Incidental Mutation 'IGL01889:Olfr1336'
ID179216
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Olfr1336
Ensembl Gene ENSMUSG00000048620
Gene Nameolfactory receptor 1336
SynonymsGA_x6K02T2QGBW-3190370-3191314, MOR103-7
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.090) question?
Stock #IGL01889
Quality Score
Status
Chromosome7
Chromosomal Location6456168-6466817 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) G to A at 6460503 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000150162 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000056120] [ENSMUST00000214301]
Predicted Effect probably benign
Transcript: ENSMUST00000056120
SMART Domains Protein: ENSMUSP00000056956
Gene: ENSMUSG00000048620

DomainStartEndE-ValueType
Pfam:7tm_4 35 311 3.2e-52 PFAM
Pfam:7tm_1 45 294 2.2e-18 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000214301
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Allele List at MGI
Other mutations in this stock
Total: 21 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
A730049H05Rik G A 6: 92,828,000 probably benign Het
Brap G A 5: 121,660,818 V18I probably benign Het
Csmd1 C T 8: 15,998,857 V2282M probably damaging Het
Flnb A G 14: 7,935,967 E2269G possibly damaging Het
Gaa A G 11: 119,278,297 I557V probably benign Het
Gapt T A 13: 110,353,967 Q54L probably benign Het
Gsdmc A T 15: 63,780,003 I253N possibly damaging Het
Kcnj3 T A 2: 55,437,204 S2T possibly damaging Het
Mindy2 T C 9: 70,631,162 probably benign Het
Ncor1 A G 11: 62,334,601 V1048A possibly damaging Het
Nlrp4d A T 7: 10,378,334 V636D unknown Het
Nphs1 G T 7: 30,460,511 R82S probably damaging Het
Olfr1269 A G 2: 90,118,965 V211A possibly damaging Het
Olfr512 T A 7: 108,713,882 F164L probably benign Het
Papln T A 12: 83,786,835 L1175Q probably benign Het
Rab22a T C 2: 173,688,238 probably benign Het
Rel A G 11: 23,757,035 Y56H probably damaging Het
Sdc4 A G 2: 164,431,207 L61P probably damaging Het
Slc1a4 A G 11: 20,314,089 probably benign Het
Ubr4 T A 4: 139,462,472 C3989* probably null Het
Zfyve16 A G 13: 92,522,569 V278A possibly damaging Het
Other mutations in Olfr1336
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02730:Olfr1336 APN 7 6461124 missense possibly damaging 0.75
R1193:Olfr1336 UTSW 7 6460716 missense probably benign 0.14
R1582:Olfr1336 UTSW 7 6460814 missense probably benign 0.02
R1616:Olfr1336 UTSW 7 6460745 missense probably damaging 1.00
R1954:Olfr1336 UTSW 7 6461145 missense probably benign 0.11
R2889:Olfr1336 UTSW 7 6460941 missense probably damaging 1.00
R4881:Olfr1336 UTSW 7 6460754 missense probably benign 0.01
R4958:Olfr1336 UTSW 7 6461058 missense probably damaging 1.00
R5849:Olfr1336 UTSW 7 6460994 missense possibly damaging 0.46
R6253:Olfr1336 UTSW 7 6460548 missense probably benign 0.09
R7289:Olfr1336 UTSW 7 6460778 missense probably benign 0.00
Z1177:Olfr1336 UTSW 7 6461227 missense probably benign 0.12
Posted On2014-05-07