Incidental Mutation 'IGL00089:Patj'
| ID |
1723 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Patj
|
| Ensembl Gene |
ENSMUSG00000061859 |
| Gene Name |
PATJ, crumbs cell polarity complex component |
| Synonyms |
Cipp, Inadl |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
IGL00089
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
4 |
| Chromosomal Location |
98284022-98607840 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 98353343 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Leucine
at position 629
(F629L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000102649
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041284]
[ENSMUST00000107029]
[ENSMUST00000107033]
[ENSMUST00000107034]
|
| AlphaFold |
Q63ZW7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000041284
AA Change: F633L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000049176
Gene: ENSMUSG00000061859
AA Change: F633L
| Domain | Start | End | E-Value | Type |
|---|
|
L27
|
8 |
68 |
6.53e-9 |
SMART |
|
PDZ
|
143 |
221 |
1.78e-20 |
SMART |
|
PDZ
|
256 |
328 |
1.15e-23 |
SMART |
|
PDZ
|
374 |
453 |
3.15e-21 |
SMART |
|
coiled coil region
|
486 |
513 |
N/A |
INTRINSIC |
|
PDZ
|
570 |
641 |
1.28e-12 |
SMART |
|
PDZ
|
696 |
775 |
9.5e-16 |
SMART |
|
low complexity region
|
980 |
991 |
N/A |
INTRINSIC |
|
low complexity region
|
1054 |
1062 |
N/A |
INTRINSIC |
|
PDZ
|
1083 |
1166 |
8.65e-19 |
SMART |
|
PDZ
|
1253 |
1328 |
6.12e-19 |
SMART |
|
low complexity region
|
1356 |
1366 |
N/A |
INTRINSIC |
|
low complexity region
|
1410 |
1428 |
N/A |
INTRINSIC |
|
PDZ
|
1480 |
1555 |
4.36e-24 |
SMART |
|
PDZ
|
1577 |
1650 |
2.49e-19 |
SMART |
|
PDZ
|
1718 |
1795 |
2.13e-18 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000107029
AA Change: F60L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000102644
Gene: ENSMUSG00000061859
AA Change: F60L
| Domain | Start | End | E-Value | Type |
|---|
|
PDZ
|
1 |
68 |
1e-9 |
SMART |
|
PDZ
|
123 |
202 |
4.7e-18 |
SMART |
|
low complexity region
|
407 |
418 |
N/A |
INTRINSIC |
|
low complexity region
|
481 |
489 |
N/A |
INTRINSIC |
|
PDZ
|
510 |
593 |
4.3e-21 |
SMART |
|
PDZ
|
680 |
755 |
2.9e-21 |
SMART |
|
low complexity region
|
783 |
793 |
N/A |
INTRINSIC |
|
low complexity region
|
837 |
855 |
N/A |
INTRINSIC |
|
PDZ
|
907 |
982 |
2.2e-26 |
SMART |
|
PDZ
|
1004 |
1077 |
1.2e-21 |
SMART |
|
PDZ
|
1145 |
1222 |
1e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000107033
|
| SMART Domains |
Protein: ENSMUSP00000102648
Gene: ENSMUSG00000061859
| Domain | Start | End | E-Value | Type |
|---|
|
L27
|
8 |
68 |
6.53e-9 |
SMART |
|
PDZ
|
143 |
221 |
1.78e-20 |
SMART |
|
PDZ
|
256 |
328 |
1.15e-23 |
SMART |
|
PDZ
|
374 |
453 |
3.15e-21 |
SMART |
|
coiled coil region
|
486 |
513 |
N/A |
INTRINSIC |
|
low complexity region
|
648 |
659 |
N/A |
INTRINSIC |
|
low complexity region
|
722 |
730 |
N/A |
INTRINSIC |
|
PDZ
|
751 |
834 |
8.65e-19 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000107034
AA Change: F629L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000102649
Gene: ENSMUSG00000061859
AA Change: F629L
| Domain | Start | End | E-Value | Type |
|---|
|
L27
|
8 |
68 |
6.53e-9 |
SMART |
|
PDZ
|
143 |
221 |
1.78e-20 |
SMART |
|
PDZ
|
256 |
328 |
1.15e-23 |
SMART |
|
PDZ
|
374 |
453 |
3.15e-21 |
SMART |
|
coiled coil region
|
486 |
513 |
N/A |
INTRINSIC |
|
PDZ
|
566 |
637 |
1.28e-12 |
SMART |
|
PDZ
|
692 |
771 |
9.5e-16 |
SMART |
|
low complexity region
|
976 |
987 |
N/A |
INTRINSIC |
|
low complexity region
|
1050 |
1058 |
N/A |
INTRINSIC |
|
PDZ
|
1079 |
1162 |
8.65e-19 |
SMART |
|
PDZ
|
1249 |
1324 |
6.12e-19 |
SMART |
|
low complexity region
|
1352 |
1362 |
N/A |
INTRINSIC |
|
low complexity region
|
1382 |
1400 |
N/A |
INTRINSIC |
|
PDZ
|
1452 |
1499 |
7.78e0 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000142103
AA Change: F111L
|
| SMART Domains |
Protein: ENSMUSP00000116021
Gene: ENSMUSG00000061859
AA Change: F111L
| Domain | Start | End | E-Value | Type |
|---|
|
PDZ
|
49 |
120 |
1.28e-12 |
SMART |
|
PDZ
|
175 |
254 |
9.5e-16 |
SMART |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a multivalent PDZ domain protein, which is expressed exclusively in brain and kidney. This protein selectively interacts with inward rectifier K+ (Kir) family members, N-methyl-D-aspartate receptor subunits, neurexins and neuroligins, as well as cell surface molecules enriched in synaptic membranes. Thus, this protein may serve as a scaffold that brings structurally diverse but functionally connected proteins into close proximity at the synapse. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
All alleles(5) : Gene trapped(5) |
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A430033K04Rik |
T |
C |
5: 138,645,854 (GRCm39) |
S580P |
probably damaging |
Het |
| Abca12 |
T |
A |
1: 71,342,700 (GRCm39) |
I927F |
possibly damaging |
Het |
| Abca8a |
A |
G |
11: 109,941,765 (GRCm39) |
V1168A |
possibly damaging |
Het |
| Abcc1 |
T |
A |
16: 14,278,847 (GRCm39) |
N1052K |
probably benign |
Het |
| Adamts13 |
C |
A |
2: 26,895,373 (GRCm39) |
Q1155K |
probably benign |
Het |
| Adgre4 |
A |
T |
17: 56,098,915 (GRCm39) |
|
probably benign |
Het |
| Ahsa2 |
T |
C |
11: 23,446,837 (GRCm39) |
E42G |
probably damaging |
Het |
| Ankk1 |
T |
G |
9: 49,333,200 (GRCm39) |
I95L |
probably benign |
Het |
| Anpep |
A |
T |
7: 79,491,734 (GRCm39) |
L89Q |
probably damaging |
Het |
| Arl5a |
T |
C |
2: 52,306,083 (GRCm39) |
N83S |
probably benign |
Het |
| Atp11b |
A |
G |
3: 35,863,525 (GRCm39) |
|
probably null |
Het |
| Atp6v0a2 |
T |
C |
5: 124,798,841 (GRCm39) |
F849L |
probably benign |
Het |
| BC106179 |
A |
G |
16: 23,043,022 (GRCm39) |
|
probably benign |
Het |
| Bcl2a1c |
T |
C |
9: 114,159,608 (GRCm39) |
*129Q |
probably null |
Het |
| C2cd5 |
T |
C |
6: 142,963,671 (GRCm39) |
I888V |
probably null |
Het |
| Calb2 |
A |
T |
8: 110,872,303 (GRCm39) |
L227Q |
probably damaging |
Het |
| Ccp110 |
G |
T |
7: 118,321,647 (GRCm39) |
C434F |
possibly damaging |
Het |
| Cd209c |
A |
T |
8: 3,990,339 (GRCm39) |
C160S |
probably damaging |
Het |
| Chmp1a |
A |
G |
8: 123,935,758 (GRCm39) |
|
probably null |
Het |
| Col6a6 |
T |
A |
9: 105,635,390 (GRCm39) |
|
probably null |
Het |
| Cyld |
T |
A |
8: 89,432,085 (GRCm39) |
C28S |
probably benign |
Het |
| Dapk1 |
A |
T |
13: 60,908,854 (GRCm39) |
I1156F |
probably benign |
Het |
| Dennd1a |
A |
T |
2: 38,133,454 (GRCm39) |
Y16* |
probably null |
Het |
| Dennd3 |
T |
G |
15: 73,438,982 (GRCm39) |
S1117A |
probably benign |
Het |
| Dgka |
A |
T |
10: 128,568,955 (GRCm39) |
D203E |
probably damaging |
Het |
| Dhx15 |
G |
T |
5: 52,324,117 (GRCm39) |
L392I |
probably damaging |
Het |
| Dnah10 |
A |
G |
5: 124,823,680 (GRCm39) |
D567G |
probably benign |
Het |
| Eaf1 |
T |
A |
14: 31,226,483 (GRCm39) |
|
probably null |
Het |
| Efnb2 |
T |
C |
8: 8,710,589 (GRCm39) |
D9G |
probably benign |
Het |
| Fcrla |
A |
T |
1: 170,755,067 (GRCm39) |
C15S |
probably benign |
Het |
| Flt3 |
T |
C |
5: 147,291,686 (GRCm39) |
N588S |
probably damaging |
Het |
| Garre1 |
A |
T |
7: 33,945,412 (GRCm39) |
|
probably benign |
Het |
| Gm10146 |
A |
T |
10: 78,229,307 (GRCm39) |
|
noncoding transcript |
Het |
| Gnpat |
T |
C |
8: 125,603,653 (GRCm39) |
|
probably benign |
Het |
| Golm2 |
T |
C |
2: 121,741,274 (GRCm39) |
|
probably benign |
Het |
| Gpr39 |
A |
C |
1: 125,800,468 (GRCm39) |
R406S |
probably benign |
Het |
| H2-Aa |
T |
C |
17: 34,503,504 (GRCm39) |
H31R |
probably damaging |
Het |
| Helz2 |
G |
T |
2: 180,871,495 (GRCm39) |
R2706S |
probably damaging |
Het |
| Hip1r |
T |
A |
5: 124,127,798 (GRCm39) |
|
probably null |
Het |
| Hnf4g |
A |
G |
3: 3,713,142 (GRCm39) |
T239A |
probably benign |
Het |
| Hps5 |
A |
T |
7: 46,425,362 (GRCm39) |
I413N |
probably damaging |
Het |
| Hspg2 |
G |
A |
4: 137,256,131 (GRCm39) |
G1413R |
probably damaging |
Het |
| Itgax |
T |
G |
7: 127,734,498 (GRCm39) |
M352R |
probably damaging |
Het |
| Katna1 |
T |
A |
10: 7,638,568 (GRCm39) |
M433K |
probably damaging |
Het |
| Kcna4 |
T |
G |
2: 107,126,207 (GRCm39) |
S314A |
probably damaging |
Het |
| Kif13b |
C |
T |
14: 64,907,142 (GRCm39) |
T42I |
possibly damaging |
Het |
| Krt78 |
G |
A |
15: 101,855,945 (GRCm39) |
T622I |
probably benign |
Het |
| Krt86 |
T |
A |
15: 101,374,396 (GRCm39) |
M263K |
possibly damaging |
Het |
| Lap3 |
A |
G |
5: 45,663,511 (GRCm39) |
|
probably benign |
Het |
| Lepr |
A |
T |
4: 101,672,232 (GRCm39) |
R1085S |
probably benign |
Het |
| Lmcd1 |
A |
G |
6: 112,306,769 (GRCm39) |
I314V |
probably benign |
Het |
| Luc7l2 |
T |
C |
6: 38,585,105 (GRCm39) |
|
probably benign |
Het |
| Mcm2 |
T |
A |
6: 88,870,383 (GRCm39) |
M117L |
probably benign |
Het |
| Mdh2 |
T |
C |
5: 135,815,138 (GRCm39) |
Y133H |
probably damaging |
Het |
| Minar1 |
C |
T |
9: 89,483,853 (GRCm39) |
V515I |
probably benign |
Het |
| Mlkl |
T |
A |
8: 112,046,060 (GRCm39) |
R317* |
probably null |
Het |
| Mrps34 |
T |
C |
17: 25,114,344 (GRCm39) |
L68P |
probably damaging |
Het |
| Muc4 |
G |
A |
16: 32,754,086 (GRCm38) |
G1321R |
probably benign |
Het |
| Myo18a |
A |
G |
11: 77,738,764 (GRCm39) |
E1299G |
probably damaging |
Het |
| Nlrp14 |
T |
C |
7: 106,791,709 (GRCm39) |
L139P |
possibly damaging |
Het |
| Nudcd2 |
A |
G |
11: 40,627,413 (GRCm39) |
D86G |
probably damaging |
Het |
| Or10u4 |
T |
A |
10: 129,801,673 (GRCm39) |
R293W |
probably damaging |
Het |
| Or4c107 |
T |
A |
2: 88,789,110 (GRCm39) |
I100N |
probably damaging |
Het |
| Or4f62 |
A |
T |
2: 111,986,412 (GRCm39) |
M39L |
probably benign |
Het |
| Rad23a |
A |
G |
8: 85,562,524 (GRCm39) |
F280L |
probably damaging |
Het |
| Ralgapa1 |
C |
A |
12: 55,769,558 (GRCm39) |
G811V |
probably damaging |
Het |
| St18 |
A |
G |
1: 6,872,796 (GRCm39) |
D177G |
probably benign |
Het |
| Sult1c2 |
A |
C |
17: 54,140,147 (GRCm39) |
Y159* |
probably null |
Het |
| Surf6 |
T |
A |
2: 26,783,081 (GRCm39) |
|
probably null |
Het |
| Susd6 |
T |
G |
12: 80,916,841 (GRCm39) |
|
probably benign |
Het |
| Sypl2 |
G |
A |
3: 108,133,742 (GRCm39) |
|
probably benign |
Het |
| Ubr5 |
A |
T |
15: 37,984,280 (GRCm39) |
F2289Y |
probably damaging |
Het |
| Vcl |
T |
C |
14: 21,037,071 (GRCm39) |
I223T |
probably benign |
Het |
| Vmn1r234 |
C |
T |
17: 21,449,860 (GRCm39) |
T258I |
possibly damaging |
Het |
| Vmn2r58 |
T |
A |
7: 41,513,854 (GRCm39) |
K263M |
possibly damaging |
Het |
| Vmo1 |
A |
T |
11: 70,404,424 (GRCm39) |
N192K |
probably damaging |
Het |
| Wrnip1 |
A |
G |
13: 33,000,312 (GRCm39) |
N440D |
probably damaging |
Het |
| Zc3h4 |
T |
C |
7: 16,156,159 (GRCm39) |
Y264H |
unknown |
Het |
| Zfp639 |
T |
G |
3: 32,573,902 (GRCm39) |
|
probably null |
Het |
| Zfp831 |
T |
C |
2: 174,488,078 (GRCm39) |
Y918H |
possibly damaging |
Het |
|
| Other mutations in Patj |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00095:Patj
|
APN |
4 |
98,423,799 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL00517:Patj
|
APN |
4 |
98,329,308 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL00802:Patj
|
APN |
4 |
98,312,643 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL01064:Patj
|
APN |
4 |
98,385,210 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01110:Patj
|
APN |
4 |
98,301,261 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01407:Patj
|
APN |
4 |
98,301,287 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
IGL01821:Patj
|
APN |
4 |
98,344,448 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02399:Patj
|
APN |
4 |
98,480,173 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02494:Patj
|
APN |
4 |
98,592,224 (GRCm39) |
splice site |
probably benign |
|
|
IGL02803:Patj
|
APN |
4 |
98,314,301 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02931:Patj
|
APN |
4 |
98,299,410 (GRCm39) |
splice site |
probably benign |
|
|
IGL03017:Patj
|
APN |
4 |
98,353,264 (GRCm39) |
splice site |
probably benign |
|
|
IGL03115:Patj
|
APN |
4 |
98,332,040 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03209:Patj
|
APN |
4 |
98,353,377 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL03377:Patj
|
APN |
4 |
98,353,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
D4186:Patj
|
UTSW |
4 |
98,526,999 (GRCm39) |
missense |
probably benign |
0.17 |
|
PIT4531001:Patj
|
UTSW |
4 |
98,329,327 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0136:Patj
|
UTSW |
4 |
98,555,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0294:Patj
|
UTSW |
4 |
98,385,285 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0376:Patj
|
UTSW |
4 |
98,457,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0463:Patj
|
UTSW |
4 |
98,562,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0465:Patj
|
UTSW |
4 |
98,423,744 (GRCm39) |
splice site |
probably null |
|
|
R0466:Patj
|
UTSW |
4 |
98,576,393 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0544:Patj
|
UTSW |
4 |
98,457,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0624:Patj
|
UTSW |
4 |
98,569,472 (GRCm39) |
splice site |
probably benign |
|
|
R0657:Patj
|
UTSW |
4 |
98,555,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1281:Patj
|
UTSW |
4 |
98,304,932 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1393:Patj
|
UTSW |
4 |
98,312,648 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1480:Patj
|
UTSW |
4 |
98,357,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1667:Patj
|
UTSW |
4 |
98,301,264 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1728:Patj
|
UTSW |
4 |
98,320,017 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1729:Patj
|
UTSW |
4 |
98,320,017 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1797:Patj
|
UTSW |
4 |
98,575,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1818:Patj
|
UTSW |
4 |
98,511,885 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1835:Patj
|
UTSW |
4 |
98,379,827 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1880:Patj
|
UTSW |
4 |
98,385,477 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2009:Patj
|
UTSW |
4 |
98,344,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2090:Patj
|
UTSW |
4 |
98,325,560 (GRCm39) |
unclassified |
probably benign |
|
|
R2120:Patj
|
UTSW |
4 |
98,344,462 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2180:Patj
|
UTSW |
4 |
98,411,739 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2655:Patj
|
UTSW |
4 |
98,325,687 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R3156:Patj
|
UTSW |
4 |
98,562,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3749:Patj
|
UTSW |
4 |
98,357,837 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3767:Patj
|
UTSW |
4 |
98,569,456 (GRCm39) |
nonsense |
probably null |
|
|
R3913:Patj
|
UTSW |
4 |
98,457,338 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3917:Patj
|
UTSW |
4 |
98,480,245 (GRCm39) |
nonsense |
probably null |
|
|
R3918:Patj
|
UTSW |
4 |
98,344,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4299:Patj
|
UTSW |
4 |
98,565,558 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4355:Patj
|
UTSW |
4 |
98,538,691 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4471:Patj
|
UTSW |
4 |
98,423,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4762:Patj
|
UTSW |
4 |
98,293,807 (GRCm39) |
nonsense |
probably null |
|
|
R4877:Patj
|
UTSW |
4 |
98,457,295 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4945:Patj
|
UTSW |
4 |
98,383,301 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5274:Patj
|
UTSW |
4 |
98,407,218 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5343:Patj
|
UTSW |
4 |
98,564,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5554:Patj
|
UTSW |
4 |
98,342,633 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5688:Patj
|
UTSW |
4 |
98,409,047 (GRCm39) |
nonsense |
probably null |
|
|
R5880:Patj
|
UTSW |
4 |
98,299,382 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5972:Patj
|
UTSW |
4 |
98,457,290 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6149:Patj
|
UTSW |
4 |
98,312,562 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R6192:Patj
|
UTSW |
4 |
98,344,394 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6265:Patj
|
UTSW |
4 |
98,357,804 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6350:Patj
|
UTSW |
4 |
98,293,855 (GRCm39) |
missense |
probably benign |
0.26 |
|
R6363:Patj
|
UTSW |
4 |
98,320,097 (GRCm39) |
missense |
probably benign |
0.25 |
|
R6434:Patj
|
UTSW |
4 |
98,379,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6496:Patj
|
UTSW |
4 |
98,304,989 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6896:Patj
|
UTSW |
4 |
98,314,287 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7039:Patj
|
UTSW |
4 |
98,457,315 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7040:Patj
|
UTSW |
4 |
98,329,317 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7052:Patj
|
UTSW |
4 |
98,565,497 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7066:Patj
|
UTSW |
4 |
98,301,434 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7236:Patj
|
UTSW |
4 |
98,299,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7242:Patj
|
UTSW |
4 |
98,480,170 (GRCm39) |
missense |
probably benign |
0.26 |
|
R7260:Patj
|
UTSW |
4 |
98,304,970 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7412:Patj
|
UTSW |
4 |
98,299,376 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7493:Patj
|
UTSW |
4 |
98,383,298 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7570:Patj
|
UTSW |
4 |
98,312,737 (GRCm39) |
splice site |
probably null |
|
|
R7571:Patj
|
UTSW |
4 |
98,457,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7626:Patj
|
UTSW |
4 |
98,435,224 (GRCm39) |
missense |
probably benign |
0.35 |
|
R7658:Patj
|
UTSW |
4 |
98,576,416 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7664:Patj
|
UTSW |
4 |
98,385,187 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7669:Patj
|
UTSW |
4 |
98,407,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7796:Patj
|
UTSW |
4 |
98,435,220 (GRCm39) |
start codon destroyed |
probably benign |
0.05 |
|
R7870:Patj
|
UTSW |
4 |
98,312,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7883:Patj
|
UTSW |
4 |
98,499,372 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7948:Patj
|
UTSW |
4 |
98,312,547 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8050:Patj
|
UTSW |
4 |
98,427,201 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8183:Patj
|
UTSW |
4 |
98,562,466 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8239:Patj
|
UTSW |
4 |
98,570,308 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8483:Patj
|
UTSW |
4 |
98,312,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8546:Patj
|
UTSW |
4 |
98,325,634 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8746:Patj
|
UTSW |
4 |
98,394,067 (GRCm39) |
intron |
probably benign |
|
|
R8844:Patj
|
UTSW |
4 |
98,480,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8905:Patj
|
UTSW |
4 |
98,385,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8912:Patj
|
UTSW |
4 |
98,385,565 (GRCm39) |
missense |
|
|
|
R8959:Patj
|
UTSW |
4 |
98,480,212 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9083:Patj
|
UTSW |
4 |
98,401,871 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9173:Patj
|
UTSW |
4 |
98,526,958 (GRCm39) |
missense |
probably benign |
|
|
R9206:Patj
|
UTSW |
4 |
98,427,310 (GRCm39) |
missense |
unknown |
|
|
R9208:Patj
|
UTSW |
4 |
98,427,310 (GRCm39) |
missense |
unknown |
|
|
R9347:Patj
|
UTSW |
4 |
98,576,484 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9560:Patj
|
UTSW |
4 |
98,570,289 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9609:Patj
|
UTSW |
4 |
98,576,473 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9617:Patj
|
UTSW |
4 |
98,393,991 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9658:Patj
|
UTSW |
4 |
98,353,377 (GRCm39) |
missense |
probably null |
1.00 |
|
R9756:Patj
|
UTSW |
4 |
98,565,535 (GRCm39) |
missense |
probably benign |
|
|
Z1176:Patj
|
UTSW |
4 |
98,564,555 (GRCm39) |
nonsense |
probably null |
|
|
Z1176:Patj
|
UTSW |
4 |
98,499,367 (GRCm39) |
missense |
probably benign |
0.11 |
|
Z1177:Patj
|
UTSW |
4 |
98,385,411 (GRCm39) |
missense |
probably benign |
0.01 |
|
| Posted On |
2011-07-12 |
Incidental Mutation