Incidental Mutation 'R4783:Myh13'
| ID |
366738 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myh13
|
| Ensembl Gene |
ENSMUSG00000060180 |
| Gene Name |
myosin, heavy polypeptide 13, skeletal muscle |
| Synonyms |
EO Myosin, MyHC-eo, extraocular myosin |
| MMRRC Submission |
042416-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.157)
|
| Stock # |
R4783 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
67217929-67262413 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 67232096 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 459
(I459F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000137731
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000081911]
[ENSMUST00000108684]
[ENSMUST00000180845]
|
| AlphaFold |
B1AR69 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000081911
AA Change: I459F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000080584
Gene: ENSMUSG00000060180
AA Change: I459F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
74 |
8e-13 |
PFAM |
|
MYSc
|
80 |
783 |
N/A |
SMART |
|
IQ
|
784 |
806 |
4.6e-1 |
SMART |
|
Pfam:Myosin_tail_1
|
847 |
1928 |
4.6e-159 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000108684
AA Change: I459F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000104324
Gene: ENSMUSG00000060180
AA Change: I459F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
76 |
2.8e-14 |
PFAM |
|
MYSc
|
80 |
783 |
N/A |
SMART |
|
IQ
|
784 |
806 |
4.6e-1 |
SMART |
|
low complexity region
|
847 |
858 |
N/A |
INTRINSIC |
|
low complexity region
|
925 |
940 |
N/A |
INTRINSIC |
|
Pfam:Myosin_tail_1
|
1072 |
1930 |
N/A |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000180845
AA Change: I459F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000137731
Gene: ENSMUSG00000060180
AA Change: I459F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
76 |
2.8e-14 |
PFAM |
|
MYSc
|
80 |
783 |
N/A |
SMART |
|
IQ
|
784 |
806 |
4.6e-1 |
SMART |
|
low complexity region
|
847 |
858 |
N/A |
INTRINSIC |
|
low complexity region
|
925 |
940 |
N/A |
INTRINSIC |
|
Pfam:Myosin_tail_1
|
1072 |
1930 |
N/A |
PFAM |
|
| Meta Mutation Damage Score |
0.6953 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.6%
|
| Validation Efficiency |
100% (99/99) |
| Allele List at MGI |
All alleles(4) : Gene trapped(4) |
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3110082J24Rik |
G |
A |
5: 30,310,198 (GRCm39) |
R54* |
probably null |
Het |
| Acsl6 |
A |
T |
11: 54,227,819 (GRCm39) |
M350L |
probably damaging |
Het |
| Adgrv1 |
T |
C |
13: 81,243,564 (GRCm39) |
T6279A |
probably damaging |
Het |
| Ago3 |
A |
T |
4: 126,262,296 (GRCm39) |
M418K |
probably benign |
Het |
| Ascc2 |
G |
A |
11: 4,596,653 (GRCm39) |
R58H |
probably benign |
Het |
| Brinp3 |
A |
G |
1: 146,603,378 (GRCm39) |
|
probably benign |
Het |
| Carmil3 |
T |
C |
14: 55,738,778 (GRCm39) |
|
probably null |
Het |
| Ccdc47 |
T |
A |
11: 106,094,430 (GRCm39) |
H7L |
probably benign |
Het |
| Ccndbp1 |
A |
T |
2: 120,839,003 (GRCm39) |
T5S |
probably benign |
Het |
| Cdr2 |
A |
T |
7: 120,557,644 (GRCm39) |
F294I |
probably benign |
Het |
| Chd8 |
C |
A |
14: 52,442,825 (GRCm39) |
C575F |
probably damaging |
Het |
| Ctsll3 |
G |
A |
13: 60,948,209 (GRCm39) |
T156I |
probably damaging |
Het |
| Dgcr8 |
G |
A |
16: 18,076,174 (GRCm39) |
R4* |
probably null |
Het |
| Dnah1 |
T |
A |
14: 30,985,436 (GRCm39) |
K3818N |
probably damaging |
Het |
| Dok2 |
C |
T |
14: 71,015,314 (GRCm39) |
P347L |
probably benign |
Het |
| Elf1 |
T |
A |
14: 79,818,183 (GRCm39) |
N567K |
probably benign |
Het |
| Emsy |
T |
C |
7: 98,295,686 (GRCm39) |
N72S |
possibly damaging |
Het |
| Fam76a |
A |
G |
4: 132,643,501 (GRCm39) |
Y78H |
probably damaging |
Het |
| Fam76a |
A |
T |
4: 132,629,428 (GRCm39) |
|
probably null |
Het |
| Fbn1 |
A |
T |
2: 125,166,839 (GRCm39) |
C2026S |
probably damaging |
Het |
| Fbxo4 |
T |
C |
15: 3,998,523 (GRCm39) |
T312A |
probably benign |
Het |
| Fhip1a |
G |
T |
3: 85,595,877 (GRCm39) |
T115K |
probably damaging |
Het |
| Flnb |
A |
T |
14: 7,905,701 (GRCm38) |
E1150D |
probably benign |
Het |
| Galt |
T |
C |
4: 41,758,189 (GRCm39) |
V318A |
probably damaging |
Het |
| Git1 |
T |
G |
11: 77,390,663 (GRCm39) |
L133R |
probably damaging |
Het |
| Gm11168 |
G |
A |
9: 3,006,915 (GRCm39) |
M213I |
probably benign |
Het |
| Gm7233 |
A |
G |
14: 43,037,423 (GRCm39) |
E25G |
probably benign |
Het |
| Golga2 |
T |
A |
2: 32,187,168 (GRCm39) |
N89K |
probably damaging |
Het |
| Grin1 |
T |
A |
2: 25,182,393 (GRCm39) |
H956L |
possibly damaging |
Het |
| Hlcs |
C |
T |
16: 94,069,398 (GRCm39) |
V164I |
possibly damaging |
Het |
| Hmgcr |
G |
A |
13: 96,802,701 (GRCm39) |
T66M |
probably damaging |
Het |
| Ifi206 |
A |
T |
1: 173,308,432 (GRCm39) |
H521Q |
probably benign |
Het |
| Lgals3bp |
G |
A |
11: 118,284,340 (GRCm39) |
T413I |
probably damaging |
Het |
| Lrrc7 |
A |
G |
3: 157,832,850 (GRCm39) |
|
probably null |
Het |
| Mapk11 |
T |
C |
15: 89,033,691 (GRCm39) |
Y9C |
probably damaging |
Het |
| Mccc1 |
C |
A |
3: 36,030,022 (GRCm39) |
M429I |
probably damaging |
Het |
| Metrnl |
A |
G |
11: 121,598,750 (GRCm39) |
E40G |
probably benign |
Het |
| Mrgpra1 |
A |
G |
7: 46,985,218 (GRCm39) |
S154P |
probably damaging |
Het |
| Nalf1 |
T |
C |
8: 9,258,026 (GRCm39) |
Y374C |
probably damaging |
Het |
| Nedd4l |
C |
A |
18: 65,305,998 (GRCm39) |
D424E |
probably damaging |
Het |
| Nid1 |
C |
T |
13: 13,674,326 (GRCm39) |
R902W |
probably damaging |
Het |
| Nphp4 |
G |
A |
4: 152,639,003 (GRCm39) |
R878K |
probably benign |
Het |
| Numa1 |
A |
G |
7: 101,662,773 (GRCm39) |
T1997A |
probably damaging |
Het |
| Nutm1 |
G |
A |
2: 112,079,281 (GRCm39) |
A878V |
probably benign |
Het |
| Nxf1 |
G |
A |
19: 8,744,162 (GRCm39) |
A339T |
probably benign |
Het |
| Oas1b |
C |
A |
5: 120,952,578 (GRCm39) |
Q90K |
probably benign |
Het |
| Optn |
T |
C |
2: 5,059,438 (GRCm39) |
M27V |
probably benign |
Het |
| Or1r1 |
A |
G |
11: 73,874,834 (GRCm39) |
F200S |
probably damaging |
Het |
| Or2t35 |
A |
C |
14: 14,407,729 (GRCm38) |
Y167S |
possibly damaging |
Het |
| Or4f56 |
A |
T |
2: 111,703,395 (GRCm39) |
D268E |
possibly damaging |
Het |
| Or5ac17 |
G |
T |
16: 59,036,222 (GRCm39) |
F251L |
probably damaging |
Het |
| Or5d45 |
A |
G |
2: 88,153,500 (GRCm39) |
I183T |
probably damaging |
Het |
| Or5g29 |
A |
G |
2: 85,421,282 (GRCm39) |
T133A |
probably benign |
Het |
| Or5h18 |
G |
T |
16: 58,848,260 (GRCm39) |
D3E |
probably benign |
Het |
| Oxgr1 |
T |
C |
14: 120,259,776 (GRCm39) |
I144V |
probably benign |
Het |
| Pax5 |
T |
A |
4: 44,570,086 (GRCm39) |
T127S |
probably damaging |
Het |
| Pcsk2 |
T |
C |
2: 143,529,599 (GRCm39) |
|
probably null |
Het |
| Pdxk |
A |
G |
10: 78,300,626 (GRCm39) |
V19A |
possibly damaging |
Het |
| Pik3c2a |
A |
T |
7: 116,017,060 (GRCm39) |
S232R |
probably damaging |
Het |
| Ppip5k1 |
T |
C |
2: 121,171,329 (GRCm39) |
D620G |
possibly damaging |
Het |
| Ppp4r4 |
T |
A |
12: 103,557,117 (GRCm39) |
|
probably null |
Het |
| Psmd1 |
A |
G |
1: 86,006,434 (GRCm39) |
N267D |
probably damaging |
Het |
| Pudp |
A |
G |
18: 50,701,136 (GRCm39) |
V199A |
probably damaging |
Het |
| Rasal3 |
T |
A |
17: 32,615,755 (GRCm39) |
D361V |
probably damaging |
Het |
| Rbm12 |
T |
C |
2: 155,938,484 (GRCm39) |
D596G |
possibly damaging |
Het |
| Rbm6 |
T |
C |
9: 107,730,102 (GRCm39) |
D182G |
probably damaging |
Het |
| Rif1 |
T |
C |
2: 52,002,759 (GRCm39) |
V2071A |
probably damaging |
Het |
| Rilp |
C |
T |
11: 75,401,467 (GRCm39) |
A110V |
possibly damaging |
Het |
| Rprd2 |
A |
G |
3: 95,681,645 (GRCm39) |
V332A |
probably benign |
Het |
| Sbpl |
T |
A |
17: 24,172,304 (GRCm39) |
D205V |
unknown |
Het |
| Scn9a |
T |
C |
2: 66,370,967 (GRCm39) |
I538V |
probably benign |
Het |
| Serpina1d |
T |
C |
12: 103,734,083 (GRCm39) |
S74G |
possibly damaging |
Het |
| Serpina3n |
T |
C |
12: 104,375,369 (GRCm39) |
I147T |
possibly damaging |
Het |
| Serpinb8 |
A |
G |
1: 107,532,472 (GRCm39) |
N188S |
probably benign |
Het |
| Sipa1l3 |
A |
G |
7: 29,077,066 (GRCm39) |
V902A |
probably damaging |
Het |
| Slc25a47 |
T |
A |
12: 108,821,260 (GRCm39) |
L123Q |
probably damaging |
Het |
| Slc30a2 |
A |
T |
4: 134,071,317 (GRCm39) |
|
probably null |
Het |
| Slc66a1 |
G |
T |
4: 139,027,312 (GRCm39) |
H343Q |
probably benign |
Het |
| Snx13 |
T |
A |
12: 35,148,285 (GRCm39) |
D271E |
probably damaging |
Het |
| Tbc1d9b |
A |
G |
11: 50,062,125 (GRCm39) |
N1211S |
probably benign |
Het |
| Tdrd3 |
T |
A |
14: 87,709,537 (GRCm39) |
I67N |
probably damaging |
Het |
| Thbs1 |
T |
C |
2: 117,945,273 (GRCm39) |
V282A |
probably benign |
Het |
| Tmc8 |
A |
G |
11: 117,682,431 (GRCm39) |
|
probably null |
Het |
| Trim11 |
T |
A |
11: 58,879,750 (GRCm39) |
F284Y |
probably null |
Het |
| Ttn |
G |
T |
2: 76,552,141 (GRCm39) |
Y29419* |
probably null |
Het |
| Ttn |
A |
G |
2: 76,599,947 (GRCm39) |
Y19076H |
probably damaging |
Het |
| Ubr4 |
T |
C |
4: 139,149,044 (GRCm39) |
S448P |
possibly damaging |
Het |
| Ugt2b34 |
T |
C |
5: 87,039,332 (GRCm39) |
E443G |
probably damaging |
Het |
| Usp29 |
A |
G |
7: 6,964,390 (GRCm39) |
T78A |
probably damaging |
Het |
| Vmn1r227 |
A |
G |
17: 20,955,396 (GRCm39) |
|
noncoding transcript |
Het |
| Vmn1r85 |
A |
T |
7: 12,818,788 (GRCm39) |
W119R |
probably damaging |
Het |
| Vmn2r12 |
A |
T |
5: 109,234,379 (GRCm39) |
V611E |
probably damaging |
Het |
| Vmn2r97 |
A |
T |
17: 19,149,550 (GRCm39) |
M313L |
probably benign |
Het |
| Zap70 |
T |
C |
1: 36,818,254 (GRCm39) |
Y314H |
probably damaging |
Het |
| Zfp667 |
T |
A |
7: 6,308,684 (GRCm39) |
F451I |
possibly damaging |
Het |
|
| Other mutations in Myh13 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00497:Myh13
|
APN |
11 |
67,233,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00808:Myh13
|
APN |
11 |
67,225,830 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00822:Myh13
|
APN |
11 |
67,252,154 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL00823:Myh13
|
APN |
11 |
67,246,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00945:Myh13
|
APN |
11 |
67,238,832 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL01414:Myh13
|
APN |
11 |
67,233,298 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01482:Myh13
|
APN |
11 |
67,242,894 (GRCm39) |
missense |
probably benign |
|
|
IGL01523:Myh13
|
APN |
11 |
67,238,769 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL01723:Myh13
|
APN |
11 |
67,260,045 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01997:Myh13
|
APN |
11 |
67,257,992 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02369:Myh13
|
APN |
11 |
67,251,100 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02478:Myh13
|
APN |
11 |
67,260,204 (GRCm39) |
missense |
probably benign |
|
|
IGL02663:Myh13
|
APN |
11 |
67,245,753 (GRCm39) |
nonsense |
probably null |
|
|
IGL02851:Myh13
|
APN |
11 |
67,239,742 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02863:Myh13
|
APN |
11 |
67,223,367 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02929:Myh13
|
APN |
11 |
67,257,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02979:Myh13
|
APN |
11 |
67,225,788 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL03065:Myh13
|
APN |
11 |
67,235,679 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03214:Myh13
|
APN |
11 |
67,244,411 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL03223:Myh13
|
APN |
11 |
67,241,068 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL03231:Myh13
|
APN |
11 |
67,242,817 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03407:Myh13
|
APN |
11 |
67,242,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
3-1:Myh13
|
UTSW |
11 |
67,242,777 (GRCm39) |
splice site |
probably benign |
|
|
P0042:Myh13
|
UTSW |
11 |
67,225,817 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0047:Myh13
|
UTSW |
11 |
67,258,063 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0047:Myh13
|
UTSW |
11 |
67,258,063 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0379:Myh13
|
UTSW |
11 |
67,260,121 (GRCm39) |
unclassified |
probably benign |
|
|
R0496:Myh13
|
UTSW |
11 |
67,239,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0584:Myh13
|
UTSW |
11 |
67,251,200 (GRCm39) |
nonsense |
probably null |
|
|
R0595:Myh13
|
UTSW |
11 |
67,235,672 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0621:Myh13
|
UTSW |
11 |
67,232,058 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0834:Myh13
|
UTSW |
11 |
67,240,436 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R0893:Myh13
|
UTSW |
11 |
67,225,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0964:Myh13
|
UTSW |
11 |
67,235,828 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0973:Myh13
|
UTSW |
11 |
67,223,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Myh13
|
UTSW |
11 |
67,223,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0974:Myh13
|
UTSW |
11 |
67,223,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1028:Myh13
|
UTSW |
11 |
67,247,007 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R1112:Myh13
|
UTSW |
11 |
67,245,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1283:Myh13
|
UTSW |
11 |
67,261,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1288:Myh13
|
UTSW |
11 |
67,244,544 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1386:Myh13
|
UTSW |
11 |
67,261,776 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1457:Myh13
|
UTSW |
11 |
67,221,872 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1503:Myh13
|
UTSW |
11 |
67,244,500 (GRCm39) |
missense |
probably benign |
0.43 |
|
R1574:Myh13
|
UTSW |
11 |
67,253,407 (GRCm39) |
unclassified |
probably benign |
|
|
R1673:Myh13
|
UTSW |
11 |
67,242,945 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1693:Myh13
|
UTSW |
11 |
67,232,310 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1763:Myh13
|
UTSW |
11 |
67,225,402 (GRCm39) |
missense |
probably benign |
|
|
R2029:Myh13
|
UTSW |
11 |
67,252,115 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2030:Myh13
|
UTSW |
11 |
67,241,064 (GRCm39) |
missense |
probably benign |
|
|
R2247:Myh13
|
UTSW |
11 |
67,225,384 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2393:Myh13
|
UTSW |
11 |
67,231,184 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2395:Myh13
|
UTSW |
11 |
67,255,748 (GRCm39) |
missense |
probably benign |
0.12 |
|
R2884:Myh13
|
UTSW |
11 |
67,228,469 (GRCm39) |
missense |
probably benign |
0.27 |
|
R3696:Myh13
|
UTSW |
11 |
67,235,870 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R3786:Myh13
|
UTSW |
11 |
67,218,014 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3875:Myh13
|
UTSW |
11 |
67,249,020 (GRCm39) |
missense |
probably benign |
0.26 |
|
R3918:Myh13
|
UTSW |
11 |
67,220,064 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4061:Myh13
|
UTSW |
11 |
67,221,715 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4160:Myh13
|
UTSW |
11 |
67,255,636 (GRCm39) |
intron |
probably benign |
|
|
R4183:Myh13
|
UTSW |
11 |
67,240,436 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4392:Myh13
|
UTSW |
11 |
67,235,707 (GRCm39) |
splice site |
probably null |
|
|
R4639:Myh13
|
UTSW |
11 |
67,232,377 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4670:Myh13
|
UTSW |
11 |
67,255,564 (GRCm39) |
nonsense |
probably null |
|
|
R4877:Myh13
|
UTSW |
11 |
67,228,477 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5250:Myh13
|
UTSW |
11 |
67,218,085 (GRCm39) |
nonsense |
probably null |
|
|
R5278:Myh13
|
UTSW |
11 |
67,225,390 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5371:Myh13
|
UTSW |
11 |
67,235,616 (GRCm39) |
splice site |
probably null |
|
|
R5479:Myh13
|
UTSW |
11 |
67,239,648 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5510:Myh13
|
UTSW |
11 |
67,228,549 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5690:Myh13
|
UTSW |
11 |
67,220,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5797:Myh13
|
UTSW |
11 |
67,225,828 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5823:Myh13
|
UTSW |
11 |
67,251,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5877:Myh13
|
UTSW |
11 |
67,244,484 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R6041:Myh13
|
UTSW |
11 |
67,255,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Myh13
|
UTSW |
11 |
67,245,588 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6244:Myh13
|
UTSW |
11 |
67,253,327 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6454:Myh13
|
UTSW |
11 |
67,241,191 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6617:Myh13
|
UTSW |
11 |
67,252,226 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6707:Myh13
|
UTSW |
11 |
67,241,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6747:Myh13
|
UTSW |
11 |
67,241,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6823:Myh13
|
UTSW |
11 |
67,246,984 (GRCm39) |
missense |
probably benign |
|
|
R6911:Myh13
|
UTSW |
11 |
67,245,753 (GRCm39) |
nonsense |
probably null |
|
|
R6997:Myh13
|
UTSW |
11 |
67,217,980 (GRCm39) |
nonsense |
probably null |
|
|
R7033:Myh13
|
UTSW |
11 |
67,260,142 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7145:Myh13
|
UTSW |
11 |
67,245,566 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7232:Myh13
|
UTSW |
11 |
67,239,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7428:Myh13
|
UTSW |
11 |
67,223,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7448:Myh13
|
UTSW |
11 |
67,255,286 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7474:Myh13
|
UTSW |
11 |
67,258,537 (GRCm39) |
missense |
|
|
|
R7474:Myh13
|
UTSW |
11 |
67,217,990 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7766:Myh13
|
UTSW |
11 |
67,249,155 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7809:Myh13
|
UTSW |
11 |
67,241,167 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7813:Myh13
|
UTSW |
11 |
67,218,056 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7953:Myh13
|
UTSW |
11 |
67,231,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8085:Myh13
|
UTSW |
11 |
67,225,613 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8397:Myh13
|
UTSW |
11 |
67,241,113 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R8434:Myh13
|
UTSW |
11 |
67,254,011 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8490:Myh13
|
UTSW |
11 |
67,255,351 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8676:Myh13
|
UTSW |
11 |
67,233,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8681:Myh13
|
UTSW |
11 |
67,242,960 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8777:Myh13
|
UTSW |
11 |
67,252,161 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8777-TAIL:Myh13
|
UTSW |
11 |
67,252,161 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8965:Myh13
|
UTSW |
11 |
67,255,432 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9088:Myh13
|
UTSW |
11 |
67,242,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9151:Myh13
|
UTSW |
11 |
67,252,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9154:Myh13
|
UTSW |
11 |
67,253,318 (GRCm39) |
missense |
probably benign |
|
|
R9182:Myh13
|
UTSW |
11 |
67,228,579 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9332:Myh13
|
UTSW |
11 |
67,254,109 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R9393:Myh13
|
UTSW |
11 |
67,242,894 (GRCm39) |
missense |
probably benign |
|
|
R9446:Myh13
|
UTSW |
11 |
67,255,325 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9474:Myh13
|
UTSW |
11 |
67,255,712 (GRCm39) |
missense |
|
|
|
R9690:Myh13
|
UTSW |
11 |
67,249,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9761:Myh13
|
UTSW |
11 |
67,251,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9778:Myh13
|
UTSW |
11 |
67,249,016 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Myh13
|
UTSW |
11 |
67,220,121 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Myh13
|
UTSW |
11 |
67,255,417 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Myh13
|
UTSW |
11 |
67,241,278 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGCAACACTCAATTACTTTTGACC -3'
(R):5'- AAGTTGATGCACAGCTGCTC -3'
Sequencing Primer
(F):5'- GACCATCATGATGTCAATTTGATGC -3'
(R):5'- TGCTCCAGGCTGTTGAAC -3'
|
| Posted On |
2015-12-29 |
Incidental Mutation