Incidental Mutation 'R7391:Wdr90'
| ID |
573468 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Wdr90
|
| Ensembl Gene |
ENSMUSG00000073434 |
| Gene Name |
WD repeat domain 90 |
| Synonyms |
3230401M21Rik |
| MMRRC Submission |
045473-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.101)
|
| Stock # |
R7391 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
26063745-26080475 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 26065502 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Serine
at position 1621
(N1621S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000078426
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043897]
[ENSMUST00000079461]
[ENSMUST00000176709]
[ENSMUST00000176923]
|
| AlphaFold |
Q6ZPG2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000043897
|
| SMART Domains |
Protein: ENSMUSP00000044639
Gene: ENSMUSG00000025733
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Roc
|
6 |
122 |
4.1e-11 |
PFAM |
|
Pfam:Ras
|
6 |
168 |
2.3e-18 |
PFAM |
|
EFh
|
188 |
216 |
1.27e1 |
SMART |
|
Pfam:EF_assoc_2
|
219 |
305 |
2.2e-35 |
PFAM |
|
EFh
|
308 |
336 |
1.23e-1 |
SMART |
|
Pfam:EF_assoc_1
|
341 |
412 |
1.8e-25 |
PFAM |
|
Blast:AAA
|
416 |
547 |
7e-18 |
BLAST |
|
SCOP:d1mh1__
|
422 |
532 |
4e-8 |
SMART |
|
transmembrane domain
|
595 |
617 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000079461
AA Change: N1621S
PolyPhen 2
Score 0.078 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000078426
Gene: ENSMUSG00000073434
AA Change: N1621S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
53 |
N/A |
INTRINSIC |
|
Pfam:DUF667
|
60 |
183 |
5e-26 |
PFAM |
|
Pfam:DUF667
|
210 |
271 |
3.7e-9 |
PFAM |
|
low complexity region
|
381 |
396 |
N/A |
INTRINSIC |
|
WD40
|
478 |
519 |
5.94e0 |
SMART |
|
WD40
|
522 |
565 |
3.2e0 |
SMART |
|
WD40
|
572 |
612 |
3.3e1 |
SMART |
|
WD40
|
687 |
725 |
1.15e1 |
SMART |
|
WD40
|
728 |
766 |
5.75e-1 |
SMART |
|
WD40
|
768 |
808 |
9.24e-4 |
SMART |
|
WD40
|
811 |
850 |
4.13e0 |
SMART |
|
WD40
|
853 |
892 |
4.62e-1 |
SMART |
|
WD40
|
950 |
993 |
1.07e1 |
SMART |
|
WD40
|
996 |
1035 |
5.75e-1 |
SMART |
|
WD40
|
1040 |
1077 |
1.58e-2 |
SMART |
|
WD40
|
1290 |
1334 |
5.23e-3 |
SMART |
|
WD40
|
1337 |
1378 |
1.27e-1 |
SMART |
|
WD40
|
1384 |
1419 |
1.83e2 |
SMART |
|
WD40
|
1422 |
1469 |
3.08e0 |
SMART |
|
WD40
|
1472 |
1509 |
9.9e0 |
SMART |
|
WD40
|
1568 |
1607 |
9.02e-7 |
SMART |
|
WD40
|
1610 |
1655 |
5.75e-1 |
SMART |
|
WD40
|
1659 |
1697 |
2.98e-1 |
SMART |
|
WD40
|
1700 |
1749 |
6.14e1 |
SMART |
|
WD40
|
1850 |
1888 |
1.92e-1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176591
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176709
|
| SMART Domains |
Protein: ENSMUSP00000135436
Gene: ENSMUSG00000025733
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Arf
|
1 |
121 |
1.6e-6 |
PFAM |
|
Pfam:MMR_HSR1
|
6 |
118 |
1.4e-6 |
PFAM |
|
Pfam:Miro
|
6 |
120 |
7.8e-20 |
PFAM |
|
Pfam:Ras
|
6 |
121 |
7.2e-16 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176751
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000176923
AA Change: N1603S
PolyPhen 2
Score 0.907 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000135420
Gene: ENSMUSG00000073434
AA Change: N1603S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
53 |
N/A |
INTRINSIC |
|
Pfam:DUF667
|
60 |
252 |
5.1e-14 |
PFAM |
|
low complexity region
|
363 |
378 |
N/A |
INTRINSIC |
|
WD40
|
460 |
501 |
5.94e0 |
SMART |
|
WD40
|
504 |
547 |
3.2e0 |
SMART |
|
WD40
|
554 |
594 |
3.3e1 |
SMART |
|
WD40
|
669 |
707 |
1.15e1 |
SMART |
|
WD40
|
710 |
748 |
5.75e-1 |
SMART |
|
WD40
|
750 |
790 |
9.24e-4 |
SMART |
|
WD40
|
793 |
832 |
4.13e0 |
SMART |
|
WD40
|
835 |
874 |
4.62e-1 |
SMART |
|
WD40
|
932 |
975 |
1.07e1 |
SMART |
|
WD40
|
978 |
1017 |
5.75e-1 |
SMART |
|
WD40
|
1022 |
1059 |
1.58e-2 |
SMART |
|
WD40
|
1272 |
1316 |
5.23e-3 |
SMART |
|
WD40
|
1319 |
1360 |
1.27e-1 |
SMART |
|
WD40
|
1366 |
1401 |
1.83e2 |
SMART |
|
WD40
|
1404 |
1451 |
3.08e0 |
SMART |
|
WD40
|
1454 |
1491 |
9.9e0 |
SMART |
|
WD40
|
1550 |
1589 |
9.02e-7 |
SMART |
|
WD40
|
1592 |
1637 |
5.75e-1 |
SMART |
|
WD40
|
1641 |
1679 |
2.98e-1 |
SMART |
|
WD40
|
1682 |
1731 |
6.14e1 |
SMART |
|
WD40
|
1832 |
1870 |
1.92e-1 |
SMART |
|
| Meta Mutation Damage Score |
0.0751 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
99% (79/80) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Arfgef3 |
A |
T |
10: 18,522,007 (GRCm39) |
I673K |
probably benign |
Het |
| Arhgap32 |
C |
A |
9: 32,093,235 (GRCm39) |
T196K |
probably benign |
Het |
| Azi2 |
T |
A |
9: 117,879,960 (GRCm39) |
|
probably null |
Het |
| B3gnt2 |
A |
T |
11: 22,786,482 (GRCm39) |
C235* |
probably null |
Het |
| Capn5 |
C |
T |
7: 97,780,426 (GRCm39) |
V315M |
probably benign |
Het |
| Ccl24 |
T |
A |
5: 135,599,676 (GRCm39) |
R111S |
possibly damaging |
Het |
| Cdk9 |
A |
G |
2: 32,602,083 (GRCm39) |
V45A |
probably damaging |
Het |
| Cep162 |
G |
T |
9: 87,130,547 (GRCm39) |
S21* |
probably null |
Het |
| Chil3 |
T |
A |
3: 106,071,496 (GRCm39) |
Y56F |
probably damaging |
Het |
| Ctr9 |
T |
A |
7: 110,642,378 (GRCm39) |
L368* |
probably null |
Het |
| Ctss |
A |
G |
3: 95,436,852 (GRCm39) |
E45G |
probably benign |
Het |
| Cyp2c29 |
A |
T |
19: 39,296,211 (GRCm39) |
Q214L |
probably null |
Het |
| Cyp2d34 |
T |
A |
15: 82,502,587 (GRCm39) |
N183I |
probably benign |
Het |
| Dhx29 |
T |
A |
13: 113,099,393 (GRCm39) |
N1139K |
probably benign |
Het |
| Elp1 |
C |
A |
4: 56,781,211 (GRCm39) |
Q487H |
possibly damaging |
Het |
| Elp1 |
T |
G |
4: 56,781,212 (GRCm39) |
Q487P |
probably benign |
Het |
| Ermp1 |
C |
A |
19: 29,604,468 (GRCm39) |
|
probably null |
Het |
| Ermp1 |
T |
A |
19: 29,604,469 (GRCm39) |
|
probably null |
Het |
| Evi2 |
A |
G |
11: 79,406,493 (GRCm39) |
S361P |
probably benign |
Het |
| Ext2 |
T |
A |
2: 93,560,612 (GRCm39) |
K518M |
probably damaging |
Het |
| Fgl1 |
A |
C |
8: 41,663,483 (GRCm39) |
M15R |
probably benign |
Het |
| Fsip2 |
T |
G |
2: 82,820,663 (GRCm39) |
D5465E |
possibly damaging |
Het |
| Hdlbp |
A |
T |
1: 93,358,783 (GRCm39) |
I256N |
possibly damaging |
Het |
| Hmmr |
G |
T |
11: 40,598,613 (GRCm39) |
|
probably null |
Het |
| Hnrnpu |
T |
C |
1: 178,164,643 (GRCm39) |
Q165R |
unknown |
Het |
| Homer3 |
G |
A |
8: 70,742,134 (GRCm39) |
A132T |
probably benign |
Het |
| Ift70a1 |
T |
C |
2: 75,810,359 (GRCm39) |
K575E |
probably benign |
Het |
| Kcnb1 |
T |
C |
2: 166,947,370 (GRCm39) |
R493G |
probably damaging |
Het |
| Kcnn3 |
A |
T |
3: 89,516,778 (GRCm39) |
T396S |
probably benign |
Het |
| Krt15 |
A |
T |
11: 100,026,386 (GRCm39) |
V100E |
possibly damaging |
Het |
| Krtap4-1 |
A |
G |
11: 99,518,810 (GRCm39) |
S67P |
unknown |
Het |
| Lama4 |
G |
T |
10: 38,963,383 (GRCm39) |
|
probably null |
Het |
| Lrrtm2 |
T |
A |
18: 35,345,818 (GRCm39) |
I495F |
possibly damaging |
Het |
| Mical2 |
A |
T |
7: 111,919,816 (GRCm39) |
E442V |
probably damaging |
Het |
| Muc16 |
C |
T |
9: 18,550,832 (GRCm39) |
V5154I |
probably benign |
Het |
| Nav3 |
A |
T |
10: 109,539,317 (GRCm39) |
M2028K |
probably benign |
Het |
| Ncr1 |
T |
A |
7: 4,347,470 (GRCm39) |
W249R |
possibly damaging |
Het |
| Neurod6 |
T |
C |
6: 55,656,616 (GRCm39) |
D7G |
probably damaging |
Het |
| Nwd1 |
A |
G |
8: 73,389,046 (GRCm39) |
E158G |
probably damaging |
Het |
| Or10ak7 |
A |
T |
4: 118,791,198 (GRCm39) |
N282K |
possibly damaging |
Het |
| Or2h15 |
A |
T |
17: 38,441,941 (GRCm39) |
F47L |
probably benign |
Het |
| Or2t26 |
A |
G |
11: 49,039,806 (GRCm39) |
T241A |
probably damaging |
Het |
| Or2y11 |
T |
C |
11: 49,443,371 (GRCm39) |
S266P |
probably damaging |
Het |
| Or51a39 |
T |
C |
7: 102,363,189 (GRCm39) |
N144D |
probably benign |
Het |
| Padi2 |
A |
G |
4: 140,665,266 (GRCm39) |
D457G |
probably benign |
Het |
| Parn |
C |
A |
16: 13,485,870 (GRCm39) |
|
probably null |
Het |
| Pcdh1 |
C |
T |
18: 38,335,838 (GRCm39) |
E266K |
possibly damaging |
Het |
| Pigr |
A |
G |
1: 130,777,303 (GRCm39) |
D703G |
probably damaging |
Het |
| Ppm1f |
T |
A |
16: 16,732,098 (GRCm39) |
S183T |
probably benign |
Het |
| Ppp2r5b |
T |
A |
19: 6,278,544 (GRCm39) |
Q455L |
probably benign |
Het |
| Pramel20 |
T |
A |
4: 143,298,876 (GRCm39) |
L273H |
probably damaging |
Het |
| Ptpn13 |
C |
T |
5: 103,688,847 (GRCm39) |
S880L |
probably damaging |
Het |
| R3hdm4 |
T |
C |
10: 79,746,943 (GRCm39) |
K240R |
probably benign |
Het |
| Rin1 |
T |
C |
19: 5,100,888 (GRCm39) |
M1T |
probably null |
Het |
| Rundc3b |
T |
A |
5: 8,609,455 (GRCm39) |
M170L |
probably benign |
Het |
| Ryr3 |
A |
T |
2: 112,611,322 (GRCm39) |
|
probably null |
Het |
| Scn11a |
T |
C |
9: 119,624,783 (GRCm39) |
D513G |
probably damaging |
Het |
| Slc27a2 |
C |
A |
2: 126,395,082 (GRCm39) |
P3Q |
unknown |
Het |
| Slc4a8 |
A |
G |
15: 100,682,743 (GRCm39) |
I187M |
probably damaging |
Het |
| Slc6a11 |
A |
T |
6: 114,215,422 (GRCm39) |
I441F |
probably benign |
Het |
| Stx2 |
C |
T |
5: 129,065,867 (GRCm39) |
R263Q |
probably damaging |
Het |
| Svep1 |
A |
T |
4: 58,145,185 (GRCm39) |
W427R |
probably damaging |
Het |
| Tes |
T |
A |
6: 17,096,166 (GRCm39) |
H51Q |
probably damaging |
Het |
| Thnsl2 |
T |
C |
6: 71,108,914 (GRCm39) |
D299G |
probably damaging |
Het |
| Tmem30b |
T |
C |
12: 73,592,702 (GRCm39) |
S138G |
probably benign |
Het |
| Tmprss11c |
T |
A |
5: 86,385,650 (GRCm39) |
H274L |
probably damaging |
Het |
| Trim10 |
G |
A |
17: 37,180,773 (GRCm39) |
M1I |
probably null |
Het |
| Unc13b |
A |
G |
4: 43,216,459 (GRCm39) |
I253V |
probably benign |
Het |
| Unc80 |
A |
G |
1: 66,734,687 (GRCm39) |
S3305G |
probably benign |
Het |
| Ush2a |
TCACC |
TC |
1: 188,694,205 (GRCm39) |
|
probably benign |
Het |
| Virma |
A |
G |
4: 11,508,099 (GRCm39) |
D267G |
probably damaging |
Het |
| Vmn1r46 |
C |
T |
6: 89,953,607 (GRCm39) |
S152L |
probably benign |
Het |
| Zfhx3 |
G |
A |
8: 109,674,475 (GRCm39) |
A1842T |
probably damaging |
Het |
| Zfp583 |
A |
G |
7: 6,319,498 (GRCm39) |
S505P |
probably damaging |
Het |
| Zfp608 |
T |
C |
18: 55,030,619 (GRCm39) |
Y1107C |
possibly damaging |
Het |
| Zfp616 |
A |
G |
11: 73,976,155 (GRCm39) |
H808R |
probably benign |
Het |
| Zfp677 |
T |
C |
17: 21,618,653 (GRCm39) |
F570S |
possibly damaging |
Het |
| Zfp85 |
A |
T |
13: 67,897,410 (GRCm39) |
Y221N |
probably damaging |
Het |
|
| Other mutations in Wdr90 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00418:Wdr90
|
APN |
17 |
26,068,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01118:Wdr90
|
APN |
17 |
26,073,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01964:Wdr90
|
APN |
17 |
26,067,383 (GRCm39) |
missense |
probably benign |
|
|
IGL02116:Wdr90
|
APN |
17 |
26,078,466 (GRCm39) |
missense |
probably benign |
0.12 |
|
IGL02172:Wdr90
|
APN |
17 |
26,069,408 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL02716:Wdr90
|
APN |
17 |
26,076,194 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02961:Wdr90
|
APN |
17 |
26,067,649 (GRCm39) |
nonsense |
probably null |
|
|
IGL03229:Wdr90
|
APN |
17 |
26,064,437 (GRCm39) |
splice site |
probably benign |
|
|
IGL03367:Wdr90
|
APN |
17 |
26,066,765 (GRCm39) |
splice site |
probably benign |
|
|
IGL03098:Wdr90
|
UTSW |
17 |
26,078,961 (GRCm39) |
intron |
probably benign |
|
|
R0111:Wdr90
|
UTSW |
17 |
26,067,418 (GRCm39) |
splice site |
probably benign |
|
|
R0454:Wdr90
|
UTSW |
17 |
26,079,023 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0457:Wdr90
|
UTSW |
17 |
26,079,459 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0488:Wdr90
|
UTSW |
17 |
26,067,591 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0622:Wdr90
|
UTSW |
17 |
26,074,632 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0671:Wdr90
|
UTSW |
17 |
26,065,367 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0799:Wdr90
|
UTSW |
17 |
26,079,104 (GRCm39) |
missense |
probably benign |
0.38 |
|
R1177:Wdr90
|
UTSW |
17 |
26,065,028 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1460:Wdr90
|
UTSW |
17 |
26,079,422 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1468:Wdr90
|
UTSW |
17 |
26,073,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1468:Wdr90
|
UTSW |
17 |
26,073,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1544:Wdr90
|
UTSW |
17 |
26,068,284 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R2057:Wdr90
|
UTSW |
17 |
26,074,173 (GRCm39) |
missense |
probably benign |
0.05 |
|
R2087:Wdr90
|
UTSW |
17 |
26,065,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2159:Wdr90
|
UTSW |
17 |
26,070,715 (GRCm39) |
missense |
probably benign |
|
|
R2208:Wdr90
|
UTSW |
17 |
26,079,362 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2345:Wdr90
|
UTSW |
17 |
26,078,136 (GRCm39) |
missense |
probably benign |
0.05 |
|
R2391:Wdr90
|
UTSW |
17 |
26,070,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2394:Wdr90
|
UTSW |
17 |
26,070,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2520:Wdr90
|
UTSW |
17 |
26,074,326 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3798:Wdr90
|
UTSW |
17 |
26,069,472 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3979:Wdr90
|
UTSW |
17 |
26,078,252 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4111:Wdr90
|
UTSW |
17 |
26,068,342 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4326:Wdr90
|
UTSW |
17 |
26,072,705 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4459:Wdr90
|
UTSW |
17 |
26,079,976 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4697:Wdr90
|
UTSW |
17 |
26,074,337 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4735:Wdr90
|
UTSW |
17 |
26,078,424 (GRCm39) |
missense |
probably benign |
|
|
R4907:Wdr90
|
UTSW |
17 |
26,079,624 (GRCm39) |
intron |
probably benign |
|
|
R5070:Wdr90
|
UTSW |
17 |
26,065,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5230:Wdr90
|
UTSW |
17 |
26,074,277 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5268:Wdr90
|
UTSW |
17 |
26,069,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5287:Wdr90
|
UTSW |
17 |
26,080,441 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R5382:Wdr90
|
UTSW |
17 |
26,064,572 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5511:Wdr90
|
UTSW |
17 |
26,063,995 (GRCm39) |
unclassified |
probably benign |
|
|
R5545:Wdr90
|
UTSW |
17 |
26,064,830 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5707:Wdr90
|
UTSW |
17 |
26,076,166 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5973:Wdr90
|
UTSW |
17 |
26,065,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5973:Wdr90
|
UTSW |
17 |
26,064,107 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6385:Wdr90
|
UTSW |
17 |
26,067,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6481:Wdr90
|
UTSW |
17 |
26,064,885 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7078:Wdr90
|
UTSW |
17 |
26,068,623 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7214:Wdr90
|
UTSW |
17 |
26,064,367 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7288:Wdr90
|
UTSW |
17 |
26,065,286 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7304:Wdr90
|
UTSW |
17 |
26,070,480 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7309:Wdr90
|
UTSW |
17 |
26,079,676 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7622:Wdr90
|
UTSW |
17 |
26,073,083 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7646:Wdr90
|
UTSW |
17 |
26,079,104 (GRCm39) |
missense |
probably benign |
0.38 |
|
R7772:Wdr90
|
UTSW |
17 |
26,080,465 (GRCm39) |
start gained |
probably benign |
|
|
R7779:Wdr90
|
UTSW |
17 |
26,065,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7780:Wdr90
|
UTSW |
17 |
26,065,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7781:Wdr90
|
UTSW |
17 |
26,065,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7782:Wdr90
|
UTSW |
17 |
26,065,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7812:Wdr90
|
UTSW |
17 |
26,071,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7870:Wdr90
|
UTSW |
17 |
26,079,513 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7911:Wdr90
|
UTSW |
17 |
26,069,723 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8126:Wdr90
|
UTSW |
17 |
26,067,951 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8260:Wdr90
|
UTSW |
17 |
26,064,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8315:Wdr90
|
UTSW |
17 |
26,064,399 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8919:Wdr90
|
UTSW |
17 |
26,076,146 (GRCm39) |
missense |
|
|
|
R8938:Wdr90
|
UTSW |
17 |
26,076,146 (GRCm39) |
missense |
|
|
|
R8940:Wdr90
|
UTSW |
17 |
26,076,146 (GRCm39) |
missense |
|
|
|
R9038:Wdr90
|
UTSW |
17 |
26,076,200 (GRCm39) |
missense |
|
|
|
R9079:Wdr90
|
UTSW |
17 |
26,076,403 (GRCm39) |
missense |
|
|
|
R9401:Wdr90
|
UTSW |
17 |
26,064,750 (GRCm39) |
small insertion |
probably benign |
|
|
R9471:Wdr90
|
UTSW |
17 |
26,080,015 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R9642:Wdr90
|
UTSW |
17 |
26,072,694 (GRCm39) |
critical splice donor site |
probably null |
|
|
X0064:Wdr90
|
UTSW |
17 |
26,067,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Wdr90
|
UTSW |
17 |
26,079,470 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAGTGTGCCATCGCTGTAGC -3'
(R):5'- GAAGACAGTTGTTCCCGTGTGG -3'
Sequencing Primer
(F):5'- ATCGCTGTAGCCGGCCAC -3'
(R):5'- CAGCCTGGCTTGGAGATCTGAG -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation