Incidental Mutation 'IGL03190:Zfp811'
| ID |
412631 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Zfp811
|
| Ensembl Gene |
ENSMUSG00000055202 |
| Gene Name |
zinc finger protein 811 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.059)
|
| Stock # |
IGL03190
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
17 |
| Chromosomal Location |
33014650-33028905 bp(-) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
A to G
at 33017855 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000144038
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000080905]
[ENSMUST00000200914]
|
| AlphaFold |
A0A0J9YU71 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000080905
|
| SMART Domains |
Protein: ENSMUSP00000079709
Gene: ENSMUSG00000055202
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
3 |
62 |
6.26e-16 |
SMART |
|
ZnF_C2H2
|
192 |
215 |
1.25e-1 |
SMART |
|
ZnF_C2H2
|
220 |
242 |
1.79e-2 |
SMART |
|
ZnF_C2H2
|
248 |
270 |
9.08e-4 |
SMART |
|
ZnF_C2H2
|
276 |
298 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
304 |
326 |
3.69e-4 |
SMART |
|
ZnF_C2H2
|
332 |
354 |
8.47e-4 |
SMART |
|
ZnF_C2H2
|
360 |
382 |
1.45e-2 |
SMART |
|
ZnF_C2H2
|
388 |
410 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
416 |
438 |
5.9e-3 |
SMART |
|
ZnF_C2H2
|
444 |
466 |
1.08e-1 |
SMART |
|
ZnF_C2H2
|
472 |
494 |
2.75e-3 |
SMART |
|
ZnF_C2H2
|
500 |
522 |
9.44e-2 |
SMART |
|
ZnF_C2H2
|
528 |
551 |
3.89e-3 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000104150
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000200914
|
| SMART Domains |
Protein: ENSMUSP00000144038
Gene: ENSMUSG00000055202
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
4 |
63 |
2.6e-18 |
SMART |
|
ZnF_C2H2
|
193 |
216 |
5.4e-4 |
SMART |
|
ZnF_C2H2
|
221 |
243 |
7.8e-5 |
SMART |
|
ZnF_C2H2
|
249 |
271 |
3.8e-6 |
SMART |
|
ZnF_C2H2
|
277 |
299 |
3.3e-5 |
SMART |
|
ZnF_C2H2
|
305 |
327 |
1.6e-6 |
SMART |
|
ZnF_C2H2
|
333 |
355 |
3.8e-6 |
SMART |
|
ZnF_C2H2
|
361 |
383 |
6.1e-5 |
SMART |
|
ZnF_C2H2
|
389 |
411 |
2.7e-6 |
SMART |
|
ZnF_C2H2
|
417 |
439 |
2.5e-5 |
SMART |
|
ZnF_C2H2
|
445 |
467 |
4.6e-4 |
SMART |
|
ZnF_C2H2
|
473 |
495 |
1.2e-5 |
SMART |
|
ZnF_C2H2
|
501 |
523 |
4e-4 |
SMART |
|
ZnF_C2H2
|
529 |
552 |
1.7e-5 |
SMART |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 37 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adcy4 |
A |
T |
14: 56,016,510 (GRCm39) |
C314S |
probably damaging |
Het |
| Agr2 |
T |
A |
12: 36,048,634 (GRCm39) |
I128N |
probably damaging |
Het |
| Akr1c6 |
T |
C |
13: 4,496,412 (GRCm39) |
I91T |
possibly damaging |
Het |
| Ankrd45 |
A |
G |
1: 160,990,909 (GRCm39) |
I221V |
probably benign |
Het |
| Armc3 |
A |
T |
2: 19,293,761 (GRCm39) |
L517F |
probably damaging |
Het |
| Atp13a3 |
A |
T |
16: 30,141,766 (GRCm39) |
M1129K |
probably benign |
Het |
| Atp6v0a4 |
T |
A |
6: 38,031,491 (GRCm39) |
Q670L |
probably benign |
Het |
| Bank1 |
T |
C |
3: 135,806,185 (GRCm39) |
Y483C |
probably damaging |
Het |
| Bcan |
A |
T |
3: 87,900,357 (GRCm39) |
|
probably benign |
Het |
| Bcl11a |
G |
A |
11: 24,108,333 (GRCm39) |
E104K |
probably benign |
Het |
| Clasp2 |
C |
T |
9: 113,673,208 (GRCm39) |
Q368* |
probably null |
Het |
| Clcn1 |
T |
A |
6: 42,267,037 (GRCm39) |
Y71N |
probably benign |
Het |
| Cul2 |
C |
T |
18: 3,429,634 (GRCm39) |
T498I |
possibly damaging |
Het |
| Fat4 |
A |
G |
3: 39,035,390 (GRCm39) |
D3014G |
probably damaging |
Het |
| Flnc |
T |
C |
6: 29,445,636 (GRCm39) |
|
probably benign |
Het |
| Il36g |
C |
A |
2: 24,077,272 (GRCm39) |
S28* |
probably null |
Het |
| Itgb3bp |
A |
G |
4: 99,677,923 (GRCm39) |
|
probably benign |
Het |
| Itm2b |
G |
A |
14: 73,603,229 (GRCm39) |
P120L |
probably damaging |
Het |
| Klk1b26 |
T |
C |
7: 43,662,151 (GRCm39) |
F3S |
possibly damaging |
Het |
| Lin52 |
T |
C |
12: 84,504,732 (GRCm39) |
V39A |
probably damaging |
Het |
| Magt1 |
A |
C |
X: 105,032,622 (GRCm39) |
N242K |
probably benign |
Het |
| Nos3 |
A |
G |
5: 24,588,627 (GRCm39) |
M1118V |
probably damaging |
Het |
| Or1j13 |
A |
T |
2: 36,369,734 (GRCm39) |
M136K |
probably damaging |
Het |
| Or6k2 |
T |
C |
1: 173,987,110 (GRCm39) |
V257A |
probably damaging |
Het |
| Paqr5 |
A |
C |
9: 61,880,084 (GRCm39) |
L56R |
probably damaging |
Het |
| Pcdhb16 |
T |
C |
18: 37,612,396 (GRCm39) |
F452S |
probably damaging |
Het |
| Prdm5 |
T |
A |
6: 65,833,116 (GRCm39) |
|
probably benign |
Het |
| Rps6ka5 |
A |
G |
12: 100,524,907 (GRCm39) |
|
probably benign |
Het |
| Slc22a5 |
A |
G |
11: 53,765,840 (GRCm39) |
F249L |
probably benign |
Het |
| Spata31f1a |
C |
A |
4: 42,848,362 (GRCm39) |
G1265C |
probably benign |
Het |
| Ttll2 |
T |
C |
17: 7,618,779 (GRCm39) |
K383E |
probably benign |
Het |
| Ube2o |
G |
A |
11: 116,435,954 (GRCm39) |
P353L |
probably damaging |
Het |
| Vmn1r63 |
T |
C |
7: 5,806,110 (GRCm39) |
D174G |
probably benign |
Het |
| Vmn2r82 |
A |
G |
10: 79,192,643 (GRCm39) |
|
probably null |
Het |
| Xpnpep2 |
T |
A |
X: 47,207,205 (GRCm39) |
|
probably benign |
Het |
| Zfp352 |
T |
A |
4: 90,111,994 (GRCm39) |
S45T |
possibly damaging |
Het |
| Zfyve19 |
G |
A |
2: 119,046,717 (GRCm39) |
A304T |
probably damaging |
Het |
|
| Other mutations in Zfp811 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01394:Zfp811
|
APN |
17 |
33,016,794 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02227:Zfp811
|
APN |
17 |
33,017,616 (GRCm39) |
nonsense |
probably null |
|
|
IGL02529:Zfp811
|
APN |
17 |
33,016,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0112:Zfp811
|
UTSW |
17 |
33,016,738 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1025:Zfp811
|
UTSW |
17 |
33,017,618 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1522:Zfp811
|
UTSW |
17 |
33,016,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1829:Zfp811
|
UTSW |
17 |
33,017,116 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R1861:Zfp811
|
UTSW |
17 |
33,016,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2181:Zfp811
|
UTSW |
17 |
33,016,695 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4360:Zfp811
|
UTSW |
17 |
33,017,432 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4425:Zfp811
|
UTSW |
17 |
33,016,521 (GRCm39) |
nonsense |
probably null |
|
|
R4657:Zfp811
|
UTSW |
17 |
33,019,897 (GRCm39) |
nonsense |
probably null |
|
|
R6066:Zfp811
|
UTSW |
17 |
33,017,801 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R6109:Zfp811
|
UTSW |
17 |
33,016,348 (GRCm39) |
splice site |
probably null |
|
|
R6702:Zfp811
|
UTSW |
17 |
33,016,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6714:Zfp811
|
UTSW |
17 |
33,016,736 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6826:Zfp811
|
UTSW |
17 |
33,016,762 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6983:Zfp811
|
UTSW |
17 |
33,016,406 (GRCm39) |
nonsense |
probably null |
|
|
R7276:Zfp811
|
UTSW |
17 |
33,017,755 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7343:Zfp811
|
UTSW |
17 |
33,016,487 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7432:Zfp811
|
UTSW |
17 |
33,017,733 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R7523:Zfp811
|
UTSW |
17 |
33,016,726 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7894:Zfp811
|
UTSW |
17 |
33,017,821 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8737:Zfp811
|
UTSW |
17 |
33,017,197 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8962:Zfp811
|
UTSW |
17 |
33,017,622 (GRCm39) |
missense |
probably benign |
|
|
R8987:Zfp811
|
UTSW |
17 |
33,017,801 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9612:Zfp811
|
UTSW |
17 |
33,017,740 (GRCm39) |
missense |
probably benign |
0.33 |
|
| Posted On |
2016-08-02 |
Incidental Mutation