Incidental Mutation 'R4842:Myh9'
| ID |
371950 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myh9
|
| Ensembl Gene |
ENSMUSG00000022443 |
| Gene Name |
myosin, heavy polypeptide 9, non-muscle |
| Synonyms |
Myhn-1, myosin IIA, Fltn, Myhn1, D0Jmb2, E030044M24Rik, NMHC II-A |
| MMRRC Submission |
042455-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4842 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
77644787-77726375 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 77653453 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 1348
(E1348G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000016771
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000016771]
[ENSMUST00000231192]
|
| AlphaFold |
Q8VDD5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000016771
AA Change: E1348G
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000016771
Gene: ENSMUSG00000022443
AA Change: E1348G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
29 |
69 |
3.4e-11 |
PFAM |
|
MYSc
|
75 |
777 |
N/A |
SMART |
|
IQ
|
778 |
800 |
1.46e-3 |
SMART |
|
Pfam:Myosin_tail_1
|
841 |
1921 |
N/A |
PFAM |
|
low complexity region
|
1948 |
1959 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139729
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000229259
AA Change: E73G
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000231192
|
| Meta Mutation Damage Score |
0.6702 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.7%
- 20x: 93.6%
|
| Validation Efficiency |
95% (107/113) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011]
PHENOTYPE: Homozygous null mice display embryonic lethality. Heterozygous null mice display hearing loss with incomplete penetrance. Mice homozygous or heterozygous for one of several knock-in alleles exhibit macrothrombocytopenia, nephritis, cataracts and deafness. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 99 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1600012H06Rik |
A |
T |
17: 15,164,001 (GRCm39) |
I43L |
possibly damaging |
Het |
| 4930449A18Rik |
T |
A |
3: 59,749,153 (GRCm39) |
|
noncoding transcript |
Het |
| Abcc8 |
T |
C |
7: 45,800,252 (GRCm39) |
K510R |
probably damaging |
Het |
| Adamtsl3 |
C |
T |
7: 82,178,069 (GRCm39) |
R511C |
probably damaging |
Het |
| Arhgap11a |
T |
C |
2: 113,670,107 (GRCm39) |
S339G |
probably damaging |
Het |
| C2cd3 |
A |
G |
7: 100,065,397 (GRCm39) |
T728A |
probably benign |
Het |
| Cand1 |
C |
A |
10: 119,049,451 (GRCm39) |
|
probably null |
Het |
| Catspere1 |
A |
T |
1: 177,699,624 (GRCm39) |
|
noncoding transcript |
Het |
| Ccdc121rt2 |
A |
T |
5: 112,598,106 (GRCm39) |
K218* |
probably null |
Het |
| Cd209c |
G |
T |
8: 3,995,905 (GRCm39) |
R2S |
probably benign |
Het |
| Cdc16 |
A |
G |
8: 13,831,644 (GRCm39) |
|
probably benign |
Het |
| Ces1g |
C |
T |
8: 94,060,323 (GRCm39) |
E99K |
probably benign |
Het |
| Chrna7 |
A |
C |
7: 62,862,196 (GRCm39) |
L10R |
probably benign |
Het |
| Clnk |
C |
T |
5: 38,870,412 (GRCm39) |
|
probably null |
Het |
| Cntrob |
C |
G |
11: 69,206,220 (GRCm39) |
L315F |
possibly damaging |
Het |
| Ctdp1 |
A |
G |
18: 80,451,941 (GRCm39) |
S145P |
unknown |
Het |
| Dennd2a |
T |
C |
6: 39,474,044 (GRCm39) |
D430G |
probably damaging |
Het |
| Dnajc16 |
A |
G |
4: 141,501,936 (GRCm39) |
F298S |
probably damaging |
Het |
| Dock5 |
T |
C |
14: 68,055,012 (GRCm39) |
D618G |
probably damaging |
Het |
| Drc3 |
G |
A |
11: 60,261,361 (GRCm39) |
A171T |
probably benign |
Het |
| Ecel1 |
A |
T |
1: 87,081,023 (GRCm39) |
N322K |
probably damaging |
Het |
| Eftud2 |
A |
G |
11: 102,745,640 (GRCm39) |
F362L |
probably damaging |
Het |
| Egfr |
C |
T |
11: 16,861,607 (GRCm39) |
H1129Y |
probably benign |
Het |
| Eif2b1 |
A |
G |
5: 124,714,971 (GRCm39) |
S102P |
probably damaging |
Het |
| Erich3 |
T |
A |
3: 154,410,480 (GRCm39) |
F112I |
possibly damaging |
Het |
| Fam107b |
T |
C |
2: 3,779,580 (GRCm39) |
L261S |
probably damaging |
Het |
| Fat3 |
A |
C |
9: 15,908,883 (GRCm39) |
V2373G |
probably damaging |
Het |
| Fcgbpl1 |
T |
A |
7: 27,850,147 (GRCm39) |
C1198S |
probably damaging |
Het |
| Gadd45a |
A |
T |
6: 67,013,873 (GRCm39) |
L58Q |
probably damaging |
Het |
| Gask1b |
G |
A |
3: 79,843,912 (GRCm39) |
R377H |
probably damaging |
Het |
| Gipr |
C |
T |
7: 18,896,601 (GRCm39) |
R165H |
probably damaging |
Het |
| Gje1 |
C |
T |
10: 14,593,082 (GRCm39) |
G45R |
probably null |
Het |
| Gldc |
T |
A |
19: 30,111,132 (GRCm39) |
N548I |
possibly damaging |
Het |
| Gm13035 |
A |
G |
4: 146,009,993 (GRCm39) |
|
noncoding transcript |
Het |
| Gm27013 |
T |
A |
6: 130,497,700 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5436 |
A |
T |
12: 84,305,584 (GRCm39) |
|
noncoding transcript |
Het |
| Grik3 |
C |
A |
4: 125,584,969 (GRCm39) |
N612K |
probably damaging |
Het |
| H2bc13 |
C |
T |
13: 21,900,234 (GRCm39) |
|
probably benign |
Het |
| Hfm1 |
C |
A |
5: 107,040,617 (GRCm39) |
W716L |
probably damaging |
Het |
| Il5ra |
T |
C |
6: 106,715,336 (GRCm39) |
Y166C |
probably damaging |
Het |
| Iqcb1 |
A |
G |
16: 36,655,952 (GRCm39) |
E113G |
probably benign |
Het |
| Kcnk10 |
A |
T |
12: 98,401,175 (GRCm39) |
M486K |
probably benign |
Het |
| Kcnv2 |
A |
G |
19: 27,301,190 (GRCm39) |
D347G |
probably damaging |
Het |
| Kif21b |
C |
A |
1: 136,072,958 (GRCm39) |
H119N |
probably damaging |
Het |
| Lamb1 |
C |
T |
12: 31,337,432 (GRCm39) |
H388Y |
probably damaging |
Het |
| Leng9 |
T |
C |
7: 4,152,385 (GRCm39) |
D97G |
probably damaging |
Het |
| Lmbr1 |
G |
A |
5: 29,492,424 (GRCm39) |
T55I |
probably damaging |
Het |
| Lrp1 |
G |
T |
10: 127,419,805 (GRCm39) |
R935S |
probably damaging |
Het |
| Lrp2 |
A |
T |
2: 69,299,755 (GRCm39) |
V3099E |
probably benign |
Het |
| Lrrcc1 |
C |
A |
3: 14,627,571 (GRCm39) |
D503E |
probably benign |
Het |
| Map1a |
T |
A |
2: 121,132,567 (GRCm39) |
S890T |
probably damaging |
Het |
| Msh2 |
C |
A |
17: 88,030,841 (GRCm39) |
A906E |
probably benign |
Het |
| Mybph |
A |
T |
1: 134,126,233 (GRCm39) |
E349V |
probably damaging |
Het |
| Myh7b |
C |
A |
2: 155,475,909 (GRCm39) |
L1935M |
probably benign |
Het |
| Myzap |
A |
G |
9: 71,456,037 (GRCm39) |
S328P |
probably damaging |
Het |
| Nbeal1 |
T |
C |
1: 60,292,534 (GRCm39) |
L1062P |
probably damaging |
Het |
| Nepro |
G |
A |
16: 44,555,160 (GRCm39) |
S412N |
probably null |
Het |
| Nr1h3 |
A |
G |
2: 91,020,563 (GRCm39) |
F257L |
probably benign |
Het |
| Nudt5 |
T |
C |
2: 5,869,239 (GRCm39) |
V155A |
probably benign |
Het |
| Ofcc1 |
G |
A |
13: 40,168,864 (GRCm39) |
T841I |
probably damaging |
Het |
| Or13a25 |
A |
T |
7: 140,247,502 (GRCm39) |
I94F |
probably damaging |
Het |
| Or52d3 |
A |
T |
7: 104,229,422 (GRCm39) |
I190L |
probably benign |
Het |
| Or6ae1 |
A |
G |
7: 139,742,602 (GRCm39) |
L87P |
possibly damaging |
Het |
| Pde1a |
T |
A |
2: 79,959,181 (GRCm39) |
|
probably benign |
Het |
| Pde4dip |
T |
A |
3: 97,700,844 (GRCm39) |
H220L |
probably damaging |
Het |
| Pde9a |
T |
A |
17: 31,662,135 (GRCm39) |
|
probably null |
Het |
| Pnkp |
C |
A |
7: 44,511,070 (GRCm39) |
|
probably null |
Het |
| Pnpla7 |
A |
G |
2: 24,870,064 (GRCm39) |
T15A |
probably benign |
Het |
| Polq |
G |
T |
16: 36,869,145 (GRCm39) |
|
probably null |
Het |
| Ppfia2 |
C |
T |
10: 106,690,818 (GRCm39) |
T553I |
probably benign |
Het |
| Ptk6 |
T |
G |
2: 180,838,784 (GRCm39) |
N323T |
possibly damaging |
Het |
| Rhox3c |
G |
A |
X: 36,652,077 (GRCm39) |
A60T |
probably damaging |
Het |
| Rnf4 |
T |
A |
5: 34,506,053 (GRCm39) |
V61E |
probably damaging |
Het |
| Rnf5 |
A |
G |
17: 34,820,977 (GRCm39) |
|
probably benign |
Het |
| Sardh |
A |
G |
2: 27,081,967 (GRCm39) |
V853A |
probably benign |
Het |
| Scfd1 |
T |
C |
12: 51,436,109 (GRCm39) |
V86A |
probably damaging |
Het |
| Scube3 |
G |
A |
17: 28,383,097 (GRCm39) |
C425Y |
probably damaging |
Het |
| Sema5a |
C |
T |
15: 32,609,563 (GRCm39) |
H490Y |
probably benign |
Het |
| Sfta2 |
T |
C |
17: 35,960,773 (GRCm39) |
|
probably benign |
Het |
| Sh3d19 |
T |
C |
3: 86,031,049 (GRCm39) |
Y738H |
probably damaging |
Het |
| Shc2 |
T |
C |
10: 79,458,295 (GRCm39) |
R463G |
probably damaging |
Het |
| Socs7 |
T |
A |
11: 97,267,829 (GRCm39) |
I320N |
possibly damaging |
Het |
| Speer2 |
A |
T |
16: 69,654,988 (GRCm39) |
M159K |
probably benign |
Het |
| Sppl2c |
A |
C |
11: 104,078,478 (GRCm39) |
H426P |
probably benign |
Het |
| Stag3 |
T |
G |
5: 138,307,627 (GRCm39) |
|
probably null |
Het |
| Stxbp5 |
C |
A |
10: 9,638,635 (GRCm39) |
V1055L |
probably benign |
Het |
| Synpo |
A |
T |
18: 60,736,684 (GRCm39) |
S421T |
probably damaging |
Het |
| Taf6l |
A |
G |
19: 8,759,770 (GRCm39) |
V135A |
possibly damaging |
Het |
| Tas2r116 |
G |
A |
6: 132,832,660 (GRCm39) |
S87N |
probably benign |
Het |
| Tomm6 |
T |
C |
17: 47,998,994 (GRCm39) |
|
probably benign |
Het |
| Trabd |
T |
C |
15: 88,966,915 (GRCm39) |
M113T |
probably benign |
Het |
| Trim58 |
G |
A |
11: 58,542,150 (GRCm39) |
G370E |
probably damaging |
Het |
| Ttc41 |
C |
T |
10: 86,566,989 (GRCm39) |
R552C |
probably benign |
Het |
| Vit |
T |
C |
17: 78,909,308 (GRCm39) |
S252P |
probably benign |
Het |
| Vma21-ps |
T |
A |
4: 52,496,943 (GRCm39) |
D101V |
probably damaging |
Het |
| Vmn1r173 |
A |
T |
7: 23,402,361 (GRCm39) |
I199F |
probably damaging |
Het |
| Vmn2r114 |
T |
A |
17: 23,529,336 (GRCm39) |
R255S |
probably benign |
Het |
| Vmn2r17 |
A |
G |
5: 109,582,246 (GRCm39) |
N545S |
probably damaging |
Het |
| Zfp865 |
A |
G |
7: 5,034,640 (GRCm39) |
Y875C |
probably damaging |
Het |
|
| Other mutations in Myh9 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00796:Myh9
|
APN |
15 |
77,681,195 (GRCm39) |
splice site |
probably benign |
|
|
IGL01105:Myh9
|
APN |
15 |
77,665,678 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01137:Myh9
|
APN |
15 |
77,653,742 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL01399:Myh9
|
APN |
15 |
77,651,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01666:Myh9
|
APN |
15 |
77,646,131 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL01832:Myh9
|
APN |
15 |
77,675,953 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01933:Myh9
|
APN |
15 |
77,665,418 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02049:Myh9
|
APN |
15 |
77,654,070 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02237:Myh9
|
APN |
15 |
77,670,854 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02243:Myh9
|
APN |
15 |
77,651,682 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02248:Myh9
|
APN |
15 |
77,670,814 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02292:Myh9
|
APN |
15 |
77,692,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02315:Myh9
|
APN |
15 |
77,654,173 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02427:Myh9
|
APN |
15 |
77,660,004 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02675:Myh9
|
APN |
15 |
77,673,130 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02727:Myh9
|
APN |
15 |
77,675,942 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL02749:Myh9
|
APN |
15 |
77,692,186 (GRCm39) |
nonsense |
probably null |
|
|
IGL02887:Myh9
|
APN |
15 |
77,680,220 (GRCm39) |
nonsense |
probably null |
|
|
IGL02926:Myh9
|
APN |
15 |
77,671,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02945:Myh9
|
APN |
15 |
77,646,205 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03137:Myh9
|
APN |
15 |
77,675,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0784:Myh9
|
UTSW |
15 |
77,661,209 (GRCm39) |
splice site |
probably benign |
|
|
R1375:Myh9
|
UTSW |
15 |
77,653,568 (GRCm39) |
splice site |
probably null |
|
|
R1535:Myh9
|
UTSW |
15 |
77,662,013 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1563:Myh9
|
UTSW |
15 |
77,656,057 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1629:Myh9
|
UTSW |
15 |
77,648,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1635:Myh9
|
UTSW |
15 |
77,660,099 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1635:Myh9
|
UTSW |
15 |
77,655,367 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1693:Myh9
|
UTSW |
15 |
77,697,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1791:Myh9
|
UTSW |
15 |
77,657,464 (GRCm39) |
unclassified |
probably benign |
|
|
R2010:Myh9
|
UTSW |
15 |
77,656,147 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2048:Myh9
|
UTSW |
15 |
77,655,332 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R2078:Myh9
|
UTSW |
15 |
77,648,112 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2092:Myh9
|
UTSW |
15 |
77,648,550 (GRCm39) |
nonsense |
probably null |
|
|
R2376:Myh9
|
UTSW |
15 |
77,667,617 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2922:Myh9
|
UTSW |
15 |
77,697,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3709:Myh9
|
UTSW |
15 |
77,657,547 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R3710:Myh9
|
UTSW |
15 |
77,657,547 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R3737:Myh9
|
UTSW |
15 |
77,651,012 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3738:Myh9
|
UTSW |
15 |
77,651,012 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3739:Myh9
|
UTSW |
15 |
77,651,012 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4299:Myh9
|
UTSW |
15 |
77,654,164 (GRCm39) |
missense |
probably benign |
|
|
R4384:Myh9
|
UTSW |
15 |
77,675,912 (GRCm39) |
splice site |
probably benign |
|
|
R4514:Myh9
|
UTSW |
15 |
77,648,200 (GRCm39) |
missense |
probably benign |
|
|
R4631:Myh9
|
UTSW |
15 |
77,681,228 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4642:Myh9
|
UTSW |
15 |
77,646,151 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4695:Myh9
|
UTSW |
15 |
77,653,053 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4709:Myh9
|
UTSW |
15 |
77,671,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4766:Myh9
|
UTSW |
15 |
77,692,077 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4826:Myh9
|
UTSW |
15 |
77,673,146 (GRCm39) |
nonsense |
probably null |
|
|
R4946:Myh9
|
UTSW |
15 |
77,657,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5030:Myh9
|
UTSW |
15 |
77,691,998 (GRCm39) |
intron |
probably benign |
|
|
R5055:Myh9
|
UTSW |
15 |
77,648,723 (GRCm39) |
missense |
probably benign |
0.12 |
|
R5202:Myh9
|
UTSW |
15 |
77,665,310 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5413:Myh9
|
UTSW |
15 |
77,692,186 (GRCm39) |
nonsense |
probably null |
|
|
R5435:Myh9
|
UTSW |
15 |
77,653,809 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5701:Myh9
|
UTSW |
15 |
77,675,964 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5757:Myh9
|
UTSW |
15 |
77,655,362 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5793:Myh9
|
UTSW |
15 |
77,653,077 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5952:Myh9
|
UTSW |
15 |
77,657,532 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6248:Myh9
|
UTSW |
15 |
77,669,422 (GRCm39) |
nonsense |
probably null |
|
|
R6648:Myh9
|
UTSW |
15 |
77,650,972 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7055:Myh9
|
UTSW |
15 |
77,659,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7106:Myh9
|
UTSW |
15 |
77,659,321 (GRCm39) |
missense |
probably benign |
|
|
R7180:Myh9
|
UTSW |
15 |
77,692,110 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7205:Myh9
|
UTSW |
15 |
77,667,672 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7254:Myh9
|
UTSW |
15 |
77,650,024 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7284:Myh9
|
UTSW |
15 |
77,671,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7417:Myh9
|
UTSW |
15 |
77,648,065 (GRCm39) |
nonsense |
probably null |
|
|
R7695:Myh9
|
UTSW |
15 |
77,650,936 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7750:Myh9
|
UTSW |
15 |
77,667,610 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7854:Myh9
|
UTSW |
15 |
77,675,953 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8220:Myh9
|
UTSW |
15 |
77,648,747 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8324:Myh9
|
UTSW |
15 |
77,673,117 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8837:Myh9
|
UTSW |
15 |
77,661,137 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8944:Myh9
|
UTSW |
15 |
77,655,432 (GRCm39) |
missense |
probably benign |
|
|
R9025:Myh9
|
UTSW |
15 |
77,653,192 (GRCm39) |
missense |
probably benign |
|
|
R9229:Myh9
|
UTSW |
15 |
77,675,017 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9396:Myh9
|
UTSW |
15 |
77,647,496 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Myh9
|
UTSW |
15 |
77,659,458 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGGAAGTGATGCAAACACCC -3'
(R):5'- ACGCTTCTTGCTTGCAGACAG -3'
Sequencing Primer
(F):5'- GTGATGCAAACACCCACACTGG -3'
(R):5'- TCTTGCTTGCAGACAGACCAC -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation