Incidental Mutation 'R1519:Prdm2'
| ID |
167262 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Prdm2
|
| Ensembl Gene |
ENSMUSG00000057637 |
| Gene Name |
PR domain containing 2, with ZNF domain |
| Synonyms |
KMT8, LOC381568, Riz, E330024L24Rik, 4833427P12Rik, Riz1 |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1519 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
142833961-142939560 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 142862153 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Asparagine
at position 379
(I379N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000101404
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000105778]
|
| AlphaFold |
A2A7B5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000105778
AA Change: I379N
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000101404
Gene: ENSMUSG00000057637
AA Change: I379N
| Domain | Start | End | E-Value | Type |
|---|
|
SET
|
29 |
146 |
2.79e-21 |
SMART |
|
coiled coil region
|
254 |
293 |
N/A |
INTRINSIC |
|
low complexity region
|
333 |
346 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
356 |
378 |
2.95e-3 |
SMART |
|
ZnF_C2H2
|
386 |
408 |
4.79e-3 |
SMART |
|
ZnF_C2H2
|
477 |
500 |
4.17e-3 |
SMART |
|
low complexity region
|
517 |
528 |
N/A |
INTRINSIC |
|
low complexity region
|
653 |
669 |
N/A |
INTRINSIC |
|
low complexity region
|
682 |
697 |
N/A |
INTRINSIC |
|
low complexity region
|
726 |
744 |
N/A |
INTRINSIC |
|
low complexity region
|
868 |
877 |
N/A |
INTRINSIC |
|
low complexity region
|
931 |
951 |
N/A |
INTRINSIC |
|
low complexity region
|
954 |
992 |
N/A |
INTRINSIC |
|
low complexity region
|
1011 |
1032 |
N/A |
INTRINSIC |
|
low complexity region
|
1035 |
1080 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1126 |
1148 |
3.52e-1 |
SMART |
|
ZnF_C2H2
|
1154 |
1177 |
7.55e-1 |
SMART |
|
ZnF_C2H2
|
1183 |
1206 |
4.72e-2 |
SMART |
|
low complexity region
|
1239 |
1253 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1324 |
1344 |
5.12e1 |
SMART |
|
low complexity region
|
1406 |
1423 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1446 |
1466 |
1.86e1 |
SMART |
|
low complexity region
|
1475 |
1507 |
N/A |
INTRINSIC |
|
low complexity region
|
1551 |
1568 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000197026
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.4%
- 20x: 92.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
PHENOTYPE: Homozygous null mice have shortened life spans, becoming moribund due to increased incidence of tumors. Mice had a broad spectrum of unusual tumors in multiple organs, with a high incidence of diffuse large B cell lymphomas. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700017N19Rik |
C |
G |
10: 100,439,390 (GRCm39) |
P187R |
probably damaging |
Het |
| Abhd5 |
T |
C |
9: 122,208,079 (GRCm39) |
|
probably null |
Het |
| Acadvl |
A |
G |
11: 69,905,617 (GRCm39) |
|
probably null |
Het |
| Actn1 |
T |
C |
12: 80,251,852 (GRCm39) |
E75G |
probably damaging |
Het |
| Adam4 |
A |
T |
12: 81,467,651 (GRCm39) |
N323K |
possibly damaging |
Het |
| Anks6 |
G |
A |
4: 47,027,152 (GRCm39) |
R689W |
probably damaging |
Het |
| Anxa2 |
T |
C |
9: 69,392,523 (GRCm39) |
I124T |
probably damaging |
Het |
| Aph1c |
T |
C |
9: 66,740,547 (GRCm39) |
T10A |
probably benign |
Het |
| Arhgap40 |
T |
A |
2: 158,388,721 (GRCm39) |
W552R |
probably benign |
Het |
| Baz2b |
C |
T |
2: 59,778,598 (GRCm39) |
R754H |
possibly damaging |
Het |
| Blmh |
A |
G |
11: 76,857,607 (GRCm39) |
Y147C |
probably damaging |
Het |
| C1galt1 |
C |
T |
6: 7,866,402 (GRCm39) |
L83F |
probably damaging |
Het |
| Ccdc168 |
A |
G |
1: 44,096,130 (GRCm39) |
V1656A |
probably benign |
Het |
| Cdh23 |
A |
T |
10: 60,215,122 (GRCm39) |
Y1403N |
possibly damaging |
Het |
| Cic |
A |
T |
7: 24,993,235 (GRCm39) |
|
probably null |
Het |
| Coro1b |
T |
A |
19: 4,200,583 (GRCm39) |
V200D |
possibly damaging |
Het |
| Csl |
T |
A |
10: 99,593,817 (GRCm39) |
E416V |
probably damaging |
Het |
| Cyp3a25 |
A |
G |
5: 145,938,257 (GRCm39) |
|
probably null |
Het |
| Dennd2d |
T |
A |
3: 106,399,875 (GRCm39) |
F266Y |
probably damaging |
Het |
| Dnah10 |
A |
G |
5: 124,838,016 (GRCm39) |
E1072G |
probably damaging |
Het |
| Dnah6 |
T |
A |
6: 73,026,031 (GRCm39) |
K3435N |
probably damaging |
Het |
| Dnah9 |
G |
A |
11: 65,772,587 (GRCm39) |
A3715V |
probably damaging |
Het |
| Fam186a |
G |
A |
15: 99,845,536 (GRCm39) |
S236L |
unknown |
Het |
| Frs3 |
A |
G |
17: 48,013,903 (GRCm39) |
T199A |
probably benign |
Het |
| Fsd1 |
A |
G |
17: 56,300,870 (GRCm39) |
N243S |
probably benign |
Het |
| Gabra5 |
A |
C |
7: 57,058,641 (GRCm39) |
L369R |
probably benign |
Het |
| Gask1b |
A |
G |
3: 79,848,771 (GRCm39) |
N506D |
possibly damaging |
Het |
| Gins4 |
A |
G |
8: 23,724,792 (GRCm39) |
V54A |
probably benign |
Het |
| Gli1 |
T |
C |
10: 127,170,138 (GRCm39) |
E339G |
possibly damaging |
Het |
| Gm12185 |
A |
G |
11: 48,798,594 (GRCm39) |
V633A |
probably damaging |
Het |
| Gpr83 |
T |
A |
9: 14,779,493 (GRCm39) |
C182S |
probably null |
Het |
| Gspt1 |
A |
G |
16: 11,038,719 (GRCm39) |
V627A |
probably damaging |
Het |
| Heatr1 |
T |
C |
13: 12,427,040 (GRCm39) |
C722R |
probably benign |
Het |
| Jak1 |
C |
T |
4: 101,020,119 (GRCm39) |
R680Q |
probably damaging |
Het |
| Kif2c |
A |
G |
4: 117,027,137 (GRCm39) |
V287A |
probably damaging |
Het |
| Kmo |
C |
T |
1: 175,479,184 (GRCm39) |
P240L |
possibly damaging |
Het |
| Kmo |
A |
G |
1: 175,484,368 (GRCm39) |
E366G |
probably damaging |
Het |
| Lepr |
A |
T |
4: 101,646,541 (GRCm39) |
N824I |
probably damaging |
Het |
| Lyrm7 |
T |
A |
11: 54,739,425 (GRCm39) |
H75L |
possibly damaging |
Het |
| Map4k1 |
A |
T |
7: 28,690,461 (GRCm39) |
Q351L |
probably benign |
Het |
| Matcap2 |
T |
G |
9: 22,341,671 (GRCm39) |
L114R |
probably benign |
Het |
| Mgam |
T |
C |
6: 40,638,617 (GRCm39) |
I450T |
probably benign |
Het |
| Nbeal2 |
A |
G |
9: 110,465,373 (GRCm39) |
L955P |
probably damaging |
Het |
| Nlrp9c |
T |
C |
7: 26,077,526 (GRCm39) |
K752R |
possibly damaging |
Het |
| Nsmaf |
A |
T |
4: 6,438,062 (GRCm39) |
I70K |
probably benign |
Het |
| Or14a257 |
A |
G |
7: 86,138,333 (GRCm39) |
M142T |
probably damaging |
Het |
| Or5ac19 |
C |
T |
16: 59,089,307 (GRCm39) |
C241Y |
probably damaging |
Het |
| Otud7a |
A |
G |
7: 63,408,391 (GRCm39) |
Y898C |
probably damaging |
Het |
| Pcdhb18 |
A |
C |
18: 37,623,945 (GRCm39) |
D425A |
probably damaging |
Het |
| Prdm1 |
A |
T |
10: 44,315,982 (GRCm39) |
L733* |
probably null |
Het |
| Ptprg |
A |
T |
14: 12,220,596 (GRCm38) |
Y436F |
probably damaging |
Het |
| Riok3 |
A |
G |
18: 12,270,363 (GRCm39) |
D167G |
probably damaging |
Het |
| Rnf215 |
G |
T |
11: 4,085,451 (GRCm39) |
R60L |
probably damaging |
Het |
| Scart1 |
G |
A |
7: 139,808,069 (GRCm39) |
V747I |
probably benign |
Het |
| Sdk1 |
A |
T |
5: 141,985,705 (GRCm39) |
H779L |
probably benign |
Het |
| Serpine2 |
A |
G |
1: 79,772,748 (GRCm39) |
F390L |
probably damaging |
Het |
| Sh3d21 |
T |
A |
4: 126,045,519 (GRCm39) |
K387* |
probably null |
Het |
| Slc13a2 |
T |
C |
11: 78,288,572 (GRCm39) |
Y568C |
possibly damaging |
Het |
| Slc27a5 |
T |
C |
7: 12,722,386 (GRCm39) |
|
probably null |
Het |
| Slc32a1 |
T |
C |
2: 158,456,497 (GRCm39) |
L384P |
probably damaging |
Het |
| Sorcs1 |
T |
C |
19: 50,241,025 (GRCm39) |
N454D |
probably benign |
Het |
| Spag8 |
T |
C |
4: 43,652,777 (GRCm39) |
Y228C |
possibly damaging |
Het |
| Spata31e4 |
G |
A |
13: 50,854,443 (GRCm39) |
|
probably null |
Het |
| Spc25 |
T |
C |
2: 69,030,431 (GRCm39) |
I71V |
probably damaging |
Het |
| Tcte1 |
T |
A |
17: 45,846,178 (GRCm39) |
F261I |
probably damaging |
Het |
| Thsd7a |
T |
A |
6: 12,471,174 (GRCm39) |
K481N |
probably benign |
Het |
| Tll2 |
G |
T |
19: 41,074,839 (GRCm39) |
N908K |
probably benign |
Het |
| Tmem236 |
T |
C |
2: 14,197,091 (GRCm39) |
V93A |
probably benign |
Het |
| Top2b |
G |
A |
14: 16,408,953 (GRCm38) |
|
probably null |
Het |
| Topaz1 |
G |
A |
9: 122,596,076 (GRCm39) |
S949N |
probably benign |
Het |
| Triobp |
A |
G |
15: 78,857,938 (GRCm39) |
T1180A |
probably benign |
Het |
| Trip11 |
A |
C |
12: 101,852,419 (GRCm39) |
D548E |
probably benign |
Het |
| Trpv2 |
T |
A |
11: 62,480,652 (GRCm39) |
|
probably null |
Het |
| Ulbp3 |
A |
G |
10: 3,075,230 (GRCm39) |
|
noncoding transcript |
Het |
| Vmn1r12 |
T |
A |
6: 57,136,540 (GRCm39) |
H212Q |
probably damaging |
Het |
| Vmn2r112 |
A |
G |
17: 22,837,884 (GRCm39) |
T782A |
possibly damaging |
Het |
| Vmn2r7 |
A |
G |
3: 64,623,876 (GRCm39) |
V239A |
possibly damaging |
Het |
| Vmn2r80 |
T |
A |
10: 79,030,053 (GRCm39) |
N626K |
probably damaging |
Het |
| Vmn2r99 |
A |
G |
17: 19,600,322 (GRCm39) |
S449G |
probably benign |
Het |
| Wfikkn2 |
T |
C |
11: 94,128,933 (GRCm39) |
T403A |
probably benign |
Het |
| Xirp2 |
A |
G |
2: 67,346,023 (GRCm39) |
I2755V |
probably benign |
Het |
| Yjefn3 |
A |
G |
8: 70,341,729 (GRCm39) |
V153A |
probably benign |
Het |
| Zfp677 |
C |
A |
17: 21,617,499 (GRCm39) |
H185Q |
possibly damaging |
Het |
| Zfp947 |
C |
T |
17: 22,365,273 (GRCm39) |
V134I |
probably benign |
Het |
|
| Other mutations in Prdm2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00530:Prdm2
|
APN |
4 |
142,860,329 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00843:Prdm2
|
APN |
4 |
142,860,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01419:Prdm2
|
APN |
4 |
142,860,218 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01662:Prdm2
|
APN |
4 |
142,860,138 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL01892:Prdm2
|
APN |
4 |
142,860,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02104:Prdm2
|
APN |
4 |
142,859,997 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02208:Prdm2
|
APN |
4 |
142,862,313 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02260:Prdm2
|
APN |
4 |
142,861,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02479:Prdm2
|
APN |
4 |
142,861,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02943:Prdm2
|
APN |
4 |
142,858,542 (GRCm39) |
missense |
probably benign |
|
|
IGL02972:Prdm2
|
APN |
4 |
142,858,736 (GRCm39) |
missense |
probably benign |
|
|
IGL03038:Prdm2
|
APN |
4 |
142,860,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03399:Prdm2
|
APN |
4 |
142,861,658 (GRCm39) |
missense |
probably benign |
0.07 |
|
G1patch:Prdm2
|
UTSW |
4 |
142,859,471 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
PIT4677001:Prdm2
|
UTSW |
4 |
142,861,648 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0088:Prdm2
|
UTSW |
4 |
142,861,524 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0153:Prdm2
|
UTSW |
4 |
142,860,338 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0320:Prdm2
|
UTSW |
4 |
142,905,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0384:Prdm2
|
UTSW |
4 |
142,862,258 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0400:Prdm2
|
UTSW |
4 |
142,838,240 (GRCm39) |
missense |
probably benign |
|
|
R0658:Prdm2
|
UTSW |
4 |
142,861,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0850:Prdm2
|
UTSW |
4 |
142,858,773 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1118:Prdm2
|
UTSW |
4 |
142,858,953 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R1355:Prdm2
|
UTSW |
4 |
142,858,533 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1936:Prdm2
|
UTSW |
4 |
142,861,032 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1987:Prdm2
|
UTSW |
4 |
142,859,079 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2006:Prdm2
|
UTSW |
4 |
142,858,447 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2008:Prdm2
|
UTSW |
4 |
142,861,517 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2030:Prdm2
|
UTSW |
4 |
142,859,334 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R2112:Prdm2
|
UTSW |
4 |
142,858,506 (GRCm39) |
missense |
probably benign |
|
|
R2221:Prdm2
|
UTSW |
4 |
142,861,469 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R2223:Prdm2
|
UTSW |
4 |
142,861,469 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R2426:Prdm2
|
UTSW |
4 |
142,838,320 (GRCm39) |
nonsense |
probably null |
|
|
R2430:Prdm2
|
UTSW |
4 |
142,859,733 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2484:Prdm2
|
UTSW |
4 |
142,861,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3735:Prdm2
|
UTSW |
4 |
142,860,929 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3944:Prdm2
|
UTSW |
4 |
142,858,385 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R4209:Prdm2
|
UTSW |
4 |
142,861,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4411:Prdm2
|
UTSW |
4 |
142,860,240 (GRCm39) |
missense |
probably benign |
0.18 |
|
R4647:Prdm2
|
UTSW |
4 |
142,859,525 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4898:Prdm2
|
UTSW |
4 |
142,860,761 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5032:Prdm2
|
UTSW |
4 |
142,905,937 (GRCm39) |
nonsense |
probably null |
|
|
R5181:Prdm2
|
UTSW |
4 |
142,861,536 (GRCm39) |
missense |
probably benign |
0.35 |
|
R5513:Prdm2
|
UTSW |
4 |
142,862,463 (GRCm39) |
small deletion |
probably benign |
|
|
R5539:Prdm2
|
UTSW |
4 |
142,859,264 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5563:Prdm2
|
UTSW |
4 |
142,861,200 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5618:Prdm2
|
UTSW |
4 |
142,860,107 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5900:Prdm2
|
UTSW |
4 |
142,861,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5990:Prdm2
|
UTSW |
4 |
142,896,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6148:Prdm2
|
UTSW |
4 |
142,859,477 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6166:Prdm2
|
UTSW |
4 |
142,861,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6223:Prdm2
|
UTSW |
4 |
142,868,777 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6530:Prdm2
|
UTSW |
4 |
142,860,617 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6631:Prdm2
|
UTSW |
4 |
142,861,454 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6725:Prdm2
|
UTSW |
4 |
142,859,471 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R6847:Prdm2
|
UTSW |
4 |
142,859,520 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7193:Prdm2
|
UTSW |
4 |
142,907,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7238:Prdm2
|
UTSW |
4 |
142,862,391 (GRCm39) |
missense |
probably benign |
0.35 |
|
R7292:Prdm2
|
UTSW |
4 |
142,859,471 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R7417:Prdm2
|
UTSW |
4 |
142,905,869 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7748:Prdm2
|
UTSW |
4 |
142,862,459 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7885:Prdm2
|
UTSW |
4 |
142,861,140 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7936:Prdm2
|
UTSW |
4 |
142,862,434 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7976:Prdm2
|
UTSW |
4 |
142,859,812 (GRCm39) |
nonsense |
probably null |
|
|
R8124:Prdm2
|
UTSW |
4 |
142,861,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8150:Prdm2
|
UTSW |
4 |
142,859,303 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8156:Prdm2
|
UTSW |
4 |
142,861,338 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8178:Prdm2
|
UTSW |
4 |
142,859,018 (GRCm39) |
missense |
probably benign |
0.33 |
|
R8235:Prdm2
|
UTSW |
4 |
142,859,037 (GRCm39) |
nonsense |
probably null |
|
|
R8404:Prdm2
|
UTSW |
4 |
142,861,584 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8498:Prdm2
|
UTSW |
4 |
142,907,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8502:Prdm2
|
UTSW |
4 |
142,861,584 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8688:Prdm2
|
UTSW |
4 |
142,838,310 (GRCm39) |
missense |
probably benign |
|
|
R8732:Prdm2
|
UTSW |
4 |
142,862,580 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8796:Prdm2
|
UTSW |
4 |
142,860,017 (GRCm39) |
missense |
probably benign |
0.33 |
|
R8874:Prdm2
|
UTSW |
4 |
142,859,785 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8887:Prdm2
|
UTSW |
4 |
142,860,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9119:Prdm2
|
UTSW |
4 |
142,858,449 (GRCm39) |
nonsense |
probably null |
|
|
R9139:Prdm2
|
UTSW |
4 |
142,858,752 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9165:Prdm2
|
UTSW |
4 |
142,858,674 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9342:Prdm2
|
UTSW |
4 |
142,861,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9518:Prdm2
|
UTSW |
4 |
142,860,579 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9546:Prdm2
|
UTSW |
4 |
142,861,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9547:Prdm2
|
UTSW |
4 |
142,861,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9680:Prdm2
|
UTSW |
4 |
142,859,079 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9730:Prdm2
|
UTSW |
4 |
142,858,659 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
X0017:Prdm2
|
UTSW |
4 |
142,861,277 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GTGAACTCTACGCTGATGTCGTCTC -3'
(R):5'- CCAACTGAAACTTCTGAAGGCTCCC -3'
Sequencing Primer
(F):5'- ACAGTCTTGCCCAAGTTGAG -3'
(R):5'- CTGAAGGCTCCCCAGGC -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation