Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00660:Prelid3b'

26798

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Prelid3b

Ensembl Gene

ENSMUSG00000016257

Gene Name

PRELI domain containing 3B

Synonyms

Slmo2, 2310042G06Rik

Accession Numbers

Essential gene?

Probably essential (E-score: 0.879) question?

Stock #

IGL00660

Quality Score

Status

Chromosome

Chromosomal Location

174306884-174314734 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to C at 174307598 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000115566 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000016396] [ENSMUST00000016401] [ENSMUST00000117442] [ENSMUST00000120822] [ENSMUST00000141100]

AlphaFold

Q9CYY7

Predicted Effect

probably benign
Transcript: ENSMUST00000016396

SMART Domains

Protein: ENSMUSP00000016396
Gene: ENSMUSG00000016252

Domain	Start	End	E-Value	Type
Pfam:ATP-synt_Eps	2	51	7.8e-24	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000016401

SMART Domains

Protein: ENSMUSP00000016401
Gene: ENSMUSG00000016257

Domain	Start	End	E-Value	Type
Pfam:PRELI	15	170	3e-60	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000117442

SMART Domains

Protein: ENSMUSP00000112686
Gene: ENSMUSG00000016257

Domain	Start	End	E-Value	Type
Pfam:PRELI	1	80	1.8e-27	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000120822

SMART Domains

Protein: ENSMUSP00000113522
Gene: ENSMUSG00000016257

Domain	Start	End	E-Value	Type
Pfam:PRELI	1	80	1.8e-27	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000141100

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000147944

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000149191

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000153132

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 13 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Ap3b1	T	A	13: 94,527,371 (GRCm39)	V67D	probably damaging	Het
Calml4	A	G	9: 62,782,774 (GRCm39)	K91R	probably benign	Het
Cdin1	C	T	2: 115,607,466 (GRCm39)	A273V	possibly damaging	Het
Cracd	A	T	5: 77,002,780 (GRCm39)		probably null	Het
Dbt	T	C	3: 116,339,944 (GRCm39)	I404T	probably damaging	Het
Dync2h1	C	T	9: 7,075,797 (GRCm39)	M3023I	probably damaging	Het
E130308A19Rik	C	T	4: 59,737,743 (GRCm39)		probably benign	Het
Mcm9	A	T	10: 53,499,069 (GRCm39)	L291Q	probably damaging	Het
Mettl21e	T	C	1: 44,245,530 (GRCm39)	K239E	possibly damaging	Het
Pla2g4a	T	C	1: 149,761,954 (GRCm39)	N160D	probably benign	Het
Rab6a	T	C	7: 100,288,456 (GRCm39)		probably benign	Het
Slc7a11	T	C	3: 50,382,136 (GRCm39)	I204V	probably benign	Het
Zfp93	G	T	7: 23,975,117 (GRCm39)	K367N	probably damaging	Het

Other mutations in Prelid3b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01061:Prelid3b	APN	2	174,307,614 (GRCm39)	splice site	probably null
R0510:Prelid3b	UTSW	2	174,307,743 (GRCm39)	unclassified	probably benign
R2114:Prelid3b	UTSW	2	174,311,243 (GRCm39)	missense	probably damaging	1.00
R4688:Prelid3b	UTSW	2	174,308,592 (GRCm39)	missense	probably benign	0.17
R4735:Prelid3b	UTSW	2	174,307,683 (GRCm39)	missense	probably benign	0.00
R6973:Prelid3b	UTSW	2	174,311,155 (GRCm39)	missense	probably benign	0.10
R7684:Prelid3b	UTSW	2	174,310,210 (GRCm39)	splice site	probably null
R9337:Prelid3b	UTSW	2	174,310,161 (GRCm39)	missense	probably benign	0.26
X0063:Prelid3b	UTSW	2	174,310,095 (GRCm39)	missense	probably benign	0.03

Posted On

2013-04-17