Incidental Mutation 'IGL03245:Cuedc1'
| ID |
414389 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Cuedc1
|
| Ensembl Gene |
ENSMUSG00000018378 |
| Gene Name |
CUE domain containing 1 |
| Synonyms |
C330016O16Rik |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
IGL03245
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
11 |
| Chromosomal Location |
87989972-88084966 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to C
at 88068088 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000120867
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000018522]
[ENSMUST00000154812]
|
| AlphaFold |
Q8R3V6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000018522
|
| SMART Domains |
Protein: ENSMUSP00000018522
Gene: ENSMUSG00000018378
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
33 |
N/A |
INTRINSIC |
|
CUE
|
50 |
92 |
6.55e-15 |
SMART |
|
low complexity region
|
94 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
121 |
136 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
222 |
N/A |
INTRINSIC |
|
low complexity region
|
331 |
340 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000133149
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000154812
|
| SMART Domains |
Protein: ENSMUSP00000120867
Gene: ENSMUSG00000018378
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
33 |
N/A |
INTRINSIC |
|
CUE
|
50 |
92 |
6.55e-15 |
SMART |
|
low complexity region
|
94 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
121 |
136 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
222 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 22 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Akap13 |
C |
T |
7: 75,259,500 (GRCm39) |
A708V |
probably damaging |
Het |
| Cdh3 |
A |
G |
8: 107,279,631 (GRCm39) |
N749S |
probably damaging |
Het |
| Col3a1 |
G |
A |
1: 45,370,269 (GRCm39) |
|
probably benign |
Het |
| Csmd2 |
T |
A |
4: 128,402,915 (GRCm39) |
S2334R |
probably benign |
Het |
| Cubn |
T |
C |
2: 13,360,500 (GRCm39) |
T1741A |
probably benign |
Het |
| Cutc |
T |
C |
19: 43,756,621 (GRCm39) |
S228P |
possibly damaging |
Het |
| Dnmt1 |
G |
T |
9: 20,827,056 (GRCm39) |
N1013K |
probably damaging |
Het |
| Dst |
G |
T |
1: 34,250,229 (GRCm39) |
|
probably null |
Het |
| Lamc2 |
A |
T |
1: 153,009,503 (GRCm39) |
|
probably null |
Het |
| Mettl25 |
T |
C |
10: 105,662,358 (GRCm39) |
N204S |
possibly damaging |
Het |
| Micall2 |
G |
A |
5: 139,705,014 (GRCm39) |
H107Y |
probably damaging |
Het |
| Or5d16 |
T |
A |
2: 87,773,086 (GRCm39) |
R295S |
possibly damaging |
Het |
| Or8g28 |
T |
A |
9: 39,169,294 (GRCm39) |
I225F |
probably damaging |
Het |
| Or9a7 |
A |
G |
6: 40,521,076 (GRCm39) |
V279A |
probably damaging |
Het |
| Ptger4 |
A |
T |
15: 5,264,588 (GRCm39) |
I331N |
probably damaging |
Het |
| Rad54l2 |
A |
G |
9: 106,580,827 (GRCm39) |
F898S |
probably damaging |
Het |
| Smr2 |
A |
G |
5: 88,256,709 (GRCm39) |
N129S |
probably benign |
Het |
| Tmeff2 |
T |
C |
1: 51,220,976 (GRCm39) |
F317S |
probably benign |
Het |
| Trpm6 |
A |
T |
19: 18,855,065 (GRCm39) |
E1908V |
probably damaging |
Het |
| Ugt2a3 |
G |
A |
5: 87,484,439 (GRCm39) |
P195L |
probably damaging |
Het |
| Xpo7 |
T |
A |
14: 70,925,734 (GRCm39) |
D436V |
probably damaging |
Het |
| Zfp804b |
C |
A |
5: 6,822,253 (GRCm39) |
S234I |
possibly damaging |
Het |
|
| Other mutations in Cuedc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01129:Cuedc1
|
APN |
11 |
88,074,080 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
IGL02103:Cuedc1
|
APN |
11 |
88,079,625 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02325:Cuedc1
|
APN |
11 |
88,060,999 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL03001:Cuedc1
|
APN |
11 |
88,073,315 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0242:Cuedc1
|
UTSW |
11 |
88,075,447 (GRCm39) |
splice site |
probably benign |
|
|
R0511:Cuedc1
|
UTSW |
11 |
88,074,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1013:Cuedc1
|
UTSW |
11 |
88,078,853 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1382:Cuedc1
|
UTSW |
11 |
88,068,189 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2004:Cuedc1
|
UTSW |
11 |
88,068,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5320:Cuedc1
|
UTSW |
11 |
88,068,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5381:Cuedc1
|
UTSW |
11 |
88,078,812 (GRCm39) |
splice site |
probably null |
|
|
R5782:Cuedc1
|
UTSW |
11 |
88,060,858 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6282:Cuedc1
|
UTSW |
11 |
88,074,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6918:Cuedc1
|
UTSW |
11 |
88,077,899 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7329:Cuedc1
|
UTSW |
11 |
88,060,692 (GRCm39) |
missense |
unknown |
|
|
R7985:Cuedc1
|
UTSW |
11 |
88,073,342 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8289:Cuedc1
|
UTSW |
11 |
88,073,381 (GRCm39) |
missense |
probably benign |
|
|
R9632:Cuedc1
|
UTSW |
11 |
88,060,955 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Posted On |
2016-08-02 |
Incidental Mutation