Mutagenetix > Incidental Mutation

Incidental Mutation 'R3910:Gm7104'

309349

Institutional Source

Beutler Lab

Gene Symbol

Gm7104

Ensembl Gene

ENSMUSG00000094635

Gene Name

predicted gene 7104

Synonyms

MMRRC Submission

040815-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.398) question?

Stock #

R3910 (G1)

Quality Score

172

Status

Validated

Chromosome

Chromosomal Location

88251308-88253839 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

C to T at 88251364 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000179741

SMART Domains

Protein: ENSMUSP00000136935
Gene: ENSMUSG00000094635

Domain	Start	End	E-Value	Type
Pfam:EloA-BP1	80	248	1.6e-64	PFAM
EXOIII	345	504	5.07e-38	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000223359

Meta Mutation Damage Score

0.4666

Coding Region Coverage

1x: 99.2%
3x: 98.7%
10x: 97.4%
20x: 95.5%

Validation Efficiency

97% (36/37)

Allele List at MGI

Other mutations in this stock

Total: 30 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Bod1l	T	C	5: 41,974,441 (GRCm39)	E2291G	probably damaging	Het
Cchcr1	T	C	17: 35,836,233 (GRCm39)	V341A	probably damaging	Het
Cimip3	AC	A	17: 47,744,348 (GRCm39)		probably benign	Het
Dsg1c	T	C	18: 20,399,253 (GRCm39)	V119A	possibly damaging	Het
Fap	A	G	2: 62,386,448 (GRCm39)	S58P	probably damaging	Het
Flnc	A	T	6: 29,459,426 (GRCm39)	T2509S	probably damaging	Het
Fnip2	A	T	3: 79,386,812 (GRCm39)	D971E	possibly damaging	Het
Gab2	A	G	7: 96,948,280 (GRCm39)	Y290C	probably damaging	Het
Ints10	T	A	8: 69,266,272 (GRCm39)	S478T	probably damaging	Het
Iqca1l	A	T	5: 24,750,440 (GRCm39)		probably benign	Het
Kirrel1	C	T	3: 86,996,458 (GRCm39)	M380I	probably null	Het
Krt90	G	A	15: 101,471,218 (GRCm39)	R15W	probably damaging	Het
Lgr5	A	G	10: 115,423,368 (GRCm39)	S11P	possibly damaging	Het
Mycn	T	A	12: 12,987,281 (GRCm39)	N372I	probably damaging	Het
Or2ag18	A	T	7: 106,405,072 (GRCm39)	V199D	probably damaging	Het
Or9a2	A	G	6: 41,749,083 (GRCm39)	V50A	probably benign	Het
Paxbp1	T	A	16: 90,839,569 (GRCm39)	E117V	probably damaging	Het
Phc2	T	C	4: 128,637,351 (GRCm39)		probably null	Het
Prr5	T	A	15: 84,587,345 (GRCm39)	V365E	probably benign	Het
Rev3l	A	G	10: 39,696,552 (GRCm39)	I521M	probably damaging	Het
Robo3	A	T	9: 37,330,591 (GRCm39)	Y1002N	probably damaging	Het
Svep1	A	T	4: 58,145,156 (GRCm39)		probably null	Het
Thsd7a	A	G	6: 12,331,548 (GRCm39)	V1342A	probably damaging	Het
Tmtc3	A	C	10: 100,284,888 (GRCm39)	N582K	probably damaging	Het
Tnfrsf11b	G	A	15: 54,119,578 (GRCm39)		probably benign	Het
Trim30a	A	G	7: 104,060,348 (GRCm39)	V476A	probably damaging	Het
Ugt1a8	A	G	1: 88,015,770 (GRCm39)	E61G	possibly damaging	Het
Vmn1r75	A	T	7: 11,614,757 (GRCm39)	N163I	possibly damaging	Het
Vps35l	A	G	7: 118,345,613 (GRCm39)	T49A	possibly damaging	Het
Zfp119a	G	A	17: 56,173,520 (GRCm39)	L108F	probably benign	Het

Other mutations in Gm7104

Allele	Source	Chr	Coord	Type	Predicted Effect
R0630:Gm7104	UTSW	12	88,252,479 (GRCm39)	unclassified	noncoding transcript
R1485:Gm7104	UTSW	12	88,252,333 (GRCm39)	unclassified	noncoding transcript
R2044:Gm7104	UTSW	12	88,252,551 (GRCm39)	unclassified	noncoding transcript
R2567:Gm7104	UTSW	12	88,252,242 (GRCm39)	unclassified	noncoding transcript
R3177:Gm7104	UTSW	12	88,252,498 (GRCm39)	unclassified	noncoding transcript
R3277:Gm7104	UTSW	12	88,252,498 (GRCm39)	unclassified	noncoding transcript
R3778:Gm7104	UTSW	12	88,252,441 (GRCm39)	unclassified	noncoding transcript
R3946:Gm7104	UTSW	12	88,252,812 (GRCm39)	unclassified	noncoding transcript
R4754:Gm7104	UTSW	12	88,252,765 (GRCm39)	unclassified	noncoding transcript
R5022:Gm7104	UTSW	12	88,252,529 (GRCm39)	unclassified	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- ACCTGAAGCAAAAGCTCTGG -3'
(R):5'- TCATTGGACACAGCCTGGAG -3'

Sequencing Primer
(F):5'- AGGCATGTGGTCAGCTATCAC -3'
(R):5'- GAGCGACCTACTGGCTCTCAAAG -3'

Posted On

2015-04-17