Mutagenetix > Incidental Mutation

Incidental Mutation 'R0321:Muc5b'

66356

Institutional Source

Beutler Lab

Gene Symbol

Muc5b

Ensembl Gene

ENSMUSG00000066108

Gene Name

mucin 5, subtype B, tracheobronchial

Synonyms

MUC5, 2300002I04Rik, MUC9

MMRRC Submission

038531-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.159) question?

Stock #

R0321 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

141392807-141426821 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 141415972 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 2973 (S2973P)

Ref Sequence

ENSEMBL: ENSMUSP00000128276 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000165147]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000165147
AA Change: S2973P

PolyPhen 2 Score 0.191 (Sensitivity: 0.92; Specificity: 0.87)

SMART Domains

Protein: ENSMUSP00000128276
Gene: ENSMUSG00000066108
AA Change: S2973P

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
VWD	73	228	1.12e-25	SMART
C8	267	330	7.26e-8	SMART
Pfam:TIL	333	389	1.1e-13	PFAM
VWC	391	459	1.35e-1	SMART
VWD	418	582	2.87e-37	SMART
C8	619	693	2.53e-30	SMART
Pfam:TIL	699	756	2.6e-10	PFAM
VWC	758	823	1.26e0	SMART
VWC	861	930	1.58e-7	SMART
VWD	888	1048	3e-40	SMART
C8	1084	1158	3.75e-33	SMART
low complexity region	1314	1328	N/A	INTRINSIC
Pfam:Mucin2_WxxW	1345	1432	6.7e-27	PFAM
low complexity region	1447	1468	N/A	INTRINSIC
low complexity region	1498	1517	N/A	INTRINSIC
low complexity region	1543	1558	N/A	INTRINSIC
Pfam:Mucin2_WxxW	1574	1663	2.1e-26	PFAM
low complexity region	1678	1693	N/A	INTRINSIC
low complexity region	1728	1745	N/A	INTRINSIC
low complexity region	1778	1831	N/A	INTRINSIC
Pfam:Mucin2_WxxW	1870	1959	2.7e-26	PFAM
low complexity region	1967	1990	N/A	INTRINSIC
low complexity region	2024	2041	N/A	INTRINSIC
low complexity region	2074	2127	N/A	INTRINSIC
Pfam:Mucin2_WxxW	2184	2273	2.1e-26	PFAM
low complexity region	2281	2304	N/A	INTRINSIC
low complexity region	2338	2355	N/A	INTRINSIC
low complexity region	2388	2441	N/A	INTRINSIC
Pfam:Mucin2_WxxW	2498	2587	2.1e-26	PFAM
low complexity region	2596	2618	N/A	INTRINSIC
low complexity region	2623	2654	N/A	INTRINSIC
low complexity region	2660	2681	N/A	INTRINSIC
Pfam:Mucin2_WxxW	2687	2776	3.8e-25	PFAM
low complexity region	2781	2796	N/A	INTRINSIC
low complexity region	2958	3009	N/A	INTRINSIC
Pfam:Mucin2_WxxW	3066	3155	2.6e-26	PFAM
low complexity region	3220	3237	N/A	INTRINSIC
low complexity region	3270	3317	N/A	INTRINSIC
Pfam:Mucin2_WxxW	3380	3469	3.4e-26	PFAM
low complexity region	3509	3529	N/A	INTRINSIC
low complexity region	3546	3562	N/A	INTRINSIC
low complexity region	3568	3591	N/A	INTRINSIC
Pfam:Mucin2_WxxW	3624	3713	2.6e-27	PFAM
Pfam:Mucin2_WxxW	3778	3867	3.2e-24	PFAM
low complexity region	3883	3900	N/A	INTRINSIC
low complexity region	3910	3934	N/A	INTRINSIC
low complexity region	3959	3976	N/A	INTRINSIC
low complexity region	4033	4053	N/A	INTRINSIC
VWD	4111	4283	6.75e-34	SMART
C8	4336	4403	4.26e-14	SMART
VWC	4461	4530	7.06e-5	SMART
VWC	4570	4631	6.53e-9	SMART
CT	4708	4790	2.93e-26	SMART

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 99.2%
3x: 98.4%
10x: 96.5%
20x: 93.7%

Validation Efficiency

100% (79/79)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010]
PHENOTYPE: Mice homozygous for a knock-out allele accumulate materials in the upper and lower airways leading to chronic infection and inflammation that does not resolve and results in premature death. Macrophage function is impaired. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 73 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4921509C19Rik	T	C	2: 151,314,620 (GRCm39)	T353A	probably benign	Het
4933402N03Rik	T	A	7: 130,747,956 (GRCm39)	Y12F	probably benign	Het
Acbd3	T	G	1: 180,579,870 (GRCm39)	F505V	probably damaging	Het
Acod1	T	C	14: 103,292,565 (GRCm39)	V363A	probably benign	Het
Adam28	T	C	14: 68,855,200 (GRCm39)	Q647R	probably damaging	Het
Akr1c18	T	A	13: 4,185,243 (GRCm39)	L296F	probably damaging	Het
Ap1b1	G	A	11: 4,982,464 (GRCm39)	A588T	probably benign	Het
Armc8	A	T	9: 99,415,230 (GRCm39)	I150K	probably damaging	Het
Bahcc1	T	C	11: 120,164,251 (GRCm39)		probably null	Het
Bltp1	T	C	3: 36,960,937 (GRCm39)		probably null	Het
Carmil3	C	A	14: 55,739,698 (GRCm39)	D928E	possibly damaging	Het
Ccrl2	T	C	9: 110,885,279 (GRCm39)	N73S	probably damaging	Het
Cdk9	C	A	2: 32,602,698 (GRCm39)		probably benign	Het
Cel	G	T	2: 28,451,160 (GRCm39)	Q66K	probably benign	Het
D930028M14Rik	T	A	7: 24,854,991 (GRCm39)		noncoding transcript	Het
Dgka	G	C	10: 128,556,952 (GRCm39)		probably benign	Het
Dlg1	T	C	16: 31,676,854 (GRCm39)	V801A	probably damaging	Het
Dnah10	A	G	5: 124,900,416 (GRCm39)	D3834G	probably benign	Het
Dnajc15	C	T	14: 78,112,273 (GRCm39)	A23T	possibly damaging	Het
Ell2	T	A	13: 75,910,007 (GRCm39)	L119Q	probably damaging	Het
Epha2	T	C	4: 141,035,716 (GRCm39)	W51R	probably damaging	Het
F10	T	C	8: 13,103,413 (GRCm39)	F266L	possibly damaging	Het
Fam110a	T	C	2: 151,812,587 (GRCm39)	N61S	probably benign	Het
Fam83c	C	T	2: 155,671,620 (GRCm39)	S605N	probably benign	Het
Fbxw15	C	T	9: 109,394,453 (GRCm39)	V121I	probably benign	Het
Gart	G	A	16: 91,419,925 (GRCm39)		probably benign	Het
Gfi1b	A	G	2: 28,503,897 (GRCm39)	F101S	probably damaging	Het
Gimap5	C	G	6: 48,727,449 (GRCm39)		probably benign	Het
Gpr180	T	C	14: 118,385,699 (GRCm39)		probably null	Het
Gsn	T	C	2: 35,180,408 (GRCm39)	F188L	probably benign	Het
Hivep3	T	A	4: 119,952,788 (GRCm39)	I368N	possibly damaging	Het
Itih3	T	A	14: 30,634,063 (GRCm39)	I153F	probably damaging	Het
Kdm8	A	T	7: 125,060,178 (GRCm39)	Q360L	probably damaging	Het
Lars1	T	C	18: 42,335,697 (GRCm39)	K1140E	probably damaging	Het
Mocs1	A	G	17: 49,740,286 (GRCm39)	Y71C	probably damaging	Het
Mroh5	C	T	15: 73,661,892 (GRCm39)	G433E	probably damaging	Het
Mrpl45	T	A	11: 97,217,764 (GRCm39)		probably benign	Het
Mtcl1	T	A	17: 66,686,426 (GRCm39)	T827S	probably damaging	Het
Mynn	T	C	3: 30,661,706 (GRCm39)	S263P	probably benign	Het
Myo1f	A	C	17: 33,811,986 (GRCm39)	D595A	probably benign	Het
Necab1	A	T	4: 14,960,083 (GRCm39)	I288N	probably damaging	Het
Nutm2	T	G	13: 50,626,991 (GRCm39)	M382R	probably damaging	Het
Oprm1	T	C	10: 6,779,183 (GRCm39)	S131P	probably damaging	Het
Pcsk9	A	G	4: 106,301,891 (GRCm39)	S619P	probably benign	Het
Phkg1	A	T	5: 129,898,365 (GRCm39)	M1K	probably null	Het
Pigc	C	T	1: 161,798,668 (GRCm39)	Q217*	probably null	Het
Pik3r4	T	A	9: 105,525,906 (GRCm39)	F259I	probably damaging	Het
Pkdcc	A	T	17: 83,529,541 (GRCm39)		probably benign	Het
Pnpla5	G	T	15: 84,004,920 (GRCm39)	L144M	probably damaging	Het
Prtg	A	T	9: 72,755,307 (GRCm39)	I259F	possibly damaging	Het
Prune2	T	G	19: 17,098,291 (GRCm39)	L1265R	possibly damaging	Het
Prune2	C	T	19: 17,099,818 (GRCm39)	A1774V	probably benign	Het
Rcn3	A	G	7: 44,738,139 (GRCm39)		probably benign	Het
Rnf213	C	T	11: 119,328,931 (GRCm39)	Q2067*	probably null	Het
Sec14l1	T	A	11: 117,041,568 (GRCm39)		probably benign	Het
Serpinb3a	C	T	1: 106,975,212 (GRCm39)	W198*	probably null	Het
Smpdl3b	A	T	4: 132,468,755 (GRCm39)	V154E	probably damaging	Het
Spag17	T	C	3: 100,008,719 (GRCm39)	S1950P	probably damaging	Het
Sprr1a	T	C	3: 92,391,609 (GRCm39)	T131A	probably benign	Het
Tatdn2	T	G	6: 113,686,462 (GRCm39)	L690W	probably damaging	Het
Tbc1d1	T	C	5: 64,496,937 (GRCm39)	F864L	probably damaging	Het
Tmem8b	C	A	4: 43,674,444 (GRCm39)	R243S	probably damaging	Het
Tnfrsf11a	T	A	1: 105,772,583 (GRCm39)	C623*	probably null	Het
Tprg1l	T	C	4: 154,243,812 (GRCm39)	N115D	probably damaging	Het
Ube2t	C	T	1: 134,895,538 (GRCm39)	A4V	possibly damaging	Het
Vps41	G	A	13: 19,026,465 (GRCm39)		probably benign	Het
Wdr17	C	T	8: 55,149,303 (GRCm39)		probably null	Het
Wwc1	G	A	11: 35,732,637 (GRCm39)	Q1024*	probably null	Het
Zfand5	T	A	19: 21,253,879 (GRCm39)	N27K	probably damaging	Het
Zfp142	A	T	1: 74,608,873 (GRCm39)	C1641S	probably damaging	Het
Zfyve16	A	G	13: 92,629,042 (GRCm39)	I1465T	probably damaging	Het
Zswim1	G	A	2: 164,667,947 (GRCm39)	G400S	probably benign	Het
Zswim3	C	T	2: 164,662,279 (GRCm39)	A253V	possibly damaging	Het

Other mutations in Muc5b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00586:Muc5b	APN	7	141,395,129 (GRCm39)	missense	unknown
IGL00677:Muc5b	APN	7	141,411,631 (GRCm39)	nonsense	probably null
IGL00740:Muc5b	APN	7	141,409,335 (GRCm39)	missense	unknown
IGL01084:Muc5b	APN	7	141,397,186 (GRCm39)	splice site	probably benign
IGL01384:Muc5b	APN	7	141,400,555 (GRCm39)	missense	unknown
IGL01447:Muc5b	APN	7	141,416,831 (GRCm39)	missense	probably benign	0.01
IGL01510:Muc5b	APN	7	141,412,798 (GRCm39)	missense	unknown
IGL01532:Muc5b	APN	7	141,423,743 (GRCm39)	missense	possibly damaging	0.96
IGL01556:Muc5b	APN	7	141,416,977 (GRCm39)	missense	probably benign	0.01
IGL01608:Muc5b	APN	7	141,400,174 (GRCm39)	missense	unknown
IGL01884:Muc5b	APN	7	141,421,820 (GRCm39)	splice site	probably benign
IGL01943:Muc5b	APN	7	141,415,234 (GRCm39)	missense	possibly damaging	0.71
IGL02039:Muc5b	APN	7	141,424,901 (GRCm39)	missense	possibly damaging	0.96
IGL02089:Muc5b	APN	7	141,416,987 (GRCm39)	missense	probably benign	0.04
IGL02110:Muc5b	APN	7	141,401,453 (GRCm39)	nonsense	probably null
IGL02123:Muc5b	APN	7	141,417,494 (GRCm39)	missense	possibly damaging	0.68
IGL02124:Muc5b	APN	7	141,409,369 (GRCm39)	missense	unknown
IGL02141:Muc5b	APN	7	141,407,104 (GRCm39)	missense	unknown
IGL02409:Muc5b	APN	7	141,415,075 (GRCm39)	missense	possibly damaging	0.53
IGL02448:Muc5b	APN	7	141,422,226 (GRCm39)	missense	possibly damaging	0.53
IGL02503:Muc5b	APN	7	141,421,404 (GRCm39)	missense	probably benign	0.33
IGL02504:Muc5b	APN	7	141,400,177 (GRCm39)	missense	unknown
IGL02528:Muc5b	APN	7	141,417,754 (GRCm39)	missense	probably benign	0.01
IGL02534:Muc5b	APN	7	141,398,456 (GRCm39)	missense	unknown
IGL02565:Muc5b	APN	7	141,411,604 (GRCm39)	missense	unknown
IGL02630:Muc5b	APN	7	141,416,968 (GRCm39)	missense	probably benign	0.03
IGL02881:Muc5b	APN	7	141,411,449 (GRCm39)	missense	unknown
IGL02963:Muc5b	APN	7	141,418,001 (GRCm39)	missense	probably damaging	1.00
IGL03003:Muc5b	APN	7	141,417,351 (GRCm39)	missense	probably benign	0.03
IGL03013:Muc5b	APN	7	141,417,665 (GRCm39)	missense	possibly damaging	0.68
IGL03102:Muc5b	APN	7	141,416,806 (GRCm39)	missense	probably benign	0.35
IGL03114:Muc5b	APN	7	141,412,556 (GRCm39)	nonsense	probably null
IGL03150:Muc5b	APN	7	141,419,246 (GRCm39)	missense	possibly damaging	0.53
IGL03185:Muc5b	APN	7	141,416,559 (GRCm39)	missense	possibly damaging	0.83
IGL03299:Muc5b	APN	7	141,395,117 (GRCm39)	missense	unknown
IGL03336:Muc5b	APN	7	141,418,100 (GRCm39)	missense	probably damaging	1.00
IGL03370:Muc5b	APN	7	141,418,514 (GRCm39)	missense	probably benign	0.34
IGL03375:Muc5b	APN	7	141,415,699 (GRCm39)	missense	possibly damaging	0.53
IGL03393:Muc5b	APN	7	141,417,875 (GRCm39)	missense	probably benign	0.21
profligate	UTSW	7	141,411,559 (GRCm39)	nonsense	probably null
wasteful	UTSW	7	141,411,898 (GRCm39)	missense	unknown
R0045:Muc5b	UTSW	7	141,410,555 (GRCm39)	missense	unknown
R0256:Muc5b	UTSW	7	141,396,995 (GRCm39)	missense	unknown
R0256:Muc5b	UTSW	7	141,395,132 (GRCm39)	missense	unknown
R0391:Muc5b	UTSW	7	141,418,819 (GRCm39)	missense	possibly damaging	0.73
R0458:Muc5b	UTSW	7	141,418,709 (GRCm39)	missense	probably benign	0.20
R0491:Muc5b	UTSW	7	141,415,752 (GRCm39)	missense	probably benign	0.01
R0543:Muc5b	UTSW	7	141,405,522 (GRCm39)	missense	unknown
R0583:Muc5b	UTSW	7	141,410,435 (GRCm39)	nonsense	probably null
R0611:Muc5b	UTSW	7	141,416,173 (GRCm39)	missense	probably benign	0.18
R0625:Muc5b	UTSW	7	141,400,164 (GRCm39)	missense	unknown
R0655:Muc5b	UTSW	7	141,417,679 (GRCm39)	missense	probably benign	0.01
R0845:Muc5b	UTSW	7	141,404,183 (GRCm39)	splice site	probably null
R0863:Muc5b	UTSW	7	141,421,454 (GRCm39)	missense	probably benign	0.18
R0965:Muc5b	UTSW	7	141,417,539 (GRCm39)	missense	possibly damaging	0.92
R0988:Muc5b	UTSW	7	141,425,532 (GRCm39)	missense	probably benign	0.03
R1140:Muc5b	UTSW	7	141,412,733 (GRCm39)	missense	unknown
R1209:Muc5b	UTSW	7	141,411,647 (GRCm39)	missense	unknown
R1333:Muc5b	UTSW	7	141,422,144 (GRCm39)	missense	possibly damaging	0.53
R1337:Muc5b	UTSW	7	141,412,361 (GRCm39)	missense	unknown
R1385:Muc5b	UTSW	7	141,415,874 (GRCm39)	missense	probably benign	0.00
R1463:Muc5b	UTSW	7	141,412,817 (GRCm39)	missense	unknown
R1471:Muc5b	UTSW	7	141,396,971 (GRCm39)	missense	unknown
R1617:Muc5b	UTSW	7	141,417,261 (GRCm39)	nonsense	probably null
R1736:Muc5b	UTSW	7	141,412,844 (GRCm39)	missense	unknown
R1752:Muc5b	UTSW	7	141,421,488 (GRCm39)	missense	possibly damaging	0.96
R1804:Muc5b	UTSW	7	141,417,517 (GRCm39)	missense	possibly damaging	0.68
R1806:Muc5b	UTSW	7	141,419,230 (GRCm39)	missense	possibly damaging	0.68
R1895:Muc5b	UTSW	7	141,411,382 (GRCm39)	missense	unknown
R1902:Muc5b	UTSW	7	141,417,842 (GRCm39)	missense	possibly damaging	0.77
R1919:Muc5b	UTSW	7	141,399,768 (GRCm39)	missense	unknown
R1924:Muc5b	UTSW	7	141,421,960 (GRCm39)	missense	possibly damaging	0.53
R1942:Muc5b	UTSW	7	141,411,421 (GRCm39)	missense	unknown
R1959:Muc5b	UTSW	7	141,416,374 (GRCm39)	missense	possibly damaging	0.86
R1960:Muc5b	UTSW	7	141,416,374 (GRCm39)	missense	possibly damaging	0.86
R1976:Muc5b	UTSW	7	141,416,891 (GRCm39)	missense	probably benign	0.01
R2080:Muc5b	UTSW	7	141,423,491 (GRCm39)	missense	probably benign	0.33
R2178:Muc5b	UTSW	7	141,417,853 (GRCm39)	missense	possibly damaging	0.58
R2184:Muc5b	UTSW	7	141,412,601 (GRCm39)	nonsense	probably null
R2229:Muc5b	UTSW	7	141,415,381 (GRCm39)	missense	possibly damaging	0.71
R2237:Muc5b	UTSW	7	141,415,826 (GRCm39)	missense	probably benign	0.00
R2509:Muc5b	UTSW	7	141,412,798 (GRCm39)	missense	unknown
R2510:Muc5b	UTSW	7	141,412,798 (GRCm39)	missense	unknown
R2512:Muc5b	UTSW	7	141,412,813 (GRCm39)	missense	unknown
R2888:Muc5b	UTSW	7	141,415,291 (GRCm39)	missense	probably damaging	0.98
R3054:Muc5b	UTSW	7	141,417,778 (GRCm39)	missense	probably damaging	0.97
R3055:Muc5b	UTSW	7	141,417,778 (GRCm39)	missense	probably damaging	0.97
R3108:Muc5b	UTSW	7	141,412,496 (GRCm39)	missense	unknown
R3109:Muc5b	UTSW	7	141,412,496 (GRCm39)	missense	unknown
R3113:Muc5b	UTSW	7	141,399,871 (GRCm39)	missense	unknown
R3551:Muc5b	UTSW	7	141,415,072 (GRCm39)	missense	possibly damaging	0.53
R3552:Muc5b	UTSW	7	141,421,442 (GRCm39)	missense	probably benign	0.18
R3552:Muc5b	UTSW	7	141,415,072 (GRCm39)	missense	possibly damaging	0.53
R3622:Muc5b	UTSW	7	141,405,595 (GRCm39)	splice site	probably benign
R3700:Muc5b	UTSW	7	141,400,986 (GRCm39)	missense	unknown
R3734:Muc5b	UTSW	7	141,412,774 (GRCm39)	nonsense	probably null
R3785:Muc5b	UTSW	7	141,418,853 (GRCm39)	missense	possibly damaging	0.86
R3786:Muc5b	UTSW	7	141,418,853 (GRCm39)	missense	possibly damaging	0.86
R3788:Muc5b	UTSW	7	141,417,571 (GRCm39)	missense	possibly damaging	0.68
R3810:Muc5b	UTSW	7	141,417,863 (GRCm39)	missense	possibly damaging	0.58
R3834:Muc5b	UTSW	7	141,412,918 (GRCm39)	missense	unknown
R3835:Muc5b	UTSW	7	141,412,918 (GRCm39)	missense	unknown
R3850:Muc5b	UTSW	7	141,416,375 (GRCm39)	missense	possibly damaging	0.95
R3877:Muc5b	UTSW	7	141,411,289 (GRCm39)	missense	unknown
R3909:Muc5b	UTSW	7	141,403,235 (GRCm39)	missense	unknown
R3964:Muc5b	UTSW	7	141,420,705 (GRCm39)	missense	possibly damaging	0.73
R4014:Muc5b	UTSW	7	141,417,367 (GRCm39)	missense	probably benign	0.40
R4015:Muc5b	UTSW	7	141,417,367 (GRCm39)	missense	probably benign	0.40
R4017:Muc5b	UTSW	7	141,417,367 (GRCm39)	missense	probably benign	0.40
R4042:Muc5b	UTSW	7	141,418,624 (GRCm39)	missense	possibly damaging	0.92
R4200:Muc5b	UTSW	7	141,412,662 (GRCm39)	nonsense	probably null
R4230:Muc5b	UTSW	7	141,417,259 (GRCm39)	missense	probably benign	0.03
R4400:Muc5b	UTSW	7	141,415,124 (GRCm39)	missense	possibly damaging	0.92
R4455:Muc5b	UTSW	7	141,412,555 (GRCm39)	missense	unknown
R4484:Muc5b	UTSW	7	141,422,187 (GRCm39)	missense	possibly damaging	0.73
R4630:Muc5b	UTSW	7	141,411,721 (GRCm39)	missense	unknown
R4646:Muc5b	UTSW	7	141,416,377 (GRCm39)	missense	probably benign	0.34
R4658:Muc5b	UTSW	7	141,395,135 (GRCm39)	missense	unknown
R4667:Muc5b	UTSW	7	141,396,116 (GRCm39)	missense	unknown
R4690:Muc5b	UTSW	7	141,396,031 (GRCm39)	missense	unknown
R4697:Muc5b	UTSW	7	141,411,098 (GRCm39)	missense	unknown
R4711:Muc5b	UTSW	7	141,399,770 (GRCm39)	missense	unknown
R4713:Muc5b	UTSW	7	141,402,816 (GRCm39)	nonsense	probably null
R4749:Muc5b	UTSW	7	141,415,185 (GRCm39)	nonsense	probably null
R4753:Muc5b	UTSW	7	141,410,590 (GRCm39)	missense	unknown
R4782:Muc5b	UTSW	7	141,401,453 (GRCm39)	nonsense	probably null
R4795:Muc5b	UTSW	7	141,403,304 (GRCm39)	missense	unknown
R4796:Muc5b	UTSW	7	141,417,983 (GRCm39)	missense	possibly damaging	0.52
R4799:Muc5b	UTSW	7	141,401,453 (GRCm39)	nonsense	probably null
R4824:Muc5b	UTSW	7	141,417,922 (GRCm39)	missense	probably damaging	1.00
R4825:Muc5b	UTSW	7	141,422,202 (GRCm39)	missense	possibly damaging	0.96
R5068:Muc5b	UTSW	7	141,412,345 (GRCm39)	missense	unknown
R5073:Muc5b	UTSW	7	141,412,999 (GRCm39)	missense	unknown
R5074:Muc5b	UTSW	7	141,412,999 (GRCm39)	missense	unknown
R5107:Muc5b	UTSW	7	141,409,268 (GRCm39)	missense	unknown
R5152:Muc5b	UTSW	7	141,419,268 (GRCm39)	missense	possibly damaging	0.53
R5183:Muc5b	UTSW	7	141,404,547 (GRCm39)	missense	unknown
R5191:Muc5b	UTSW	7	141,412,276 (GRCm39)	missense	unknown
R5254:Muc5b	UTSW	7	141,418,277 (GRCm39)	missense	probably benign	0.09
R5320:Muc5b	UTSW	7	141,412,738 (GRCm39)	missense	unknown
R5352:Muc5b	UTSW	7	141,418,295 (GRCm39)	missense	possibly damaging	0.66
R5378:Muc5b	UTSW	7	141,415,940 (GRCm39)	missense	unknown
R5417:Muc5b	UTSW	7	141,411,781 (GRCm39)	missense	unknown
R5548:Muc5b	UTSW	7	141,417,679 (GRCm39)	missense	probably benign	0.01
R5551:Muc5b	UTSW	7	141,422,240 (GRCm39)	missense	possibly damaging	0.73
R5562:Muc5b	UTSW	7	141,400,975 (GRCm39)	missense	unknown
R5580:Muc5b	UTSW	7	141,415,084 (GRCm39)	missense	possibly damaging	0.53
R5629:Muc5b	UTSW	7	141,415,036 (GRCm39)	missense	possibly damaging	0.73
R5758:Muc5b	UTSW	7	141,412,720 (GRCm39)	missense	unknown
R5783:Muc5b	UTSW	7	141,412,165 (GRCm39)	nonsense	probably null
R5795:Muc5b	UTSW	7	141,425,478 (GRCm39)	missense	possibly damaging	0.96
R5796:Muc5b	UTSW	7	141,411,133 (GRCm39)	missense	unknown
R5797:Muc5b	UTSW	7	141,405,319 (GRCm39)	missense	unknown
R5806:Muc5b	UTSW	7	141,416,572 (GRCm39)	missense	possibly damaging	0.68
R5888:Muc5b	UTSW	7	141,412,158 (GRCm39)	missense	unknown
R5910:Muc5b	UTSW	7	141,415,048 (GRCm39)	missense	possibly damaging	0.53
R5956:Muc5b	UTSW	7	141,417,910 (GRCm39)	missense	probably damaging	0.99
R5970:Muc5b	UTSW	7	141,410,449 (GRCm39)	missense	unknown
R5990:Muc5b	UTSW	7	141,411,898 (GRCm39)	missense	unknown
R5999:Muc5b	UTSW	7	141,411,116 (GRCm39)	missense	unknown
R6001:Muc5b	UTSW	7	141,426,118 (GRCm39)	missense	possibly damaging	0.72
R6053:Muc5b	UTSW	7	141,418,445 (GRCm39)	missense	probably benign	0.07
R6073:Muc5b	UTSW	7	141,412,025 (GRCm39)	missense	unknown
R6073:Muc5b	UTSW	7	141,402,797 (GRCm39)	missense	unknown
R6112:Muc5b	UTSW	7	141,417,042 (GRCm39)	missense	probably benign	0.01
R6153:Muc5b	UTSW	7	141,415,181 (GRCm39)	missense	possibly damaging	0.71
R6164:Muc5b	UTSW	7	141,417,082 (GRCm39)	missense	possibly damaging	0.73
R6172:Muc5b	UTSW	7	141,412,513 (GRCm39)	missense	unknown
R6178:Muc5b	UTSW	7	141,410,079 (GRCm39)	missense	probably null
R6196:Muc5b	UTSW	7	141,405,333 (GRCm39)	missense	unknown
R6213:Muc5b	UTSW	7	141,421,356 (GRCm39)	missense	possibly damaging	0.92
R6213:Muc5b	UTSW	7	141,415,903 (GRCm39)	missense	probably benign	0.00
R6344:Muc5b	UTSW	7	141,416,708 (GRCm39)	missense	possibly damaging	0.62
R6400:Muc5b	UTSW	7	141,412,402 (GRCm39)	missense	unknown
R6414:Muc5b	UTSW	7	141,412,834 (GRCm39)	missense	unknown
R6521:Muc5b	UTSW	7	141,412,908 (GRCm39)	nonsense	probably null
R6658:Muc5b	UTSW	7	141,422,244 (GRCm39)	critical splice donor site	probably null
R6717:Muc5b	UTSW	7	141,411,559 (GRCm39)	nonsense	probably null
R6737:Muc5b	UTSW	7	141,411,236 (GRCm39)	missense	unknown
R6763:Muc5b	UTSW	7	141,416,021 (GRCm39)	missense	probably benign	0.01
R6817:Muc5b	UTSW	7	141,416,650 (GRCm39)	missense	probably benign	0.06
R6819:Muc5b	UTSW	7	141,412,600 (GRCm39)	missense	unknown
R6916:Muc5b	UTSW	7	141,418,454 (GRCm39)	missense	possibly damaging	0.71
R7030:Muc5b	UTSW	7	141,396,192 (GRCm39)	missense	unknown
R7116:Muc5b	UTSW	7	141,417,487 (GRCm39)	missense	probably benign	0.10
R7134:Muc5b	UTSW	7	141,411,391 (GRCm39)	missense	unknown
R7146:Muc5b	UTSW	7	141,417,704 (GRCm39)	missense	possibly damaging	0.96
R7168:Muc5b	UTSW	7	141,417,754 (GRCm39)	missense	probably benign	0.01
R7182:Muc5b	UTSW	7	141,396,382 (GRCm39)	missense	unknown
R7189:Muc5b	UTSW	7	141,414,798 (GRCm39)	nonsense	probably null
R7207:Muc5b	UTSW	7	141,416,602 (GRCm39)	missense	probably benign	0.01
R7232:Muc5b	UTSW	7	141,419,866 (GRCm39)	missense	possibly damaging	0.53
R7260:Muc5b	UTSW	7	141,396,385 (GRCm39)	missense	unknown
R7269:Muc5b	UTSW	7	141,411,272 (GRCm39)	missense	unknown
R7273:Muc5b	UTSW	7	141,405,307 (GRCm39)	missense	unknown
R7278:Muc5b	UTSW	7	141,411,239 (GRCm39)	missense	unknown
R7307:Muc5b	UTSW	7	141,396,031 (GRCm39)	missense	unknown
R7323:Muc5b	UTSW	7	141,412,444 (GRCm39)	missense	unknown
R7374:Muc5b	UTSW	7	141,416,863 (GRCm39)	missense	probably benign	0.10
R7376:Muc5b	UTSW	7	141,426,287 (GRCm39)	missense	possibly damaging	0.53
R7382:Muc5b	UTSW	7	141,412,685 (GRCm39)	missense	unknown
R7481:Muc5b	UTSW	7	141,414,908 (GRCm39)	missense	unknown
R7497:Muc5b	UTSW	7	141,415,250 (GRCm39)	missense	possibly damaging	0.92
R7554:Muc5b	UTSW	7	141,412,513 (GRCm39)	missense	unknown
R7571:Muc5b	UTSW	7	141,400,986 (GRCm39)	missense	unknown
R7598:Muc5b	UTSW	7	141,412,999 (GRCm39)	missense	unknown
R7609:Muc5b	UTSW	7	141,415,466 (GRCm39)	missense	possibly damaging	0.86
R7615:Muc5b	UTSW	7	141,418,629 (GRCm39)	nonsense	probably null
R7618:Muc5b	UTSW	7	141,421,334 (GRCm39)	missense	probably benign	0.01
R7651:Muc5b	UTSW	7	141,417,760 (GRCm39)	missense	possibly damaging	0.75
R7692:Muc5b	UTSW	7	141,406,966 (GRCm39)	missense	unknown
R7731:Muc5b	UTSW	7	141,411,042 (GRCm39)	critical splice acceptor site	probably null
R7746:Muc5b	UTSW	7	141,415,976 (GRCm39)	missense	probably benign	0.10
R7748:Muc5b	UTSW	7	141,401,542 (GRCm39)	missense	unknown
R7774:Muc5b	UTSW	7	141,396,116 (GRCm39)	missense	unknown
R7783:Muc5b	UTSW	7	141,411,078 (GRCm39)	missense	unknown
R7834:Muc5b	UTSW	7	141,412,807 (GRCm39)	missense	unknown
R7872:Muc5b	UTSW	7	141,399,850 (GRCm39)	missense	unknown
R7935:Muc5b	UTSW	7	141,400,569 (GRCm39)	missense	unknown
R8026:Muc5b	UTSW	7	141,417,373 (GRCm39)	missense	probably benign	0.03
R8036:Muc5b	UTSW	7	141,421,478 (GRCm39)	missense	possibly damaging	0.73
R8081:Muc5b	UTSW	7	141,417,743 (GRCm39)	missense	possibly damaging	0.88
R8096:Muc5b	UTSW	7	141,403,292 (GRCm39)	missense	unknown
R8101:Muc5b	UTSW	7	141,418,912 (GRCm39)	missense	possibly damaging	0.53
R8112:Muc5b	UTSW	7	141,415,765 (GRCm39)	missense	possibly damaging	0.53
R8131:Muc5b	UTSW	7	141,396,146 (GRCm39)	missense	unknown
R8170:Muc5b	UTSW	7	141,414,737 (GRCm39)	missense	unknown
R8171:Muc5b	UTSW	7	141,414,737 (GRCm39)	missense	unknown
R8191:Muc5b	UTSW	7	141,421,421 (GRCm39)	missense	probably benign	0.18
R8237:Muc5b	UTSW	7	141,411,697 (GRCm39)	missense	unknown
R8342:Muc5b	UTSW	7	141,414,602 (GRCm39)	missense	unknown
R8343:Muc5b	UTSW	7	141,417,898 (GRCm39)	missense	probably benign	0.28
R8389:Muc5b	UTSW	7	141,415,516 (GRCm39)	missense	possibly damaging	0.53
R8396:Muc5b	UTSW	7	141,405,552 (GRCm39)	missense	unknown
R8733:Muc5b	UTSW	7	141,417,532 (GRCm39)	missense	possibly damaging	0.68
R8774:Muc5b	UTSW	7	141,418,831 (GRCm39)	missense	probably benign	0.18
R8774-TAIL:Muc5b	UTSW	7	141,418,831 (GRCm39)	missense	probably benign	0.18
R8833:Muc5b	UTSW	7	141,412,105 (GRCm39)	missense	unknown
R8884:Muc5b	UTSW	7	141,403,156 (GRCm39)	missense	unknown
R8907:Muc5b	UTSW	7	141,417,875 (GRCm39)	missense	probably benign	0.21
R8944:Muc5b	UTSW	7	141,421,115 (GRCm39)	missense
R9025:Muc5b	UTSW	7	141,426,209 (GRCm39)	missense	probably damaging	0.98
R9044:Muc5b	UTSW	7	141,411,795 (GRCm39)	missense	unknown
R9117:Muc5b	UTSW	7	141,423,070 (GRCm39)	missense	possibly damaging	0.73
R9145:Muc5b	UTSW	7	141,411,350 (GRCm39)	missense	unknown
R9154:Muc5b	UTSW	7	141,417,974 (GRCm39)	missense	probably damaging	0.98
R9177:Muc5b	UTSW	7	141,399,075 (GRCm39)	missense	unknown
R9190:Muc5b	UTSW	7	141,411,939 (GRCm39)	missense	unknown
R9204:Muc5b	UTSW	7	141,410,129 (GRCm39)	missense	unknown
R9260:Muc5b	UTSW	7	141,405,255 (GRCm39)	missense	unknown
R9331:Muc5b	UTSW	7	141,411,475 (GRCm39)	missense	unknown
R9366:Muc5b	UTSW	7	141,417,041 (GRCm39)	missense	probably benign	0.01
R9402:Muc5b	UTSW	7	141,399,151 (GRCm39)	missense	unknown
R9462:Muc5b	UTSW	7	141,415,216 (GRCm39)	missense
R9463:Muc5b	UTSW	7	141,405,503 (GRCm39)	missense	unknown
R9490:Muc5b	UTSW	7	141,425,497 (GRCm39)	missense	probably benign	0.33
R9523:Muc5b	UTSW	7	141,396,116 (GRCm39)	missense	unknown
R9548:Muc5b	UTSW	7	141,421,648 (GRCm39)	missense	possibly damaging	0.52
R9591:Muc5b	UTSW	7	141,412,516 (GRCm39)	missense	unknown
R9602:Muc5b	UTSW	7	141,417,211 (GRCm39)	missense	probably benign	0.11
R9664:Muc5b	UTSW	7	141,409,279 (GRCm39)	missense	unknown
R9703:Muc5b	UTSW	7	141,425,535 (GRCm39)	missense	possibly damaging	0.53
R9713:Muc5b	UTSW	7	141,416,678 (GRCm39)	missense	probably benign	0.01
R9789:Muc5b	UTSW	7	141,415,330 (GRCm39)	missense	possibly damaging	0.95
R9800:Muc5b	UTSW	7	141,415,480 (GRCm39)	missense	possibly damaging	0.53
Z1088:Muc5b	UTSW	7	141,415,951 (GRCm39)	missense	probably benign	0.01
Z1176:Muc5b	UTSW	7	141,396,442 (GRCm39)	missense	unknown
Z1177:Muc5b	UTSW	7	141,416,910 (GRCm39)	missense	probably benign	0.04

Predicted Primers

Posted On

2013-08-19