Incidental Mutation 'R7381:Tanc1'
| ID |
572689 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tanc1
|
| Ensembl Gene |
ENSMUSG00000035168 |
| Gene Name |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 |
| Synonyms |
1200003E16Rik |
| MMRRC Submission |
045463-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7381 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
59442386-59676493 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 59615670 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Serine
at position 226
(T226S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000123345
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037526]
[ENSMUST00000112568]
[ENSMUST00000139863]
|
| AlphaFold |
Q0VGY8 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000037526
AA Change: T226S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000036003
Gene: ENSMUSG00000035168
AA Change: T226S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
439 |
451 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
475 |
N/A |
INTRINSIC |
|
ANK
|
893 |
925 |
1.06e3 |
SMART |
|
ANK
|
929 |
960 |
2.43e3 |
SMART |
|
ANK
|
964 |
993 |
1.12e-3 |
SMART |
|
Blast:ANK
|
997 |
1028 |
7e-12 |
BLAST |
|
ANK
|
1037 |
1066 |
1.78e3 |
SMART |
|
ANK
|
1075 |
1104 |
2.34e-1 |
SMART |
|
ANK
|
1108 |
1137 |
3.71e-4 |
SMART |
|
ANK
|
1141 |
1170 |
1.51e-4 |
SMART |
|
ANK
|
1174 |
1203 |
4.89e-4 |
SMART |
|
ANK
|
1207 |
1236 |
3.01e-4 |
SMART |
|
ANK
|
1240 |
1269 |
1.99e2 |
SMART |
|
TPR
|
1286 |
1319 |
7.49e1 |
SMART |
|
TPR
|
1333 |
1366 |
2.35e-1 |
SMART |
|
TPR
|
1367 |
1400 |
6.29e-2 |
SMART |
|
low complexity region
|
1416 |
1432 |
N/A |
INTRINSIC |
|
low complexity region
|
1454 |
1483 |
N/A |
INTRINSIC |
|
low complexity region
|
1656 |
1686 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000112568
AA Change: T226S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000108187
Gene: ENSMUSG00000035168
AA Change: T226S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
444 |
N/A |
INTRINSIC |
|
low complexity region
|
448 |
468 |
N/A |
INTRINSIC |
|
ANK
|
886 |
918 |
1.06e3 |
SMART |
|
ANK
|
922 |
953 |
2.43e3 |
SMART |
|
ANK
|
957 |
986 |
1.12e-3 |
SMART |
|
Blast:ANK
|
990 |
1021 |
7e-12 |
BLAST |
|
ANK
|
1030 |
1059 |
1.78e3 |
SMART |
|
ANK
|
1068 |
1097 |
2.34e-1 |
SMART |
|
ANK
|
1101 |
1130 |
3.71e-4 |
SMART |
|
ANK
|
1134 |
1163 |
1.51e-4 |
SMART |
|
ANK
|
1167 |
1196 |
4.89e-4 |
SMART |
|
ANK
|
1200 |
1229 |
3.01e-4 |
SMART |
|
ANK
|
1233 |
1262 |
1.99e2 |
SMART |
|
TPR
|
1279 |
1312 |
7.49e1 |
SMART |
|
TPR
|
1326 |
1359 |
2.35e-1 |
SMART |
|
TPR
|
1360 |
1393 |
6.29e-2 |
SMART |
|
low complexity region
|
1409 |
1425 |
N/A |
INTRINSIC |
|
low complexity region
|
1447 |
1476 |
N/A |
INTRINSIC |
|
low complexity region
|
1649 |
1679 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000139863
AA Change: T226S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000123345
Gene: ENSMUSG00000035168
AA Change: T226S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
439 |
451 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
475 |
N/A |
INTRINSIC |
|
ANK
|
893 |
925 |
1.06e3 |
SMART |
|
ANK
|
929 |
960 |
2.43e3 |
SMART |
|
ANK
|
964 |
993 |
1.12e-3 |
SMART |
|
Blast:ANK
|
997 |
1028 |
7e-12 |
BLAST |
|
ANK
|
1037 |
1066 |
1.78e3 |
SMART |
|
ANK
|
1075 |
1104 |
2.34e-1 |
SMART |
|
ANK
|
1108 |
1137 |
3.71e-4 |
SMART |
|
ANK
|
1141 |
1170 |
1.51e-4 |
SMART |
|
ANK
|
1174 |
1203 |
4.89e-4 |
SMART |
|
ANK
|
1207 |
1236 |
3.01e-4 |
SMART |
|
ANK
|
1240 |
1269 |
1.99e2 |
SMART |
|
TPR
|
1286 |
1319 |
7.49e1 |
SMART |
|
TPR
|
1333 |
1366 |
2.35e-1 |
SMART |
|
TPR
|
1367 |
1400 |
6.29e-2 |
SMART |
|
low complexity region
|
1416 |
1432 |
N/A |
INTRINSIC |
|
low complexity region
|
1454 |
1483 |
N/A |
INTRINSIC |
|
low complexity region
|
1656 |
1686 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.2%
|
| Validation Efficiency |
98% (88/90) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap vector exhibit decreased spine density in the CA3 region and impaired spatial memory. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930550C14Rik |
T |
C |
9: 53,323,122 (GRCm39) |
Y53H |
probably damaging |
Het |
| Abca8a |
A |
T |
11: 109,920,913 (GRCm39) |
|
probably null |
Het |
| Acads |
C |
A |
5: 115,249,057 (GRCm39) |
Q365H |
probably damaging |
Het |
| Acsm3 |
A |
G |
7: 119,380,049 (GRCm39) |
D462G |
probably damaging |
Het |
| Adam39 |
T |
A |
8: 41,279,000 (GRCm39) |
C464S |
probably damaging |
Het |
| Adgra3 |
A |
G |
5: 50,216,116 (GRCm39) |
M1T |
probably null |
Het |
| AI182371 |
T |
C |
2: 34,975,371 (GRCm39) |
Y276C |
probably damaging |
Het |
| Ank2 |
T |
A |
3: 126,730,277 (GRCm39) |
H719L |
possibly damaging |
Het |
| Ano7 |
G |
A |
1: 93,323,057 (GRCm39) |
V466I |
probably benign |
Het |
| Art5 |
A |
G |
7: 101,747,377 (GRCm39) |
L134P |
probably damaging |
Het |
| Atcay |
A |
G |
10: 81,046,431 (GRCm39) |
Y298H |
possibly damaging |
Het |
| Atp1a4 |
A |
T |
1: 172,067,682 (GRCm39) |
F527Y |
possibly damaging |
Het |
| Bpifb2 |
A |
T |
2: 153,734,268 (GRCm39) |
M428L |
probably benign |
Het |
| Brinp2 |
A |
C |
1: 158,073,913 (GRCm39) |
V736G |
probably benign |
Het |
| Cdc5l |
C |
T |
17: 45,722,849 (GRCm39) |
A437T |
probably benign |
Het |
| Cdx2 |
G |
A |
5: 147,243,440 (GRCm39) |
P118L |
possibly damaging |
Het |
| Chpt1 |
G |
A |
10: 88,311,193 (GRCm39) |
|
probably null |
Het |
| Creb3l2 |
T |
A |
6: 37,312,783 (GRCm39) |
E417V |
probably damaging |
Het |
| Csnk2a1 |
A |
G |
2: 152,100,614 (GRCm39) |
T129A |
probably benign |
Het |
| Dennd6b |
A |
T |
15: 89,070,376 (GRCm39) |
L431Q |
possibly damaging |
Het |
| Dgkz |
C |
T |
2: 91,775,180 (GRCm39) |
A260T |
probably benign |
Het |
| Dhx34 |
T |
A |
7: 15,949,373 (GRCm39) |
T352S |
probably benign |
Het |
| Elp4 |
C |
T |
2: 105,622,652 (GRCm39) |
R349Q |
not run |
Het |
| Emsy |
A |
C |
7: 98,240,010 (GRCm39) |
F1228V |
probably damaging |
Het |
| Eps8l1 |
T |
A |
7: 4,473,437 (GRCm39) |
|
probably null |
Het |
| Faf1 |
T |
A |
4: 109,719,134 (GRCm39) |
D413E |
probably damaging |
Het |
| Fat3 |
T |
C |
9: 16,158,283 (GRCm39) |
Y1109C |
probably damaging |
Het |
| Fbp1 |
T |
C |
13: 63,012,867 (GRCm39) |
K314E |
probably benign |
Het |
| Fbxl20 |
A |
G |
11: 97,981,614 (GRCm39) |
V358A |
probably benign |
Het |
| Fbxo34 |
C |
G |
14: 47,767,992 (GRCm39) |
R502G |
probably benign |
Het |
| Fxr2 |
G |
A |
11: 69,532,875 (GRCm39) |
C151Y |
possibly damaging |
Het |
| Garin5b |
C |
A |
7: 4,760,681 (GRCm39) |
R677L |
|
Het |
| Gja8 |
T |
C |
3: 96,827,338 (GRCm39) |
D108G |
probably benign |
Het |
| Gm10722 |
C |
A |
9: 3,001,235 (GRCm39) |
L104I |
probably benign |
Het |
| Grsf1 |
A |
G |
5: 88,813,666 (GRCm39) |
V361A |
probably benign |
Het |
| Gsap |
T |
A |
5: 21,431,785 (GRCm39) |
I228N |
probably damaging |
Het |
| Hagh |
T |
C |
17: 25,075,686 (GRCm39) |
I131T |
probably damaging |
Het |
| Heca |
A |
T |
10: 17,791,272 (GRCm39) |
Y261* |
probably null |
Het |
| Hipk3 |
A |
G |
2: 104,269,696 (GRCm39) |
F498L |
probably damaging |
Het |
| Hps4 |
T |
A |
5: 112,523,324 (GRCm39) |
I614N |
possibly damaging |
Het |
| Icam1 |
T |
C |
9: 20,938,886 (GRCm39) |
S450P |
probably benign |
Het |
| Il22 |
G |
A |
10: 118,041,069 (GRCm39) |
M58I |
possibly damaging |
Het |
| Khdrbs2 |
T |
A |
1: 32,372,883 (GRCm39) |
S186T |
not run |
Het |
| Kif16b |
A |
G |
2: 142,699,343 (GRCm39) |
F79S |
probably damaging |
Het |
| Kntc1 |
C |
A |
5: 123,948,971 (GRCm39) |
F1905L |
probably benign |
Het |
| Liat1 |
A |
T |
11: 75,893,833 (GRCm39) |
D70V |
probably damaging |
Het |
| Lrp1b |
C |
T |
2: 40,692,929 (GRCm39) |
G3423D |
|
Het |
| Lrp5 |
G |
T |
19: 3,643,588 (GRCm39) |
Q1346K |
probably benign |
Het |
| Map3k21 |
A |
C |
8: 126,671,717 (GRCm39) |
T1002P |
possibly damaging |
Het |
| Mdga2 |
G |
T |
12: 66,615,670 (GRCm39) |
R646S |
probably benign |
Het |
| Mex3b |
G |
T |
7: 82,518,073 (GRCm39) |
M129I |
possibly damaging |
Het |
| Mfsd10 |
G |
T |
5: 34,793,770 (GRCm39) |
N85K |
probably damaging |
Het |
| Mios |
A |
G |
6: 8,216,064 (GRCm39) |
D420G |
probably damaging |
Het |
| Mogs |
C |
A |
6: 83,092,613 (GRCm39) |
P18T |
unknown |
Het |
| Mrgpre |
A |
G |
7: 143,335,150 (GRCm39) |
C118R |
probably damaging |
Het |
| Muc4 |
A |
T |
16: 32,601,285 (GRCm39) |
H1321L |
|
Het |
| Nkapl |
T |
C |
13: 21,651,759 (GRCm39) |
K285E |
probably damaging |
Het |
| Nphp4 |
C |
T |
4: 152,583,460 (GRCm39) |
P200S |
possibly damaging |
Het |
| Piezo1 |
A |
G |
8: 123,228,397 (GRCm39) |
F297L |
|
Het |
| Pkhd1 |
T |
G |
1: 20,271,197 (GRCm39) |
S3119R |
probably damaging |
Het |
| Pla2g15 |
G |
A |
8: 106,889,576 (GRCm39) |
V283I |
probably benign |
Het |
| Ppp1r13l |
T |
A |
7: 19,102,786 (GRCm39) |
|
probably null |
Het |
| Prex1 |
A |
G |
2: 166,429,047 (GRCm39) |
Y849H |
probably damaging |
Het |
| Psg27 |
C |
A |
7: 18,301,008 (GRCm39) |
W15L |
probably benign |
Het |
| Ptar1 |
A |
T |
19: 23,686,334 (GRCm39) |
|
probably null |
Het |
| Ptpn6 |
G |
A |
6: 124,705,135 (GRCm39) |
R264C |
probably damaging |
Het |
| Ptprb |
A |
G |
10: 116,177,038 (GRCm39) |
I988V |
probably benign |
Het |
| Ptpro |
G |
A |
6: 137,376,559 (GRCm39) |
V680I |
possibly damaging |
Het |
| Rnf170 |
C |
T |
8: 26,613,876 (GRCm39) |
P28S |
probably benign |
Het |
| Rnpepl1 |
A |
G |
1: 92,846,917 (GRCm39) |
S580G |
possibly damaging |
Het |
| Rtel1 |
C |
T |
2: 180,972,608 (GRCm39) |
R29* |
probably null |
Het |
| Rtkn |
T |
C |
6: 83,128,726 (GRCm39) |
L26P |
probably damaging |
Het |
| Sdk2 |
A |
C |
11: 113,729,315 (GRCm39) |
S1087R |
probably damaging |
Het |
| Sema7a |
C |
T |
9: 57,860,852 (GRCm39) |
P71L |
probably benign |
Het |
| Sgpp1 |
C |
T |
12: 75,763,038 (GRCm39) |
C381Y |
probably damaging |
Het |
| Sis |
A |
T |
3: 72,820,625 (GRCm39) |
|
probably null |
Het |
| Slc24a5 |
A |
C |
2: 124,910,869 (GRCm39) |
D100A |
probably benign |
Het |
| Slc25a23 |
A |
T |
17: 57,360,587 (GRCm39) |
I251K |
probably damaging |
Het |
| Slc6a5 |
T |
A |
7: 49,579,804 (GRCm39) |
L394H |
probably damaging |
Het |
| Slc7a4 |
A |
T |
16: 17,392,920 (GRCm39) |
M293K |
probably damaging |
Het |
| Syne2 |
T |
A |
12: 75,973,263 (GRCm39) |
S1089T |
probably benign |
Het |
| Tdrd6 |
T |
C |
17: 43,936,984 (GRCm39) |
T1355A |
probably benign |
Het |
| Tmem101 |
A |
G |
11: 102,044,176 (GRCm39) |
M237T |
possibly damaging |
Het |
| Ttn |
G |
A |
2: 76,749,359 (GRCm39) |
H3897Y |
possibly damaging |
Het |
| Tubb4a |
C |
T |
17: 57,387,698 (GRCm39) |
V443M |
unknown |
Het |
| Ucp2 |
G |
A |
7: 100,147,576 (GRCm39) |
R185H |
possibly damaging |
Het |
| Vmn1r116 |
G |
T |
7: 20,606,436 (GRCm39) |
E86* |
probably null |
Het |
| Vmn2r37 |
T |
C |
7: 9,213,032 (GRCm39) |
E530G |
probably benign |
Het |
| Vwa8 |
A |
G |
14: 79,333,125 (GRCm39) |
T1293A |
probably benign |
Het |
| Zfc3h1 |
T |
A |
10: 115,260,535 (GRCm39) |
Y1711N |
probably benign |
Het |
| Zfp873 |
A |
T |
10: 81,896,805 (GRCm39) |
E512V |
probably damaging |
Het |
| Zfyve16 |
T |
A |
13: 92,657,654 (GRCm39) |
K752N |
probably damaging |
Het |
| Zhx1 |
T |
C |
15: 57,916,561 (GRCm39) |
N562D |
possibly damaging |
Het |
|
| Other mutations in Tanc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00340:Tanc1
|
APN |
2 |
59,621,185 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL00484:Tanc1
|
APN |
2 |
59,623,520 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00688:Tanc1
|
APN |
2 |
59,645,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00765:Tanc1
|
APN |
2 |
59,636,645 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01576:Tanc1
|
APN |
2 |
59,628,079 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01590:Tanc1
|
APN |
2 |
59,615,817 (GRCm39) |
missense |
probably benign |
|
|
IGL02016:Tanc1
|
APN |
2 |
59,673,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02373:Tanc1
|
APN |
2 |
59,626,372 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02539:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02540:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02541:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02543:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02559:Tanc1
|
APN |
2 |
59,554,998 (GRCm39) |
splice site |
probably benign |
|
|
IGL02626:Tanc1
|
APN |
2 |
59,630,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02669:Tanc1
|
APN |
2 |
59,630,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02902:Tanc1
|
APN |
2 |
59,623,431 (GRCm39) |
splice site |
probably benign |
|
|
Oreja
|
UTSW |
2 |
59,622,148 (GRCm39) |
synonymous |
silent |
|
|
R0178:Tanc1
|
UTSW |
2 |
59,665,791 (GRCm39) |
nonsense |
probably null |
|
|
R0347:Tanc1
|
UTSW |
2 |
59,673,335 (GRCm39) |
missense |
probably benign |
|
|
R0570:Tanc1
|
UTSW |
2 |
59,626,382 (GRCm39) |
splice site |
probably benign |
|
|
R0660:Tanc1
|
UTSW |
2 |
59,674,228 (GRCm39) |
nonsense |
probably null |
|
|
R0664:Tanc1
|
UTSW |
2 |
59,674,228 (GRCm39) |
nonsense |
probably null |
|
|
R0898:Tanc1
|
UTSW |
2 |
59,621,132 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1333:Tanc1
|
UTSW |
2 |
59,673,835 (GRCm39) |
missense |
probably benign |
|
|
R1575:Tanc1
|
UTSW |
2 |
59,621,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1608:Tanc1
|
UTSW |
2 |
59,628,038 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1616:Tanc1
|
UTSW |
2 |
59,615,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1703:Tanc1
|
UTSW |
2 |
59,673,365 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1727:Tanc1
|
UTSW |
2 |
59,621,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1809:Tanc1
|
UTSW |
2 |
59,630,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1812:Tanc1
|
UTSW |
2 |
59,622,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1925:Tanc1
|
UTSW |
2 |
59,555,095 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R1951:Tanc1
|
UTSW |
2 |
59,622,156 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2174:Tanc1
|
UTSW |
2 |
59,674,177 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2228:Tanc1
|
UTSW |
2 |
59,555,068 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2267:Tanc1
|
UTSW |
2 |
59,667,563 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4191:Tanc1
|
UTSW |
2 |
59,669,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4476:Tanc1
|
UTSW |
2 |
59,672,340 (GRCm39) |
splice site |
probably null |
|
|
R4632:Tanc1
|
UTSW |
2 |
59,626,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4825:Tanc1
|
UTSW |
2 |
59,529,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4982:Tanc1
|
UTSW |
2 |
59,630,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5338:Tanc1
|
UTSW |
2 |
59,626,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5657:Tanc1
|
UTSW |
2 |
59,665,051 (GRCm39) |
splice site |
probably null |
|
|
R5672:Tanc1
|
UTSW |
2 |
59,602,697 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5703:Tanc1
|
UTSW |
2 |
59,626,341 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5707:Tanc1
|
UTSW |
2 |
59,588,874 (GRCm39) |
missense |
probably benign |
|
|
R5778:Tanc1
|
UTSW |
2 |
59,529,691 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5795:Tanc1
|
UTSW |
2 |
59,637,926 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R5831:Tanc1
|
UTSW |
2 |
59,615,685 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5849:Tanc1
|
UTSW |
2 |
59,630,248 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5912:Tanc1
|
UTSW |
2 |
59,622,030 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5944:Tanc1
|
UTSW |
2 |
59,667,564 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6057:Tanc1
|
UTSW |
2 |
59,647,837 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6142:Tanc1
|
UTSW |
2 |
59,663,566 (GRCm39) |
nonsense |
probably null |
|
|
R6179:Tanc1
|
UTSW |
2 |
59,673,320 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6185:Tanc1
|
UTSW |
2 |
59,621,929 (GRCm39) |
splice site |
probably null |
|
|
R6192:Tanc1
|
UTSW |
2 |
59,669,305 (GRCm39) |
splice site |
probably null |
|
|
R6196:Tanc1
|
UTSW |
2 |
59,674,366 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6197:Tanc1
|
UTSW |
2 |
59,674,366 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6230:Tanc1
|
UTSW |
2 |
59,672,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6275:Tanc1
|
UTSW |
2 |
59,673,854 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6415:Tanc1
|
UTSW |
2 |
59,667,458 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6480:Tanc1
|
UTSW |
2 |
59,637,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6578:Tanc1
|
UTSW |
2 |
59,626,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6786:Tanc1
|
UTSW |
2 |
59,622,150 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7006:Tanc1
|
UTSW |
2 |
59,626,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7133:Tanc1
|
UTSW |
2 |
59,627,953 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7422:Tanc1
|
UTSW |
2 |
59,636,688 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8392:Tanc1
|
UTSW |
2 |
59,636,651 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8692:Tanc1
|
UTSW |
2 |
59,673,989 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8730:Tanc1
|
UTSW |
2 |
59,601,590 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8731:Tanc1
|
UTSW |
2 |
59,673,596 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8813:Tanc1
|
UTSW |
2 |
59,630,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8815:Tanc1
|
UTSW |
2 |
59,621,185 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8933:Tanc1
|
UTSW |
2 |
59,615,800 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9015:Tanc1
|
UTSW |
2 |
59,622,224 (GRCm39) |
missense |
probably benign |
|
|
R9042:Tanc1
|
UTSW |
2 |
59,673,766 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9154:Tanc1
|
UTSW |
2 |
59,630,132 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9269:Tanc1
|
UTSW |
2 |
59,630,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9283:Tanc1
|
UTSW |
2 |
59,630,174 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9380:Tanc1
|
UTSW |
2 |
59,665,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9422:Tanc1
|
UTSW |
2 |
59,637,933 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9428:Tanc1
|
UTSW |
2 |
59,601,548 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9694:Tanc1
|
UTSW |
2 |
59,626,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF028:Tanc1
|
UTSW |
2 |
59,673,613 (GRCm39) |
small deletion |
probably benign |
|
|
RF049:Tanc1
|
UTSW |
2 |
59,673,613 (GRCm39) |
small deletion |
probably benign |
|
|
X0063:Tanc1
|
UTSW |
2 |
59,674,324 (GRCm39) |
nonsense |
probably null |
|
|
X0064:Tanc1
|
UTSW |
2 |
59,674,456 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Tanc1
|
UTSW |
2 |
59,602,873 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Tanc1
|
UTSW |
2 |
59,622,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Tanc1
|
UTSW |
2 |
59,621,231 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CAGTTTATTTCCCCTGATAAGCAAC -3'
(R):5'- CATTATGAGCGAGCCAGAGC -3'
Sequencing Primer
(F):5'- tgtgtgtgtgtgtgtgtg -3'
(R):5'- ATCTCCGGCTGAGGGTTC -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation