Incidental Mutation 'IGL02007:Cyp3a16'
ID182258
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Cyp3a16
Ensembl Gene ENSMUSG00000038656
Gene Namecytochrome P450, family 3, subfamily a, polypeptide 16
Synonyms
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.436) question?
Stock #IGL02007
Quality Score
Status
Chromosome5
Chromosomal Location145436309-145469723 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to C at 145441948 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000031633 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000031633]
Predicted Effect probably benign
Transcript: ENSMUST00000031633
SMART Domains Protein: ENSMUSP00000031633
Gene: ENSMUSG00000038656

DomainStartEndE-ValueType
low complexity region 3 22 N/A INTRINSIC
Pfam:p450 38 494 5.5e-132 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 28 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adam28 C A 14: 68,633,219 R335L possibly damaging Het
Adgrv1 T C 13: 81,568,743 probably benign Het
Calcrl A G 2: 84,375,324 C8R probably benign Het
Cntn4 T A 6: 106,655,529 S505T probably benign Het
Fam160a1 G T 3: 85,722,445 P280T probably damaging Het
Gm11127 G T 17: 36,056,330 N333K possibly damaging Het
Gpatch11 A G 17: 78,842,164 T198A probably benign Het
Heatr5a C A 12: 51,916,158 L986F probably damaging Het
Ift172 A G 5: 31,286,604 I90T probably benign Het
Igkv3-9 A G 6: 70,588,461 probably benign Het
Iqsec1 G A 6: 90,690,349 P369S probably benign Het
Myh1 C A 11: 67,220,556 T1607K probably benign Het
Myo18b T C 5: 112,874,972 probably benign Het
Nobox A G 6: 43,307,538 L58P probably damaging Het
Nwd2 T A 5: 63,804,699 I542N possibly damaging Het
Olfr1301 A G 2: 111,754,479 T77A probably damaging Het
Olfr474 A G 7: 107,954,746 Y35C probably damaging Het
Osm C T 11: 4,239,470 R85W probably damaging Het
Pcdh20 T C 14: 88,469,595 R90G probably benign Het
Pkhd1l1 T C 15: 44,533,733 probably benign Het
Sec14l2 A G 11: 4,111,114 S116P probably benign Het
Selenbp2 A C 3: 94,698,154 N96H possibly damaging Het
Smarcal1 T C 1: 72,595,940 S393P probably damaging Het
Tbc1d1 A G 5: 64,256,992 Q103R probably damaging Het
Tmem63c T C 12: 87,072,873 Y314H probably damaging Het
Wdr34 A G 2: 30,038,390 S75P probably benign Het
Zfp663 A C 2: 165,359,073 S14A probably benign Het
Zmynd10 A G 9: 107,550,532 N345S probably damaging Het
Other mutations in Cyp3a16
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01386:Cyp3a16 APN 5 145440434 missense probably damaging 0.98
IGL01964:Cyp3a16 APN 5 145455562 missense probably benign 0.41
IGL02139:Cyp3a16 APN 5 145455480 missense probably benign 0.10
IGL02177:Cyp3a16 APN 5 145450154 missense probably benign 0.43
IGL02407:Cyp3a16 APN 5 145451842 missense probably damaging 0.99
IGL02473:Cyp3a16 APN 5 145440494 missense possibly damaging 0.54
R0363:Cyp3a16 UTSW 5 145455879 splice site probably benign
R0556:Cyp3a16 UTSW 5 145455980 missense probably benign 0.37
R0557:Cyp3a16 UTSW 5 145469588 missense unknown
R0636:Cyp3a16 UTSW 5 145463085 missense probably benign 0.03
R0749:Cyp3a16 UTSW 5 145456177 critical splice acceptor site probably null
R0788:Cyp3a16 UTSW 5 145465076 missense probably benign 0.00
R1552:Cyp3a16 UTSW 5 145436536 missense probably benign 0.01
R1575:Cyp3a16 UTSW 5 145436457 missense probably benign 0.01
R1580:Cyp3a16 UTSW 5 145442074 missense possibly damaging 0.94
R1580:Cyp3a16 UTSW 5 145442075 missense probably damaging 1.00
R1642:Cyp3a16 UTSW 5 145469589 missense unknown
R1763:Cyp3a16 UTSW 5 145465031 critical splice donor site probably null
R2029:Cyp3a16 UTSW 5 145451857 missense probably damaging 0.96
R2144:Cyp3a16 UTSW 5 145456084 missense probably damaging 1.00
R2409:Cyp3a16 UTSW 5 145440367 missense probably benign 0.01
R2473:Cyp3a16 UTSW 5 145455594 missense possibly damaging 0.79
R2860:Cyp3a16 UTSW 5 145455499 nonsense probably null
R2861:Cyp3a16 UTSW 5 145455499 nonsense probably null
R3747:Cyp3a16 UTSW 5 145442071 missense probably damaging 1.00
R4654:Cyp3a16 UTSW 5 145436457 missense probably benign 0.01
R4781:Cyp3a16 UTSW 5 145456112 missense possibly damaging 0.85
R4873:Cyp3a16 UTSW 5 145452849 missense probably benign 0.01
R4875:Cyp3a16 UTSW 5 145452849 missense probably benign 0.01
R4925:Cyp3a16 UTSW 5 145452834 missense probably benign 0.00
R5365:Cyp3a16 UTSW 5 145452787 missense probably damaging 1.00
R5496:Cyp3a16 UTSW 5 145467531 missense probably damaging 1.00
R5640:Cyp3a16 UTSW 5 145452823 missense possibly damaging 0.94
R5761:Cyp3a16 UTSW 5 145442033 missense possibly damaging 0.79
R6401:Cyp3a16 UTSW 5 145440364 missense probably damaging 1.00
R6526:Cyp3a16 UTSW 5 145455895 missense probably benign 0.01
R6528:Cyp3a16 UTSW 5 145440431 missense probably damaging 1.00
R7000:Cyp3a16 UTSW 5 145463170 critical splice acceptor site probably null
Posted On2014-05-07