Incidental Mutation 'R2055:Nckap5'
| ID |
226563 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nckap5
|
| Ensembl Gene |
ENSMUSG00000049690 |
| Gene Name |
NCK-associated protein 5 |
| Synonyms |
LOC380609, D130011D22Rik, E030049G20Rik |
| MMRRC Submission |
040060-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2055 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
125841373-126758529 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 125954635 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 639
(E639G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125624
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000057846]
[ENSMUST00000094609]
[ENSMUST00000094610]
[ENSMUST00000112583]
[ENSMUST00000161954]
[ENSMUST00000162877]
|
| AlphaFold |
E9QAE1 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000057846
AA Change: E575G
PolyPhen 2
Score 0.682 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000062229
Gene: ENSMUSG00000049690
AA Change: E575G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
25 |
N/A |
INTRINSIC |
|
coiled coil region
|
108 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
321 |
332 |
N/A |
INTRINSIC |
|
low complexity region
|
755 |
771 |
N/A |
INTRINSIC |
|
low complexity region
|
950 |
971 |
N/A |
INTRINSIC |
|
low complexity region
|
1070 |
1085 |
N/A |
INTRINSIC |
|
low complexity region
|
1181 |
1200 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1298 |
1602 |
1.8e-120 |
PFAM |
|
low complexity region
|
1728 |
1742 |
N/A |
INTRINSIC |
|
low complexity region
|
1757 |
1771 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094609
|
| SMART Domains |
Protein: ENSMUSP00000092192
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
93 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
113 |
364 |
3.6e-36 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094610
|
| SMART Domains |
Protein: ENSMUSP00000092193
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NCKAP5
|
1 |
101 |
8.8e-42 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112583
AA Change: E707G
PolyPhen 2
Score 0.428 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000108202
Gene: ENSMUSG00000049690
AA Change: E707G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
93 |
N/A |
INTRINSIC |
|
coiled coil region
|
176 |
254 |
N/A |
INTRINSIC |
|
low complexity region
|
301 |
324 |
N/A |
INTRINSIC |
|
low complexity region
|
453 |
464 |
N/A |
INTRINSIC |
|
low complexity region
|
887 |
903 |
N/A |
INTRINSIC |
|
low complexity region
|
1082 |
1103 |
N/A |
INTRINSIC |
|
low complexity region
|
1202 |
1217 |
N/A |
INTRINSIC |
|
low complexity region
|
1313 |
1332 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1431 |
1733 |
5.3e-119 |
PFAM |
|
low complexity region
|
1860 |
1874 |
N/A |
INTRINSIC |
|
low complexity region
|
1889 |
1903 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000159934
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000161954
AA Change: E639G
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000125624
Gene: ENSMUSG00000049690
AA Change: E639G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
25 |
N/A |
INTRINSIC |
|
coiled coil region
|
108 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
233 |
256 |
N/A |
INTRINSIC |
|
low complexity region
|
385 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
1014 |
1035 |
N/A |
INTRINSIC |
|
low complexity region
|
1134 |
1149 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1264 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1362 |
1666 |
2.1e-120 |
PFAM |
|
low complexity region
|
1792 |
1806 |
N/A |
INTRINSIC |
|
low complexity region
|
1821 |
1835 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162877
|
| SMART Domains |
Protein: ENSMUSP00000124748
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NCKAP5
|
9 |
296 |
6e-36 |
PFAM |
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.3%
|
| Validation Efficiency |
100% (74/74) |
| Allele List at MGI |
All alleles(1) : Gene trapped(1) |
| Other mutations in this stock |
Total: 74 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700123K08Rik |
T |
C |
5: 138,561,107 (GRCm39) |
E185G |
probably damaging |
Het |
| 3425401B19Rik |
A |
G |
14: 32,384,508 (GRCm39) |
S486P |
probably benign |
Het |
| A630023A22Rik |
T |
C |
14: 33,774,707 (GRCm39) |
|
probably benign |
Het |
| Abca1 |
T |
C |
4: 53,069,881 (GRCm39) |
N1271S |
probably benign |
Het |
| AI597479 |
C |
T |
1: 43,150,280 (GRCm39) |
A130V |
probably benign |
Het |
| Angptl4 |
A |
G |
17: 33,999,498 (GRCm39) |
|
probably null |
Het |
| Arhgef25 |
T |
A |
10: 127,021,004 (GRCm39) |
N294I |
probably damaging |
Het |
| Atp2b1 |
T |
C |
10: 98,850,421 (GRCm39) |
V848A |
probably damaging |
Het |
| Bard1 |
T |
C |
1: 71,114,031 (GRCm39) |
T317A |
probably benign |
Het |
| C1rl |
T |
C |
6: 124,470,781 (GRCm39) |
W30R |
probably benign |
Het |
| Cchcr1 |
A |
G |
17: 35,837,317 (GRCm39) |
E379G |
probably damaging |
Het |
| Cfap36 |
G |
T |
11: 29,197,122 (GRCm39) |
A3E |
probably damaging |
Het |
| Cilp |
G |
A |
9: 65,186,997 (GRCm39) |
G1031S |
probably damaging |
Het |
| Clca4a |
A |
G |
3: 144,676,489 (GRCm39) |
Y64H |
probably damaging |
Het |
| Cops5 |
A |
G |
1: 10,102,562 (GRCm39) |
|
probably null |
Het |
| Cracr2a |
G |
T |
6: 127,585,564 (GRCm39) |
E121* |
probably null |
Het |
| Cstf1 |
A |
G |
2: 172,222,403 (GRCm39) |
E387G |
probably benign |
Het |
| D630044L22Rik |
A |
C |
17: 26,180,951 (GRCm39) |
D733E |
probably damaging |
Het |
| Dlc1 |
A |
T |
8: 37,060,535 (GRCm39) |
C514S |
probably damaging |
Het |
| Dmwd |
G |
T |
7: 18,810,610 (GRCm39) |
R139L |
probably benign |
Het |
| Dnah17 |
A |
T |
11: 117,958,357 (GRCm39) |
S2709T |
probably benign |
Het |
| Dnmt3a |
T |
C |
12: 3,922,859 (GRCm39) |
I154T |
probably benign |
Het |
| Dpp7 |
T |
C |
2: 25,244,490 (GRCm39) |
N297S |
possibly damaging |
Het |
| Ern2 |
A |
T |
7: 121,783,168 (GRCm39) |
V34D |
possibly damaging |
Het |
| Erp27 |
A |
G |
6: 136,885,227 (GRCm39) |
|
probably benign |
Het |
| F2 |
T |
C |
2: 91,458,787 (GRCm39) |
T508A |
probably benign |
Het |
| Fam181b |
A |
G |
7: 92,729,634 (GRCm39) |
T136A |
probably benign |
Het |
| Fam227b |
C |
A |
2: 125,942,874 (GRCm39) |
V308L |
probably benign |
Het |
| Fbxw20 |
A |
T |
9: 109,050,442 (GRCm39) |
H394Q |
probably damaging |
Het |
| G530012D18Rik |
CAGAGAGA |
CAGAGAGAGA |
1: 85,504,945 (GRCm39) |
|
probably null |
Het |
| Glt8d1 |
T |
G |
14: 30,731,693 (GRCm39) |
S111A |
probably benign |
Het |
| Gm11146 |
A |
T |
16: 77,391,969 (GRCm39) |
|
probably benign |
Het |
| Grip1 |
C |
T |
10: 119,885,416 (GRCm39) |
|
probably benign |
Het |
| H2-Q2 |
A |
T |
17: 35,564,247 (GRCm39) |
T334S |
probably benign |
Het |
| Hcrtr1 |
A |
G |
4: 130,024,680 (GRCm39) |
V402A |
probably benign |
Het |
| Hmcn2 |
C |
A |
2: 31,268,294 (GRCm39) |
A1130D |
probably benign |
Het |
| Hsd17b2 |
T |
C |
8: 118,428,913 (GRCm39) |
L60P |
possibly damaging |
Het |
| Htr1f |
A |
T |
16: 64,746,398 (GRCm39) |
I298N |
probably damaging |
Het |
| Ighmbp2 |
G |
T |
19: 3,315,095 (GRCm39) |
A775D |
probably benign |
Het |
| Kcnn3 |
A |
G |
3: 89,428,682 (GRCm39) |
T303A |
probably damaging |
Het |
| Kiz |
C |
A |
2: 146,733,203 (GRCm39) |
Q460K |
probably benign |
Het |
| Krt75 |
C |
T |
15: 101,481,196 (GRCm39) |
V193I |
probably benign |
Het |
| Lsp1 |
G |
A |
7: 142,043,144 (GRCm39) |
|
probably null |
Het |
| Mfsd12 |
A |
G |
10: 81,196,063 (GRCm39) |
H146R |
probably damaging |
Het |
| Mmp23 |
T |
C |
4: 155,736,444 (GRCm39) |
K199R |
possibly damaging |
Het |
| Naip2 |
A |
G |
13: 100,315,880 (GRCm39) |
V300A |
probably benign |
Het |
| Nbeal1 |
C |
T |
1: 60,350,216 (GRCm39) |
L2422F |
probably damaging |
Het |
| Nbeal2 |
G |
T |
9: 110,464,375 (GRCm39) |
D1094E |
possibly damaging |
Het |
| Nr4a3 |
A |
G |
4: 48,067,771 (GRCm39) |
I456V |
possibly damaging |
Het |
| Or2t43 |
A |
G |
11: 58,457,673 (GRCm39) |
F166S |
probably damaging |
Het |
| Parp9 |
G |
T |
16: 35,773,984 (GRCm39) |
V86L |
probably damaging |
Het |
| Phactr1 |
A |
G |
13: 43,231,416 (GRCm39) |
N386S |
probably damaging |
Het |
| Pold2 |
A |
T |
11: 5,823,516 (GRCm39) |
Y304* |
probably null |
Het |
| Pou5f2 |
A |
G |
13: 78,173,940 (GRCm39) |
Y294C |
probably benign |
Het |
| Rars1 |
A |
G |
11: 35,717,410 (GRCm39) |
|
probably benign |
Het |
| Rbm12b1 |
A |
G |
4: 12,145,606 (GRCm39) |
E526G |
probably benign |
Het |
| Sacs |
T |
C |
14: 61,451,498 (GRCm39) |
Y4515H |
probably damaging |
Het |
| Sdk2 |
C |
A |
11: 113,741,780 (GRCm39) |
R813L |
probably damaging |
Het |
| Six5 |
T |
C |
7: 18,829,154 (GRCm39) |
V198A |
possibly damaging |
Het |
| Slco1a7 |
A |
T |
6: 141,671,181 (GRCm39) |
H430Q |
probably benign |
Het |
| Spata31e2 |
A |
T |
1: 26,724,813 (GRCm39) |
N122K |
possibly damaging |
Het |
| Spn |
A |
G |
7: 126,736,388 (GRCm39) |
S40P |
probably damaging |
Het |
| Ssr1 |
A |
G |
13: 38,171,761 (GRCm39) |
|
probably benign |
Het |
| Tlr6 |
C |
A |
5: 65,111,269 (GRCm39) |
C546F |
probably damaging |
Het |
| Top1 |
T |
A |
2: 160,544,748 (GRCm39) |
|
probably benign |
Het |
| Trhr2 |
A |
G |
8: 123,085,532 (GRCm39) |
S151P |
probably damaging |
Het |
| Tubb2b |
T |
G |
13: 34,311,708 (GRCm39) |
K362Q |
probably benign |
Het |
| Unc13c |
T |
C |
9: 73,643,832 (GRCm39) |
T1211A |
probably damaging |
Het |
| Vmn1r15 |
T |
C |
6: 57,235,729 (GRCm39) |
V199A |
possibly damaging |
Het |
| Vnn1 |
A |
G |
10: 23,776,475 (GRCm39) |
|
probably benign |
Het |
| Vps41 |
T |
A |
13: 19,038,786 (GRCm39) |
N737K |
possibly damaging |
Het |
| Vps50 |
T |
A |
6: 3,522,265 (GRCm39) |
N144K |
probably benign |
Het |
| Zc3h7a |
A |
T |
16: 10,955,340 (GRCm39) |
N911K |
probably benign |
Het |
| Zkscan7 |
T |
A |
9: 122,718,002 (GRCm39) |
S132R |
probably damaging |
Het |
|
| Other mutations in Nckap5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00833:Nckap5
|
APN |
1 |
125,954,889 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00956:Nckap5
|
APN |
1 |
125,952,755 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01414:Nckap5
|
APN |
1 |
126,456,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01482:Nckap5
|
APN |
1 |
125,950,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01508:Nckap5
|
APN |
1 |
125,953,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02071:Nckap5
|
APN |
1 |
125,909,305 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02129:Nckap5
|
APN |
1 |
125,955,432 (GRCm39) |
nonsense |
probably null |
|
|
IGL02821:Nckap5
|
APN |
1 |
125,955,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03174:Nckap5
|
APN |
1 |
125,909,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
F5493:Nckap5
|
UTSW |
1 |
125,953,564 (GRCm39) |
missense |
probably benign |
|
|
G5030:Nckap5
|
UTSW |
1 |
125,953,591 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0033:Nckap5
|
UTSW |
1 |
125,867,979 (GRCm39) |
intron |
probably benign |
|
|
R0164:Nckap5
|
UTSW |
1 |
125,952,144 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0164:Nckap5
|
UTSW |
1 |
125,952,144 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0349:Nckap5
|
UTSW |
1 |
125,954,171 (GRCm39) |
missense |
probably benign |
|
|
R0482:Nckap5
|
UTSW |
1 |
125,954,102 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0508:Nckap5
|
UTSW |
1 |
125,909,121 (GRCm39) |
splice site |
probably null |
|
|
R0541:Nckap5
|
UTSW |
1 |
126,623,459 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R0609:Nckap5
|
UTSW |
1 |
125,955,025 (GRCm39) |
nonsense |
probably null |
|
|
R0701:Nckap5
|
UTSW |
1 |
125,953,094 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0782:Nckap5
|
UTSW |
1 |
125,909,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1389:Nckap5
|
UTSW |
1 |
125,954,447 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1401:Nckap5
|
UTSW |
1 |
125,942,398 (GRCm39) |
splice site |
probably benign |
|
|
R1436:Nckap5
|
UTSW |
1 |
125,953,798 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R1506:Nckap5
|
UTSW |
1 |
125,953,650 (GRCm39) |
nonsense |
probably null |
|
|
R1528:Nckap5
|
UTSW |
1 |
125,952,659 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1942:Nckap5
|
UTSW |
1 |
125,952,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1968:Nckap5
|
UTSW |
1 |
125,942,367 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2105:Nckap5
|
UTSW |
1 |
125,954,255 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2214:Nckap5
|
UTSW |
1 |
125,953,487 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R2311:Nckap5
|
UTSW |
1 |
126,456,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2403:Nckap5
|
UTSW |
1 |
125,955,146 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2430:Nckap5
|
UTSW |
1 |
125,842,494 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2914:Nckap5
|
UTSW |
1 |
125,954,274 (GRCm39) |
splice site |
probably null |
|
|
R3782:Nckap5
|
UTSW |
1 |
125,952,811 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4133:Nckap5
|
UTSW |
1 |
126,150,443 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4249:Nckap5
|
UTSW |
1 |
125,955,376 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4448:Nckap5
|
UTSW |
1 |
125,953,463 (GRCm39) |
nonsense |
probably null |
|
|
R4456:Nckap5
|
UTSW |
1 |
125,842,472 (GRCm39) |
unclassified |
probably benign |
|
|
R4682:Nckap5
|
UTSW |
1 |
126,030,279 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4817:Nckap5
|
UTSW |
1 |
125,954,952 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4907:Nckap5
|
UTSW |
1 |
125,953,889 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4908:Nckap5
|
UTSW |
1 |
125,955,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4924:Nckap5
|
UTSW |
1 |
125,954,765 (GRCm39) |
nonsense |
probably null |
|
|
R4926:Nckap5
|
UTSW |
1 |
126,456,378 (GRCm39) |
intron |
probably benign |
|
|
R5032:Nckap5
|
UTSW |
1 |
125,904,786 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R5133:Nckap5
|
UTSW |
1 |
125,961,697 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5197:Nckap5
|
UTSW |
1 |
126,150,410 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5238:Nckap5
|
UTSW |
1 |
125,955,461 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5257:Nckap5
|
UTSW |
1 |
125,952,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5277:Nckap5
|
UTSW |
1 |
125,954,277 (GRCm39) |
nonsense |
probably null |
|
|
R5512:Nckap5
|
UTSW |
1 |
125,955,481 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5700:Nckap5
|
UTSW |
1 |
125,904,662 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5789:Nckap5
|
UTSW |
1 |
125,955,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6029:Nckap5
|
UTSW |
1 |
125,953,523 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6249:Nckap5
|
UTSW |
1 |
125,952,667 (GRCm39) |
missense |
probably benign |
|
|
R6292:Nckap5
|
UTSW |
1 |
125,842,752 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6521:Nckap5
|
UTSW |
1 |
126,309,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6875:Nckap5
|
UTSW |
1 |
125,950,931 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7017:Nckap5
|
UTSW |
1 |
126,030,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7018:Nckap5
|
UTSW |
1 |
125,952,785 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7054:Nckap5
|
UTSW |
1 |
126,186,449 (GRCm39) |
splice site |
probably null |
|
|
R7204:Nckap5
|
UTSW |
1 |
125,954,104 (GRCm39) |
missense |
probably benign |
|
|
R7336:Nckap5
|
UTSW |
1 |
125,953,786 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7544:Nckap5
|
UTSW |
1 |
125,953,948 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7590:Nckap5
|
UTSW |
1 |
125,954,270 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7684:Nckap5
|
UTSW |
1 |
125,954,594 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7749:Nckap5
|
UTSW |
1 |
125,952,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7773:Nckap5
|
UTSW |
1 |
125,954,581 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7813:Nckap5
|
UTSW |
1 |
125,953,163 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7970:Nckap5
|
UTSW |
1 |
125,952,758 (GRCm39) |
nonsense |
probably null |
|
|
R7992:Nckap5
|
UTSW |
1 |
125,954,547 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8278:Nckap5
|
UTSW |
1 |
125,955,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8373:Nckap5
|
UTSW |
1 |
125,954,032 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8414:Nckap5
|
UTSW |
1 |
125,942,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8755:Nckap5
|
UTSW |
1 |
125,954,279 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8845:Nckap5
|
UTSW |
1 |
125,909,423 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9016:Nckap5
|
UTSW |
1 |
126,623,491 (GRCm39) |
start codon destroyed |
probably null |
0.01 |
|
R9209:Nckap5
|
UTSW |
1 |
125,867,928 (GRCm39) |
missense |
unknown |
|
|
R9214:Nckap5
|
UTSW |
1 |
125,942,376 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9300:Nckap5
|
UTSW |
1 |
125,909,423 (GRCm39) |
nonsense |
probably null |
|
|
R9464:Nckap5
|
UTSW |
1 |
125,952,494 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9572:Nckap5
|
UTSW |
1 |
125,955,454 (GRCm39) |
missense |
probably benign |
0.41 |
|
R9721:Nckap5
|
UTSW |
1 |
125,955,017 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9748:Nckap5
|
UTSW |
1 |
125,953,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Nckap5
|
UTSW |
1 |
125,952,569 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
Z1176:Nckap5
|
UTSW |
1 |
126,456,418 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1177:Nckap5
|
UTSW |
1 |
126,150,396 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TTCTGAGGTGAAGACTTGCC -3'
(R):5'- AATTCAGCTCTCACCAGGCTG -3'
Sequencing Primer
(F):5'- AGACCTTGCTTTGTGTAGACAC -3'
(R):5'- TGGAGTCGTCACTGTCACCAG -3'
|
| Posted On |
2014-09-17 |
Incidental Mutation