Incidental Mutation 'R4966:Nlgn1'
| ID |
446658 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nlgn1
|
| Ensembl Gene |
ENSMUSG00000063887 |
| Gene Name |
neuroligin 1 |
| Synonyms |
NL1, Nlg1, 6330415N05Rik |
| MMRRC Submission |
042562-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4966 (G1)
|
| Quality Score |
180 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
25480379-26386609 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 25974401 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Aspartic acid
at position 165
(G165D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142200
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000075054]
[ENSMUST00000108308]
[ENSMUST00000191835]
[ENSMUST00000193603]
|
| AlphaFold |
Q99K10 |
| PDB Structure |
Crystal structure of a synaptic adhesion complex [X-RAY DIFFRACTION]
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000075054
AA Change: G165D
PolyPhen 2
Score 0.650 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000074565
Gene: ENSMUSG00000063887
AA Change: G165D
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:COesterase
|
29 |
626 |
4.8e-199 |
PFAM |
|
Pfam:Abhydrolase_3
|
196 |
302 |
2.2e-8 |
PFAM |
|
transmembrane domain
|
697 |
719 |
N/A |
INTRINSIC |
|
low complexity region
|
720 |
731 |
N/A |
INTRINSIC |
|
low complexity region
|
796 |
809 |
N/A |
INTRINSIC |
|
low complexity region
|
816 |
827 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
839 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108308
|
| SMART Domains |
Protein: ENSMUSP00000103944
Gene: ENSMUSG00000063887
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:COesterase
|
29 |
597 |
2.5e-190 |
PFAM |
|
Pfam:Abhydrolase_3
|
176 |
306 |
4.3e-8 |
PFAM |
|
transmembrane domain
|
668 |
690 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
702 |
N/A |
INTRINSIC |
|
low complexity region
|
767 |
780 |
N/A |
INTRINSIC |
|
low complexity region
|
787 |
798 |
N/A |
INTRINSIC |
|
low complexity region
|
800 |
810 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000191835
|
| SMART Domains |
Protein: ENSMUSP00000142086
Gene: ENSMUSG00000063887
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:COesterase
|
29 |
597 |
2.5e-190 |
PFAM |
|
Pfam:Abhydrolase_3
|
176 |
306 |
4.3e-8 |
PFAM |
|
transmembrane domain
|
668 |
690 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
702 |
N/A |
INTRINSIC |
|
low complexity region
|
767 |
780 |
N/A |
INTRINSIC |
|
low complexity region
|
787 |
798 |
N/A |
INTRINSIC |
|
low complexity region
|
800 |
810 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000193603
AA Change: G165D
PolyPhen 2
Score 0.650 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000142200
Gene: ENSMUSG00000063887
AA Change: G165D
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:COesterase
|
29 |
626 |
1.2e-186 |
PFAM |
|
Pfam:Abhydrolase_3
|
196 |
309 |
3.7e-8 |
PFAM |
|
transmembrane domain
|
697 |
719 |
N/A |
INTRINSIC |
|
low complexity region
|
720 |
731 |
N/A |
INTRINSIC |
|
low complexity region
|
796 |
809 |
N/A |
INTRINSIC |
|
low complexity region
|
816 |
827 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
839 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0954 |
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.2%
- 10x: 95.8%
- 20x: 90.6%
|
| Validation Efficiency |
96% (94/98) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile but display impaired NMDA receptor-mediated synaptic transmission onto CA1 pyramidal cells. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(4) : Targeted(3) Gene trapped(1)
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4833420G17Rik |
T |
C |
13: 119,610,757 (GRCm39) |
|
probably benign |
Het |
| 9030619P08Rik |
T |
A |
15: 75,303,267 (GRCm39) |
|
noncoding transcript |
Het |
| Abcb5 |
T |
A |
12: 118,850,626 (GRCm39) |
|
probably benign |
Het |
| Acox3 |
A |
G |
5: 35,747,080 (GRCm39) |
N166D |
probably damaging |
Het |
| Actn1 |
T |
C |
12: 80,219,904 (GRCm39) |
I656V |
probably benign |
Het |
| Arhgef15 |
A |
G |
11: 68,838,143 (GRCm39) |
V659A |
probably benign |
Het |
| AW551984 |
T |
C |
9: 39,508,472 (GRCm39) |
E348G |
possibly damaging |
Het |
| Bbs2 |
A |
T |
8: 94,807,435 (GRCm39) |
V453E |
probably damaging |
Het |
| Caskin1 |
A |
T |
17: 24,726,135 (GRCm39) |
D1414V |
probably damaging |
Het |
| Ccdc57 |
A |
T |
11: 120,751,978 (GRCm39) |
S868T |
probably benign |
Het |
| Cdc34b |
A |
T |
11: 94,633,087 (GRCm39) |
I96F |
probably damaging |
Het |
| Ctnnd1 |
A |
G |
2: 84,452,417 (GRCm39) |
F69L |
possibly damaging |
Het |
| Cyld |
A |
G |
8: 89,468,929 (GRCm39) |
I567V |
possibly damaging |
Het |
| Dact3 |
G |
C |
7: 16,620,013 (GRCm39) |
V503L |
unknown |
Het |
| Dlg1 |
C |
T |
16: 31,573,626 (GRCm39) |
T9I |
probably benign |
Het |
| Dnase1 |
T |
C |
16: 3,855,771 (GRCm39) |
|
probably benign |
Het |
| Drc7 |
G |
A |
8: 95,798,224 (GRCm39) |
E490K |
probably benign |
Het |
| Drd4 |
T |
C |
7: 140,873,690 (GRCm39) |
M114T |
probably damaging |
Het |
| Exoc3l4 |
A |
G |
12: 111,395,155 (GRCm39) |
H591R |
probably benign |
Het |
| Fgfr1 |
C |
A |
8: 26,062,461 (GRCm39) |
Y665* |
probably null |
Het |
| G2e3 |
A |
G |
12: 51,418,413 (GRCm39) |
I603V |
probably benign |
Het |
| Glp2r |
G |
T |
11: 67,648,419 (GRCm39) |
Y94* |
probably null |
Het |
| Gnat1 |
A |
T |
9: 107,554,433 (GRCm39) |
M115K |
probably benign |
Het |
| Gpr45 |
A |
G |
1: 43,072,280 (GRCm39) |
T308A |
probably benign |
Het |
| Grm1 |
T |
A |
10: 10,595,409 (GRCm39) |
K740* |
probably null |
Het |
| Gtsf2 |
T |
C |
15: 103,352,755 (GRCm39) |
E88G |
possibly damaging |
Het |
| Hsh2d |
C |
T |
8: 72,947,372 (GRCm39) |
A23V |
probably benign |
Het |
| Ino80c |
T |
C |
18: 24,239,702 (GRCm39) |
D153G |
probably damaging |
Het |
| Ints11 |
T |
C |
4: 155,971,385 (GRCm39) |
F278L |
probably damaging |
Het |
| Ints6 |
A |
G |
14: 62,939,911 (GRCm39) |
L593P |
probably damaging |
Het |
| Map4k1 |
A |
T |
7: 28,682,427 (GRCm39) |
H16L |
probably benign |
Het |
| Mipep |
G |
T |
14: 61,022,231 (GRCm39) |
R32L |
probably damaging |
Het |
| Mon1a |
A |
G |
9: 107,779,850 (GRCm39) |
E473G |
probably damaging |
Het |
| Myf5 |
A |
T |
10: 107,321,733 (GRCm39) |
C20* |
probably null |
Het |
| Myh11 |
T |
C |
16: 14,023,818 (GRCm39) |
E1512G |
probably damaging |
Het |
| Myo5c |
T |
C |
9: 75,176,878 (GRCm39) |
S608P |
probably benign |
Het |
| Myo9a |
A |
G |
9: 59,779,017 (GRCm39) |
D1591G |
probably benign |
Het |
| Myof |
T |
A |
19: 37,924,300 (GRCm39) |
I1306F |
probably damaging |
Het |
| Noc2l |
C |
G |
4: 156,330,368 (GRCm39) |
D513E |
probably damaging |
Het |
| Nup205 |
G |
A |
6: 35,220,784 (GRCm39) |
R1862H |
probably benign |
Het |
| Nup210l |
A |
G |
3: 90,014,208 (GRCm39) |
H65R |
probably benign |
Het |
| Or2y16 |
A |
G |
11: 49,334,945 (GRCm39) |
D89G |
possibly damaging |
Het |
| Or9k7 |
A |
T |
10: 130,046,306 (GRCm39) |
M231K |
probably benign |
Het |
| Pcmtd1 |
C |
A |
1: 7,231,233 (GRCm39) |
Y176* |
probably null |
Het |
| Pde6h |
C |
T |
6: 136,938,201 (GRCm39) |
T58I |
possibly damaging |
Het |
| Pkd1 |
T |
C |
17: 24,805,042 (GRCm39) |
|
probably null |
Het |
| Polr1e |
G |
A |
4: 45,029,429 (GRCm39) |
A297T |
probably damaging |
Het |
| Rbm34 |
T |
C |
8: 127,678,087 (GRCm39) |
D269G |
possibly damaging |
Het |
| Rdx |
T |
C |
9: 51,986,309 (GRCm39) |
V372A |
probably benign |
Het |
| Reep6 |
T |
A |
10: 80,169,633 (GRCm39) |
F107Y |
probably benign |
Het |
| Rere |
G |
T |
4: 150,698,273 (GRCm39) |
|
probably benign |
Het |
| Rmdn2 |
G |
T |
17: 79,974,304 (GRCm39) |
A266S |
probably damaging |
Het |
| Rnf32 |
G |
A |
5: 29,403,576 (GRCm39) |
R7H |
probably benign |
Het |
| Rnpepl1 |
A |
T |
1: 92,844,483 (GRCm39) |
N325I |
probably damaging |
Het |
| Rps6ka5 |
T |
A |
12: 100,519,325 (GRCm39) |
M763L |
probably benign |
Het |
| Ryr2 |
T |
C |
13: 11,729,497 (GRCm39) |
E2375G |
possibly damaging |
Het |
| Ryr2 |
T |
C |
13: 11,848,878 (GRCm39) |
T361A |
probably benign |
Het |
| Serpina3j |
T |
A |
12: 104,286,043 (GRCm39) |
C399* |
probably null |
Het |
| Serpinb9 |
T |
A |
13: 33,192,847 (GRCm39) |
W135R |
probably damaging |
Het |
| Sim2 |
T |
C |
16: 93,924,280 (GRCm39) |
V475A |
probably benign |
Het |
| Slc24a5 |
G |
A |
2: 124,910,188 (GRCm39) |
V30I |
probably benign |
Het |
| Snrnp25 |
A |
G |
11: 32,157,595 (GRCm39) |
K58E |
probably damaging |
Het |
| Stx1b |
T |
C |
7: 127,407,093 (GRCm39) |
I55V |
probably damaging |
Het |
| Tacc2 |
T |
C |
7: 130,330,507 (GRCm39) |
S264P |
probably damaging |
Het |
| Tbc1d4 |
A |
T |
14: 101,695,610 (GRCm39) |
Y943N |
probably damaging |
Het |
| Tlr5 |
T |
C |
1: 182,801,038 (GRCm39) |
I114T |
probably benign |
Het |
| Tm2d3 |
A |
G |
7: 65,347,469 (GRCm39) |
N101S |
possibly damaging |
Het |
| Tmem201 |
G |
T |
4: 149,803,144 (GRCm39) |
Q575K |
probably benign |
Het |
| Tmem241 |
A |
G |
18: 12,237,176 (GRCm39) |
S87P |
probably damaging |
Het |
| Trak2 |
G |
A |
1: 58,958,480 (GRCm39) |
T267I |
probably damaging |
Het |
| Trmt2a |
T |
A |
16: 18,067,418 (GRCm39) |
C30* |
probably null |
Het |
| Ttbk2 |
A |
T |
2: 120,603,758 (GRCm39) |
F258L |
possibly damaging |
Het |
| Ttk |
T |
A |
9: 83,747,201 (GRCm39) |
I680N |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,785,380 (GRCm39) |
D665G |
probably damaging |
Het |
| Tulp4 |
G |
A |
17: 6,249,088 (GRCm39) |
E36K |
probably damaging |
Het |
| Unc93b1 |
T |
C |
19: 3,992,023 (GRCm39) |
|
probably null |
Het |
| Uroc1 |
T |
C |
6: 90,322,376 (GRCm39) |
L300P |
probably damaging |
Het |
| Vmn2r67 |
A |
T |
7: 84,785,593 (GRCm39) |
V804E |
probably damaging |
Het |
| Wdr81 |
T |
A |
11: 75,336,775 (GRCm39) |
Q1538L |
probably benign |
Het |
| Zfp457 |
T |
A |
13: 67,441,342 (GRCm39) |
H315L |
probably damaging |
Het |
| Zfp518a |
T |
A |
19: 40,904,295 (GRCm39) |
V1408D |
possibly damaging |
Het |
| Zfp52 |
T |
G |
17: 21,780,665 (GRCm39) |
L171R |
probably benign |
Het |
| Zfp712 |
C |
T |
13: 67,188,676 (GRCm39) |
C617Y |
probably damaging |
Het |
| Zfp770 |
T |
C |
2: 114,027,868 (GRCm39) |
N67S |
probably benign |
Het |
| Zmat4 |
T |
C |
8: 24,392,085 (GRCm39) |
S83P |
probably damaging |
Het |
|
| Other mutations in Nlgn1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00510:Nlgn1
|
APN |
3 |
25,490,654 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL00543:Nlgn1
|
APN |
3 |
25,487,945 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00960:Nlgn1
|
APN |
3 |
25,966,861 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01533:Nlgn1
|
APN |
3 |
25,490,527 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL02146:Nlgn1
|
APN |
3 |
25,966,846 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02616:Nlgn1
|
APN |
3 |
25,488,409 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03342:Nlgn1
|
APN |
3 |
26,187,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
ligation
|
UTSW |
3 |
25,490,199 (GRCm39) |
nonsense |
probably null |
|
|
G1citation:Nlgn1
|
UTSW |
3 |
26,187,796 (GRCm39) |
missense |
probably benign |
0.00 |
|
P0018:Nlgn1
|
UTSW |
3 |
25,490,741 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0010:Nlgn1
|
UTSW |
3 |
25,490,006 (GRCm39) |
splice site |
probably benign |
|
|
R0010:Nlgn1
|
UTSW |
3 |
25,490,006 (GRCm39) |
splice site |
probably benign |
|
|
R0123:Nlgn1
|
UTSW |
3 |
25,490,089 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0134:Nlgn1
|
UTSW |
3 |
25,490,089 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0294:Nlgn1
|
UTSW |
3 |
26,187,625 (GRCm39) |
missense |
probably benign |
0.23 |
|
R0798:Nlgn1
|
UTSW |
3 |
25,488,410 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1051:Nlgn1
|
UTSW |
3 |
25,966,869 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1116:Nlgn1
|
UTSW |
3 |
25,488,038 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1289:Nlgn1
|
UTSW |
3 |
25,488,400 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1522:Nlgn1
|
UTSW |
3 |
25,490,073 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1550:Nlgn1
|
UTSW |
3 |
25,966,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1669:Nlgn1
|
UTSW |
3 |
25,490,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1853:Nlgn1
|
UTSW |
3 |
26,187,671 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1856:Nlgn1
|
UTSW |
3 |
25,494,201 (GRCm39) |
nonsense |
probably null |
|
|
R1935:Nlgn1
|
UTSW |
3 |
26,385,939 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R1936:Nlgn1
|
UTSW |
3 |
26,385,939 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R1952:Nlgn1
|
UTSW |
3 |
25,490,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1953:Nlgn1
|
UTSW |
3 |
25,490,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2004:Nlgn1
|
UTSW |
3 |
25,488,034 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2114:Nlgn1
|
UTSW |
3 |
26,187,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2116:Nlgn1
|
UTSW |
3 |
26,187,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2198:Nlgn1
|
UTSW |
3 |
25,487,925 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2994:Nlgn1
|
UTSW |
3 |
25,490,162 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3056:Nlgn1
|
UTSW |
3 |
25,487,860 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R4190:Nlgn1
|
UTSW |
3 |
25,488,062 (GRCm39) |
missense |
probably benign |
|
|
R4196:Nlgn1
|
UTSW |
3 |
25,488,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4613:Nlgn1
|
UTSW |
3 |
25,490,186 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4654:Nlgn1
|
UTSW |
3 |
26,187,850 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4757:Nlgn1
|
UTSW |
3 |
25,490,507 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4757:Nlgn1
|
UTSW |
3 |
25,490,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4815:Nlgn1
|
UTSW |
3 |
25,490,194 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4884:Nlgn1
|
UTSW |
3 |
25,966,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5119:Nlgn1
|
UTSW |
3 |
25,487,958 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5842:Nlgn1
|
UTSW |
3 |
26,187,892 (GRCm39) |
splice site |
probably null |
|
|
R6218:Nlgn1
|
UTSW |
3 |
25,490,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6397:Nlgn1
|
UTSW |
3 |
25,487,827 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6500:Nlgn1
|
UTSW |
3 |
25,488,094 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6822:Nlgn1
|
UTSW |
3 |
26,187,796 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6846:Nlgn1
|
UTSW |
3 |
25,490,506 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7047:Nlgn1
|
UTSW |
3 |
25,490,199 (GRCm39) |
nonsense |
probably null |
|
|
R7147:Nlgn1
|
UTSW |
3 |
26,187,509 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7754:Nlgn1
|
UTSW |
3 |
25,488,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7886:Nlgn1
|
UTSW |
3 |
25,490,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8184:Nlgn1
|
UTSW |
3 |
25,490,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8261:Nlgn1
|
UTSW |
3 |
25,487,816 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8304:Nlgn1
|
UTSW |
3 |
26,187,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8364:Nlgn1
|
UTSW |
3 |
25,490,140 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8503:Nlgn1
|
UTSW |
3 |
26,187,522 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9035:Nlgn1
|
UTSW |
3 |
25,488,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9053:Nlgn1
|
UTSW |
3 |
25,488,607 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9209:Nlgn1
|
UTSW |
3 |
25,966,804 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9268:Nlgn1
|
UTSW |
3 |
25,490,548 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9368:Nlgn1
|
UTSW |
3 |
25,488,622 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9492:Nlgn1
|
UTSW |
3 |
25,488,480 (GRCm39) |
nonsense |
probably null |
|
|
R9596:Nlgn1
|
UTSW |
3 |
25,488,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9647:Nlgn1
|
UTSW |
3 |
25,488,182 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9697:Nlgn1
|
UTSW |
3 |
25,494,035 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
Z1176:Nlgn1
|
UTSW |
3 |
25,490,768 (GRCm39) |
missense |
probably benign |
0.12 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAACATCTGAATGGTTGGCATC -3'
(R):5'- GGCCTCTGATTAAAAGACTAAACC -3'
Sequencing Primer
(F):5'- CATCTGAATGGTTGGCATCAAAATG -3'
(R):5'- CCTTGGGAATTTTAGTATTTACGT -3'
|
| Posted On |
2016-12-12 |
Incidental Mutation