Incidental Mutation 'R4884:Cep295'
| ID |
375550 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cep295
|
| Ensembl Gene |
ENSMUSG00000046111 |
| Gene Name |
centrosomal protein 295 |
| Synonyms |
5830418K08Rik, LOC382128 |
| MMRRC Submission |
041978-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.952)
|
| Stock # |
R4884 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
15228211-15269084 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 15263056 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 169
(E169G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000096578
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000098979]
[ENSMUST00000161132]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000098979
AA Change: E169G
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000096578
Gene: ENSMUSG00000046111
AA Change: E169G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
159 |
175 |
N/A |
INTRINSIC |
|
coiled coil region
|
258 |
288 |
N/A |
INTRINSIC |
|
coiled coil region
|
536 |
583 |
N/A |
INTRINSIC |
|
coiled coil region
|
861 |
889 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
890 |
1104 |
6.8e-5 |
PROSPERO |
|
internal_repeat_1
|
1277 |
1489 |
6.8e-5 |
PROSPERO |
|
low complexity region
|
1537 |
1548 |
N/A |
INTRINSIC |
|
low complexity region
|
1611 |
1625 |
N/A |
INTRINSIC |
|
coiled coil region
|
1707 |
1736 |
N/A |
INTRINSIC |
|
low complexity region
|
2003 |
2018 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000160692
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000161132
AA Change: E169G
PolyPhen 2
Score 0.977 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000123788
Gene: ENSMUSG00000046111
AA Change: E169G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
111 |
127 |
N/A |
INTRINSIC |
|
coiled coil region
|
210 |
240 |
N/A |
INTRINSIC |
|
coiled coil region
|
488 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
813 |
841 |
N/A |
INTRINSIC |
|
coiled coil region
|
1300 |
1327 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1500 |
N/A |
INTRINSIC |
|
low complexity region
|
1563 |
1577 |
N/A |
INTRINSIC |
|
coiled coil region
|
1659 |
1688 |
N/A |
INTRINSIC |
|
low complexity region
|
2035 |
2050 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000161795
AA Change: E121G
PolyPhen 2
Score 0.976 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000125035
Gene: ENSMUSG00000046111
AA Change: E121G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
111 |
127 |
N/A |
INTRINSIC |
|
coiled coil region
|
210 |
240 |
N/A |
INTRINSIC |
|
coiled coil region
|
488 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
813 |
841 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
842 |
1056 |
7.14e-5 |
PROSPERO |
|
internal_repeat_1
|
1229 |
1441 |
7.14e-5 |
PROSPERO |
|
low complexity region
|
1489 |
1500 |
N/A |
INTRINSIC |
|
low complexity region
|
1563 |
1577 |
N/A |
INTRINSIC |
|
coiled coil region
|
1659 |
1688 |
N/A |
INTRINSIC |
|
low complexity region
|
1955 |
1970 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000162689
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000163010
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 93.5%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 113 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2700049A03Rik |
G |
T |
12: 71,211,320 (GRCm39) |
E685* |
probably null |
Het |
| 2700049A03Rik |
A |
T |
12: 71,211,321 (GRCm39) |
E685V |
possibly damaging |
Het |
| Aadat |
C |
T |
8: 60,979,663 (GRCm39) |
P175L |
probably damaging |
Het |
| Acot7 |
G |
T |
4: 152,270,664 (GRCm39) |
|
probably benign |
Het |
| Adad1 |
T |
G |
3: 37,130,813 (GRCm39) |
F259V |
possibly damaging |
Het |
| Adora2a |
A |
G |
10: 75,161,879 (GRCm39) |
Y6C |
probably null |
Het |
| Ahnak |
A |
G |
19: 8,990,118 (GRCm39) |
|
probably benign |
Het |
| Ankar |
A |
T |
1: 72,737,966 (GRCm39) |
M72K |
probably damaging |
Het |
| Ankrd45 |
A |
G |
1: 160,988,270 (GRCm39) |
K176R |
possibly damaging |
Het |
| Ap3m2 |
T |
C |
8: 23,293,997 (GRCm39) |
K18E |
probably damaging |
Het |
| Apol10b |
C |
T |
15: 77,473,006 (GRCm39) |
R16Q |
possibly damaging |
Het |
| Atp2b2 |
T |
A |
6: 113,819,147 (GRCm39) |
T49S |
possibly damaging |
Het |
| B3gntl1 |
T |
G |
11: 121,520,795 (GRCm39) |
Y206S |
possibly damaging |
Het |
| BC061237 |
G |
A |
14: 44,738,666 (GRCm39) |
E22K |
possibly damaging |
Het |
| Bmp1 |
A |
G |
14: 70,712,655 (GRCm39) |
V959A |
probably benign |
Het |
| Cfap20dc |
G |
A |
14: 8,578,394 (GRCm38) |
T116I |
probably damaging |
Het |
| Cfap65 |
T |
G |
1: 74,942,283 (GRCm39) |
E1757A |
possibly damaging |
Het |
| Cgrrf1 |
T |
A |
14: 47,090,912 (GRCm39) |
I216N |
possibly damaging |
Het |
| Clstn2 |
T |
A |
9: 97,681,448 (GRCm39) |
D64V |
probably damaging |
Het |
| Col27a1 |
T |
A |
4: 63,194,197 (GRCm39) |
D851E |
possibly damaging |
Het |
| Coq9 |
C |
T |
8: 95,579,822 (GRCm39) |
P259L |
probably benign |
Het |
| Cps1 |
A |
G |
1: 67,216,183 (GRCm39) |
N836S |
probably benign |
Het |
| Cracd |
A |
T |
5: 76,996,682 (GRCm39) |
I47F |
probably damaging |
Het |
| Crebbp |
T |
C |
16: 3,906,239 (GRCm39) |
K1588E |
probably damaging |
Het |
| Cspg4 |
T |
C |
9: 56,805,353 (GRCm39) |
W2055R |
probably benign |
Het |
| Cyp3a44 |
A |
T |
5: 145,714,792 (GRCm39) |
M453K |
probably damaging |
Het |
| Dhx36 |
T |
G |
3: 62,391,681 (GRCm39) |
D555A |
probably damaging |
Het |
| Dock2 |
A |
T |
11: 34,216,248 (GRCm39) |
Y1219N |
probably damaging |
Het |
| Dpy19l2 |
A |
T |
9: 24,539,476 (GRCm39) |
C492* |
probably null |
Het |
| Dusp22 |
A |
G |
13: 30,852,813 (GRCm39) |
N16S |
probably benign |
Het |
| Epha1 |
A |
G |
6: 42,337,668 (GRCm39) |
M805T |
probably damaging |
Het |
| Espl1 |
C |
T |
15: 102,232,505 (GRCm39) |
A2071V |
possibly damaging |
Het |
| Fbxo11 |
T |
A |
17: 88,299,761 (GRCm39) |
D863V |
probably damaging |
Het |
| Fbxo7 |
T |
A |
10: 85,865,014 (GRCm39) |
Y106N |
probably damaging |
Het |
| Fhip1a |
A |
C |
3: 85,590,918 (GRCm39) |
C178G |
probably damaging |
Het |
| Fst |
A |
G |
13: 114,590,920 (GRCm39) |
V282A |
probably damaging |
Het |
| Gfra3 |
T |
A |
18: 34,844,304 (GRCm39) |
M79L |
probably benign |
Het |
| Glp1r |
T |
C |
17: 31,155,240 (GRCm39) |
V409A |
probably damaging |
Het |
| Gm10799 |
T |
A |
2: 103,898,552 (GRCm39) |
D51V |
probably damaging |
Het |
| Gm572 |
C |
A |
4: 148,751,819 (GRCm39) |
T228N |
possibly damaging |
Het |
| Grip1 |
C |
T |
10: 119,911,211 (GRCm39) |
T643M |
probably damaging |
Het |
| Hdgfl2 |
C |
T |
17: 56,403,265 (GRCm39) |
R222C |
possibly damaging |
Het |
| Hecw2 |
T |
A |
1: 53,990,000 (GRCm39) |
I125F |
probably benign |
Het |
| Hipk1 |
A |
G |
3: 103,651,338 (GRCm39) |
S1153P |
possibly damaging |
Het |
| Insm2 |
T |
C |
12: 55,646,546 (GRCm39) |
S97P |
probably damaging |
Het |
| Iqca1 |
A |
G |
1: 90,067,759 (GRCm39) |
V164A |
probably benign |
Het |
| Kcna6 |
T |
C |
6: 126,715,689 (GRCm39) |
D400G |
probably benign |
Het |
| Kctd1 |
T |
C |
18: 15,107,311 (GRCm39) |
Y122C |
probably damaging |
Het |
| Klk14 |
G |
A |
7: 43,341,501 (GRCm39) |
C51Y |
probably damaging |
Het |
| Klra2 |
T |
C |
6: 131,207,165 (GRCm39) |
Y148C |
probably damaging |
Het |
| Krtap31-1 |
G |
A |
11: 99,799,310 (GRCm39) |
C171Y |
unknown |
Het |
| Ldlrap1 |
C |
T |
4: 134,486,282 (GRCm39) |
R59Q |
probably benign |
Het |
| Ltb |
T |
C |
17: 35,414,234 (GRCm39) |
I3T |
probably benign |
Het |
| Macf1 |
T |
C |
4: 123,348,802 (GRCm39) |
I2477V |
probably benign |
Het |
| Mpdz |
A |
T |
4: 81,279,713 (GRCm39) |
I39N |
probably damaging |
Het |
| Mtcl3 |
A |
T |
10: 29,072,537 (GRCm39) |
N610Y |
probably damaging |
Het |
| Mycbp2 |
A |
G |
14: 103,448,731 (GRCm39) |
I1776T |
probably damaging |
Het |
| Myof |
T |
A |
19: 37,930,805 (GRCm39) |
E994V |
probably damaging |
Het |
| Myom3 |
A |
G |
4: 135,510,366 (GRCm39) |
E553G |
possibly damaging |
Het |
| Mysm1 |
A |
T |
4: 94,847,185 (GRCm39) |
C504S |
probably damaging |
Het |
| Nectin3 |
A |
T |
16: 46,269,249 (GRCm39) |
H384Q |
probably benign |
Het |
| Net1 |
G |
A |
13: 3,934,252 (GRCm39) |
R482* |
probably null |
Het |
| Nit1 |
T |
C |
1: 171,171,263 (GRCm39) |
K193R |
probably null |
Het |
| Nlgn1 |
A |
G |
3: 25,966,838 (GRCm39) |
V205A |
probably damaging |
Het |
| Nr3c2 |
A |
T |
8: 77,635,438 (GRCm39) |
I180F |
possibly damaging |
Het |
| Nup50l |
A |
T |
6: 96,141,793 (GRCm39) |
M417K |
probably damaging |
Het |
| Nup62 |
T |
A |
7: 44,478,289 (GRCm39) |
S101R |
probably damaging |
Het |
| Or13c7 |
T |
C |
4: 43,854,890 (GRCm39) |
S194P |
probably damaging |
Het |
| Or1l8 |
G |
T |
2: 36,818,024 (GRCm39) |
T34K |
possibly damaging |
Het |
| Or4c3 |
A |
G |
2: 89,851,987 (GRCm39) |
V141A |
probably benign |
Het |
| Or51b17 |
T |
A |
7: 103,542,862 (GRCm39) |
I27F |
probably benign |
Het |
| Or56b2j |
T |
A |
7: 104,353,068 (GRCm39) |
I98N |
probably damaging |
Het |
| Or5b111 |
A |
T |
19: 13,291,034 (GRCm39) |
I205N |
probably benign |
Het |
| Or5b124 |
A |
T |
19: 13,611,391 (GRCm39) |
K305N |
probably benign |
Het |
| Or5p80 |
A |
T |
7: 108,229,819 (GRCm39) |
I207F |
probably damaging |
Het |
| Osbpl6 |
A |
T |
2: 76,379,883 (GRCm39) |
I158F |
probably damaging |
Het |
| Pcbp4 |
A |
G |
9: 106,339,301 (GRCm39) |
T103A |
probably benign |
Het |
| Pcdha2 |
T |
A |
18: 37,073,953 (GRCm39) |
L528Q |
probably damaging |
Het |
| Pcdhga5 |
T |
C |
18: 37,827,680 (GRCm39) |
S43P |
probably damaging |
Het |
| Pdgfra |
C |
A |
5: 75,349,973 (GRCm39) |
N952K |
probably benign |
Het |
| Pla2r1 |
A |
G |
2: 60,365,328 (GRCm39) |
S81P |
probably damaging |
Het |
| Rabggtb |
A |
T |
3: 153,617,568 (GRCm39) |
D43E |
possibly damaging |
Het |
| Rexo5 |
T |
A |
7: 119,424,774 (GRCm39) |
C43* |
probably null |
Het |
| Robo1 |
T |
A |
16: 72,701,639 (GRCm39) |
D168E |
probably damaging |
Het |
| Saxo4 |
A |
T |
19: 10,451,865 (GRCm39) |
*428R |
probably null |
Het |
| Scimp |
A |
G |
11: 70,688,865 (GRCm39) |
M49T |
unknown |
Het |
| Sema3e |
T |
A |
5: 14,275,579 (GRCm39) |
V228E |
probably damaging |
Het |
| Sema6d |
A |
G |
2: 124,498,738 (GRCm39) |
|
probably null |
Het |
| Serpinb6d |
A |
T |
13: 33,850,428 (GRCm39) |
D85V |
possibly damaging |
Het |
| Slc24a2 |
C |
T |
4: 86,909,745 (GRCm39) |
V658I |
probably damaging |
Het |
| Snd1 |
T |
C |
6: 28,526,911 (GRCm39) |
I198T |
possibly damaging |
Het |
| Snx33 |
C |
T |
9: 56,833,464 (GRCm39) |
V202M |
probably damaging |
Het |
| Srcap |
A |
G |
7: 127,121,189 (GRCm39) |
E174G |
probably damaging |
Het |
| Srgap2 |
C |
A |
1: 131,220,314 (GRCm39) |
|
probably null |
Het |
| Stxbp5 |
A |
T |
10: 9,688,085 (GRCm39) |
Y405* |
probably null |
Het |
| Thsd4 |
C |
T |
9: 59,895,320 (GRCm39) |
R710H |
probably benign |
Het |
| Trp53inp1 |
T |
A |
4: 11,165,130 (GRCm39) |
D51E |
probably benign |
Het |
| Ttc41 |
A |
G |
10: 86,566,882 (GRCm39) |
D516G |
probably benign |
Het |
| Tut7 |
A |
T |
13: 59,937,266 (GRCm39) |
L775H |
probably damaging |
Het |
| Uap1l1 |
A |
G |
2: 25,252,840 (GRCm39) |
V400A |
probably damaging |
Het |
| Vit |
T |
C |
17: 78,932,182 (GRCm39) |
S430P |
probably damaging |
Het |
| Vmn1r9 |
T |
A |
6: 57,048,294 (GRCm39) |
M123K |
possibly damaging |
Het |
| Vmn2r14 |
A |
T |
5: 109,369,384 (GRCm39) |
|
probably null |
Het |
| Vwa3a |
A |
G |
7: 120,390,924 (GRCm39) |
T746A |
probably benign |
Het |
| Wdfy4 |
G |
T |
14: 32,710,852 (GRCm39) |
Y2578* |
probably null |
Het |
| Wdr53 |
A |
T |
16: 32,075,796 (GRCm39) |
K334* |
probably null |
Het |
| Xpot |
G |
T |
10: 121,442,713 (GRCm39) |
H495Q |
probably damaging |
Het |
| Zfp109 |
T |
C |
7: 23,928,570 (GRCm39) |
T288A |
probably benign |
Het |
| Zfp277 |
T |
A |
12: 40,413,152 (GRCm39) |
E276V |
probably damaging |
Het |
| Zfp703 |
A |
G |
8: 27,468,729 (GRCm39) |
D131G |
probably benign |
Het |
| Zfp985 |
T |
A |
4: 147,667,801 (GRCm39) |
I223N |
probably benign |
Het |
| Zrsr2-ps1 |
T |
C |
11: 22,923,805 (GRCm39) |
V193A |
possibly damaging |
Het |
| Zscan20 |
A |
G |
4: 128,481,958 (GRCm39) |
I568T |
possibly damaging |
Het |
|
| Other mutations in Cep295 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Cep295
|
APN |
9 |
15,237,368 (GRCm39) |
splice site |
probably null |
|
|
IGL00769:Cep295
|
APN |
9 |
15,237,440 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00771:Cep295
|
APN |
9 |
15,233,861 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00850:Cep295
|
APN |
9 |
15,234,148 (GRCm39) |
missense |
probably benign |
0.36 |
|
IGL01505:Cep295
|
APN |
9 |
15,229,345 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01510:Cep295
|
APN |
9 |
15,265,922 (GRCm39) |
nonsense |
probably null |
|
|
IGL01759:Cep295
|
APN |
9 |
15,234,855 (GRCm39) |
splice site |
probably null |
|
|
IGL02415:Cep295
|
APN |
9 |
15,264,316 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02447:Cep295
|
APN |
9 |
15,243,807 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02502:Cep295
|
APN |
9 |
15,262,209 (GRCm39) |
splice site |
probably benign |
|
|
IGL02665:Cep295
|
APN |
9 |
15,237,928 (GRCm39) |
splice site |
probably benign |
|
|
IGL02718:Cep295
|
APN |
9 |
15,237,049 (GRCm39) |
splice site |
probably null |
|
|
IGL02995:Cep295
|
APN |
9 |
15,244,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03024:Cep295
|
APN |
9 |
15,236,868 (GRCm39) |
missense |
probably benign |
|
|
R0196:Cep295
|
UTSW |
9 |
15,249,509 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0398:Cep295
|
UTSW |
9 |
15,266,032 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0595:Cep295
|
UTSW |
9 |
15,243,487 (GRCm39) |
nonsense |
probably null |
|
|
R0610:Cep295
|
UTSW |
9 |
15,234,050 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R0616:Cep295
|
UTSW |
9 |
15,243,618 (GRCm39) |
nonsense |
probably null |
|
|
R0840:Cep295
|
UTSW |
9 |
15,245,611 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1215:Cep295
|
UTSW |
9 |
15,239,178 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1376:Cep295
|
UTSW |
9 |
15,252,164 (GRCm39) |
splice site |
probably benign |
|
|
R1381:Cep295
|
UTSW |
9 |
15,233,861 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1484:Cep295
|
UTSW |
9 |
15,246,080 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1557:Cep295
|
UTSW |
9 |
15,243,306 (GRCm39) |
nonsense |
probably null |
|
|
R1655:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1682:Cep295
|
UTSW |
9 |
15,245,217 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1700:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1734:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1736:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1743:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1765:Cep295
|
UTSW |
9 |
15,239,200 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1889:Cep295
|
UTSW |
9 |
15,243,399 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1895:Cep295
|
UTSW |
9 |
15,243,399 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1994:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1995:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2071:Cep295
|
UTSW |
9 |
15,252,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2161:Cep295
|
UTSW |
9 |
15,264,354 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2195:Cep295
|
UTSW |
9 |
15,243,617 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2354:Cep295
|
UTSW |
9 |
15,246,080 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2427:Cep295
|
UTSW |
9 |
15,245,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2992:Cep295
|
UTSW |
9 |
15,244,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3873:Cep295
|
UTSW |
9 |
15,244,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3981:Cep295
|
UTSW |
9 |
15,228,363 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4201:Cep295
|
UTSW |
9 |
15,243,834 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4297:Cep295
|
UTSW |
9 |
15,233,950 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4543:Cep295
|
UTSW |
9 |
15,246,549 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4584:Cep295
|
UTSW |
9 |
15,246,095 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R4724:Cep295
|
UTSW |
9 |
15,242,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4878:Cep295
|
UTSW |
9 |
15,246,252 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4934:Cep295
|
UTSW |
9 |
15,244,456 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4990:Cep295
|
UTSW |
9 |
15,243,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5057:Cep295
|
UTSW |
9 |
15,233,979 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5153:Cep295
|
UTSW |
9 |
15,268,925 (GRCm39) |
missense |
probably benign |
0.32 |
|
R5180:Cep295
|
UTSW |
9 |
15,243,416 (GRCm39) |
missense |
probably benign |
|
|
R5285:Cep295
|
UTSW |
9 |
15,233,887 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5360:Cep295
|
UTSW |
9 |
15,238,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5419:Cep295
|
UTSW |
9 |
15,235,533 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5432:Cep295
|
UTSW |
9 |
15,262,991 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5625:Cep295
|
UTSW |
9 |
15,252,187 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5637:Cep295
|
UTSW |
9 |
15,245,108 (GRCm39) |
splice site |
probably null |
|
|
R5645:Cep295
|
UTSW |
9 |
15,246,404 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5645:Cep295
|
UTSW |
9 |
15,244,090 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5678:Cep295
|
UTSW |
9 |
15,234,154 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5688:Cep295
|
UTSW |
9 |
15,243,282 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5807:Cep295
|
UTSW |
9 |
15,243,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5824:Cep295
|
UTSW |
9 |
15,236,952 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5837:Cep295
|
UTSW |
9 |
15,258,280 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5915:Cep295
|
UTSW |
9 |
15,252,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5988:Cep295
|
UTSW |
9 |
15,252,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6239:Cep295
|
UTSW |
9 |
15,233,927 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6332:Cep295
|
UTSW |
9 |
15,246,210 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6383:Cep295
|
UTSW |
9 |
15,244,050 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6737:Cep295
|
UTSW |
9 |
15,243,647 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6929:Cep295
|
UTSW |
9 |
15,244,358 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7428:Cep295
|
UTSW |
9 |
15,244,794 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R7697:Cep295
|
UTSW |
9 |
15,266,006 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7963:Cep295
|
UTSW |
9 |
15,244,737 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8055:Cep295
|
UTSW |
9 |
15,244,905 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8069:Cep295
|
UTSW |
9 |
15,233,882 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8092:Cep295
|
UTSW |
9 |
15,244,278 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8117:Cep295
|
UTSW |
9 |
15,245,660 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8140:Cep295
|
UTSW |
9 |
15,252,829 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8178:Cep295
|
UTSW |
9 |
15,244,836 (GRCm39) |
missense |
|
|
|
R8323:Cep295
|
UTSW |
9 |
15,264,357 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8323:Cep295
|
UTSW |
9 |
15,249,529 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8339:Cep295
|
UTSW |
9 |
15,236,846 (GRCm39) |
missense |
|
|
|
R8351:Cep295
|
UTSW |
9 |
15,234,202 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8367:Cep295
|
UTSW |
9 |
15,245,826 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8725:Cep295
|
UTSW |
9 |
15,243,715 (GRCm39) |
nonsense |
probably null |
|
|
R8919:Cep295
|
UTSW |
9 |
15,238,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9015:Cep295
|
UTSW |
9 |
15,244,264 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9054:Cep295
|
UTSW |
9 |
15,235,551 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9088:Cep295
|
UTSW |
9 |
15,233,815 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9159:Cep295
|
UTSW |
9 |
15,252,904 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9243:Cep295
|
UTSW |
9 |
15,243,605 (GRCm39) |
missense |
probably benign |
0.36 |
|
R9408:Cep295
|
UTSW |
9 |
15,244,619 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9424:Cep295
|
UTSW |
9 |
15,244,499 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9455:Cep295
|
UTSW |
9 |
15,245,046 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9607:Cep295
|
UTSW |
9 |
15,234,009 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9648:Cep295
|
UTSW |
9 |
15,234,903 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9659:Cep295
|
UTSW |
9 |
15,233,846 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9731:Cep295
|
UTSW |
9 |
15,245,262 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
X0065:Cep295
|
UTSW |
9 |
15,234,187 (GRCm39) |
missense |
probably benign |
0.36 |
|
Z1176:Cep295
|
UTSW |
9 |
15,268,993 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Cep295
|
UTSW |
9 |
15,242,113 (GRCm39) |
missense |
|
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGTAAGGCCTGCCGCATTAG -3'
(R):5'- TCCCATTGCCATGCTTTGGG -3'
Sequencing Primer
(F):5'- CGCATTAGTGAGCACAGGTC -3'
(R):5'- CCATGCTTTGGGAGATATTTGTGGAC -3'
|
| Posted On |
2016-03-17 |
Incidental Mutation