Incidental Mutation 'R4852:Rgl2'
| ID |
373674 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rgl2
|
| Ensembl Gene |
ENSMUSG00000041354 |
| Gene Name |
ral guanine nucleotide dissociation stimulator-like 2 |
| Synonyms |
Rlf, Rgt2, Rab2l, KE1.5 |
| MMRRC Submission |
042464-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.136)
|
| Stock # |
R4852 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
34148813-34156661 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 34156147 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Arginine
at position 745
(H745R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000041082
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000025163]
[ENSMUST00000025170]
[ENSMUST00000047503]
[ENSMUST00000173363]
[ENSMUST00000174048]
[ENSMUST00000179418]
[ENSMUST00000174426]
|
| AlphaFold |
Q61193 |
| PDB Structure |
STRUCTURE DETERMINATION OF THE RAS-BINDING DOMAIN OF THE RAL-SPECIFIC GUANINE NUCLEOTIDE EXCHANGE FACTOR RLF, NMR, 10 STRUCTURES [SOLUTION NMR]
The conformation of a docking site for SH3 domains is pre-selected in the Guanine Nucleotide Exchange Factor Rlf [X-RAY DIFFRACTION]
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000025163
|
| SMART Domains |
Protein: ENSMUSP00000025163
Gene: ENSMUSG00000024309
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Prefoldin_2
|
10 |
115 |
9.6e-29 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000025170
|
| SMART Domains |
Protein: ENSMUSP00000025170
Gene: ENSMUSG00000024312
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
126 |
155 |
N/A |
INTRINSIC |
|
low complexity region
|
204 |
217 |
N/A |
INTRINSIC |
|
WD40
|
225 |
262 |
1.02e2 |
SMART |
|
WD40
|
267 |
302 |
3.3e1 |
SMART |
|
Blast:WD40
|
305 |
344 |
8e-19 |
BLAST |
|
WD40
|
347 |
386 |
9.52e-6 |
SMART |
|
Blast:WD40
|
392 |
426 |
3e-14 |
BLAST |
|
BING4CT
|
439 |
517 |
8.85e-53 |
SMART |
|
low complexity region
|
542 |
556 |
N/A |
INTRINSIC |
|
low complexity region
|
586 |
593 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000047503
AA Change: H745R
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000041082
Gene: ENSMUSG00000041354
AA Change: H745R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
15 |
N/A |
INTRINSIC |
|
low complexity region
|
31 |
42 |
N/A |
INTRINSIC |
|
low complexity region
|
44 |
63 |
N/A |
INTRINSIC |
|
RasGEFN
|
87 |
212 |
9.54e-30 |
SMART |
|
RasGEF
|
239 |
514 |
7.15e-106 |
SMART |
|
low complexity region
|
578 |
592 |
N/A |
INTRINSIC |
|
low complexity region
|
602 |
619 |
N/A |
INTRINSIC |
|
low complexity region
|
633 |
648 |
N/A |
INTRINSIC |
|
RA
|
649 |
736 |
2.05e-19 |
SMART |
|
low complexity region
|
737 |
762 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000172546
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000173153
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000173258
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000173266
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000173284
AA Change: H297R
|
| SMART Domains |
Protein: ENSMUSP00000134312
Gene: ENSMUSG00000041354
AA Change: H297R
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:RasGEF
|
2 |
67 |
1e-35 |
BLAST |
|
PDB:4JGW|B
|
2 |
67 |
1e-35 |
PDB |
|
SCOP:d1bkds_
|
2 |
94 |
3e-16 |
SMART |
|
low complexity region
|
131 |
145 |
N/A |
INTRINSIC |
|
low complexity region
|
155 |
172 |
N/A |
INTRINSIC |
|
low complexity region
|
186 |
201 |
N/A |
INTRINSIC |
|
RA
|
202 |
289 |
2.05e-19 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000173857
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000173678
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000173502
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000173718
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000174442
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000173379
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000173363
|
| SMART Domains |
Protein: ENSMUSP00000138662
Gene: ENSMUSG00000024309
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Prefoldin_2
|
1 |
89 |
1.1e-24 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000174048
|
| SMART Domains |
Protein: ENSMUSP00000133656
Gene: ENSMUSG00000024309
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Prefoldin_2
|
10 |
115 |
2e-28 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000179418
|
| SMART Domains |
Protein: ENSMUSP00000137072
Gene: ENSMUSG00000024309
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Prefoldin_2
|
10 |
115 |
2e-28 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000174426
|
| SMART Domains |
Protein: ENSMUSP00000134069
Gene: ENSMUSG00000024309
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Prefoldin_2
|
1 |
89 |
1.1e-24 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.2%
- 20x: 92.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2700049A03Rik |
G |
T |
12: 71,211,320 (GRCm39) |
E685* |
probably null |
Het |
| 2700049A03Rik |
A |
T |
12: 71,211,321 (GRCm39) |
E685V |
possibly damaging |
Het |
| 4921524L21Rik |
C |
G |
18: 6,623,487 (GRCm39) |
L66V |
possibly damaging |
Het |
| 4921524L21Rik |
T |
A |
18: 6,623,488 (GRCm39) |
L66Q |
probably damaging |
Het |
| Abca6 |
A |
G |
11: 110,135,029 (GRCm39) |
V252A |
probably benign |
Het |
| Ablim2 |
C |
T |
5: 35,959,766 (GRCm39) |
R73C |
possibly damaging |
Het |
| Acap1 |
C |
T |
11: 69,775,202 (GRCm39) |
V354M |
probably benign |
Het |
| Accs |
T |
C |
2: 93,674,605 (GRCm39) |
D99G |
probably damaging |
Het |
| Adam9 |
T |
C |
8: 25,493,317 (GRCm39) |
Y97C |
probably damaging |
Het |
| Akap6 |
T |
C |
12: 53,151,458 (GRCm39) |
V1174A |
probably damaging |
Het |
| Aknad1 |
C |
A |
3: 108,659,056 (GRCm39) |
D23E |
probably damaging |
Het |
| Ano2 |
T |
C |
6: 125,959,886 (GRCm39) |
C666R |
possibly damaging |
Het |
| Atp4a |
G |
A |
7: 30,423,693 (GRCm39) |
A933T |
probably benign |
Het |
| Atxn2 |
T |
C |
5: 121,952,474 (GRCm39) |
L224P |
probably damaging |
Het |
| Bin2 |
T |
C |
15: 100,543,169 (GRCm39) |
E338G |
probably damaging |
Het |
| Bloc1s5 |
T |
C |
13: 38,818,960 (GRCm39) |
K20E |
probably damaging |
Het |
| Bst1 |
A |
T |
5: 43,977,867 (GRCm39) |
D72V |
probably benign |
Het |
| Cacna1i |
T |
C |
15: 80,272,680 (GRCm39) |
F1631L |
probably damaging |
Het |
| Capn13 |
GCA |
G |
17: 73,658,501 (GRCm39) |
|
probably null |
Het |
| Cfap43 |
A |
G |
19: 47,885,550 (GRCm39) |
I355T |
possibly damaging |
Het |
| Chuk |
A |
T |
19: 44,077,197 (GRCm39) |
M383K |
possibly damaging |
Het |
| Cnga4 |
A |
G |
7: 105,054,937 (GRCm39) |
I174V |
probably benign |
Het |
| Cpd |
T |
C |
11: 76,675,976 (GRCm39) |
K1226E |
probably benign |
Het |
| Crip2 |
T |
C |
12: 113,104,204 (GRCm39) |
C5R |
probably damaging |
Het |
| Cyp3a11 |
T |
A |
5: 145,797,305 (GRCm39) |
D358V |
probably damaging |
Het |
| Ebag9 |
T |
C |
15: 44,487,915 (GRCm39) |
F21S |
probably damaging |
Het |
| Ercc1 |
A |
T |
7: 19,084,629 (GRCm39) |
H70L |
probably damaging |
Het |
| Exoc3 |
G |
A |
13: 74,347,764 (GRCm39) |
R69C |
probably damaging |
Het |
| Fgfr4 |
A |
T |
13: 55,308,969 (GRCm39) |
R363S |
possibly damaging |
Het |
| Gas2l3 |
CACTCGTCATACT |
CACT |
10: 89,266,820 (GRCm39) |
|
probably benign |
Het |
| Gm7489 |
T |
A |
15: 53,749,434 (GRCm39) |
|
probably benign |
Het |
| Gphn |
G |
A |
12: 78,673,984 (GRCm39) |
V526M |
probably damaging |
Het |
| Gpr152 |
G |
A |
19: 4,193,790 (GRCm39) |
V444I |
probably benign |
Het |
| Gss |
T |
C |
2: 155,406,785 (GRCm39) |
E330G |
probably benign |
Het |
| Hbs1l |
A |
G |
10: 21,234,287 (GRCm39) |
D556G |
possibly damaging |
Het |
| Helz2 |
T |
C |
2: 180,871,913 (GRCm39) |
T2619A |
probably damaging |
Het |
| Hk3 |
A |
G |
13: 55,160,409 (GRCm39) |
F304L |
probably damaging |
Het |
| Itgad |
A |
T |
7: 127,797,702 (GRCm39) |
N906Y |
probably damaging |
Het |
| Jakmip2 |
T |
C |
18: 43,710,465 (GRCm39) |
E246G |
probably damaging |
Het |
| L3mbtl4 |
A |
T |
17: 68,866,748 (GRCm39) |
H329L |
probably damaging |
Het |
| Mau2 |
A |
G |
8: 70,485,827 (GRCm39) |
|
probably null |
Het |
| Myo16 |
T |
C |
8: 10,423,474 (GRCm39) |
L270P |
probably damaging |
Het |
| Naa25 |
T |
C |
5: 121,568,755 (GRCm39) |
S606P |
probably damaging |
Het |
| Nags |
T |
A |
11: 102,037,447 (GRCm39) |
C179* |
probably null |
Het |
| Naip2 |
A |
G |
13: 100,298,044 (GRCm39) |
M664T |
probably benign |
Het |
| Ndufv3 |
T |
C |
17: 31,747,043 (GRCm39) |
I311T |
probably benign |
Het |
| Nipsnap1 |
G |
T |
11: 4,841,468 (GRCm39) |
E258* |
probably null |
Het |
| Nudc |
A |
G |
4: 133,261,660 (GRCm39) |
L208P |
probably damaging |
Het |
| Or1e32 |
T |
C |
11: 73,705,074 (GRCm39) |
Y278C |
probably benign |
Het |
| Or51a39 |
A |
T |
7: 102,362,750 (GRCm39) |
V290E |
probably damaging |
Het |
| Oscp1 |
A |
G |
4: 125,970,652 (GRCm39) |
D137G |
possibly damaging |
Het |
| Pcdhb5 |
C |
T |
18: 37,455,524 (GRCm39) |
P635S |
probably benign |
Het |
| Pcdhgb2 |
T |
A |
18: 37,825,103 (GRCm39) |
I698N |
probably damaging |
Het |
| Pde4b |
A |
G |
4: 102,454,967 (GRCm39) |
Y399C |
probably damaging |
Het |
| Pdf |
A |
T |
8: 107,774,812 (GRCm39) |
V140E |
probably damaging |
Het |
| Pglyrp2 |
T |
C |
17: 32,634,823 (GRCm39) |
N513S |
probably benign |
Het |
| Ranbp2 |
T |
A |
10: 58,312,878 (GRCm39) |
D1199E |
possibly damaging |
Het |
| Rell2 |
G |
T |
18: 38,089,621 (GRCm39) |
|
probably null |
Het |
| Rnf121 |
A |
G |
7: 101,672,592 (GRCm39) |
C264R |
probably damaging |
Het |
| Rnf181 |
A |
G |
6: 72,338,499 (GRCm39) |
F3S |
probably damaging |
Het |
| Rsrc1 |
T |
A |
3: 67,262,935 (GRCm39) |
D296E |
probably damaging |
Het |
| Rubcn |
A |
T |
16: 32,663,678 (GRCm39) |
D319E |
probably damaging |
Het |
| Scaf8 |
T |
C |
17: 3,228,494 (GRCm39) |
S431P |
unknown |
Het |
| Septin11 |
T |
A |
5: 93,310,112 (GRCm39) |
M305K |
possibly damaging |
Het |
| Serpinb12 |
A |
G |
1: 106,884,132 (GRCm39) |
K293E |
probably benign |
Het |
| Sh3bp1 |
T |
A |
15: 78,788,538 (GRCm39) |
H229Q |
probably benign |
Het |
| Slco4c1 |
G |
A |
1: 96,768,953 (GRCm39) |
P303L |
probably damaging |
Het |
| Specc1 |
T |
A |
11: 62,102,510 (GRCm39) |
V952E |
probably damaging |
Het |
| Spint2 |
G |
A |
7: 28,956,211 (GRCm39) |
T158I |
probably benign |
Het |
| St8sia4 |
A |
T |
1: 95,588,623 (GRCm39) |
W71R |
probably damaging |
Het |
| Tex48 |
C |
T |
4: 63,530,151 (GRCm39) |
V23I |
possibly damaging |
Het |
| Tmc5 |
G |
A |
7: 118,244,562 (GRCm39) |
G480D |
probably benign |
Het |
| Tmem8b |
T |
A |
4: 43,689,713 (GRCm39) |
M330K |
probably damaging |
Het |
| Tnrc18 |
C |
T |
5: 142,717,095 (GRCm39) |
R2453Q |
probably damaging |
Het |
| Trank1 |
A |
T |
9: 111,220,963 (GRCm39) |
N2567Y |
possibly damaging |
Het |
| Trps1 |
T |
C |
15: 50,709,705 (GRCm39) |
D211G |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,555,503 (GRCm39) |
R30501G |
probably damaging |
Het |
| Ttn |
T |
A |
2: 76,573,247 (GRCm39) |
Y25882F |
probably damaging |
Het |
| Unc79 |
T |
A |
12: 103,139,725 (GRCm39) |
V2495E |
probably damaging |
Het |
| Uqcr10 |
T |
A |
11: 4,652,198 (GRCm39) |
H58L |
possibly damaging |
Het |
| Usp7 |
A |
T |
16: 8,574,708 (GRCm39) |
C58* |
probably null |
Het |
| Vmn1r36 |
A |
T |
6: 66,693,872 (GRCm39) |
M1K |
probably null |
Het |
| Wdr7 |
T |
A |
18: 63,911,020 (GRCm39) |
M804K |
probably damaging |
Het |
| Zfp131 |
A |
C |
13: 120,250,394 (GRCm39) |
|
probably null |
Het |
| Zfp507 |
A |
G |
7: 35,493,480 (GRCm39) |
V521A |
probably benign |
Het |
|
| Other mutations in Rgl2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00514:Rgl2
|
APN |
17 |
34,152,110 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL00898:Rgl2
|
APN |
17 |
34,152,392 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL00965:Rgl2
|
APN |
17 |
34,154,910 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00985:Rgl2
|
APN |
17 |
34,151,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02140:Rgl2
|
APN |
17 |
34,152,098 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02214:Rgl2
|
APN |
17 |
34,154,163 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02486:Rgl2
|
APN |
17 |
34,154,954 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02579:Rgl2
|
APN |
17 |
34,156,134 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL02976:Rgl2
|
APN |
17 |
34,152,936 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
Hypotenuse
|
UTSW |
17 |
34,150,713 (GRCm39) |
missense |
probably benign |
0.00 |
|
Pedernales
|
UTSW |
17 |
34,151,012 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
PIT4354001:Rgl2
|
UTSW |
17 |
34,152,914 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0347:Rgl2
|
UTSW |
17 |
34,151,712 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0456:Rgl2
|
UTSW |
17 |
34,155,823 (GRCm39) |
splice site |
probably null |
|
|
R0825:Rgl2
|
UTSW |
17 |
34,154,133 (GRCm39) |
splice site |
probably null |
|
|
R1742:Rgl2
|
UTSW |
17 |
34,156,197 (GRCm39) |
splice site |
probably null |
|
|
R1777:Rgl2
|
UTSW |
17 |
34,150,718 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1829:Rgl2
|
UTSW |
17 |
34,152,595 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1908:Rgl2
|
UTSW |
17 |
34,151,122 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1961:Rgl2
|
UTSW |
17 |
34,152,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2102:Rgl2
|
UTSW |
17 |
34,152,314 (GRCm39) |
splice site |
probably null |
|
|
R3001:Rgl2
|
UTSW |
17 |
34,151,579 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3002:Rgl2
|
UTSW |
17 |
34,151,579 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3755:Rgl2
|
UTSW |
17 |
34,151,571 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3756:Rgl2
|
UTSW |
17 |
34,151,571 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3978:Rgl2
|
UTSW |
17 |
34,154,136 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4042:Rgl2
|
UTSW |
17 |
34,156,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4064:Rgl2
|
UTSW |
17 |
34,156,082 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R4204:Rgl2
|
UTSW |
17 |
34,155,906 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4661:Rgl2
|
UTSW |
17 |
34,152,200 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R4922:Rgl2
|
UTSW |
17 |
34,151,749 (GRCm39) |
unclassified |
probably benign |
|
|
R5119:Rgl2
|
UTSW |
17 |
34,156,094 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5167:Rgl2
|
UTSW |
17 |
34,154,948 (GRCm39) |
nonsense |
probably null |
|
|
R5279:Rgl2
|
UTSW |
17 |
34,154,922 (GRCm39) |
missense |
probably benign |
|
|
R5319:Rgl2
|
UTSW |
17 |
34,152,529 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5337:Rgl2
|
UTSW |
17 |
34,153,958 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5881:Rgl2
|
UTSW |
17 |
34,151,691 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5945:Rgl2
|
UTSW |
17 |
34,151,012 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6165:Rgl2
|
UTSW |
17 |
34,150,739 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6358:Rgl2
|
UTSW |
17 |
34,156,105 (GRCm39) |
splice site |
probably null |
|
|
R6867:Rgl2
|
UTSW |
17 |
34,151,661 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7174:Rgl2
|
UTSW |
17 |
34,153,964 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7182:Rgl2
|
UTSW |
17 |
34,153,964 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7183:Rgl2
|
UTSW |
17 |
34,153,964 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7184:Rgl2
|
UTSW |
17 |
34,153,964 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7196:Rgl2
|
UTSW |
17 |
34,152,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7203:Rgl2
|
UTSW |
17 |
34,152,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7250:Rgl2
|
UTSW |
17 |
34,152,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7253:Rgl2
|
UTSW |
17 |
34,153,964 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7254:Rgl2
|
UTSW |
17 |
34,153,964 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7255:Rgl2
|
UTSW |
17 |
34,153,964 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7256:Rgl2
|
UTSW |
17 |
34,153,964 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7282:Rgl2
|
UTSW |
17 |
34,152,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7455:Rgl2
|
UTSW |
17 |
34,151,657 (GRCm39) |
missense |
probably benign |
0.32 |
|
R7513:Rgl2
|
UTSW |
17 |
34,151,529 (GRCm39) |
missense |
probably benign |
|
|
R7752:Rgl2
|
UTSW |
17 |
34,154,799 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7901:Rgl2
|
UTSW |
17 |
34,154,799 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7941:Rgl2
|
UTSW |
17 |
34,150,713 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8158:Rgl2
|
UTSW |
17 |
34,155,918 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8209:Rgl2
|
UTSW |
17 |
34,151,501 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R8226:Rgl2
|
UTSW |
17 |
34,151,501 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R8405:Rgl2
|
UTSW |
17 |
34,152,698 (GRCm39) |
nonsense |
probably null |
|
|
R8871:Rgl2
|
UTSW |
17 |
34,153,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9205:Rgl2
|
UTSW |
17 |
34,155,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9591:Rgl2
|
UTSW |
17 |
34,151,451 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
X0028:Rgl2
|
UTSW |
17 |
34,151,432 (GRCm39) |
splice site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CTGTGGCTTCAGAGTTCGAG -3'
(R):5'- TATTGTGGCCACCATGTGTG -3'
Sequencing Primer
(F):5'- CAGAGTTCGAGCTGGTGCAG -3'
(R):5'- GGCTGCTCACTCCTGGTATGAG -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation