Incidental Mutation 'IGL01326:Gm9631'
ID74248
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm9631
Ensembl Gene
Gene Namepredicted gene 9631
Synonyms
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL01326
Quality Score
Status
Chromosome11
Chromosomal Location121906652-121925337 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 121945628 bp
ZygosityHeterozygous
Amino Acid Change Aspartic acid to Glutamic Acid at position 28 (D28E)
Gene Model predicted gene model for transcript(s):
Predicted Effect possibly damaging
Transcript: ENSMUST00000130783
AA Change: D28E

PolyPhen 2 Score 0.830 (Sensitivity: 0.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000118097
Gene: ENSMUSG00000078564
AA Change: D28E

DomainStartEndE-ValueType
signal peptide 1 20 N/A INTRINSIC
KRAB 30 86 3.16e-12 SMART
ZnF_C2H2 157 177 1.69e2 SMART
ZnF_C2H2 185 207 1.36e-2 SMART
ZnF_C2H2 213 235 6.78e-3 SMART
ZnF_C2H2 241 263 2.79e-4 SMART
ZnF_C2H2 269 291 1.2e-3 SMART
ZnF_C2H2 297 319 9.88e-5 SMART
ZnF_C2H2 325 347 7.78e-3 SMART
ZnF_C2H2 353 375 1.12e-3 SMART
ZnF_C2H2 381 403 7.78e-3 SMART
ZnF_C2H2 409 431 1.5e-4 SMART
ZnF_C2H2 437 459 9.08e-4 SMART
ZnF_C2H2 465 487 1.04e-3 SMART
ZnF_C2H2 493 515 2.27e-4 SMART
ZnF_C2H2 521 543 4.17e-3 SMART
ZnF_C2H2 550 572 1.1e-2 SMART
ZnF_C2H2 578 600 3.95e-4 SMART
ZnF_C2H2 606 628 7.9e-4 SMART
ZnF_C2H2 634 656 9.73e-4 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 47 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adh1 G A 3: 138,286,911 V263M probably damaging Het
Akap13 T A 7: 75,725,348 H1909Q probably benign Het
Atg2b C T 12: 105,622,144 A1936T probably damaging Het
Atp8b3 G T 10: 80,524,376 L954M probably damaging Het
C8a T C 4: 104,856,420 Y171C probably damaging Het
Cd6 A G 19: 10,791,102 S508P probably benign Het
Cdk4 A G 10: 127,064,623 D86G possibly damaging Het
Cdr2l G T 11: 115,390,970 R100S probably benign Het
Cndp1 T A 18: 84,622,232 T283S probably benign Het
Cr2 T C 1: 195,141,221 Y1023C probably null Het
Csmd3 A G 15: 47,849,785 F1494L probably benign Het
Eng G T 2: 32,672,382 G231W probably benign Het
Erp44 A G 4: 48,218,126 V181A probably benign Het
Fam102b A G 3: 108,979,785 V299A possibly damaging Het
Fkbp15 A G 4: 62,323,250 S553P probably damaging Het
Glg1 A G 8: 111,182,573 V495A probably damaging Het
Gnptab G T 10: 88,433,065 L543F probably damaging Het
Hist1h4c A T 13: 23,698,370 I27N probably damaging Het
Khdrbs2 T G 1: 32,657,477 L329R possibly damaging Het
Kidins220 C A 12: 25,038,499 H1080Q probably damaging Het
Maml1 G A 11: 50,265,888 P487S probably benign Het
Marc2 T C 1: 184,833,851 probably benign Het
Me1 C T 9: 86,598,718 probably null Het
Morc2a C T 11: 3,681,775 R569C probably benign Het
Mrc1 A G 2: 14,266,524 Q413R probably damaging Het
Mrgprx1 A T 7: 48,021,769 C77S probably benign Het
Myo1d A T 11: 80,684,321 probably benign Het
Nr4a1 T G 15: 101,274,059 L538R probably damaging Het
Olfm1 T C 2: 28,229,552 Y385H probably damaging Het
Olfr1034 A G 2: 86,047,283 E267G probably damaging Het
Olfr1238 A T 2: 89,406,331 F249L possibly damaging Het
Pkd1 T A 17: 24,576,174 Y2278* probably null Het
Plcg2 T C 8: 117,573,999 probably benign Het
Prkdc G T 16: 15,829,692 C3660F probably benign Het
Ptpn11 T C 5: 121,143,136 D493G probably damaging Het
Rad23b T A 4: 55,383,601 F278I possibly damaging Het
Saxo2 T C 7: 82,648,405 I9V probably benign Het
Scn7a T C 2: 66,752,260 I98V probably benign Het
Serac1 T A 17: 6,074,253 probably benign Het
Simc1 T C 13: 54,524,660 C274R probably benign Het
Sirt3 A G 7: 140,864,093 probably benign Het
Tctn3 A G 19: 40,597,436 L555P probably damaging Het
Ttc14 A G 3: 33,801,358 I151V probably benign Het
Ush2a T A 1: 188,263,321 Y96* probably null Het
Usp42 T C 5: 143,721,215 T270A possibly damaging Het
Vmn1r31 A G 6: 58,472,799 I27T probably benign Het
Vmn2r93 G A 17: 18,316,644 A530T possibly damaging Het
Other mutations in Gm9631
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02411:Gm9631 APN 11 121943652
IGL02417:Gm9631 APN 11 121943652
IGL02419:Gm9631 APN 11 121943652
IGL02420:Gm9631 APN 11 121943652
R0646:Gm9631 UTSW 11 121945629 missense probably damaging 0.99
R0715:Gm9631 UTSW 11 121942502 missense probably damaging 1.00
R3978:Gm9631 UTSW 11 121943568 missense possibly damaging 0.46
Posted On2013-10-07