Mutagenetix > Incidental Mutation

Incidental Mutation 'R4044:Or5h24'

475373

Institutional Source

Beutler Lab

Gene Symbol

Or5h24

Ensembl Gene

ENSMUSG00000059041

Gene Name

olfactory receptor family 5 subfamily H member 24, pseudogene 1

Synonyms

Olfr192, MOR183-11_p, GA_x54KRFPKG5P-55327126-55326203

MMRRC Submission

040967-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.185) question?

Stock #

R4044 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

58918429-58922216 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 58919124 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Isoleucine at position 77 (T77I)

Ref Sequence

ENSEMBL: ENSMUSP00000145941 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000080251] [ENSMUST00000205727] [ENSMUST00000206214]

AlphaFold

no structure available at present

Predicted Effect

unknown
Transcript: ENSMUST00000080251
AA Change: T77I

Predicted Effect

unknown
Transcript: ENSMUST00000205727
AA Change: T77I

Predicted Effect

unknown
Transcript: ENSMUST00000206214
AA Change: T77I

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.1%
20x: 94.5%

Validation Efficiency

100% (45/45)

Allele List at MGI

Other mutations in this stock

Total: 43 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930579C12Rik	T	A	9: 89,044,347 (GRCm39)		noncoding transcript	Het
Ada	A	T	2: 163,577,380 (GRCm39)	I36N	probably damaging	Het
Armh3	A	T	19: 45,808,763 (GRCm39)	Y643N	probably damaging	Het
Atg7	T	C	6: 114,678,939 (GRCm39)	V384A	probably benign	Het
Ccl1	T	A	11: 82,070,519 (GRCm39)	I18L	probably benign	Het
Cep70	T	A	9: 99,144,662 (GRCm39)	C66S	possibly damaging	Het
D16Ertd472e	A	T	16: 78,372,894 (GRCm39)	D14E	probably damaging	Het
Dnah9	T	C	11: 66,024,461 (GRCm39)	K278E	probably benign	Het
Dsg1a	C	A	18: 20,457,087 (GRCm39)	N153K	probably damaging	Het
Galnt5	T	A	2: 57,888,472 (GRCm39)	I24N	probably damaging	Het
Grid1	A	T	14: 35,172,358 (GRCm39)		probably benign	Het
Gtf2a1	T	C	12: 91,542,441 (GRCm39)	H47R	probably benign	Het
Igf1r	A	G	7: 67,839,810 (GRCm39)	T706A	possibly damaging	Het
Itih4	A	T	14: 30,616,995 (GRCm39)	N517I	probably damaging	Het
Jam3	C	A	9: 27,013,159 (GRCm39)		probably null	Het
Katnip	A	G	7: 125,467,913 (GRCm39)	I1366V	probably benign	Het
Klk1b4	A	G	7: 43,860,179 (GRCm39)	M98V	probably benign	Het
Kndc1	A	G	7: 139,504,044 (GRCm39)	E1116G	probably benign	Het
Ksr2	C	T	5: 117,693,127 (GRCm39)	R192*	probably null	Het
L3mbtl4	T	C	17: 69,084,909 (GRCm39)	S607P	possibly damaging	Het
Map6	T	C	7: 98,917,256 (GRCm39)	C10R	probably damaging	Het
Myo3a	A	G	2: 22,467,712 (GRCm39)	E322G	probably damaging	Het
Nell1	A	G	7: 49,869,367 (GRCm39)	N214S	probably damaging	Het
Npm3	T	C	19: 45,736,692 (GRCm39)	E149G	possibly damaging	Het
Or4k35	C	T	2: 111,099,927 (GRCm39)	V262I	probably benign	Het
Orc3	G	A	4: 34,587,055 (GRCm39)	Q345*	probably null	Het
Otol1	A	G	3: 69,935,112 (GRCm39)	D368G	probably damaging	Het
Pals1	G	A	12: 78,871,613 (GRCm39)	E398K	probably benign	Het
Pramel26	T	A	4: 143,538,170 (GRCm39)	N267I	probably benign	Het
Prss40	G	T	1: 34,599,960 (GRCm39)	S9*	probably null	Het
Radx	C	T	X: 138,407,752 (GRCm39)	S364L	probably damaging	Het
Reln	A	T	5: 22,333,630 (GRCm39)	V264D	possibly damaging	Het
Rpp40	A	G	13: 36,082,549 (GRCm39)	C275R	probably benign	Het
Scaf1	G	A	7: 44,655,798 (GRCm39)		probably benign	Het
Sncaip	A	G	18: 53,040,475 (GRCm39)	T890A	probably benign	Het
Spata6l	A	T	19: 28,923,183 (GRCm39)	C80S	possibly damaging	Het
Thada	A	G	17: 84,749,135 (GRCm39)	V612A	probably benign	Het
Tsnaxip1	G	A	8: 106,560,177 (GRCm39)		probably null	Het
Vcan	T	A	13: 89,840,662 (GRCm39)	L1627F	probably benign	Het
Vrtn	T	C	12: 84,695,844 (GRCm39)	I198T	probably damaging	Het
Wnt9b	T	C	11: 103,622,824 (GRCm39)	D193G	probably damaging	Het
Znrd2	T	C	19: 5,780,431 (GRCm39)	E189G	probably damaging	Het
Zswim5	A	G	4: 116,843,899 (GRCm39)	D979G	probably damaging	Het

Other mutations in Or5h24

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R3807:Or5h24	UTSW	16	58,919,206 (GRCm39)	makesense	probably null
R3872:Or5h24	UTSW	16	58,919,124 (GRCm39)	missense	unknown
R4008:Or5h24	UTSW	16	58,919,124 (GRCm39)	missense	unknown
R4009:Or5h24	UTSW	16	58,919,124 (GRCm39)	missense	unknown
R4011:Or5h24	UTSW	16	58,919,124 (GRCm39)	missense	unknown
R4043:Or5h24	UTSW	16	58,919,124 (GRCm39)	missense	unknown
R4296:Or5h24	UTSW	16	58,919,124 (GRCm39)	missense	unknown
R4300:Or5h24	UTSW	16	58,918,641 (GRCm39)	missense	unknown
R4948:Or5h24	UTSW	16	58,919,340 (GRCm39)	missense	probably damaging	0.99
R5411:Or5h24	UTSW	16	58,919,067 (GRCm39)	missense	unknown
R5426:Or5h24	UTSW	16	58,918,665 (GRCm39)	missense	possibly damaging	0.93
R5436:Or5h24	UTSW	16	58,919,182 (GRCm39)	missense	unknown
R5597:Or5h24	UTSW	16	58,918,710 (GRCm39)	missense	unknown
R6758:Or5h24	UTSW	16	58,919,328 (GRCm39)	missense	probably damaging	0.96
R6882:Or5h24	UTSW	16	58,918,990 (GRCm39)	missense	unknown
R8026:Or5h24	UTSW	16	58,918,731 (GRCm39)	missense	unknown
R8224:Or5h24	UTSW	16	58,919,117 (GRCm39)	missense	unknown
R8313:Or5h24	UTSW	16	58,919,004 (GRCm39)	missense	unknown
R8827:Or5h24	UTSW	16	58,919,061 (GRCm39)	missense	unknown

Predicted Primers

Posted On

2017-04-14