Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02614:Gm1110'

300600

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm1110

Ensembl Gene

ENSMUSG00000079644

Gene Name

predicted gene 1110

Synonyms

LOC382064

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.069) question?

Stock #

IGL02614

Quality Score

Status

Chromosome

Chromosomal Location

26790863-26834407 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 26832010 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 47 (V47A)

Ref Sequence

ENSEMBL: ENSMUSP00000110916 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000115261]

AlphaFold

F6Y113

Predicted Effect

probably benign
Transcript: ENSMUST00000115261
AA Change: V47A

PolyPhen 2 Score 0.106 (Sensitivity: 0.93; Specificity: 0.86)

SMART Domains

Protein: ENSMUSP00000110916
Gene: ENSMUSG00000079644
AA Change: V47A

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
Pfam:Glyco_hydro_35	55	368	2e-93	PFAM
Pfam:Glyco_hydro_42	70	229	1e-12	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000214461

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000217197

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 35 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aasdh	A	T	5: 77,044,215 (GRCm39)		probably benign	Het
Acadsb	A	G	7: 131,026,357 (GRCm39)	T67A	probably benign	Het
Aff2	A	G	X: 68,907,693 (GRCm39)	D1225G	possibly damaging	Het
Atp2a2	T	C	5: 122,627,366 (GRCm39)	D133G	probably benign	Het
Cacul1	A	T	19: 60,551,661 (GRCm39)	M187K	possibly damaging	Het
Celf4	A	G	18: 25,637,207 (GRCm39)	Y263H	probably damaging	Het
Cmbl	G	T	15: 31,589,830 (GRCm39)	V187F	probably damaging	Het
Epha1	T	C	6: 42,337,491 (GRCm39)	N896S	probably benign	Het
Fbxo27	G	A	7: 28,396,201 (GRCm39)		probably null	Het
Galnt16	T	C	12: 80,623,337 (GRCm39)	S166P	probably damaging	Het
Gmnn	A	G	13: 24,944,137 (GRCm39)		probably benign	Het
Gpbp1	T	C	13: 111,573,007 (GRCm39)	I382V	probably benign	Het
Gpr87	C	A	3: 59,086,738 (GRCm39)	V256L	probably damaging	Het
Il4ra	C	A	7: 125,174,962 (GRCm39)	S390*	probably null	Het
Itprid1	A	T	6: 55,945,262 (GRCm39)	D661V	probably damaging	Het
Lrrc47	T	C	4: 154,103,392 (GRCm39)		probably null	Het
Lrriq4	A	T	3: 30,709,788 (GRCm39)	L362F	probably damaging	Het
Lrrtm4	A	T	6: 79,998,827 (GRCm39)	N79Y	probably benign	Het
Nr1i2	T	A	16: 38,074,118 (GRCm39)	H165L	probably damaging	Het
Or10g1b	T	C	14: 52,627,627 (GRCm39)	E201G	probably damaging	Het
Phf11a	T	A	14: 59,516,817 (GRCm39)	T214S	possibly damaging	Het
Prr14l	A	T	5: 32,987,887 (GRCm39)	I536K	possibly damaging	Het
Rpn1	T	A	6: 88,079,087 (GRCm39)	I510N	probably benign	Het
Sall4	A	T	2: 168,597,805 (GRCm39)	L20Q	probably null	Het
Sema3f	T	C	9: 107,559,710 (GRCm39)	E759G	probably benign	Het
Slc5a1	T	C	5: 33,311,945 (GRCm39)	S446P	probably benign	Het
Srrm1	G	A	4: 135,052,415 (GRCm39)	P658L	unknown	Het
Tcn2	C	A	11: 3,876,158 (GRCm39)	S90I	possibly damaging	Het
Ttn	T	C	2: 76,542,331 (GRCm39)	T31806A	possibly damaging	Het
Ubr1	T	C	2: 120,701,460 (GRCm39)		probably benign	Het
Vac14	T	G	8: 111,361,750 (GRCm39)	L214R	probably damaging	Het
Vmn2r58	T	C	7: 41,486,553 (GRCm39)	K781E	probably damaging	Het
Vmn2r92	T	C	17: 18,387,503 (GRCm39)		probably benign	Het
Zfp518a	G	A	19: 40,903,061 (GRCm39)	G997R	probably damaging	Het
Zfp609	G	A	9: 65,610,072 (GRCm39)	P964S	probably damaging	Het

Other mutations in Gm1110

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00591:Gm1110	APN	9	26,792,170 (GRCm39)	nonsense	probably null
IGL01089:Gm1110	APN	9	26,793,156 (GRCm39)	missense	probably benign
IGL01631:Gm1110	APN	9	26,809,212 (GRCm39)	critical splice donor site	probably null
IGL02008:Gm1110	APN	9	26,794,526 (GRCm39)	missense	probably benign	0.09
IGL02331:Gm1110	APN	9	26,824,583 (GRCm39)	critical splice donor site	probably null
IGL02335:Gm1110	APN	9	26,793,059 (GRCm39)	missense	probably benign	0.00
IGL02550:Gm1110	APN	9	26,793,130 (GRCm39)	missense	probably benign	0.09
IGL03409:Gm1110	APN	9	26,807,916 (GRCm39)	missense	probably benign	0.21
PIT4458001:Gm1110	UTSW	9	26,792,124 (GRCm39)	missense	probably benign	0.00
R0189:Gm1110	UTSW	9	26,794,514 (GRCm39)	missense	probably null	0.99
R0271:Gm1110	UTSW	9	26,831,962 (GRCm39)	missense	probably damaging	1.00
R1034:Gm1110	UTSW	9	26,832,646 (GRCm39)	missense	probably damaging	1.00
R1229:Gm1110	UTSW	9	26,793,102 (GRCm39)	missense	probably benign
R1355:Gm1110	UTSW	9	26,795,057 (GRCm39)	missense	probably benign	0.01
R1566:Gm1110	UTSW	9	26,792,166 (GRCm39)	missense	probably damaging	1.00
R1574:Gm1110	UTSW	9	26,792,422 (GRCm39)	splice site	probably benign
R1916:Gm1110	UTSW	9	26,800,934 (GRCm39)	missense	probably damaging	1.00
R2011:Gm1110	UTSW	9	26,805,554 (GRCm39)	missense	probably benign	0.01
R2214:Gm1110	UTSW	9	26,813,786 (GRCm39)	missense	probably benign	0.37
R2567:Gm1110	UTSW	9	26,831,992 (GRCm39)	missense	probably benign
R2967:Gm1110	UTSW	9	26,792,339 (GRCm39)	missense	probably benign	0.05
R4271:Gm1110	UTSW	9	26,806,944 (GRCm39)	critical splice donor site	probably null
R4683:Gm1110	UTSW	9	26,831,890 (GRCm39)	missense	probably damaging	0.99
R4945:Gm1110	UTSW	9	26,831,891 (GRCm39)	missense	possibly damaging	0.46
R5015:Gm1110	UTSW	9	26,793,162 (GRCm39)	missense	probably benign	0.01
R5089:Gm1110	UTSW	9	26,793,683 (GRCm39)	missense	probably damaging	0.96
R5225:Gm1110	UTSW	9	26,813,774 (GRCm39)	missense	probably damaging	1.00
R5239:Gm1110	UTSW	9	26,804,866 (GRCm39)	missense	probably benign	0.00
R5395:Gm1110	UTSW	9	26,800,928 (GRCm39)	missense	probably benign
R5783:Gm1110	UTSW	9	26,793,632 (GRCm39)	missense	probably benign
R6045:Gm1110	UTSW	9	26,794,505 (GRCm39)	critical splice donor site	probably null
R6245:Gm1110	UTSW	9	26,832,043 (GRCm39)	missense	probably benign	0.04
R6357:Gm1110	UTSW	9	26,825,424 (GRCm39)	splice site	probably null
R6863:Gm1110	UTSW	9	26,792,360 (GRCm39)	missense	probably damaging	1.00
R7336:Gm1110	UTSW	9	26,825,653 (GRCm39)	missense	probably damaging	0.99
R7454:Gm1110	UTSW	9	26,831,945 (GRCm39)	missense	probably benign
R7555:Gm1110	UTSW	9	26,804,924 (GRCm39)	missense	probably benign	0.05
R7579:Gm1110	UTSW	9	26,795,122 (GRCm39)	missense	possibly damaging	0.93
R7990:Gm1110	UTSW	9	26,792,137 (GRCm39)	missense	possibly damaging	0.66
R8062:Gm1110	UTSW	9	26,793,117 (GRCm39)	missense	probably damaging	0.99
R8108:Gm1110	UTSW	9	26,831,957 (GRCm39)	missense	probably damaging	1.00
R8323:Gm1110	UTSW	9	26,813,719 (GRCm39)	critical splice donor site	probably null
R8354:Gm1110	UTSW	9	26,794,577 (GRCm39)	missense	probably benign	0.00
R8354:Gm1110	UTSW	9	26,794,576 (GRCm39)	missense	probably benign	0.01
R8454:Gm1110	UTSW	9	26,794,577 (GRCm39)	missense	probably benign	0.00
R8454:Gm1110	UTSW	9	26,794,576 (GRCm39)	missense	probably benign	0.01
R8494:Gm1110	UTSW	9	26,792,154 (GRCm39)	missense	probably benign	0.04
R8978:Gm1110	UTSW	9	26,807,095 (GRCm39)	splice site	probably benign
R9321:Gm1110	UTSW	9	26,831,891 (GRCm39)	missense	probably benign	0.00
R9513:Gm1110	UTSW	9	26,795,083 (GRCm39)	missense	possibly damaging	0.95
R9545:Gm1110	UTSW	9	26,800,977 (GRCm39)	missense	probably benign	0.00
R9758:Gm1110	UTSW	9	26,800,894 (GRCm39)	nonsense	probably null
RF002:Gm1110	UTSW	9	26,831,936 (GRCm39)	missense	probably damaging	1.00
X0063:Gm1110	UTSW	9	26,805,576 (GRCm39)	missense	probably benign	0.01
Z1088:Gm1110	UTSW	9	26,824,606 (GRCm39)	missense	probably benign	0.01

Posted On

2015-04-16