Incidental Mutation 'R1274:Vmn1r234'
| ID |
150850 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Vmn1r234
|
| Ensembl Gene |
ENSMUSG00000057203 |
| Gene Name |
vomeronasal 1 receptor 234 |
| Synonyms |
V1rf1 |
| MMRRC Submission |
039340-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.058)
|
| Stock # |
R1274 (G1)
|
| Quality Score |
217 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
21449088-21450078 bp(+) (GRCm39) |
| Type of Mutation |
frame shift |
| DNA Base Change (assembly) |
CTT to CTTT
at 21449513 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000078579
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000079633]
|
| AlphaFold |
Q8R298 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000079633
|
| SMART Domains |
Protein: ENSMUSP00000078579
Gene: ENSMUSG00000057203
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
25 |
315 |
2.8e-14 |
PFAM |
|
Pfam:V1R
|
57 |
318 |
2.3e-26 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000177028
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.1%
- 20x: 95.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 17 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Afap1l2 |
T |
C |
19: 56,902,995 (GRCm39) |
D728G |
probably benign |
Het |
| Anpep |
C |
T |
7: 79,488,004 (GRCm39) |
E518K |
probably benign |
Het |
| Ceacam3 |
A |
G |
7: 16,897,064 (GRCm39) |
R677G |
probably damaging |
Het |
| Col16a1 |
T |
A |
4: 129,991,594 (GRCm39) |
M1431K |
probably damaging |
Het |
| Dync1h1 |
G |
A |
12: 110,602,943 (GRCm39) |
E2195K |
probably benign |
Het |
| Gm6563 |
A |
T |
19: 23,653,701 (GRCm39) |
I164F |
probably benign |
Het |
| Msantd5f6 |
T |
C |
4: 73,321,313 (GRCm39) |
Y148C |
probably damaging |
Het |
| Nav2 |
C |
A |
7: 49,254,178 (GRCm39) |
Y2325* |
probably null |
Het |
| Or10ak12 |
T |
C |
4: 118,666,593 (GRCm39) |
N156S |
probably benign |
Het |
| Or5d36 |
A |
C |
2: 87,900,939 (GRCm39) |
C262W |
probably damaging |
Het |
| P2ry12 |
T |
C |
3: 59,124,641 (GRCm39) |
T345A |
possibly damaging |
Het |
| Ptpn13 |
C |
T |
5: 103,698,126 (GRCm39) |
P1078S |
probably damaging |
Het |
| Rgs20 |
G |
A |
1: 4,982,670 (GRCm39) |
T166I |
probably damaging |
Het |
| Sik1 |
A |
T |
17: 32,065,549 (GRCm39) |
L683Q |
possibly damaging |
Het |
| Slc7a5 |
C |
T |
8: 122,610,453 (GRCm39) |
V454M |
probably benign |
Het |
| Snx30 |
A |
G |
4: 59,885,133 (GRCm39) |
T258A |
probably benign |
Het |
| Zfp335 |
GTCCTCCTCCTCCTCCTC |
GTCCTCCTCCTCCTC |
2: 164,749,388 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Vmn1r234 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00089:Vmn1r234
|
APN |
17 |
21,449,860 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01485:Vmn1r234
|
APN |
17 |
21,449,171 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
IGL02149:Vmn1r234
|
APN |
17 |
21,449,269 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02291:Vmn1r234
|
APN |
17 |
21,449,193 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL02993:Vmn1r234
|
APN |
17 |
21,449,965 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03223:Vmn1r234
|
APN |
17 |
21,449,653 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0626:Vmn1r234
|
UTSW |
17 |
21,450,007 (GRCm39) |
missense |
probably benign |
0.17 |
|
R1275:Vmn1r234
|
UTSW |
17 |
21,449,513 (GRCm39) |
frame shift |
probably null |
|
|
R1288:Vmn1r234
|
UTSW |
17 |
21,449,513 (GRCm39) |
frame shift |
probably null |
|
|
R1289:Vmn1r234
|
UTSW |
17 |
21,449,513 (GRCm39) |
frame shift |
probably null |
|
|
R1319:Vmn1r234
|
UTSW |
17 |
21,449,172 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1412:Vmn1r234
|
UTSW |
17 |
21,449,512 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2323:Vmn1r234
|
UTSW |
17 |
21,449,965 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3755:Vmn1r234
|
UTSW |
17 |
21,449,271 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4299:Vmn1r234
|
UTSW |
17 |
21,449,283 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5301:Vmn1r234
|
UTSW |
17 |
21,449,589 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5741:Vmn1r234
|
UTSW |
17 |
21,449,731 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6197:Vmn1r234
|
UTSW |
17 |
21,449,589 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6218:Vmn1r234
|
UTSW |
17 |
21,449,983 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6486:Vmn1r234
|
UTSW |
17 |
21,449,604 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7482:Vmn1r234
|
UTSW |
17 |
21,449,637 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7635:Vmn1r234
|
UTSW |
17 |
21,449,479 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8295:Vmn1r234
|
UTSW |
17 |
21,449,101 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9506:Vmn1r234
|
UTSW |
17 |
21,449,503 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9530:Vmn1r234
|
UTSW |
17 |
21,449,104 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0028:Vmn1r234
|
UTSW |
17 |
21,449,152 (GRCm39) |
missense |
probably benign |
0.17 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTGTTCCACAAGCAATGGCAGC -3'
(R):5'- CTGTGCCTGTGCAAAATGAGAACC -3'
Sequencing Primer
(F):5'- CACAAGCAATGGCAGCTTTTG -3'
(R):5'- ACATTGCACAATTTTGCAGACA -3'
|
| Posted On |
2014-01-29 |
Incidental Mutation