Incidental Mutation 'R1601:1110032F04Rik'
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ID176131
Institutional Source Beutler Lab
Gene Symbol 1110032F04Rik
Ensembl Gene ENSMUSG00000046999
Gene NameRIKEN cDNA 1110032F04 gene
Synonyms
MMRRC Submission 039638-MU
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.144) question?
Stock #R1601 (G1)
Quality Score137
Status Not validated
Chromosome3
Chromosomal Location68869586-68872163 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to A at 68870213 bp
ZygosityHeterozygous
Amino Acid Change Serine to Asparagine at position 169 (S169N)
Ref Sequence ENSEMBL: ENSMUSP00000056782 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000054551]
Predicted Effect probably benign
Transcript: ENSMUST00000054551
AA Change: S169N

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000056782
Gene: ENSMUSG00000046999
AA Change: S169N

DomainStartEndE-ValueType
signal peptide 1 37 N/A INTRINSIC
Pfam:DUF4719 46 247 6.4e-119 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000166328
SMART Domains Protein: ENSMUSP00000131783
Gene: ENSMUSG00000091272

DomainStartEndE-ValueType
low complexity region 41 59 N/A INTRINSIC
low complexity region 61 82 N/A INTRINSIC
low complexity region 110 136 N/A INTRINSIC
low complexity region 138 149 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000215570
Meta Mutation Damage Score 0.1348 question?
Coding Region Coverage
  • 1x: 98.9%
  • 3x: 98.0%
  • 10x: 95.1%
  • 20x: 88.6%
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 60 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4933416C03Rik T C 10: 116,113,616 S2G probably damaging Het
Adgra2 T C 8: 27,110,018 probably null Het
Adgrb2 T C 4: 129,992,837 S257P probably benign Het
Adgre1 A G 17: 57,441,353 K518E probably benign Het
Anxa7 A T 14: 20,464,615 Y64* probably null Het
Arhgef7 A G 8: 11,782,638 probably null Het
Cdc42bpa T A 1: 180,065,001 Y243* probably null Het
Cdk14 C T 5: 5,135,378 V176M probably damaging Het
Cnbd2 A G 2: 156,333,631 E54G probably damaging Het
Crx T C 7: 15,867,811 probably null Het
Cyp24a1 A G 2: 170,485,691 F511L possibly damaging Het
Ddx11 A G 17: 66,150,385 M810V probably damaging Het
Dock10 T C 1: 80,549,802 T1077A probably benign Het
Dopey1 G A 9: 86,536,250 D2011N probably damaging Het
Ehhadh T A 16: 21,766,408 H241L probably benign Het
Enah A T 1: 181,919,620 L523* probably null Het
Fabp3 T C 4: 130,308,848 L24P probably benign Het
Fat2 A G 11: 55,282,010 S2626P probably benign Het
Fbxo4 A G 15: 3,968,965 M337T possibly damaging Het
Gas6 G T 8: 13,465,786 T662N probably damaging Het
Gm10608 CAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA CAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA 9: 119,160,716 probably null Het
Hrh4 G A 18: 13,015,898 V106I possibly damaging Het
Ido2 G T 8: 24,576,189 H20Q possibly damaging Het
Ikbkap T A 4: 56,774,756 K740* probably null Het
Itga10 G T 3: 96,653,658 R613L possibly damaging Het
Itsn2 T C 12: 4,658,452 S836P probably benign Het
Kcng3 A T 17: 83,588,339 C233S probably damaging Het
Kdm3b A G 18: 34,808,731 Q625R probably damaging Het
Kidins220 A G 12: 25,005,088 S553G probably benign Het
Krt82 A T 15: 101,545,153 I266N probably damaging Het
Lama5 A T 2: 180,197,745 L736Q probably damaging Het
Lnx2 A G 5: 147,033,519 C138R probably damaging Het
Mcm5 T C 8: 75,119,354 C397R possibly damaging Het
Me1 A C 9: 86,678,012 Y52D probably damaging Het
Muc4 C A 16: 32,755,501 probably benign Het
Myo18b G T 5: 112,871,498 Q638K possibly damaging Het
Ncapd2 A G 6: 125,185,772 L170P probably damaging Het
Neb A T 2: 52,287,252 L1359* probably null Het
Nomo1 C A 7: 46,046,955 S299Y probably damaging Het
Olfr1359 C A 13: 21,703,226 T75K probably damaging Het
Olfr1509 A C 14: 52,450,442 T10P probably benign Het
Olfr322 A T 11: 58,666,077 R173W probably damaging Het
Olfr57 A T 10: 79,035,504 Y236F possibly damaging Het
Onecut1 A T 9: 74,862,691 H132L probably benign Het
Paqr3 A G 5: 97,111,389 Y19H probably benign Het
Prdx5 T C 19: 6,907,558 H140R possibly damaging Het
Prox1 T C 1: 190,161,006 D414G probably damaging Het
Ptprh T G 7: 4,552,638 E774A probably damaging Het
Rnpepl1 A T 1: 92,917,222 D412V possibly damaging Het
Sars2 C T 7: 28,748,971 T259M probably benign Het
Sbf2 T C 7: 110,340,076 probably null Het
Sbno2 C T 10: 80,060,492 R898H probably damaging Het
Smox C A 2: 131,520,174 T172N probably damaging Het
Tdrd9 C T 12: 112,023,253 R341* probably null Het
Thrap3 C G 4: 126,180,101 G284A probably damaging Het
Tmtc4 A G 14: 122,944,826 V271A probably benign Het
Trank1 A G 9: 111,373,477 T1637A probably damaging Het
Tspan5 T A 3: 138,896,835 I166N probably damaging Het
Vps13b T C 15: 35,642,436 V1398A probably benign Het
Xbp1 C T 11: 5,521,975 R34W probably damaging Het
Other mutations in 1110032F04Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0433:1110032F04Rik UTSW 3 68870303 missense possibly damaging 0.51
R1603:1110032F04Rik UTSW 3 68870213 missense probably benign
R4591:1110032F04Rik UTSW 3 68870266 missense possibly damaging 0.86
R4832:1110032F04Rik UTSW 3 68870264 missense possibly damaging 0.51
Predicted Primers PCR Primer
(F):5'- CAAGCTCTCTGGGCTGCTCATC -3'
(R):5'- ATCCCCATGAGGCTCCCTGAAC -3'

Sequencing Primer
(F):5'- GCAGCGCATCATCTGCC -3'
(R):5'- AGGCTCCCTGAACTCAGATG -3'
Posted On2014-04-24