Incidental Mutation 'R7527:Myo18a'
ID 583089
Institutional Source Beutler Lab
Gene Symbol Myo18a
Ensembl Gene ENSMUSG00000000631
Gene Name myosin XVIIIA
Synonyms MyoPDZ
MMRRC Submission 045599-MU
Accession Numbers
Essential gene? Essential (E-score: 1.000) question?
Stock # R7527 (G1)
Quality Score 225.009
Status Not validated
Chromosome 11
Chromosomal Location 77654072-77756806 bp(+) (GRCm39)
Type of Mutation missense
DNA Base Change (assembly) T to A at 77734406 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change Cysteine to Serine at position 1476 (C1476S)
Ref Sequence ENSEMBL: ENSMUSP00000130696 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000000645] [ENSMUST00000092884] [ENSMUST00000092887] [ENSMUST00000100794] [ENSMUST00000102488] [ENSMUST00000108375] [ENSMUST00000108376] [ENSMUST00000168348] [ENSMUST00000130305] [ENSMUST00000130627] [ENSMUST00000164334] [ENSMUST00000167856] [ENSMUST00000169105] [ENSMUST00000172303]
AlphaFold Q9JMH9
Predicted Effect probably benign
Transcript: ENSMUST00000000645
AA Change: C1429S

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000000645
Gene: ENSMUSG00000000631
AA Change: C1429S

DomainStartEndE-ValueType
low complexity region 6 27 N/A INTRINSIC
low complexity region 202 227 N/A INTRINSIC
PDZ 229 311 5.72e-10 SMART
MYSc 399 1183 1.53e-45 SMART
IQ 1184 1206 1.11e-3 SMART
Pfam:Myosin_tail_1 1219 1867 1.7e-34 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000092884
AA Change: C1097S

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000090560
Gene: ENSMUSG00000000631
AA Change: C1097S

DomainStartEndE-ValueType
MYSc 68 851 4.16e-47 SMART
IQ 852 874 1.11e-3 SMART
Pfam:Myosin_tail_1 888 1534 2e-34 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000092887
AA Change: C1428S

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000090563
Gene: ENSMUSG00000000631
AA Change: C1428S

DomainStartEndE-ValueType
low complexity region 6 27 N/A INTRINSIC
low complexity region 202 227 N/A INTRINSIC
PDZ 229 311 5.72e-10 SMART
MYSc 399 1182 4.16e-47 SMART
IQ 1183 1205 1.11e-3 SMART
Pfam:Myosin_tail_1 1218 1866 3e-34 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000100794
AA Change: C1093S

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000098358
Gene: ENSMUSG00000000631
AA Change: C1093S

DomainStartEndE-ValueType
MYSc 68 847 1.45e-46 SMART
IQ 848 870 1.11e-3 SMART
Pfam:Myosin_tail_1 884 1530 4.9e-35 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000102488
AA Change: C1428S

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000099546
Gene: ENSMUSG00000000631
AA Change: C1428S

DomainStartEndE-ValueType
low complexity region 6 27 N/A INTRINSIC
low complexity region 202 227 N/A INTRINSIC
PDZ 229 311 5.72e-10 SMART
MYSc 399 1182 4.16e-47 SMART
IQ 1183 1205 1.11e-3 SMART
Pfam:Myosin_tail_1 1218 1866 3e-34 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000108375
AA Change: C1428S

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000104012
Gene: ENSMUSG00000000631
AA Change: C1428S

DomainStartEndE-ValueType
low complexity region 6 27 N/A INTRINSIC
low complexity region 202 227 N/A INTRINSIC
PDZ 229 311 5.72e-10 SMART
MYSc 399 1182 4.16e-47 SMART
IQ 1183 1205 1.11e-3 SMART
Pfam:Myosin_tail_1 1218 1838 6.8e-36 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000108376
AA Change: C1428S

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000104013
Gene: ENSMUSG00000000631
AA Change: C1428S

DomainStartEndE-ValueType
low complexity region 6 27 N/A INTRINSIC
low complexity region 202 227 N/A INTRINSIC
PDZ 229 311 5.72e-10 SMART
MYSc 399 1182 4.16e-47 SMART
IQ 1183 1205 1.11e-3 SMART
Blast:MYSc 1258 1387 1e-14 BLAST
low complexity region 1396 1407 N/A INTRINSIC
low complexity region 1743 1762 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000168348
AA Change: C1476S

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
SMART Domains Protein: ENSMUSP00000130696
Gene: ENSMUSG00000000631
AA Change: C1476S

DomainStartEndE-ValueType
low complexity region 6 27 N/A INTRINSIC
low complexity region 202 227 N/A INTRINSIC
PDZ 229 311 5.72e-10 SMART
MYSc 447 1230 4.16e-47 SMART
IQ 1231 1253 1.11e-3 SMART
Blast:MYSc 1306 1435 1e-14 BLAST
low complexity region 1444 1455 N/A INTRINSIC
low complexity region 1828 1847 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000130305
AA Change: C1109S

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000119574
Gene: ENSMUSG00000000631
AA Change: C1109S

DomainStartEndE-ValueType
MYSc 80 863 4.16e-47 SMART
IQ 864 886 1.11e-3 SMART
Pfam:Myosin_tail_1 902 1547 2.6e-34 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000130627
AA Change: C1440S

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
SMART Domains Protein: ENSMUSP00000119839
Gene: ENSMUSG00000000631
AA Change: C1440S

DomainStartEndE-ValueType
low complexity region 6 27 N/A INTRINSIC
low complexity region 202 227 N/A INTRINSIC
PDZ 229 311 5.72e-10 SMART
MYSc 411 1194 4.16e-47 SMART
IQ 1195 1217 1.11e-3 SMART
Pfam:Myosin_tail_1 1230 1850 6.9e-36 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000164334
AA Change: C1097S

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000131771
Gene: ENSMUSG00000000631
AA Change: C1097S

DomainStartEndE-ValueType
MYSc 68 851 4.16e-47 SMART
IQ 852 874 1.11e-3 SMART
Pfam:Myosin_tail_1 888 1505 4e-36 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000167856
AA Change: C1035S

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
SMART Domains Protein: ENSMUSP00000128487
Gene: ENSMUSG00000000631
AA Change: C1035S

DomainStartEndE-ValueType
MYSc 16 789 1.3e-32 SMART
IQ 790 812 1.11e-3 SMART
Blast:MYSc 865 994 1e-14 BLAST
low complexity region 1003 1014 N/A INTRINSIC
low complexity region 1387 1406 N/A INTRINSIC
internal_repeat_1 1569 1627 2.13e-5 PROSPERO
Predicted Effect probably benign
Transcript: ENSMUST00000169105
AA Change: C1440S

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000132149
Gene: ENSMUSG00000000631
AA Change: C1440S

DomainStartEndE-ValueType
low complexity region 6 27 N/A INTRINSIC
low complexity region 202 227 N/A INTRINSIC
PDZ 229 311 5.72e-10 SMART
MYSc 411 1194 4.16e-47 SMART
IQ 1195 1217 1.11e-3 SMART
Pfam:Myosin_tail_1 1230 1878 7.3e-35 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000172303
AA Change: C1115S

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000129098
Gene: ENSMUSG00000000631
AA Change: C1115S

DomainStartEndE-ValueType
MYSc 80 863 4.16e-47 SMART
IQ 864 886 1.11e-3 SMART
Pfam:Myosin_tail_1 902 1547 2.6e-34 PFAM
Coding Region Coverage
  • 1x: 100.0%
  • 3x: 100.0%
  • 10x: 99.7%
  • 20x: 99.0%
Validation Efficiency
MGI Phenotype FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene can bind GOLPH3, linking the Golgi to the cytoskeleton and influencing Golgi membrane trafficking. The encoded protein is also part of a complex that assembles lamellar actomyosin bundles and may be required for cell migration. [provided by RefSeq, Oct 2016]
Allele List at MGI
Other mutations in this stock
Total: 76 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca5 A T 11: 110,218,556 (GRCm39) probably null Het
Abcc10 A G 17: 46,623,830 (GRCm39) S810P possibly damaging Het
Adam22 T C 5: 8,132,239 (GRCm39) H138R possibly damaging Het
Adcyap1 T A 17: 93,510,257 (GRCm39) L95* probably null Het
Adgrl4 C A 3: 151,144,887 (GRCm39) T12N probably benign Het
Alpi T C 1: 87,026,677 (GRCm39) N438S probably benign Het
Ankrd44 T C 1: 54,687,483 (GRCm39) N979D probably benign Het
Ankrd60 A C 2: 173,419,966 (GRCm39) S57A probably benign Het
Arfgef3 G A 10: 18,522,377 (GRCm39) P550S probably benign Het
Btbd16 A T 7: 130,422,202 (GRCm39) D390V probably damaging Het
Cacna2d4 T C 6: 119,248,208 (GRCm39) V374A probably benign Het
Cdcp1 A T 9: 123,014,172 (GRCm39) F201I probably benign Het
Cdh15 A T 8: 123,588,865 (GRCm39) D313V probably damaging Het
Cfap157 A G 2: 32,669,890 (GRCm39) L231P possibly damaging Het
Chl1 T G 6: 103,688,162 (GRCm39) C1001G probably damaging Het
Cmtr2 A G 8: 110,948,770 (GRCm39) H360R probably damaging Het
Csmd1 C T 8: 16,261,732 (GRCm39) A922T probably damaging Het
Fancg C T 4: 43,010,116 (GRCm39) probably benign Het
Glt8d2 A T 10: 82,488,403 (GRCm39) S356T unknown Het
Gm19410 T A 8: 36,269,386 (GRCm39) C1074S probably damaging Het
Gm9195 C T 14: 72,711,310 (GRCm39) C376Y possibly damaging Het
Gnai3 G A 3: 108,025,693 (GRCm39) R129C Het
Golph3 T G 15: 12,343,404 (GRCm39) probably null Het
H2bc18 T A 3: 96,177,186 (GRCm39) V40D possibly damaging Het
Hk1 C A 10: 62,140,561 (GRCm39) V105F probably damaging Het
Hoxd8 A G 2: 74,536,001 (GRCm39) Y37C probably damaging Het
Inava T A 1: 136,142,122 (GRCm39) D659V possibly damaging Het
Jun G T 4: 94,939,234 (GRCm39) P92Q probably damaging Het
Klhl14 C T 18: 21,784,597 (GRCm39) V277I probably damaging Het
Lrrc51 C T 7: 101,569,843 (GRCm39) probably null Het
Man2c1 T A 9: 57,045,100 (GRCm39) Y429* probably null Het
Neb G C 2: 52,066,635 (GRCm39) T6155R probably damaging Het
Niban3 C G 8: 72,059,342 (GRCm39) C568W probably damaging Het
Nuf2 T C 1: 169,326,422 (GRCm39) E443G possibly damaging Het
Or10j5 C T 1: 172,784,511 (GRCm39) H50Y probably benign Het
Or4c15 A G 2: 88,760,434 (GRCm39) V75A probably benign Het
Or5d37 A T 2: 87,923,954 (GRCm39) C109S probably damaging Het
Or7g32 A G 9: 19,408,685 (GRCm39) I214V probably damaging Het
Osmr A G 15: 6,856,603 (GRCm39) S515P probably damaging Het
Pik3r5 T C 11: 68,367,177 (GRCm39) L84P probably damaging Het
Plcl1 T C 1: 55,736,273 (GRCm39) I538T probably damaging Het
Plxnb1 G T 9: 108,929,929 (GRCm39) V262L probably damaging Het
Pprc1 T C 19: 46,057,804 (GRCm39) S1320P unknown Het
Pramel47 A G 5: 95,490,409 (GRCm39) D347G probably benign Het
Prap1 G A 7: 139,676,120 (GRCm39) probably null Het
Psg23 A T 7: 18,348,699 (GRCm39) V36D probably damaging Het
Ptgr1 A G 4: 58,982,887 (GRCm39) Y49H probably damaging Het
Ptprr A G 10: 116,087,104 (GRCm39) T528A probably benign Het
Rapgef6 T C 11: 54,525,787 (GRCm39) S541P unknown Het
Rnf17 A T 14: 56,753,895 (GRCm39) D1534V probably damaging Het
Sdk1 T G 5: 141,778,731 (GRCm39) S236R possibly damaging Het
Sepsecs A G 5: 52,801,393 (GRCm39) M423T possibly damaging Het
Serpina1f T G 12: 103,658,167 (GRCm39) Y246S probably benign Het
Sftpb T A 6: 72,282,048 (GRCm39) V46E possibly damaging Het
Slc4a1ap G A 5: 31,691,475 (GRCm39) V424I probably benign Het
Slc5a4b G A 10: 75,946,742 (GRCm39) T10M probably benign Het
Slc6a16 T C 7: 44,922,063 (GRCm39) W664R probably damaging Het
Snx8 T C 5: 140,341,827 (GRCm39) E138G probably benign Het
Sox6 T C 7: 115,376,408 (GRCm39) E108G probably benign Het
Sptan1 A T 2: 29,870,209 (GRCm39) I120F probably damaging Het
Sptbn4 T C 7: 27,075,015 (GRCm39) E1452G possibly damaging Het
Stac2 T A 11: 97,930,452 (GRCm39) E372V probably damaging Het
Taco1 A T 11: 105,962,795 (GRCm39) I161F probably damaging Het
Taf1d C A 9: 15,220,133 (GRCm39) D127E possibly damaging Het
Tenm2 T A 11: 36,097,803 (GRCm39) N482Y probably damaging Het
Tenm3 A G 8: 48,729,635 (GRCm39) V1457A possibly damaging Het
Tmem200c A T 17: 69,148,671 (GRCm39) H418L probably benign Het
Tmem81 T C 1: 132,435,884 (GRCm39) V230A probably benign Het
Tnn C T 1: 159,946,074 (GRCm39) V915I possibly damaging Het
Trav8d-2 A T 14: 53,280,154 (GRCm39) Y48F possibly damaging Het
Trpm2 T C 10: 77,801,894 (GRCm39) N57S probably benign Het
Ttn G A 2: 76,598,383 (GRCm39) T19510M probably damaging Het
Ubl7 T C 9: 57,820,167 (GRCm39) L73P unknown Het
Uso1 A G 5: 92,347,734 (GRCm39) D845G possibly damaging Het
Utrn G T 10: 12,277,126 (GRCm39) P3397Q possibly damaging Het
Vmn2r60 AG A 7: 41,845,158 (GRCm39) probably null Het
Other mutations in Myo18a
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00089:Myo18a APN 11 77,738,764 (GRCm39) missense probably damaging 1.00
IGL00753:Myo18a APN 11 77,715,977 (GRCm39) missense probably damaging 1.00
IGL01137:Myo18a APN 11 77,718,655 (GRCm39) missense probably damaging 1.00
IGL01536:Myo18a APN 11 77,711,677 (GRCm39) missense probably damaging 1.00
IGL01642:Myo18a APN 11 77,755,558 (GRCm39) missense probably benign 0.07
IGL01728:Myo18a APN 11 77,668,682 (GRCm39) missense probably damaging 0.99
IGL01780:Myo18a APN 11 77,741,073 (GRCm39) missense probably benign 0.02
IGL02286:Myo18a APN 11 77,668,811 (GRCm39) nonsense probably null
IGL02350:Myo18a APN 11 77,741,073 (GRCm39) missense probably benign 0.02
IGL02357:Myo18a APN 11 77,741,073 (GRCm39) missense probably benign 0.02
IGL02420:Myo18a APN 11 77,709,519 (GRCm39) missense possibly damaging 0.81
IGL02643:Myo18a APN 11 77,668,998 (GRCm39) missense possibly damaging 0.67
IGL02667:Myo18a APN 11 77,748,678 (GRCm39) splice site probably benign
IGL02869:Myo18a APN 11 77,720,699 (GRCm39) splice site probably benign
IGL02869:Myo18a APN 11 77,755,612 (GRCm39) missense probably damaging 1.00
IGL02962:Myo18a APN 11 77,669,061 (GRCm39) missense probably damaging 1.00
IGL02963:Myo18a APN 11 77,732,844 (GRCm39) splice site probably benign
IGL03410:Myo18a APN 11 77,738,830 (GRCm39) missense probably damaging 0.99
IGL03050:Myo18a UTSW 11 77,709,596 (GRCm39) missense probably benign 0.00
R0022:Myo18a UTSW 11 77,734,059 (GRCm39) critical splice donor site probably null
R0064:Myo18a UTSW 11 77,738,170 (GRCm39) missense probably damaging 1.00
R0064:Myo18a UTSW 11 77,738,170 (GRCm39) missense probably damaging 1.00
R0098:Myo18a UTSW 11 77,736,591 (GRCm39) missense probably damaging 1.00
R0322:Myo18a UTSW 11 77,720,626 (GRCm39) missense probably damaging 1.00
R0373:Myo18a UTSW 11 77,711,868 (GRCm39) missense probably benign 0.01
R0379:Myo18a UTSW 11 77,741,632 (GRCm39) missense possibly damaging 0.84
R0513:Myo18a UTSW 11 77,702,420 (GRCm39) intron probably benign
R0688:Myo18a UTSW 11 77,714,966 (GRCm39) missense probably damaging 1.00
R0734:Myo18a UTSW 11 77,738,230 (GRCm39) missense probably damaging 1.00
R0790:Myo18a UTSW 11 77,731,535 (GRCm39) missense possibly damaging 0.95
R1099:Myo18a UTSW 11 77,709,727 (GRCm39) splice site probably null
R1103:Myo18a UTSW 11 77,714,156 (GRCm39) missense probably damaging 1.00
R1183:Myo18a UTSW 11 77,748,571 (GRCm39) missense probably damaging 1.00
R1216:Myo18a UTSW 11 77,709,473 (GRCm39) missense probably benign 0.35
R1331:Myo18a UTSW 11 77,732,405 (GRCm39) missense probably benign 0.28
R1479:Myo18a UTSW 11 77,733,020 (GRCm39) missense probably benign 0.04
R1723:Myo18a UTSW 11 77,744,140 (GRCm39) missense probably damaging 0.97
R1742:Myo18a UTSW 11 77,732,293 (GRCm39) missense probably damaging 0.99
R1796:Myo18a UTSW 11 77,720,170 (GRCm39) missense possibly damaging 0.94
R1823:Myo18a UTSW 11 77,715,923 (GRCm39) splice site probably benign
R1827:Myo18a UTSW 11 77,709,597 (GRCm39) missense probably benign 0.00
R2033:Myo18a UTSW 11 77,733,925 (GRCm39) splice site probably null
R2043:Myo18a UTSW 11 77,714,189 (GRCm39) missense probably damaging 0.99
R2105:Myo18a UTSW 11 77,741,060 (GRCm39) missense probably benign
R2191:Myo18a UTSW 11 77,709,441 (GRCm39) missense probably damaging 0.99
R2264:Myo18a UTSW 11 77,710,798 (GRCm39) splice site probably benign
R2370:Myo18a UTSW 11 77,668,596 (GRCm39) missense probably benign 0.03
R3015:Myo18a UTSW 11 77,749,846 (GRCm39) intron probably benign
R3433:Myo18a UTSW 11 77,708,870 (GRCm39) splice site probably null
R3739:Myo18a UTSW 11 77,736,441 (GRCm39) missense probably damaging 1.00
R3825:Myo18a UTSW 11 77,668,292 (GRCm39) missense possibly damaging 0.47
R4056:Myo18a UTSW 11 77,702,839 (GRCm39) missense possibly damaging 0.72
R4163:Myo18a UTSW 11 77,720,534 (GRCm39) missense possibly damaging 0.72
R4184:Myo18a UTSW 11 77,748,613 (GRCm39) missense probably damaging 1.00
R4620:Myo18a UTSW 11 77,708,773 (GRCm39) missense possibly damaging 0.93
R4628:Myo18a UTSW 11 77,714,962 (GRCm39) missense probably damaging 1.00
R4647:Myo18a UTSW 11 77,708,776 (GRCm39) missense probably damaging 1.00
R4701:Myo18a UTSW 11 77,708,491 (GRCm39) missense probably damaging 1.00
R4729:Myo18a UTSW 11 77,668,511 (GRCm39) splice site probably null
R4731:Myo18a UTSW 11 77,720,585 (GRCm39) missense probably benign 0.00
R4739:Myo18a UTSW 11 77,714,149 (GRCm39) missense probably damaging 1.00
R4814:Myo18a UTSW 11 77,750,062 (GRCm39) intron probably benign
R4889:Myo18a UTSW 11 77,723,238 (GRCm39) missense probably damaging 1.00
R4988:Myo18a UTSW 11 77,736,347 (GRCm39) critical splice donor site probably null
R5172:Myo18a UTSW 11 77,714,924 (GRCm39) missense probably damaging 1.00
R5177:Myo18a UTSW 11 77,755,668 (GRCm39) utr 3 prime probably benign
R5394:Myo18a UTSW 11 77,744,176 (GRCm39) missense probably benign 0.14
R5643:Myo18a UTSW 11 77,745,513 (GRCm39) missense probably benign 0.12
R5808:Myo18a UTSW 11 77,720,127 (GRCm39) missense probably benign 0.34
R5871:Myo18a UTSW 11 77,723,306 (GRCm39) missense probably damaging 1.00
R5936:Myo18a UTSW 11 77,709,039 (GRCm39) missense probably damaging 1.00
R6017:Myo18a UTSW 11 77,732,349 (GRCm39) missense probably damaging 0.96
R6053:Myo18a UTSW 11 77,709,002 (GRCm39) missense probably damaging 1.00
R6271:Myo18a UTSW 11 77,711,635 (GRCm39) missense probably damaging 1.00
R6486:Myo18a UTSW 11 77,755,648 (GRCm39) missense possibly damaging 0.83
R6558:Myo18a UTSW 11 77,741,678 (GRCm39) missense probably damaging 0.99
R6884:Myo18a UTSW 11 77,709,875 (GRCm39) missense possibly damaging 0.67
R6983:Myo18a UTSW 11 77,736,341 (GRCm39) missense probably benign 0.06
R6993:Myo18a UTSW 11 77,749,900 (GRCm39) intron probably benign
R7071:Myo18a UTSW 11 77,714,653 (GRCm39) missense probably damaging 1.00
R7074:Myo18a UTSW 11 77,733,387 (GRCm39) missense probably benign 0.03
R7238:Myo18a UTSW 11 77,733,059 (GRCm39) missense probably damaging 0.96
R7328:Myo18a UTSW 11 77,698,737 (GRCm39) missense
R7598:Myo18a UTSW 11 77,738,172 (GRCm39) missense probably damaging 1.00
R7671:Myo18a UTSW 11 77,750,246 (GRCm39) missense
R7958:Myo18a UTSW 11 77,732,383 (GRCm39) missense probably damaging 1.00
R8098:Myo18a UTSW 11 77,736,227 (GRCm39) missense probably damaging 0.97
R8168:Myo18a UTSW 11 77,711,968 (GRCm39) missense probably damaging 0.99
R8318:Myo18a UTSW 11 77,714,215 (GRCm39) missense probably benign 0.02
R8685:Myo18a UTSW 11 77,745,520 (GRCm39) missense probably benign 0.00
R8778:Myo18a UTSW 11 77,714,150 (GRCm39) missense probably damaging 1.00
R9023:Myo18a UTSW 11 77,718,477 (GRCm39) missense probably damaging 1.00
R9059:Myo18a UTSW 11 77,668,899 (GRCm39) missense possibly damaging 0.78
R9186:Myo18a UTSW 11 77,749,847 (GRCm39) missense
R9321:Myo18a UTSW 11 77,733,370 (GRCm39) missense probably damaging 0.97
R9357:Myo18a UTSW 11 77,733,014 (GRCm39) missense probably damaging 1.00
R9407:Myo18a UTSW 11 77,709,596 (GRCm39) missense probably benign 0.00
R9430:Myo18a UTSW 11 77,709,410 (GRCm39) missense possibly damaging 0.64
R9576:Myo18a UTSW 11 77,709,827 (GRCm39) missense probably damaging 1.00
R9585:Myo18a UTSW 11 77,709,495 (GRCm39) missense probably benign 0.06
R9698:Myo18a UTSW 11 77,720,681 (GRCm39) missense probably damaging 0.99
R9743:Myo18a UTSW 11 77,723,304 (GRCm39) missense probably benign 0.10
R9777:Myo18a UTSW 11 77,733,080 (GRCm39) missense possibly damaging 0.94
Y5407:Myo18a UTSW 11 77,668,641 (GRCm39) missense probably benign 0.44
Z1177:Myo18a UTSW 11 77,732,821 (GRCm39) missense probably damaging 1.00
Z1187:Myo18a UTSW 11 77,744,643 (GRCm39) missense possibly damaging 0.95
Predicted Primers PCR Primer
(F):5'- GTATCAAGTCTTGGGTTCCGAAG -3'
(R):5'- AGGAGAGAGCCTGTTTCGTG -3'

Sequencing Primer
(F):5'- TCTTGGGTTCCGAAGATGCCC -3'
(R):5'- TTCGTGTCACAGCATGGC -3'
Posted On 2019-10-17