequence

ENSEMBL: ENSMUSP00000094321 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000096570]

AlphaFold

Q3V2D2

Predicted Effect

probably damaging
Transcript: ENSMUST00000096570
AA Change: S40P

PolyPhen 2 Score 0.966 (Sensitivity: 0.77; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000094321
Gene: ENSMUSG00000071858
AA Change: S40P

Domain	Start	End	E-Value	Type
Pfam:DUF4576	1	90	1.3e-50	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 22 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
6030469F06Rik	T	C	12: 31,235,042 (GRCm39)		noncoding transcript	Het
Cops3	A	G	11: 59,712,217 (GRCm39)		probably benign	Het
Cyth2	A	T	7: 45,457,805 (GRCm39)	Y304N	probably benign	Het
Dhx8	A	G	11: 101,645,652 (GRCm39)	N837S	possibly damaging	Het
Evpl	A	G	11: 116,114,048 (GRCm39)	L1214P	probably damaging	Het
Gpm6a	A	T	8: 55,503,212 (GRCm39)	M154L	probably benign	Het
Ipo13	A	G	4: 117,761,078 (GRCm39)	S547P	probably damaging	Het
Mfsd14b	A	C	13: 65,234,907 (GRCm39)	V90G	possibly damaging	Het
Mfsd4b4	A	T	10: 39,768,025 (GRCm39)	M356K	probably damaging	Het
Msh6	T	G	17: 88,292,519 (GRCm39)	F425V	possibly damaging	Het
Or4k15c	T	C	14: 50,321,737 (GRCm39)	T134A	probably benign	Het
Or52m2	A	T	7: 102,263,546 (GRCm39)	L217I	probably damaging	Het
Or6c215	A	G	10: 129,638,119 (GRCm39)	Y92H	probably damaging	Het
Ptk2	T	C	15: 73,114,322 (GRCm39)	I679V	probably benign	Het
Rtel1	T	C	2: 180,991,106 (GRCm39)		probably benign	Het
Sema3d	T	A	5: 12,613,282 (GRCm39)	V453E	probably damaging	Het
Spata31e2	C	T	1: 26,724,340 (GRCm39)	C280Y	probably damaging	Het
Syk	C	A	13: 52,785,776 (GRCm39)	D327E	probably benign	Het
Triobp	G	A	15: 78,856,847 (GRCm39)		probably null	Het
Tubgcp5	G	A	7: 55,468,505 (GRCm39)	E667K	probably damaging	Het
Vmn2r129	C	T	4: 156,690,549 (GRCm39)		noncoding transcript	Het
Vmn2r76	G	T	7: 85,877,925 (GRCm39)	H491N	probably benign	Het

Other mutations in Gm94

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R0455:Gm94	UTSW	18	43,914,309 (GRCm39)	missense	possibly damaging	0.45
R4775:Gm94	UTSW	18	43,925,836 (GRCm39)	critical splice donor site	probably null
R6005:Gm94	UTSW	18	43,925,862 (GRCm39)	missense	possibly damaging	0.45
R9030:Gm94	UTSW	18	43,914,326 (GRCm39)	missense	possibly damaging	0.92

Posted On

2014-05-07