Incidental Mutation 'IGL02036:Pcyox1l'
ID184531
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Pcyox1l
Ensembl Gene ENSMUSG00000024579
Gene Nameprenylcysteine oxidase 1 like
Synonyms
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL02036
Quality Score
Status
Chromosome18
Chromosomal Location61696837-61707635 bp(-) (GRCm38)
Type of Mutationunclassified
DNA Base Change (assembly) T to C at 61707536 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000053440 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000025472] [ENSMUST00000062991] [ENSMUST00000195229]
Predicted Effect unknown
Transcript: ENSMUST00000025472
AA Change: T16A
SMART Domains Protein: ENSMUSP00000025472
Gene: ENSMUSG00000024579
AA Change: T16A

DomainStartEndE-ValueType
signal peptide 1 20 N/A INTRINSIC
Pfam:NAD_binding_8 31 98 2.8e-12 PFAM
Pfam:Amino_oxidase 36 380 3.5e-11 PFAM
Pfam:Prenylcys_lyase 120 491 1.3e-145 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000062991
SMART Domains Protein: ENSMUSP00000053440
Gene: ENSMUSG00000024580

DomainStartEndE-ValueType
Pfam:GrpE 44 218 1.8e-42 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000154763
Predicted Effect unknown
Transcript: ENSMUST00000195229
AA Change: T16A
SMART Domains Protein: ENSMUSP00000142249
Gene: ENSMUSG00000024579
AA Change: T16A

DomainStartEndE-ValueType
signal peptide 1 20 N/A INTRINSIC
Pfam:DAO 28 108 2.7e-6 PFAM
Pfam:NAD_binding_8 31 99 2e-11 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
9530053A07Rik G A 7: 28,137,525 V290M possibly damaging Het
Cep290 T A 10: 100,558,100 C2056* probably null Het
Cyp2c38 T A 19: 39,460,316 D143V probably null Het
Ddx10 T C 9: 53,204,183 K617R probably benign Het
Dgat2l6 T A X: 100,545,593 I336N probably damaging Het
Dopey1 A G 9: 86,531,765 I1906M probably benign Het
Dpep3 T G 8: 105,973,785 T430P probably benign Het
Dph1 T C 11: 75,184,165 probably null Het
Epha7 T C 4: 28,950,509 S775P probably damaging Het
F5 A G 1: 164,183,002 probably benign Het
Hdx T A X: 111,659,867 T342S probably benign Het
Inpp4a T C 1: 37,377,569 probably benign Het
Itgad A G 7: 128,189,821 T515A possibly damaging Het
Kcnc2 T A 10: 112,455,926 S340T possibly damaging Het
Krba1 C T 6: 48,415,642 T830I possibly damaging Het
Lrch1 G A 14: 74,795,293 probably benign Het
Mag C T 7: 30,908,452 V295M probably damaging Het
Mmp16 T A 4: 18,093,371 D375E probably benign Het
Olfr1216 A G 2: 89,013,479 V195A probably benign Het
Olfr314 T C 11: 58,787,097 Y288H probably damaging Het
Olfr90 A G 17: 37,085,667 F166S probably damaging Het
Secisbp2l A G 2: 125,758,207 S403P probably benign Het
Sh3tc2 T A 18: 62,014,907 H1229Q probably benign Het
Svep1 A C 4: 58,088,245 W1735G possibly damaging Het
Tbxas1 T A 6: 39,021,157 C220S probably benign Het
Vmn1r173 G T 7: 23,702,896 M185I probably benign Het
Ywhag A G 5: 135,911,494 V82A probably benign Het
Other mutations in Pcyox1l
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00434:Pcyox1l APN 18 61697542 missense probably benign 0.01
IGL02478:Pcyox1l APN 18 61697709 missense probably benign 0.34
R0036:Pcyox1l UTSW 18 61697421 missense probably benign 0.13
R0325:Pcyox1l UTSW 18 61697893 missense possibly damaging 0.90
R1726:Pcyox1l UTSW 18 61697778 missense probably benign 0.38
R4457:Pcyox1l UTSW 18 61697868 missense probably benign 0.01
R4763:Pcyox1l UTSW 18 61697779 missense probably benign 0.38
R4811:Pcyox1l UTSW 18 61697535 missense possibly damaging 0.67
R4876:Pcyox1l UTSW 18 61699494 missense probably damaging 0.96
R4983:Pcyox1l UTSW 18 61699397 missense probably damaging 0.98
R5390:Pcyox1l UTSW 18 61699362 missense probably benign 0.19
R5813:Pcyox1l UTSW 18 61699288 splice site probably null
R5933:Pcyox1l UTSW 18 61698473 missense probably benign 0.05
R7018:Pcyox1l UTSW 18 61707554 unclassified probably benign
R7356:Pcyox1l UTSW 18 61707550 missense probably null
R7384:Pcyox1l UTSW 18 61698390 missense probably damaging 1.00
R7393:Pcyox1l UTSW 18 61697641 missense probably benign 0.43
R8125:Pcyox1l UTSW 18 61707505 missense unknown
Posted On2014-05-07