Incidental Mutation 'IGL02707:1700017B05Rik'
ID304382
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol 1700017B05Rik
Ensembl Gene ENSMUSG00000032300
Gene NameRIKEN cDNA 1700017B05 gene
SynonymsD9Ertd278e
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.220) question?
Stock #IGL02707
Quality Score
Status
Chromosome9
Chromosomal Location57253117-57262612 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 57258645 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Alanine at position 149 (T149A)
Ref Sequence ENSEMBL: ENSMUSP00000150884 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000034846] [ENSMUST00000213199] [ENSMUST00000215298] [ENSMUST00000217657]
Predicted Effect probably benign
Transcript: ENSMUST00000034846
AA Change: T149A

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000034846
Gene: ENSMUSG00000032300
AA Change: T149A

DomainStartEndE-ValueType
low complexity region 265 284 N/A INTRINSIC
low complexity region 293 299 N/A INTRINSIC
low complexity region 334 347 N/A INTRINSIC
low complexity region 649 675 N/A INTRINSIC
low complexity region 692 728 N/A INTRINSIC
low complexity region 785 799 N/A INTRINSIC
low complexity region 933 951 N/A INTRINSIC
low complexity region 963 977 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000213199
AA Change: T149A

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
Predicted Effect noncoding transcript
Transcript: ENSMUST00000214583
Predicted Effect probably benign
Transcript: ENSMUST00000215298
Predicted Effect noncoding transcript
Transcript: ENSMUST00000215426
Predicted Effect probably benign
Transcript: ENSMUST00000217657
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 55 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4932414N04Rik A C 2: 68,731,130 Q267P possibly damaging Het
Actr5 T C 2: 158,636,697 V489A probably benign Het
Adam26b T C 8: 43,519,858 probably benign Het
Aff4 A G 11: 53,399,740 N509S probably benign Het
Arhgap22 C T 14: 33,363,272 probably benign Het
Arhgap9 C A 10: 127,329,607 H628Q probably damaging Het
Asap1 A T 15: 64,129,274 I486N probably damaging Het
Asb15 A T 6: 24,558,788 probably benign Het
Avil A G 10: 127,006,562 D70G probably damaging Het
Cct6b T C 11: 82,754,954 probably benign Het
Cep63 A T 9: 102,586,981 I717K probably damaging Het
Chd4 G T 6: 125,108,767 A875S probably damaging Het
Col4a4 A T 1: 82,493,516 M706K unknown Het
Cr1l T C 1: 195,123,711 T155A probably benign Het
Ctnna3 A G 10: 63,504,065 N10S probably benign Het
Cubn A G 2: 13,446,032 V854A probably damaging Het
Dgkh T C 14: 78,585,651 T845A possibly damaging Het
F10 G A 8: 13,048,252 A152T probably damaging Het
Gabrg3 C A 7: 56,982,691 E170* probably null Het
Heatr5a A G 12: 51,921,366 V829A probably benign Het
Htt T A 5: 34,829,881 probably null Het
Icam4 T C 9: 21,030,474 Y257H possibly damaging Het
Jph1 A G 1: 17,004,451 S448P probably benign Het
Kansl1l G A 1: 66,773,445 L125F probably damaging Het
Kifc1 A T 17: 33,881,493 C46* probably null Het
Lce3b A G 3: 92,933,886 D96G unknown Het
Mab21l1 A T 3: 55,783,084 I31F possibly damaging Het
Mctp2 A G 7: 72,259,341 Y75H possibly damaging Het
Mesp2 A G 7: 79,811,526 I200V probably benign Het
Msr1 T C 8: 39,632,829 probably benign Het
Mtfr2 C T 10: 20,348,338 T6I probably benign Het
Myo5b T C 18: 74,695,367 probably benign Het
Myoc T A 1: 162,639,460 I66N probably benign Het
Olfr1242 A T 2: 89,493,827 Y162N probably damaging Het
Olfr1355 T C 10: 78,879,925 L251S probably damaging Het
Olfr149 T C 9: 39,702,641 I43V probably damaging Het
Olfr639 A C 7: 104,012,402 L100W probably damaging Het
Olfr659 T C 7: 104,670,929 C76R probably damaging Het
Olfr667 A G 7: 104,916,652 C215R probably damaging Het
Per2 T C 1: 91,450,728 D33G possibly damaging Het
Pknox1 A G 17: 31,602,819 I295V possibly damaging Het
Rgs11 G A 17: 26,207,631 V279I probably benign Het
Rhot2 A G 17: 25,844,296 S19P probably damaging Het
Rps6kb1 C A 11: 86,535,410 probably null Het
Serpinb1b C T 13: 33,091,665 T194I probably benign Het
Smarcad1 T A 6: 65,052,806 probably benign Het
Stxbp4 A G 11: 90,537,933 S449P probably benign Het
Thrb A C 14: 18,026,721 I275L probably benign Het
Tjp1 T A 7: 65,329,682 K365I possibly damaging Het
Tjp1 T A 7: 65,329,683 K365* probably null Het
Tm4sf4 C A 3: 57,426,518 C75* probably null Het
Tmem131 T C 1: 36,825,479 T558A probably benign Het
Txndc16 T C 14: 45,162,273 T408A probably benign Het
Ube2j1 T C 4: 33,038,206 L38P possibly damaging Het
Urb2 T C 8: 124,030,686 I1044T probably benign Het
Other mutations in 1700017B05Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01011:1700017B05Rik APN 9 57258246 missense probably damaging 1.00
IGL01287:1700017B05Rik APN 9 57257757 missense probably damaging 1.00
IGL01798:1700017B05Rik APN 9 57256638 missense probably benign 0.10
IGL01933:1700017B05Rik APN 9 57257367 missense possibly damaging 0.95
IGL02146:1700017B05Rik APN 9 57256740 missense possibly damaging 0.82
IGL02158:1700017B05Rik APN 9 57256619 unclassified probably null
IGL02277:1700017B05Rik APN 9 57258425 missense probably benign 0.05
IGL02887:1700017B05Rik APN 9 57258885 missense probably damaging 1.00
IGL02936:1700017B05Rik APN 9 57258404 missense possibly damaging 0.69
R0583:1700017B05Rik UTSW 9 57257643 missense probably benign 0.04
R0926:1700017B05Rik UTSW 9 57257549 missense probably damaging 0.99
R1812:1700017B05Rik UTSW 9 57257457 nonsense probably null
R1903:1700017B05Rik UTSW 9 57258352 missense possibly damaging 0.69
R4542:1700017B05Rik UTSW 9 57256592 missense probably damaging 1.00
R4596:1700017B05Rik UTSW 9 57257805 missense probably benign 0.03
R4631:1700017B05Rik UTSW 9 57257987 missense probably damaging 1.00
R4869:1700017B05Rik UTSW 9 57254205 missense probably damaging 1.00
R5265:1700017B05Rik UTSW 9 57258894 missense probably damaging 1.00
R5361:1700017B05Rik UTSW 9 57257185 missense probably damaging 1.00
R6216:1700017B05Rik UTSW 9 57257627 missense probably benign 0.33
R6356:1700017B05Rik UTSW 9 57254009 missense probably benign 0.11
R6579:1700017B05Rik UTSW 9 57254224 missense possibly damaging 0.89
R6774:1700017B05Rik UTSW 9 57256625 missense probably damaging 1.00
R6921:1700017B05Rik UTSW 9 57258736 missense probably damaging 1.00
R7089:1700017B05Rik UTSW 9 57258758 missense probably damaging 1.00
R7196:1700017B05Rik UTSW 9 57258222 frame shift probably null
R7197:1700017B05Rik UTSW 9 57258222 frame shift probably null
Posted On2015-04-16