Incidental Mutation 'IGL01326:Gm9631'
ID 74248
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm9631
Ensembl Gene
Gene Name predicted gene 9631
Synonyms
Accession Numbers
Is this an essential gene? Not available question?
Stock # IGL01326
Quality Score
Status
Chromosome 11
Chromosomal Location 121906652-121925337 bp(-) (GRCm38)
Type of Mutation missense
DNA Base Change (assembly) A to T at 121945628 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change Aspartic acid to Glutamic Acid at position 28 (D28E)
Gene Model predicted gene model for transcript(s):
AlphaFold no structure available at present
Predicted Effect possibly damaging
Transcript: ENSMUST00000130783
AA Change: D28E

PolyPhen 2 Score 0.830 (Sensitivity: 0.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000118097
Gene: ENSMUSG00000078564
AA Change: D28E

DomainStartEndE-ValueType
signal peptide 1 20 N/A INTRINSIC
KRAB 30 86 3.16e-12 SMART
ZnF_C2H2 157 177 1.69e2 SMART
ZnF_C2H2 185 207 1.36e-2 SMART
ZnF_C2H2 213 235 6.78e-3 SMART
ZnF_C2H2 241 263 2.79e-4 SMART
ZnF_C2H2 269 291 1.2e-3 SMART
ZnF_C2H2 297 319 9.88e-5 SMART
ZnF_C2H2 325 347 7.78e-3 SMART
ZnF_C2H2 353 375 1.12e-3 SMART
ZnF_C2H2 381 403 7.78e-3 SMART
ZnF_C2H2 409 431 1.5e-4 SMART
ZnF_C2H2 437 459 9.08e-4 SMART
ZnF_C2H2 465 487 1.04e-3 SMART
ZnF_C2H2 493 515 2.27e-4 SMART
ZnF_C2H2 521 543 4.17e-3 SMART
ZnF_C2H2 550 572 1.1e-2 SMART
ZnF_C2H2 578 600 3.95e-4 SMART
ZnF_C2H2 606 628 7.9e-4 SMART
ZnF_C2H2 634 656 9.73e-4 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 47 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adh1 G A 3: 138,286,911 V263M probably damaging Het
Akap13 T A 7: 75,725,348 H1909Q probably benign Het
Atg2b C T 12: 105,622,144 A1936T probably damaging Het
Atp8b3 G T 10: 80,524,376 L954M probably damaging Het
C8a T C 4: 104,856,420 Y171C probably damaging Het
Cd6 A G 19: 10,791,102 S508P probably benign Het
Cdk4 A G 10: 127,064,623 D86G possibly damaging Het
Cdr2l G T 11: 115,390,970 R100S probably benign Het
Cndp1 T A 18: 84,622,232 T283S probably benign Het
Cr2 T C 1: 195,141,221 Y1023C probably null Het
Csmd3 A G 15: 47,849,785 F1494L probably benign Het
Eng G T 2: 32,672,382 G231W probably benign Het
Erp44 A G 4: 48,218,126 V181A probably benign Het
Fam102b A G 3: 108,979,785 V299A possibly damaging Het
Fkbp15 A G 4: 62,323,250 S553P probably damaging Het
Glg1 A G 8: 111,182,573 V495A probably damaging Het
Gnptab G T 10: 88,433,065 L543F probably damaging Het
Hist1h4c A T 13: 23,698,370 I27N probably damaging Het
Khdrbs2 T G 1: 32,657,477 L329R possibly damaging Het
Kidins220 C A 12: 25,038,499 H1080Q probably damaging Het
Maml1 G A 11: 50,265,888 P487S probably benign Het
Marc2 T C 1: 184,833,851 probably benign Het
Me1 C T 9: 86,598,718 probably null Het
Morc2a C T 11: 3,681,775 R569C probably benign Het
Mrc1 A G 2: 14,266,524 Q413R probably damaging Het
Mrgprx1 A T 7: 48,021,769 C77S probably benign Het
Myo1d A T 11: 80,684,321 probably benign Het
Nr4a1 T G 15: 101,274,059 L538R probably damaging Het
Olfm1 T C 2: 28,229,552 Y385H probably damaging Het
Olfr1034 A G 2: 86,047,283 E267G probably damaging Het
Olfr1238 A T 2: 89,406,331 F249L possibly damaging Het
Pkd1 T A 17: 24,576,174 Y2278* probably null Het
Plcg2 T C 8: 117,573,999 probably benign Het
Prkdc G T 16: 15,829,692 C3660F probably benign Het
Ptpn11 T C 5: 121,143,136 D493G probably damaging Het
Rad23b T A 4: 55,383,601 F278I possibly damaging Het
Saxo2 T C 7: 82,648,405 I9V probably benign Het
Scn7a T C 2: 66,752,260 I98V probably benign Het
Serac1 T A 17: 6,074,253 probably benign Het
Simc1 T C 13: 54,524,660 C274R probably benign Het
Sirt3 A G 7: 140,864,093 probably benign Het
Tctn3 A G 19: 40,597,436 L555P probably damaging Het
Ttc14 A G 3: 33,801,358 I151V probably benign Het
Ush2a T A 1: 188,263,321 Y96* probably null Het
Usp42 T C 5: 143,721,215 T270A possibly damaging Het
Vmn1r31 A G 6: 58,472,799 I27T probably benign Het
Vmn2r93 G A 17: 18,316,644 A530T possibly damaging Het
Other mutations in Gm9631
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02411:Gm9631 APN 11 121943652
IGL02417:Gm9631 APN 11 121943652
IGL02419:Gm9631 APN 11 121943652
IGL02420:Gm9631 APN 11 121943652
R0646:Gm9631 UTSW 11 121945629 missense probably damaging 0.99
R0715:Gm9631 UTSW 11 121942502 missense probably damaging 1.00
R3978:Gm9631 UTSW 11 121943568 missense possibly damaging 0.46
Posted On 2013-10-07