Incidental Mutation 'IGL01915:Rsad1'
| ID |
179921 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Rsad1
|
| Ensembl Gene |
ENSMUSG00000039096 |
| Gene Name |
radical S-adenosyl methionine domain containing 1 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.128)
|
| Stock # |
IGL01915
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
11 |
| Chromosomal Location |
94430624-94440081 bp(-) (GRCm39) |
| Type of Mutation |
splice site (6 bp from exon) |
| DNA Base Change (assembly) |
A to G
at 94439803 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037361
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040487]
|
| AlphaFold |
Q5SUV1 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000040487
|
| SMART Domains |
Protein: ENSMUSP00000037361
Gene: ENSMUSG00000039096
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
24 |
N/A |
INTRINSIC |
|
Elp3
|
39 |
259 |
6.54e-40 |
SMART |
|
Pfam:HemN_C
|
346 |
414 |
7.7e-13 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000132274
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000143299
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000148888
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 32 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abt1 |
T |
C |
13: 23,607,938 (GRCm39) |
E22G |
unknown |
Het |
| Aoc1l2 |
T |
A |
6: 48,908,582 (GRCm39) |
D527E |
probably damaging |
Het |
| Atp11b |
T |
G |
3: 35,885,612 (GRCm39) |
H668Q |
probably damaging |
Het |
| Birc6 |
T |
A |
17: 74,938,715 (GRCm39) |
V2687D |
probably benign |
Het |
| Cadm3 |
T |
C |
1: 173,168,675 (GRCm39) |
T298A |
possibly damaging |
Het |
| Car12 |
G |
A |
9: 66,670,552 (GRCm39) |
A174T |
possibly damaging |
Het |
| Ccdc180 |
T |
C |
4: 45,904,544 (GRCm39) |
L380P |
probably damaging |
Het |
| Col7a1 |
A |
T |
9: 108,784,813 (GRCm39) |
R214W |
unknown |
Het |
| Cyp2d26 |
T |
G |
15: 82,674,450 (GRCm39) |
R477S |
probably benign |
Het |
| Dgkd |
T |
C |
1: 87,853,780 (GRCm39) |
V541A |
possibly damaging |
Het |
| Dip2b |
T |
A |
15: 100,076,392 (GRCm39) |
F797I |
probably damaging |
Het |
| Dot1l |
A |
T |
10: 80,616,728 (GRCm39) |
N63I |
probably damaging |
Het |
| Gm21738 |
G |
A |
14: 19,416,979 (GRCm38) |
S144L |
probably benign |
Het |
| Ints5 |
T |
C |
19: 8,874,357 (GRCm39) |
I772T |
probably benign |
Het |
| Nosip |
T |
A |
7: 44,726,283 (GRCm39) |
I230N |
probably damaging |
Het |
| Or2r3 |
A |
T |
6: 42,448,223 (GRCm39) |
D296E |
probably benign |
Het |
| Or4d11 |
A |
T |
19: 12,013,461 (GRCm39) |
L215Q |
probably damaging |
Het |
| Or5ac22 |
T |
A |
16: 59,135,473 (GRCm39) |
Q99L |
probably damaging |
Het |
| Or6c210 |
G |
A |
10: 129,496,519 (GRCm39) |
M281I |
probably benign |
Het |
| Orc5 |
A |
T |
5: 22,727,381 (GRCm39) |
|
probably benign |
Het |
| Parp1 |
A |
G |
1: 180,425,907 (GRCm39) |
I879M |
probably damaging |
Het |
| Pcdh18 |
A |
G |
3: 49,699,370 (GRCm39) |
S1031P |
probably benign |
Het |
| Pdzd2 |
A |
G |
15: 12,371,725 (GRCm39) |
S2557P |
probably damaging |
Het |
| Rccd1 |
T |
C |
7: 79,969,966 (GRCm39) |
|
probably benign |
Het |
| Samd9l |
A |
T |
6: 3,373,864 (GRCm39) |
C1132* |
probably null |
Het |
| Sema6d |
A |
G |
2: 124,500,491 (GRCm39) |
|
probably benign |
Het |
| Slc10a5 |
T |
C |
3: 10,400,580 (GRCm39) |
N27D |
probably damaging |
Het |
| Slco1a5 |
C |
T |
6: 142,189,599 (GRCm39) |
M462I |
probably benign |
Het |
| Tyw5 |
T |
C |
1: 57,440,628 (GRCm39) |
T45A |
probably damaging |
Het |
| Usp21 |
T |
A |
1: 171,110,307 (GRCm39) |
Q489L |
possibly damaging |
Het |
| Vmn2r129 |
C |
T |
4: 156,690,549 (GRCm39) |
|
noncoding transcript |
Het |
| Vmn2r20 |
A |
G |
6: 123,370,924 (GRCm39) |
S519P |
possibly damaging |
Het |
|
| Other mutations in Rsad1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01104:Rsad1
|
APN |
11 |
94,434,466 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R0271:Rsad1
|
UTSW |
11 |
94,439,290 (GRCm39) |
splice site |
probably benign |
|
|
R0619:Rsad1
|
UTSW |
11 |
94,433,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1147:Rsad1
|
UTSW |
11 |
94,434,966 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1147:Rsad1
|
UTSW |
11 |
94,434,966 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2069:Rsad1
|
UTSW |
11 |
94,439,951 (GRCm39) |
start gained |
probably benign |
|
|
R3831:Rsad1
|
UTSW |
11 |
94,434,130 (GRCm39) |
missense |
probably benign |
0.45 |
|
R3833:Rsad1
|
UTSW |
11 |
94,434,130 (GRCm39) |
missense |
probably benign |
0.45 |
|
R4152:Rsad1
|
UTSW |
11 |
94,439,449 (GRCm39) |
intron |
probably benign |
|
|
R4467:Rsad1
|
UTSW |
11 |
94,435,356 (GRCm39) |
missense |
probably benign |
|
|
R4672:Rsad1
|
UTSW |
11 |
94,434,444 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5452:Rsad1
|
UTSW |
11 |
94,434,515 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6190:Rsad1
|
UTSW |
11 |
94,439,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6608:Rsad1
|
UTSW |
11 |
94,433,435 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6749:Rsad1
|
UTSW |
11 |
94,434,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7821:Rsad1
|
UTSW |
11 |
94,435,288 (GRCm39) |
missense |
probably benign |
|
|
R8818:Rsad1
|
UTSW |
11 |
94,439,100 (GRCm39) |
missense |
probably benign |
0.20 |
|
R8984:Rsad1
|
UTSW |
11 |
94,439,010 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9714:Rsad1
|
UTSW |
11 |
94,435,298 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0024:Rsad1
|
UTSW |
11 |
94,439,807 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1177:Rsad1
|
UTSW |
11 |
94,433,811 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
| Posted On |
2014-05-07 |
Incidental Mutation