Incidental Mutation 'IGL01626:Olfr709-ps1'
ID92765
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Olfr709-ps1
Ensembl Gene ENSMUSG00000062553
Gene Nameolfactory receptor 709, pseudogene 1
SynonymsGA_x6K02T2PBJ9-9307730-9306814, MOR260-7
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.122) question?
Stock #IGL01626
Quality Score
Status
Chromosome7
Chromosomal Location106922874-106932219 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 106927420 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Asparagine at position 13 (I13N)
Ref Sequence ENSEMBL: ENSMUSP00000150392 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000072368] [ENSMUST00000215468]
Predicted Effect probably benign
Transcript: ENSMUST00000072368
AA Change: I13N

PolyPhen 2 Score 0.120 (Sensitivity: 0.93; Specificity: 0.86)
SMART Domains Protein: ENSMUSP00000072205
Gene: ENSMUSG00000062553
AA Change: I13N

DomainStartEndE-ValueType
Pfam:7tm_4 31 307 7.8e-58 PFAM
Pfam:7TM_GPCR_Srsx 35 282 8.4e-9 PFAM
Pfam:7tm_1 41 290 5.9e-27 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000215468
AA Change: I13N

PolyPhen 2 Score 0.120 (Sensitivity: 0.93; Specificity: 0.86)
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 48 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aadacl2 A G 3: 60,019,174 D188G probably damaging Het
AI314180 G A 4: 58,832,814 probably benign Het
Aoc1 A G 6: 48,906,531 Y447C probably damaging Het
Brd1 A T 15: 88,700,887 L915M probably damaging Het
Cacna2d3 T A 14: 28,943,607 E152D possibly damaging Het
Dnase2b A G 3: 146,584,616 probably null Het
Fat4 T C 3: 38,951,032 V1860A probably damaging Het
Fbxl5 C A 5: 43,758,705 G455V probably benign Het
Fpr-rs4 G A 17: 18,022,231 V167M probably damaging Het
Fut7 C A 2: 25,425,331 Y153* probably null Het
Gnptab A G 10: 88,437,495 T1045A probably damaging Het
Gucy1a1 T A 3: 82,108,619 D354V probably damaging Het
Gucy2e A G 11: 69,232,855 V406A possibly damaging Het
Herc2 T C 7: 56,085,142 F160S probably benign Het
Ice2 T G 9: 69,407,332 V42G probably benign Het
L3mbtl4 A G 17: 68,630,202 Y406C probably damaging Het
Lepr C T 4: 101,733,534 T103I probably benign Het
Ly75 T A 2: 60,301,015 M1589L probably benign Het
Map4k3 A G 17: 80,605,809 V644A probably damaging Het
Micall1 A G 15: 79,130,512 D696G possibly damaging Het
Muc4 T C 16: 32,736,402 V8A possibly damaging Het
Myo1h A G 5: 114,314,966 D9G probably damaging Het
Nop14 T A 5: 34,649,345 K472* probably null Het
Npat T A 9: 53,556,571 D275E possibly damaging Het
Nt5c1b A G 12: 10,374,798 T115A probably benign Het
Olfr429 A G 1: 174,089,556 N172S probably damaging Het
Pnpla7 T A 2: 25,050,893 S1086T possibly damaging Het
Pold1 C T 7: 44,533,372 probably null Het
Ppfia1 A G 7: 144,481,719 F1165L probably benign Het
Prlr T A 15: 10,328,718 D426E probably benign Het
Ptgs2 G A 1: 150,103,727 R231H probably damaging Het
Rorc A G 3: 94,388,787 D91G probably damaging Het
Scaper C T 9: 55,912,051 V127M possibly damaging Het
Sema3g A T 14: 31,221,727 Y188F probably damaging Het
Slc45a3 G T 1: 131,978,987 A400S possibly damaging Het
Slc9b2 C A 3: 135,336,395 H478Q probably benign Het
Spg11 T A 2: 122,060,971 H1973L probably damaging Het
Srgap3 A G 6: 112,773,648 Y359H probably damaging Het
Stx16 T G 2: 174,094,020 I248S probably damaging Het
Sytl3 A G 17: 6,735,440 R287G probably damaging Het
Tiam1 T C 16: 89,812,968 T82A probably damaging Het
Trpm1 T C 7: 64,268,889 L659P probably damaging Het
Ttc13 G A 8: 124,673,738 probably benign Het
Unc80 T C 1: 66,551,054 probably null Het
Vldlr G T 19: 27,243,773 R613L probably damaging Het
Wdr77 C T 3: 105,959,686 R35* probably null Het
Zc3h14 T G 12: 98,779,186 I478R possibly damaging Het
Zfp366 A G 13: 99,228,412 H27R probably damaging Het
Other mutations in Olfr709-ps1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02111:Olfr709-ps1 APN 7 106926616 missense probably damaging 0.99
IGL02891:Olfr709-ps1 APN 7 106927081 missense probably damaging 0.99
PIT4453001:Olfr709-ps1 UTSW 7 106926842 missense probably benign 0.07
R1553:Olfr709-ps1 UTSW 7 106926994 missense possibly damaging 0.78
R1701:Olfr709-ps1 UTSW 7 106926922 missense probably damaging 1.00
R2065:Olfr709-ps1 UTSW 7 106926955 missense probably damaging 1.00
R2068:Olfr709-ps1 UTSW 7 106926955 missense probably damaging 1.00
R2167:Olfr709-ps1 UTSW 7 106926590 missense probably damaging 1.00
R3683:Olfr709-ps1 UTSW 7 106927094 nonsense probably null
R4640:Olfr709-ps1 UTSW 7 106926593 missense possibly damaging 0.73
R5153:Olfr709-ps1 UTSW 7 106926569 missense possibly damaging 0.91
R5221:Olfr709-ps1 UTSW 7 106927061 missense probably benign 0.00
R5591:Olfr709-ps1 UTSW 7 106927282 missense probably damaging 1.00
R6052:Olfr709-ps1 UTSW 7 106926689 missense probably benign 0.05
R7358:Olfr709-ps1 UTSW 7 106926904 missense probably damaging 1.00
Posted On2013-12-09