Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01479:Gm10118'

88545

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm10118

Ensembl Gene

ENSMUSG00000062561

Gene Name

predicted gene 10118

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.097) question?

Stock #

IGL01479

Quality Score

Status

Chromosome

Chromosomal Location

63760645-63763213 bp(-) (GRCm39)

Type of Mutation

intron

DNA Base Change (assembly)

T to C at 63762599 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000101081 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000075099] [ENSMUST00000079279] [ENSMUST00000105439] [ENSMUST00000105440] [ENSMUST00000105441]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000075099

SMART Domains

Protein: ENSMUSP00000074606
Gene: ENSMUSG00000060843

Domain	Start	End	E-Value	Type
Pfam:Vinculin	17	363	5.1e-66	PFAM
Pfam:Vinculin	324	856	1e-175	PFAM

Predicted Effect

unknown
Transcript: ENSMUST00000079279
AA Change: D113G

Predicted Effect

probably benign
Transcript: ENSMUST00000105439

SMART Domains

Protein: ENSMUSP00000101079
Gene: ENSMUSG00000042846

Domain	Start	End	E-Value	Type
low complexity region	13	27	N/A	INTRINSIC
LRRNT	33	65	2.11e-3	SMART
LRR_TYP	84	107	2.09e-3	SMART
LRR	108	131	6.77e0	SMART
LRR_TYP	132	155	2.71e-2	SMART
LRR_TYP	156	179	1.47e-3	SMART
LRR	180	203	1.43e-1	SMART
LRR	204	227	1.29e1	SMART
LRR	228	251	2.14e1	SMART
LRR	252	276	1.45e1	SMART
LRR	277	300	2.02e-1	SMART
Blast:LRRCT	312	361	6e-16	BLAST
transmembrane domain	421	443	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000105440

SMART Domains

Protein: ENSMUSP00000101080
Gene: ENSMUSG00000060843

Domain	Start	End	E-Value	Type
Pfam:Vinculin	17	363	5.1e-66	PFAM
Pfam:Vinculin	324	856	1e-175	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000105441

SMART Domains

Protein: ENSMUSP00000101081
Gene: ENSMUSG00000060843

Domain	Start	End	E-Value	Type
Pfam:Vinculin	17	363	5.1e-66	PFAM
Pfam:Vinculin	324	856	1e-175	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000131945

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000135474

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 28 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Akr1c12	T	C	13: 4,322,934 (GRCm39)	K225R	probably benign	Het
Amn	C	A	12: 111,238,227 (GRCm39)	A47E	probably damaging	Het
Arhgef1	T	C	7: 24,612,028 (GRCm39)	I137T	probably benign	Het
Cep57l1	T	C	10: 41,604,635 (GRCm39)	K165E	possibly damaging	Het
Chfr	A	G	5: 110,292,859 (GRCm39)		probably benign	Het
Dnah9	A	G	11: 65,846,543 (GRCm39)	V2923A	probably benign	Het
Dnaja2	T	C	8: 86,280,580 (GRCm39)	Y35C	probably damaging	Het
Dnajc2	T	C	5: 21,962,891 (GRCm39)	T481A	probably damaging	Het
Foxred2	A	G	15: 77,836,489 (GRCm39)		probably null	Het
Gin1	C	T	1: 97,720,097 (GRCm39)	T364I	possibly damaging	Het
Glt8d2	C	T	10: 82,496,570 (GRCm39)	V163I	probably damaging	Het
Hps5	C	T	7: 46,412,366 (GRCm39)		probably null	Het
Kdm4c	A	G	4: 74,261,738 (GRCm39)	K638E	probably benign	Het
L3mbtl2	A	G	15: 81,560,593 (GRCm39)	T285A	probably benign	Het
Mab21l1	A	G	3: 55,691,253 (GRCm39)	Y280C	probably damaging	Het
Mcoln2	T	A	3: 145,881,407 (GRCm39)		probably benign	Het
Myo9b	G	T	8: 71,811,986 (GRCm39)	R1926L	probably damaging	Het
Rrp12	A	G	19: 41,853,641 (GRCm39)	V1251A	probably benign	Het
Rtn4rl1	A	G	11: 75,156,168 (GRCm39)	D200G	probably damaging	Het
Sbsn	G	A	7: 30,451,782 (GRCm39)	A266T	possibly damaging	Het
Sgca	A	T	11: 94,854,204 (GRCm39)	C335*	probably null	Het
Spag1	T	C	15: 36,233,345 (GRCm39)		probably benign	Het
Sult6b1	A	T	17: 79,213,005 (GRCm39)	V82D	probably benign	Het
Tigit	T	C	16: 43,479,885 (GRCm39)	T137A	probably benign	Het
Tmem125	G	A	4: 118,398,820 (GRCm39)	Q204*	probably null	Het
Tmem59l	C	T	8: 70,938,748 (GRCm39)	R111Q	probably benign	Het
Vmn2r95	G	A	17: 18,664,124 (GRCm39)	G448R	probably damaging	Het
Zfp64	T	C	2: 168,793,599 (GRCm39)	H49R	probably damaging	Het

Other mutations in Gm10118

Allele	Source	Chr	Coord	Type	Predicted Effect
R0839:Gm10118	UTSW	10	63,762,643 (GRCm39)	intron	probably benign
R1699:Gm10118	UTSW	10	63,762,671 (GRCm39)	intron	probably benign
R5590:Gm10118	UTSW	10	63,762,845 (GRCm39)	intron	probably benign
R5889:Gm10118	UTSW	10	63,762,890 (GRCm39)	intron	probably benign
R8681:Gm10118	UTSW	10	63,762,756 (GRCm39)	missense	unknown

Posted On

2013-11-18