Incidental Mutation 'R4613:Nlgn1'
| ID |
350939 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nlgn1
|
| Ensembl Gene |
ENSMUSG00000063887 |
| Gene Name |
neuroligin 1 |
| Synonyms |
NL1, Nlg1, 6330415N05Rik |
| MMRRC Submission |
041824-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4613 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
25480379-26386609 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 25490186 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 514
(T514A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142200
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000075054]
[ENSMUST00000108308]
[ENSMUST00000191835]
[ENSMUST00000193603]
|
| AlphaFold |
Q99K10 |
| PDB Structure |
Crystal structure of a synaptic adhesion complex [X-RAY DIFFRACTION]
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000075054
AA Change: T514A
PolyPhen 2
Score 0.010 (Sensitivity: 0.96; Specificity: 0.77)
|
| SMART Domains |
Protein: ENSMUSP00000074565
Gene: ENSMUSG00000063887
AA Change: T514A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:COesterase
|
29 |
626 |
4.8e-199 |
PFAM |
|
Pfam:Abhydrolase_3
|
196 |
302 |
2.2e-8 |
PFAM |
|
transmembrane domain
|
697 |
719 |
N/A |
INTRINSIC |
|
low complexity region
|
720 |
731 |
N/A |
INTRINSIC |
|
low complexity region
|
796 |
809 |
N/A |
INTRINSIC |
|
low complexity region
|
816 |
827 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
839 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108308
AA Change: T485A
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000103944
Gene: ENSMUSG00000063887
AA Change: T485A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:COesterase
|
29 |
597 |
2.5e-190 |
PFAM |
|
Pfam:Abhydrolase_3
|
176 |
306 |
4.3e-8 |
PFAM |
|
transmembrane domain
|
668 |
690 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
702 |
N/A |
INTRINSIC |
|
low complexity region
|
767 |
780 |
N/A |
INTRINSIC |
|
low complexity region
|
787 |
798 |
N/A |
INTRINSIC |
|
low complexity region
|
800 |
810 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000191835
AA Change: T485A
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000142086
Gene: ENSMUSG00000063887
AA Change: T485A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:COesterase
|
29 |
597 |
2.5e-190 |
PFAM |
|
Pfam:Abhydrolase_3
|
176 |
306 |
4.3e-8 |
PFAM |
|
transmembrane domain
|
668 |
690 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
702 |
N/A |
INTRINSIC |
|
low complexity region
|
767 |
780 |
N/A |
INTRINSIC |
|
low complexity region
|
787 |
798 |
N/A |
INTRINSIC |
|
low complexity region
|
800 |
810 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193603
AA Change: T514A
PolyPhen 2
Score 0.010 (Sensitivity: 0.96; Specificity: 0.77)
|
| SMART Domains |
Protein: ENSMUSP00000142200
Gene: ENSMUSG00000063887
AA Change: T514A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:COesterase
|
29 |
626 |
1.2e-186 |
PFAM |
|
Pfam:Abhydrolase_3
|
196 |
309 |
3.7e-8 |
PFAM |
|
transmembrane domain
|
697 |
719 |
N/A |
INTRINSIC |
|
low complexity region
|
720 |
731 |
N/A |
INTRINSIC |
|
low complexity region
|
796 |
809 |
N/A |
INTRINSIC |
|
low complexity region
|
816 |
827 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
839 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile but display impaired NMDA receptor-mediated synaptic transmission onto CA1 pyramidal cells. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(4) : Targeted(3) Gene trapped(1)
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9830107B12Rik |
A |
T |
17: 48,439,167 (GRCm39) |
L130I |
probably benign |
Het |
| Abca9 |
A |
G |
11: 110,035,610 (GRCm39) |
V670A |
probably benign |
Het |
| Adad1 |
A |
G |
3: 37,146,182 (GRCm39) |
N517D |
probably damaging |
Het |
| Ankle2 |
T |
C |
5: 110,379,245 (GRCm39) |
L48P |
probably benign |
Het |
| Aoc3 |
A |
T |
11: 101,228,485 (GRCm39) |
|
probably benign |
Het |
| Areg |
A |
G |
5: 91,291,363 (GRCm39) |
K102R |
probably benign |
Het |
| Bmp1 |
T |
C |
14: 70,745,963 (GRCm39) |
T167A |
probably damaging |
Het |
| C4b |
C |
T |
17: 34,953,525 (GRCm39) |
G986D |
probably benign |
Het |
| Caml |
G |
T |
13: 55,772,955 (GRCm39) |
G200C |
probably damaging |
Het |
| Ccdc40 |
A |
C |
11: 119,122,358 (GRCm39) |
R53S |
probably benign |
Het |
| Cdh22 |
T |
A |
2: 164,985,576 (GRCm39) |
I337L |
probably benign |
Het |
| Col12a1 |
A |
T |
9: 79,554,883 (GRCm39) |
V2065D |
probably benign |
Het |
| Copg2 |
A |
G |
6: 30,788,531 (GRCm39) |
S591P |
probably benign |
Het |
| Cyp2d34 |
G |
A |
15: 82,500,526 (GRCm39) |
P438S |
probably damaging |
Het |
| Dchs1 |
T |
C |
7: 105,421,931 (GRCm39) |
D163G |
probably damaging |
Het |
| Depdc1b |
T |
C |
13: 108,500,177 (GRCm39) |
V230A |
probably damaging |
Het |
| Depdc5 |
T |
A |
5: 33,132,790 (GRCm39) |
L1300H |
probably damaging |
Het |
| Dnah10 |
G |
T |
5: 124,839,933 (GRCm39) |
|
probably null |
Het |
| Dsc2 |
A |
T |
18: 20,174,876 (GRCm39) |
D466E |
probably damaging |
Het |
| Dthd1 |
A |
G |
5: 62,984,411 (GRCm39) |
D372G |
probably damaging |
Het |
| Eeig2 |
A |
T |
3: 108,934,571 (GRCm39) |
F23I |
probably benign |
Het |
| Eogt |
G |
T |
6: 97,111,265 (GRCm39) |
Q199K |
probably benign |
Het |
| Epha6 |
C |
A |
16: 59,486,960 (GRCm39) |
R1029L |
possibly damaging |
Het |
| Eppin |
C |
A |
2: 164,431,243 (GRCm39) |
E128* |
probably null |
Het |
| Fgf20 |
T |
C |
8: 40,739,652 (GRCm39) |
R33G |
probably benign |
Het |
| Fgg |
A |
G |
3: 82,917,397 (GRCm39) |
N142S |
probably damaging |
Het |
| Fhip2a |
C |
A |
19: 57,359,619 (GRCm39) |
P53Q |
probably damaging |
Het |
| Gba1 |
C |
T |
3: 89,115,951 (GRCm39) |
|
probably null |
Het |
| Gli2 |
A |
G |
1: 118,765,241 (GRCm39) |
V970A |
probably damaging |
Het |
| Gramd1b |
A |
T |
9: 40,219,289 (GRCm39) |
V508D |
probably damaging |
Het |
| Gucy2c |
T |
A |
6: 136,685,319 (GRCm39) |
D898V |
probably damaging |
Het |
| Kcnj15 |
T |
C |
16: 95,096,653 (GRCm39) |
Y92H |
probably damaging |
Het |
| L3mbtl3 |
A |
T |
10: 26,158,693 (GRCm39) |
S652T |
unknown |
Het |
| Ldb2 |
G |
T |
5: 44,633,893 (GRCm39) |
Q326K |
probably benign |
Het |
| Lipi |
C |
A |
16: 75,357,689 (GRCm39) |
R292L |
probably benign |
Het |
| Lrrc36 |
G |
A |
8: 106,176,246 (GRCm39) |
V207I |
possibly damaging |
Het |
| Lyplal1 |
C |
T |
1: 185,820,949 (GRCm39) |
G166D |
probably benign |
Het |
| Map1b |
A |
T |
13: 99,566,810 (GRCm39) |
Y1970* |
probably null |
Het |
| Map2 |
A |
G |
1: 66,464,628 (GRCm39) |
N287D |
probably damaging |
Het |
| Map3k11 |
G |
T |
19: 5,747,499 (GRCm39) |
Q578H |
probably damaging |
Het |
| Map3k11 |
A |
T |
19: 5,747,498 (GRCm39) |
Q578L |
probably benign |
Het |
| Map4k4 |
G |
A |
1: 40,056,351 (GRCm39) |
S1012N |
probably benign |
Het |
| Mapk13 |
A |
T |
17: 28,988,426 (GRCm39) |
N15Y |
probably damaging |
Het |
| Mapk15 |
G |
A |
15: 75,867,759 (GRCm39) |
A125T |
probably damaging |
Het |
| Mrgprb1 |
C |
A |
7: 48,097,456 (GRCm39) |
R152L |
possibly damaging |
Het |
| Mtrex |
C |
A |
13: 113,058,273 (GRCm39) |
E53* |
probably null |
Het |
| Muc5ac |
T |
G |
7: 141,344,840 (GRCm39) |
Y104D |
possibly damaging |
Het |
| Myo1h |
A |
G |
5: 114,486,440 (GRCm39) |
N566S |
possibly damaging |
Het |
| Myo1h |
C |
A |
5: 114,489,737 (GRCm39) |
H647Q |
probably benign |
Het |
| Neo1 |
A |
G |
9: 58,796,324 (GRCm39) |
I1201T |
possibly damaging |
Het |
| Or10al4 |
A |
G |
17: 38,037,587 (GRCm39) |
Y224C |
probably damaging |
Het |
| Or12j4 |
A |
T |
7: 140,046,981 (GRCm39) |
Y289F |
probably damaging |
Het |
| Or7a42 |
A |
G |
10: 78,791,899 (GRCm39) |
N287D |
probably damaging |
Het |
| Or8d4 |
T |
A |
9: 40,039,018 (GRCm39) |
K80* |
probably null |
Het |
| Orc2 |
A |
T |
1: 58,539,468 (GRCm39) |
L57* |
probably null |
Het |
| Otoa |
G |
A |
7: 120,744,791 (GRCm39) |
V850M |
probably damaging |
Het |
| Pcnx3 |
T |
C |
19: 5,717,247 (GRCm39) |
T1579A |
possibly damaging |
Het |
| Pde5a |
A |
T |
3: 122,616,742 (GRCm39) |
Y564F |
probably damaging |
Het |
| Pdxk |
A |
C |
10: 78,283,753 (GRCm39) |
I147S |
probably damaging |
Het |
| Pfdn5 |
A |
G |
15: 102,237,187 (GRCm39) |
D108G |
probably benign |
Het |
| Pink1 |
T |
C |
4: 138,044,621 (GRCm39) |
D342G |
probably damaging |
Het |
| Prkacb |
A |
T |
3: 146,443,753 (GRCm39) |
V336E |
probably damaging |
Het |
| Ptpro |
C |
A |
6: 137,393,834 (GRCm39) |
S13* |
probably null |
Het |
| Rfng |
A |
G |
11: 120,673,476 (GRCm39) |
L215P |
probably damaging |
Het |
| Rpn2 |
T |
C |
2: 157,144,345 (GRCm39) |
F336L |
possibly damaging |
Het |
| Sacs |
A |
G |
14: 61,449,246 (GRCm39) |
|
probably null |
Het |
| Sirpb1a |
T |
A |
3: 15,482,097 (GRCm39) |
Y77F |
probably benign |
Het |
| Slc30a8 |
A |
G |
15: 52,196,971 (GRCm39) |
D294G |
probably benign |
Het |
| Sox13 |
T |
C |
1: 133,316,672 (GRCm39) |
I212V |
probably benign |
Het |
| Srebf2 |
T |
A |
15: 82,069,549 (GRCm39) |
I657N |
possibly damaging |
Het |
| Srsf6 |
C |
A |
2: 162,775,629 (GRCm39) |
T146K |
probably benign |
Het |
| Strn4 |
T |
C |
7: 16,558,088 (GRCm39) |
V162A |
possibly damaging |
Het |
| Sulf2 |
T |
C |
2: 165,974,525 (GRCm39) |
D53G |
probably damaging |
Het |
| Tbc1d8 |
T |
A |
1: 39,411,789 (GRCm39) |
I1016F |
probably damaging |
Het |
| Tfrc |
G |
T |
16: 32,437,475 (GRCm39) |
A278S |
probably damaging |
Het |
| Tnrc6a |
T |
G |
7: 122,783,512 (GRCm39) |
|
probably null |
Het |
| Vmn1r83 |
T |
C |
7: 12,055,695 (GRCm39) |
I121V |
probably benign |
Het |
| Vps13d |
T |
C |
4: 144,858,225 (GRCm39) |
S2200G |
possibly damaging |
Het |
| Washc2 |
T |
A |
6: 116,206,230 (GRCm39) |
D397E |
probably damaging |
Het |
| Wipf3 |
T |
C |
6: 54,462,540 (GRCm39) |
L250P |
probably damaging |
Het |
| Xirp1 |
A |
G |
9: 119,848,748 (GRCm39) |
F45S |
probably damaging |
Het |
| Xpo5 |
A |
G |
17: 46,547,889 (GRCm39) |
T910A |
probably benign |
Het |
| Zfp235 |
T |
C |
7: 23,841,101 (GRCm39) |
Y507H |
probably damaging |
Het |
|
| Other mutations in Nlgn1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00510:Nlgn1
|
APN |
3 |
25,490,654 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL00543:Nlgn1
|
APN |
3 |
25,487,945 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00960:Nlgn1
|
APN |
3 |
25,966,861 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01533:Nlgn1
|
APN |
3 |
25,490,527 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL02146:Nlgn1
|
APN |
3 |
25,966,846 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02616:Nlgn1
|
APN |
3 |
25,488,409 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03342:Nlgn1
|
APN |
3 |
26,187,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
ligation
|
UTSW |
3 |
25,490,199 (GRCm39) |
nonsense |
probably null |
|
|
G1citation:Nlgn1
|
UTSW |
3 |
26,187,796 (GRCm39) |
missense |
probably benign |
0.00 |
|
P0018:Nlgn1
|
UTSW |
3 |
25,490,741 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0010:Nlgn1
|
UTSW |
3 |
25,490,006 (GRCm39) |
splice site |
probably benign |
|
|
R0010:Nlgn1
|
UTSW |
3 |
25,490,006 (GRCm39) |
splice site |
probably benign |
|
|
R0123:Nlgn1
|
UTSW |
3 |
25,490,089 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0134:Nlgn1
|
UTSW |
3 |
25,490,089 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0294:Nlgn1
|
UTSW |
3 |
26,187,625 (GRCm39) |
missense |
probably benign |
0.23 |
|
R0798:Nlgn1
|
UTSW |
3 |
25,488,410 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1051:Nlgn1
|
UTSW |
3 |
25,966,869 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1116:Nlgn1
|
UTSW |
3 |
25,488,038 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1289:Nlgn1
|
UTSW |
3 |
25,488,400 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1522:Nlgn1
|
UTSW |
3 |
25,490,073 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1550:Nlgn1
|
UTSW |
3 |
25,966,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1669:Nlgn1
|
UTSW |
3 |
25,490,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1853:Nlgn1
|
UTSW |
3 |
26,187,671 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1856:Nlgn1
|
UTSW |
3 |
25,494,201 (GRCm39) |
nonsense |
probably null |
|
|
R1935:Nlgn1
|
UTSW |
3 |
26,385,939 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R1936:Nlgn1
|
UTSW |
3 |
26,385,939 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R1952:Nlgn1
|
UTSW |
3 |
25,490,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1953:Nlgn1
|
UTSW |
3 |
25,490,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2004:Nlgn1
|
UTSW |
3 |
25,488,034 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2114:Nlgn1
|
UTSW |
3 |
26,187,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2116:Nlgn1
|
UTSW |
3 |
26,187,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2198:Nlgn1
|
UTSW |
3 |
25,487,925 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2994:Nlgn1
|
UTSW |
3 |
25,490,162 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3056:Nlgn1
|
UTSW |
3 |
25,487,860 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R4190:Nlgn1
|
UTSW |
3 |
25,488,062 (GRCm39) |
missense |
probably benign |
|
|
R4196:Nlgn1
|
UTSW |
3 |
25,488,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4654:Nlgn1
|
UTSW |
3 |
26,187,850 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4757:Nlgn1
|
UTSW |
3 |
25,490,507 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4757:Nlgn1
|
UTSW |
3 |
25,490,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4815:Nlgn1
|
UTSW |
3 |
25,490,194 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4884:Nlgn1
|
UTSW |
3 |
25,966,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4966:Nlgn1
|
UTSW |
3 |
25,974,401 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R5119:Nlgn1
|
UTSW |
3 |
25,487,958 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5842:Nlgn1
|
UTSW |
3 |
26,187,892 (GRCm39) |
splice site |
probably null |
|
|
R6218:Nlgn1
|
UTSW |
3 |
25,490,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6397:Nlgn1
|
UTSW |
3 |
25,487,827 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6500:Nlgn1
|
UTSW |
3 |
25,488,094 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6822:Nlgn1
|
UTSW |
3 |
26,187,796 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6846:Nlgn1
|
UTSW |
3 |
25,490,506 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7047:Nlgn1
|
UTSW |
3 |
25,490,199 (GRCm39) |
nonsense |
probably null |
|
|
R7147:Nlgn1
|
UTSW |
3 |
26,187,509 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7754:Nlgn1
|
UTSW |
3 |
25,488,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7886:Nlgn1
|
UTSW |
3 |
25,490,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8184:Nlgn1
|
UTSW |
3 |
25,490,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8261:Nlgn1
|
UTSW |
3 |
25,487,816 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8304:Nlgn1
|
UTSW |
3 |
26,187,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8364:Nlgn1
|
UTSW |
3 |
25,490,140 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8503:Nlgn1
|
UTSW |
3 |
26,187,522 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9035:Nlgn1
|
UTSW |
3 |
25,488,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9053:Nlgn1
|
UTSW |
3 |
25,488,607 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9209:Nlgn1
|
UTSW |
3 |
25,966,804 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9268:Nlgn1
|
UTSW |
3 |
25,490,548 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9368:Nlgn1
|
UTSW |
3 |
25,488,622 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9492:Nlgn1
|
UTSW |
3 |
25,488,480 (GRCm39) |
nonsense |
probably null |
|
|
R9596:Nlgn1
|
UTSW |
3 |
25,488,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9647:Nlgn1
|
UTSW |
3 |
25,488,182 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9697:Nlgn1
|
UTSW |
3 |
25,494,035 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
Z1176:Nlgn1
|
UTSW |
3 |
25,490,768 (GRCm39) |
missense |
probably benign |
0.12 |
|
| Predicted Primers |
PCR Primer
(F):5'- TAGGGCAGAGTACTTTCCTGAGG -3'
(R):5'- TATGGATATCCTGAAGGCAAAGATG -3'
Sequencing Primer
(F):5'- GCAGAGTACTTTCCTGAGGTACTTAC -3'
(R):5'- ACGGACCATCAATGGGTA -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation